We compared the spatial distribution of several heat stress indices (the Wet-Bulb Globe Temperature(WBGT) index, Environmental Stress Index (ESI), and Modified Discomfort Index(MDI)) for the heat wave of June 6 ~August 26, 2016, in Daegu. We calculated the heat stress indices using data from the high density urban climate observation network in Daegu. The observation system was established in February. 2013. We used data from a total of 38 air temperature observation points (23 thermometers and 18 automatic weather stations). The values of the heat stress indices indicated that the danger level was very high from 0900-2000h in downtown Daegu. The daily maximum value of the WBGT was greater than or equal to 35℃ The differences in the heat stress indices from downtown and rural areas were higher in the daytime than at nighttime. The maximum difference was about 4 before and after 1400h, and the time variations of the heat stress indices corresponded well. Thus, we were able to confirm that the ESI and MDI can be substituted with the WBGT index.

Inflammation is the first response of the immune system to infection or irritation in our body. The use of medicinal plants has been widely applied as an alternative source for drug development. One of marine natural resources, the anti-inflammatory effect of Ishige sinicola ethanol extract (ISEE), was evaluated by using LPS-induced RAW 264.7 cell and mice model. As a result, the production of nitric oxide (NO) and pro-inflammatory cytokines (IL-6, IL-1β, TNF-α) were inhibited with increasing concentration of ISEE without any cytotoxicity. Furthermore, ISEE suppressed the expression of not only inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), nuclear factor-kappa B (NF-κB) p65, and mitogen-activated protein kinases (MAPKs), including extracellular signal-regulated kinase (ERK) 1/2, p38, and c-Jun N-terminal kinase (JNK) in a dose-dependent manner. In mice ear edema test, the formation of edema was reduced at the highest dosage of ISEE and the reduction of the number of infiltrated mast cells was observed in histological analysis. These results indicate that ISEE has a potent anti-inflammatory activity and can be used as a pharmaceutical material for many kinds of inflammatory disease.

We studied the distribution of air temperature using the high density urban climate observation network data of Daegu. The observation system was established in February 2013. We used a total of 38 air temperature observation points (23 thermometers and 18 AWSs). From the distribution of monthly averaged air temperatures, air temperatures at the center of Daegu were higher than in the suburbs. The daily minimum air temperature was more than or equal to 25℃ and the daily maximum air temperature was more than or equal to 35℃ at the elementary school near the center of Daegu. Also, we compared the time elements, which are characterized by the diurnal variation of surface air temperature. The warming and cooling rates in rural areas were faster than in urban areas. This is mainly due to the difference in surface heat capacity. These results indicate the influence of urbanization on the formation of the daily minimum temperature in Daegu.

The extensive construction works of container terminals progressed since 2006 was converted to small scaled construction works or reclaiming works since 2012 in Busan New Port area. To investigate changes in activity of otters with the change of construction work scales, the linear densities of spraints at 15 localities of 5 areas (I-V) near the Busan New Port construction areas were surveyed during the period from 2012 to 2016. As the results, the average linear density of spraints has a tendency to increase since 2014. That is, the linear densities of spraints have increased at the area II and IV where the reclaiming works have been progressed, although have decreased or unchanged in the areas Ⅰ, Ⅱ and Ⅴ where small scaled construction works have been progressed. Based on the fact that there were habitats at the Honamdo in the area II and the Yeondo in the area IV, otters seemed to restore their activities around the habitats as the center regardless of the reclaiming works.

In this study, bacterial growth was assessed by flow cytometry analysis of fluorescent probes-stained bacteria. Flow cytometry has many advantages of rapid analytical time, a low standard deviation, and highly sensitive detection of live and Dead E.coli over colony forming assay. When untreated bacteria were stained by using Thiazole Orange (TO) and Propidium Iodide (PI), double staining had a short analytical time as compared with that of single staining while its error rate was similar to that of single staining. Through double staining experiments, it was determined that optimal concentrations for TO and PI staining were 420 nM and 9.6 μM, respectively.

