Purpose: This study interprets how infection control nurses (ICNs) experienced and understood administrative support during infection-prevention activities, and to clarify how this support influenced their practice, well-being, and professional identity in post-pandemic clinical settings. Methods: This qualitative study used interpretative phenomenological analysis. Through purposive and snowball sampling, six ICNs from tertiary and general hospitals in Korea, each with at least 3 years of ICN experience and direct involvement in the COVID-19 response, participated in two semi-structured, in-depth interviews between August 20 and September 3, 2025. Interviews were audio-recorded, transcribed verbatim, and analyzed first idiographically, then across cases, following Smith’s procedures. Reflexive notes and an audit trail ensured analytic rigor. Results: Analysis identified six interrelated themes, expressed in participants’ terms and specific work contexts. First, the realities and challenges of infection-prevention practice reflected ongoing workload pressure, delayed outcome visibility, and crisis-driven surges that caused moral strain. Second, meanings and experiences of managerial support indicated that support was genuine when leaders listened, made prompt decisions, and backed ICN judgments; its absence led to isolation and role fatigue. Third, the operation of resources and institutional arrangements showed that staffing, budgets, equipment, and clear decision pathways either enabled or limited timely, consistent action. Fourth, organizational culture and interprofessional barriers revealed that hierarchical norms, siloed routines, and skepticism hindered cooperation, while open, learning-oriented environments supported the adoption of precautions. Fifth, emotional turbulence and professional identity highlighted tensions between enforcement and caregiving roles, which undermined self-efficacy; recognition and small practice successes restored pride in the specialized role. Finally, conditions for recovery and change emphasized that practical support and formal acknowledgment-along with after-action reviews, protocol updates, cross-disciplinary drills, and aligned incentives-helped transform individual learning into resilient, sustainable organizational capability. Conclusion: For ICNs, administrative support extends beyond resources by providing authority, psychological safety, and feasibility for infection-prevention efforts. To maintain prevention measures beyond crises, hospitals should ensure governance structures, rapid decision-making channels, stable staffing and budgets, and regular debriefings with protocol updates. Connecting infection-control performance to recognition and professional development may reduce burnout, strengthen professional identity, and enhance patient safety.

본 연구는 간호대학생을 대상으로 감염관리 지식, 학업적 자기효능감, 감염관리 수행자신감의 수준을 파악하고, 감염관리 수행자신감에 영향을 미치는 요인을 확인하고자 하였다. 184명의 간호대학생 을 대상으로 2024년 11월 28일부터 12월 20일까지 설문조사를 실시하였고, 수집된 자료는 ANOVA, independent t-tests, Pearson 상관분석, 다중회귀분석을 통해 분석하였다. 본 연구 결과, 간호대학생의 감염관리 수행자신감은 감염관리 지식 및 학업적 자기효능감과 유의한 정적 상관 관계를 보였으며, 감염 관리 지식과 학업적 자기효능감 또한 정적 상관 관계를 나타냈다. 감염관리 수행자신감에 유의한 영향을 미치는 요인은 학업적 자기효능감, 감염관리 지식, 전공만족도 순으로 확인되었고, 이 모형의 설명력은 35%(F=34.22, p<.001)였다. 이를 토대로, 간호대학생의 감염관리 수행자신감 강화를 위해서는 감염관리 지식뿐만 아니라 학업적 자기효능감을 증진할 수 있는 교육적 중재가 개발되어야 하며, 동시에 전공만족 도 향상을 위한 지원 방안을 마련할 필요가 있다.

본 연구에서는 국내 떫은감(Diospyros kaki Thunb.) 재배지 4개 지역의 9개 임·농가에서 총 132본의 시료를 채취하여 주요 바이러스 및 바이로이 드 감염 여부를 검정하였다. 바이러스 2종(PeCV, PeVA)과 바이로이드 1종(CVd-VI)의 감염을 확인하기 위해 종 특이적 프라이머를 이용한 RT-PCR 을 수행하였다. 그 결과 3종의 병원체가 모두 검출되지 않은 개체는 53본(40.2%)이었다. 감염원별로는 PeCV가 39본(29.6%), PeVA가 18본 (13.6%), CVd-VI가 55본(41.0%)에서 검출되었으며(중복 포함), 지역 간 감염 양상에는 차이를 보였다. 경북 청도군 재배지에서는 단독 감염 13본(37.1%), 복합 감염 22본(62.9%)으로 복합 감염의 비율이 높았으나, 전남 영암군에서는 PeVA 단독 감염 6본을 제외한 37본에서 병원체가 검출되지 않았다. 이러한 떫은감 재배지의 바이러스 및 바이로이드 감염 양상 자료는 향후 병원체 전염 방지 및 우수 개체 증식을 위한 무병묘 육성 연구의 기초자료로 활용될 수 있을 것이다.