본 연구의 목적은 초등학교 통합학급 학생을 대상으로 장애수용태도 향상을 위한 독서치료 활용 집단상담 프로그램을 구안하여 적용하고 그 효과를 검증하는 데 있다. 프로그램 개발 과 정은 조사, 분석, 설계, 구안, 적용의 5단계로 이루어졌다. 조사단계에서는 다양한 선행연구를 고찰하고 초등학교 통합학급 학생 79명을 대상으로 요구조사를 실시하였다. 분석단계에서는 프 로그램 목적, 회기별 목표, 회기 수를 결정하였다. 설계 및 구안단계에서는 프로그램의 목적, 목표, 회기별 목표에 따라 선별된 활동안을 이론 전문가와 현장전문가의 자문과 예비적용 과정 을 거쳐 수정·보완하여 총 12회기로 구성된 최종프로그램을 구안하였다. 적용단계에서는 N시 소재의 초등학교 4학년 2개 통합학급을 대상으로 실험집단과 통제집단을 구성하여 프로그램을 실시하였다. 프로그램 전․후에 장애수용태도 검사를 실시하고 혼합변량분석(Mixed ANOVA) 을 통해 자료를 처리하였으며 참가자의 경험 보고서와 상담자 관찰내용을 분석하였다. 그 결과 초등학교 통합학급 학생의 장애수용태도 향상을 위한 독서치료 활용 집단상담 프로그램은 장 애수용태도 향상에서 유의한 효과가 있었다.

This study evaluates heavy metal(Cu and Cr) adsorption characteristics produced from food waste charcoal extracted in an optimal operation condition after analyzing activated charcoal of iodine adsorption and heavy metals that derived from an activation process of carbide by the developed by-products of food waste treatment facility using the methods from previous studies. As experiment apparatus, this study used a tube-shaped high temp furnace. The mixing ratio of by-products of food waste treatment facility, carbide, and activation component(ZnCl2) was 1:1. The experiment was proceeded as adjusting the activation temperature from 400 to 800℃ and activation time from 30 to 120 minutes. The optimal activation condition for iodine absorption was 90 minutes at 700℃ and by using the produced food waste charcoal, this study conducted an experiment on absorption of heavy metals (Cu and Cr) as changing pH of artificial wastewater and stirring time. As a result, pH 7 showed the highest heavy metal decontamination ratio and in terms of stirring time, it revealed balance adsorption after 10 minutes. This result can be particularly applied as basic data for recyclability of high concentration organic waste, by-products of food waste treatment facility, as an food waste charcoal.

In this study, we evaluated the antidiabetic effect of a submerged culture of Ceriporia lacerata mycelium (CL01) on hematological indices, as well as protein and mRNA expression of the insulin-signaling pathway, in db/db mice. After CL01 was administrated for 4 weeks, blood glucose levels decreased consistently, and plasma insulin and c-peptide levels each decreased by roughly 55.8%, 40% of those in the negative control (p<0.05). With regard to HOMA-IR, an insulin resistance index, insulin resistance of the CL01-fed group improved over that of the negative control group by about 62% (p<0.05). In addition, we demonstrated that the protein expression levels of pIR, pAkt, pAMPK, and GLUT4 and the mRNA expression levels of Akt2, IRS1, and GLUT4 in the muscle cells of db/db mice increased in the CL01-fed group compared to the corresponding levels in the control group. These results demonstrate that CL01 affects glucose metabolism, upregulates protein and gene expression in the insulin-signaling pathway, and decreases blood glucose levels effectively by improving insulin sensitivity. More than 90% of those who suffer from type 2 diabetes are more likely to suffer from hyperinsulinemia, hypertension, obesity, and other comorbidities because of insulin resistance. Therefore, it is possible that CL01 intake could be used as a fundamental treatment for type 2 diabetes by lowering insulin resistance, and these results may prove be useful as basic evidence for further research into the mechanisms of a cure for type 2 diabetes.

본 연구는 자신을 교과전문가로 인식하는 중학교 교사들에게 있어서 교장의 수업지도성은 교사의 교수효능감과 교직만족을 증대시키는 요인으로 작용할 수 있을 것이라는 가정 하에, 세 변인 간 구조적 관계를 밝힐 목적으로 수행되었다. ｢학교교육 실태 및 수준 분석｣ 3주기 중학 교 데이터(2010년)의 교사 6,357명 자료를 기술통계, 확인적 요인분석, 구조방정식모형, 매개효 과 분석, 부트스트래핑을 활용하여 분석하였다. 연구결과, 첫째, 교장의 수업지도성과 교사의 교수효능감 및 교직만족도에 대한 교사들의 인식은 대체로 긍정적이었으나, 상대적으로 수업지 도성의 하위영역 중 ‘긍정적 학교 풍토 조성’과 교직만족도에 대한 인식은 상대적으로 덜 긍정 적이었다. 둘째, 교장의 수업지도성은 교사의 교수효능감과 교직만족도에 긍정적 영향을 미치 고, 교사의 교수효능감 역시 교직만족도에 긍정적 영향을 미치는 것으로 나타났다. 셋째, 교사 의 교수효능감은 교장의 수업지도성이 교사의 교직만족도에 미치는 영향을 부분매개하는 것으 로 확인되었다. 연구결과를 토대로 교장의 수업지도성과 교사의 교직만족 제고를 위한 지원이 필요하다는 내용을 위시한 정책적 제언을 제시하였다.

본 연구는 rutin 및 rutin 대사체인 DHPAA, HPAA, DHT, HVA가 버섯 유래 tyrosinase 활성과 마우스 피부표피 세포주인 JB6 P+ 세포의 증식에 미치는 영향에 대해 살펴보았다. HVA가 버섯유래 티로시나제 저해활성이 가장 우수한 것으로 관찰되었으며, DHPAA, HPAA, rutin, DHT 순서로 저해효능을 나타내었다. DHT를 제외한 rutin 및 rutin 대사체들 모두 100 μM 까지 세포 독성이 관찰되지 않은 것으로 관찰되었으며, DHT는 50 또는 100 μM에서 세포증식을 저해하였으나 그 이하의 농도에서는 세포독성을 유도하지 않았다. 따라서 본 연구결과, rutin 대사체 모두 세포 독성이 없는 수준에서 버섯 유래 티로시나제 활성을 효과적으로 억제하였으므로, 앞으로 미백제제로 활용될 수 있을 것으로 기대된다.

The objective of this study was to predict land use change based on the land use change scenarios for the Hwangguji river watershed, South Korea. The land use change scenario was derived from the representative concentration pathways (RCP) 4.5 and 8.5 scenarios. The CLUE (conversion of land use and its effects) model was used to simulate the land use change. The CLUE is the modeling framework to simulate land use change considering empirically quantified relations between land use types and socioeconomic and biophysical driving factors through dynamical modeling. The Hwangguji river watershed, South Korea was selected as study area. Future land use changes in 2040, 2070, and 2100 were analyzed relative to baseline (2010) under the RCP4.5 and 8.5 scenarios. Binary logistic regressions were carried out to identify the relation between land uses and its driving factors. CN (Curve number) and impervious area based on the RCP4.5 and 8.5 scenarios were calculated and analyzed using the results of future land use changes. The land use change simulation of the RCP4.5 scenario resulted that the area of urban was forecast to increase by 12% and the area of forest was estimated to decrease by 16% between 2010 and 2100. The land use change simulation of the RCP8.5 scenario resulted that the area of urban was forecast to increase by 16% and the area of forest was estimated to decrease by 18% between 2010 and 2100. The values of Kappa and multiple resolution procedure were calculated as 0.61 and 74.03%. CN (Ⅲ) and impervious area were increased by 0-1 and 0-8% from 2010 to 2100, respectively. The study findings may provide a useful tool for estimating the future land use change, which is an important factor for the future extreme flood.