Grapevine l eaf rust (GLR) c aused b y Phakopsora euvitis diminishes fruit quality and reduces yield in viticulture, making it one of the world’s most significant fruit crop threats. To develop GLR-resistant grape varieties, substantial efforts have been made to select rust-resistant genes and determine effective strategies f or achieving durab le resistance in grapevines. This study aims to identify genetic resources resistant to GLR by investigating disease incidence in vineyards and symptom development in grapevines inoculated with pathogens. Fifty-seven genotypes from Ampelopsis brevipedunculata, Vitis acerifolia, V. aestivalis, V. amurensis, V. cinerea, V. coignetiae, V. flexuosa, V. labrusca, V. labruscana, V. rotundifolia, and V. vinifera were evaluated for rust disease incidence over four years (2021 –2024) at Yeunganm University. Three plants per genotype were potted and sprayed with a pathogen suspension to assess disease incidence on their adaxial leaf surfaces in a greenhouse. Variation in resistance to GLR was observed among genotypes within each species. Resistant genotypes of V. coignetiae exhibited no symptoms on their leaves, while severe infections were noted in the leaves of susceptible genotypes of A. brevipedunculata, V. amurensis, V. flexuosa, V. labruscana, and V. vinifera. None of the tested V. rotundifolia genotypes displayed yellow pustules and remained unaffected for three weeks after artificial inoculation. These findings highlight the potential of V. rotundifolia and V. coignetiae as valuable genetic resources for breeding rust-resistant grapevines. Chlorophyll content was comparable across all uninfected genotypes. While resistant genotypes maintained relatively stable chlorophyll levels, the average chlorophyll content in the majority of susceptible genotypes was significantly lower following inoculation than before. This negative relationship indicates a general decline in photosynthetic capacity due to disease development in grapevines. Identifying resistant genotypes among both resistant and susceptible genotypes across different Vitis species provides crucial insights for developing new grape varieties with improved resistance to GLR.

Amitriptyline hydrochloride (AMT), a tricyclic antidepressant, is known to exhibit antimicrobial effects against a wide range of bacterial species. This study aims to evaluate the effect of AMT on Brucella (B.) abortus infection in RAW 264.7 cells and ICR mice, which has not yet been clearly characterized. The results showed that all tested concentrations of AMT had no direct bactericidal effect on B. abortus survival at any incubation time point. Interestingly, RAW 264.7 cells pre-treated with a non-toxic high concentration of AMT before B. abortus infection showed a significant reduction in the phagocytosis of B. abortus at 20 min post-infection, compared to untreated cells. However, AMT treatment did not affect the intracellular replication of B. abortus compared to the control cells. Based on the reduced bacterial uptake observed in-vitro, an in-vivo experiment was conducted to assess whether daily oral administration of AMT at a dose of 20 mg/kg could inhibit B. abortus growth in ICR mice. The results showed that AMT treatment slightly increased both organ weights and bacterial loads, suggesting possible systemic effects of prolonged AMT exposure. In summary, these preliminary results provide initial insight into the potential effects of AMT on B. abortus infection both in-vitro and in-vivo. Therefore, further study should focus on dose optimization in-vivo and exploration of the underlying cellular mechanisms involved in AMT-mediated inhibition of phagocytosis during Brucella infection.

Purpose: This study was conducted to confirm the effects of patient safety simulation education on nursing students’s attitude of patient safety, confidence in performance of patient safety, confidence in performance multidrug-resistant bacterial infection control, and nursing professionalism. Methods: In this study, 89 students from the 4th grade of the nursing department at one university participated, and the data collection period was from August 20 to August 30, 2023. The collected data were analyzed using R 4.3.2 version and by descriptive statistics, independent t-test, Pearson’s correlation coefficients. Results: After education, the subjects' nursing professionalism(t=-5.95, p<.001), attitude of patient safety(t=-3.59, p<.001), confidence in performance of patient safety(t=-3.90, p<.001), and confidence in performance multidrugresistant bacterial infection control(t=-5.55, p<.001) increased statistically significantly. After education, there was a positive correlation between nursing professionalism, attitude of patient safety(r=.43, p<.001), confidence in performance of patient safety(r=.64, p<.001), confidence in performance multidrug-resistant bacterial infection control(r=.41, p=<.001). The relationship between attitude of patient safety, confidence in performance of patient safety(r=.47, p<.001), confidence in performance multidrug-resistant bacterial infection control(r=.37, p=<.001) showed a positive correlation. Confidence in performance of patient safety, confidence in performance multidrug-resistant bacterial infection control(r=.80, p<.001) showed a positive correlation. Conclusion: Through this study, in order to strengthen effective patient safety management behavior, it is necessary to find ways to increase immersion and proactiveness in education by developing and applying various scenarios related to patient safety in nursing management simulation education.