세리포리아 락세라타 균사체 배양물(CL01)의 혈당 강하 효과를 확인하기 위해 in-vitro 및 in-vivo 시험을 수행하였 다. CL01이 INS-1 세포에서 덱사메타손에 의한 세포 사멸 방지 효과를 나타냈으며 3T3-L1 세포에서는 당수송체인 GLUT4의 발현을 증가시켰다. 제 2형 당뇨 마우스를 4 그룹 (normal control (G1), negative control (G2), positive control (G3), CL01 250 mg/kg (G4))으로 나누어 6주간 매일 CL01 을 투여한 후 혈중 지표를 확인한 결과, CL01 섭취군은 체중, 사료 및 물 섭취량에서 음성대조군 대비 유의적인 차이를 보이지 않았다. 투여 5주 후 CL01 섭취군의 혈당이 음성대조군 대비 유의적인 감소를 보였으며 6주 경과 시 혈중 인슐린은 36% 증가하였고 혈중 C-peptide 농도는 18% 감소하였다. 경구 당 부하 시험 결과 CL01 섭취군의 혈당이 음성대조군 대비 15% 감소하였다. 이상의 결과를 통해 CL01이 베타 세포를 증식시켜 인슐린 분비를 촉진하고 혈 당을 낮추는 효과가 있음을 알 수 있다.

기상청의 한반도 기후변화 전망보고서(2012)에 따르면 온실가스 배출이 현재와 같이 지속될 경우(RCP 8.5) 21세기 후반(2071-2100) 우리나라의 평균기온은 현재보다 5.3℃ 상승하고, 폭염일수는 30.3일 증가하여, 폭염으로 인한 강도가 한층 심화될 것으로 예측되고 있다. 폭염으로 인한 피해를 저감하기 위하여 우리나라에서는 2005년부터 국민안전처(구 소방방재청)에서 범정부적인 폭염대응 종합대책을 수립하여 시행하고 있다. 또한, 기관별, 지자체별로 각각 폭염대응정책 마련을 통해 폭염으로 인한 피해를 최소화하려는 노력을 하고 있다. 본 연구의 목표는 여름철 기온 상승으로 인한 폭염에 대응하고, 중장기적으로 폭염 피해를 경감할 수 있는 대책을 발굴하는 것이다. 이에 본 연구는 국내·외 구조적, 비구조적 폭염대책을 비교·분석하고, 국내의 폭염대책의 현황과 문제점을 조사하였다. 특히, 대표적인 폭염대책 중 하나인 무더위쉼터의 공간적 분포와 이용현황을 분석하였다. 또한, GIS를 이용하여 지역별 폭염일수, 취약계층 비율(65세 이상 고령자, 독거노인, 기초생활수급자), 재정자립도 등의 폭염취약지표를 이용한 폭염취약성을 분석하였으며, 폭염취약지역과 무더위쉼터 분포와의 공간적 상관관계를 분석하였다. 본 연구를 통한 기존 폭염대책의 개선방안 및 새로운 대책은 중장기적으로 폭염피해를 저감하는데 기여할 수 있을 것으로 기대된다.

This study examines the trends of elementary and middle school teachers’ participation in content-focused professional development (PD) in Korea using teacher samples from the first and second cycles of The Study on the Actual Status and Quality in School Education. Using chi-square tests and t-tests, we found 1) both elementary and middle school teachers tended to participate in content-focused PD more actively than non-content-focused PD; 2) middle school teachers had a decreasing pattern of participation in content-focused PD; 3) elementary school teachers showed mixed results in participation in content-focused PD; and 4) elementary school teachers tended to participate in content-focused PD more actively than middle school teachers. More support for both middle and elementary school teachers is needed to encourage participation in content-focused PD more actively.

Purpose: The purpose of the present study was to examine the physical and psychological benefits afforded by a 6-week yoga program for breast cancer survivors. Methods: Eligible participants (per-screened) were to the intervention group 17. All participants completed pre- and post-testing assessments immediately before and after the Mindfulness yoga program. Statistical analyses were paired samples t-test by SPSS 19.0. Results: The Mindfulness yoga program participants(female) included primarily breast cancer survivors, on average 46.5 months post-diagnosis. Significant differences between pre and post at post-intervention were seen only in psychosocial(i.e. QOL; Role function, Appetite loss, Constipation and PSQI) Finally, there were also significant improvements in the program participants from pre- to post-intervention on physical variables(Weight, BMI). Conclusion: The mindfulness yoga program has a positive effect on Quality of life in Breast cancer survivors. Future research might attempt to include control group and a longer program duration.

To investigate the effects of octylphenol and nonylphenol on the reproduction of the striped field mouse, the mice were subcutaneousely injected with 4-t-octylphenol 800 mg/kg (OP800), nonylphenol 900 mg/kg (NP900) or OP800 + NP900 (OPNP), respectively, in two times a week for 2 months. As the results, there were no differences between the control and the compound-treated groups in the body weight in both sexes, and the GSI (gonadosomatic index) and SVI (seminal vesicles index) in the adult males. But histological abnormalities of the reproductive organs in the mice seems to be related to the compound. This suggestion is supported by the facts that most mice treated with the compounds had only a small number of spermatozoa in the shrunken epididymal tubules. In addition, the shrunken reproductive organ in one mouse treated with the NP, suggests that the abnormalities in the wild striped field mice might be induced by the compound. Furthermore, it is indicated that the compounds must be toxicants to inhibit pregnancy, judging from the fact that all the mice treated with the compounds had failed to deliver.

국토해양부에서는 NDGPS 서비스의 광역화와 상용화를 위하여 2012년 현재 지상파 DMB 기반 DGPS 서비스를 구축하여 전국적으로 실험방송을 하고 있다. 이 연구에서는 저가의 GPS 수신 장비를 사용하여 지상파 DMB 기반 DGPS 서비스를 이용한 동적환경에서의 이동측위를 수행하고 정확도를 평가하였다. GPS 단독측위, NTRIP 기반의 단일기준국 NDGPS 측위, 그리고 지상파 DMB 기반의 가상기준국 DGPS 측위를 동시에 수행하였으며 고정밀 측위 결과와의 비교를 통해 수평오차를 산출하였다. 그 결과 GPS 단독, NTRIP-DGPS, DMB-DGPS 측위의 수평오차가 DMB 송출간격이 3초일 때 2.3m, 1.0m, 0.7m, 1초일 때 2.0m, 1.2m, 0.8m로 나타났다. 이를 통해 해당 서비스를 이용할 경우에 단일기준국 기반의 NDGPS 서비스를 이용하는 경우보다 수평 정확도가 향상되는 것을 확인하였다.

Dieldrin, one of the organochlorine pesticides (OCPs), induced the damages in neuroblastoma cells and DNA damages in lymphocytes. The ethanol extracts of A. sessiliflorus leaves were examined for the suppressive effects on the dieldrin-induced cell damages. Moreover, the extract was used to test whether it might inhibit the oxidative DNA damage of lymphocytes using Comet assay. The cell and DNA damage by dieldrin were suppressed in vitro upon treating A. sessiliflorus extract. This result suggests that A. sessiliflorus extract might be useful to reduce dieldrin toxicity.

레몬 오일과 유칼립투스 오일은 노화방지, 살균작용과 같은 다양한 효능을 가진 것으로 알려져 있다. 그러나 특정 피부 상재균에 대한 항균 효과와 항산화 효과는 아직 연구가 미비한 상황이다. 따라서 본 연구에서는 DPPH 라디칼 소거능 실험과 paper disc 방법을 이용하여 단일 오일들과 혼합오일의 항산화와 항균 활성을 검증하고자 하였다. 레몬 오일은 높은 DPPH 소거능을 보였으나 유칼립투스 오일은 아주 약한 소거능을 보였다. 두 오일을 혼합한 경우에는 효과가 증대되지 않았다. Paper disc 기법을 이용한 항균 효과 시험에서는 두 오일 모두 Candida albicans (C. albicans)와 Propionibacterium acnes (P. acne)에서 항균력이 우수하며 농도의존적인 효능이 있음을 알 수 있었다. 또한, 두 오일을 혼합 하였을 때 P. acne에 대하여 항균 활성이 상승됨을 알 수 있었다. 본 연구의 결과를 종합적으로 볼 때, 레몬 오일과 유칼립투스 오일의 혼합 오일은 천연성분으로서 균으로 야기된 문제성 피부나 여드름 피부를 개선시키는데 효과적일 것으로 사료된다.