담관 담석을 제거하기 위해서는 선택적 담관삽입술(selective cannulation)에 성공한 뒤 내시경 유두괄약근 절개술을 시행하게 된다. 내시경 유두괄약근 절개술은 출혈, 천공, 췌장염 등의 합병증을 발생시킬 수 있다. 이러한 합병증의 발생을 줄이고 시술의 성공률을 높이기 위하여 다양한 형태의 내시경 괄약근 절개기와 절개를 위해 사용되는 전류 발생기가 개발되었다. 또한 절개의 방향과 범위, 절개술에 대한 가이드라인이 정해지고 있다. 괄약근 절개 후 담석의 제거를 위해 사용되는 방법에서 대표적으로 풍선을 이용하는 방법과 바스켓을 이용하는 방법이 있다. 내시경 괄약근 절개술의 기술적 방법을 소개하고, 효과적으로 담석을 제거할 수 있는 대표적인 방법들에 대하여 임상적 적응증과 기술적 방법에 대하여 논하고자 한다.

췌장낭성종양의 병리진단에서 분자병리 검사의 활용은 통상적인 세포 또는 조직 진단이 어려운 경우 점진적으로 확대될 것으로 예상된다. 세포 또는 낭액에서 검사 결과에 필요한 충분한 디오시리보핵산(DNA)이 확보된다면 특정 유전자 변이를 확인해서 췌장낭성종양의 감별 진단이 가능하며 대표적인 유전자 변이에는 KRAS, GNAS, CTNNB1, VHL 변이 등이 있다. 하지만 분자병리 검사를 활용하는 경우에도 임상-영상의학적 소견을 참고하여 기본적인 병리진단을 한 후에, 이를 뒷받침하는 자료로 활용되는 것이 바람직하다. 차세대염기순서분석 검사는 소량의 세포 또는 조직으로 다수의 유전자 변이를 동시에 확인할 수 있는 장점이 있어 사용되는 범위가 확대될 것으로 기대되지만 적절한 정도 관리를 거치지 않으면 위음성의 결과로 보고될 위험성이 있으며 병리의사의 정도 관리를 거친다고 하더라도 30% 내외의 실패율을 보일 수 있다고 보고되어 있다.

정확도 높고, 실용적으로 손쉽게 사용될 수 있는 온수양생 방법을 표준화하고 이를 통한 콘크리트 압축강도 예측방법을 제시하고자 변수 실험을 진행하였다. 전양생 시간, 온수양생 온도, 온수양생 시간에 대한 변수실험을 통해 18시간 전양생 시간, 70℃ 온수양생 온도, 24시간 온수양생시간의 온수양생시험 표준 조건을 제시하였다. 온수양생시험 표준 조건에 대한 추가적인 배합시험을 통해 콘크리트의 압축강도를 조기에 산정할 수 있는 선형 추정식을 산정하였고, 압축강도 추정식의 높은 신뢰도를 확인하였다. 또한, 혼화재 종류 및 혼화재 치환율 변수에 대한 온수양생시험을 통해 온수양생을 통한 콘크리트 압축강도 조기 추정방법은 시멘트 종류, 혼화재 종류 및 치환율, 골재의 종류가 동일한 배합에 대해서만 그 적용이 가능하다는 결론을 도출하였다.

PURPOSES: The purpose of this study is to compare the concentrations of fine particulate matter (PM2.5) at different types of roadside bus stops in an urban environment, and analyze the tendencies in PM2.5 concentrations according to the air quality index. METHODS : To compare and analyze the characteristics of fine particulate matter at roadside bus stops, we collected data such as PM2.5 concentration, temperature, humidity etc., and performed a comparative analysis of their concentration levels at different types of bus stops (a partially closed bus stop with a front and back partition, a partially closed bus stop with only a back partition, and a bus stop with an open space). In addition, the daily variation in fine particulate matter concentration was analyzed. RESULTS: The average daily concentration levels of fine PM2.5 in the target area for a partially closed bus stop with a front and back partition, a partially closed bus stop with a back partition, and a bus stop with an open space were 18.40㎍/㎥ to 108.27㎍/㎥, 22.81㎍/㎥ to 135.51㎍/㎥, and 16.62㎍/㎥ to 81.52㎍/㎥, respectively. According to air quality index levels during the target measurement period, the bus stop with an open space had the least concentration levels of PM2.5 compared to the other bus stops. Furthermore, this study revealed that the PM2.5 concentration levels usually increased during the peak hour period in the morning and gradually increased after 2 pm until the end of the peak hour period at night, regardless of the bus stop type. CONCLUSIONS: Based on the results of this study, we demonstrated the effect of PM2.5 concentration levels on the atmospheric, weather, environmental, and transportation conditions in a target area, and the variation in concentration levels depending on the type of bus stop.

최근 FRP 보강공법의 보강성능 저하 요인으로 발생하는 박리파괴를 방지하고자 다양한 앵커리지 시스템이 개발되고 있다. 본 연구는 기존 사용되고 있는 기계식 정착 앵커와 FRP 앵커를 복합하여 새로운 메커니즘의 Hybrid 앵커모델을 개발하였다. Hybrid 앵커를 개발하기 위해 다양한 종류의 기계식 앵커와 Carbon 및 Aramid 섬유를 조합하였다. 개발된 다양한 앵커모델에 대한 특성을 평가하고자 Pull out 강도 실험을 수행하였다. 예비 실험 결과 Drop-in 앵커와 Undercut 앵커의 경우 낮은 정착력으로 적용에 한계가 있었다. Stud 앵커는 높은 정착력을 확인하였으며, 앵커와 FRP를 결합하기 위해서는 일체화가 중요한 것으로 나타났다. 일체화를 위해 앵커 내부에 홀을 천공하여 FRP rod를 결합하는 형태로 I-Hybrid 앵커를 제작하였다. I-Hybrid 앵커 의 경우 앵커 내부 홀에서 뽑히는 거동을 보였다. 따라서 향후 연구에서 I-Hybrid 앵커가 일체화된다면 FRP 박리파괴 저감에 효과적일 것으로 사료된다.

Recently, a number of recent reports have reported cases of bone marrow defect (BMD) in the mandible. Among the diseases seen by BMD in radiographs, focal osteoporotic bone marrow defect(FOBMD) is asymptomatic, which is discovered incidentally and localized radiolucency. Because it varies in size, shape, trabeculae and border definition, it needs to biopsy to differential diagnose other intraosseous lesions that show radiological bone marrow defects. This cases report discusses the pre-operation considerations in patients planning to implant the mandible and suspected to have FOBMD in radiographs. The following 4 cases in Dental Hospital of Wonkwang University were taken in panoramic and Cone beam computed tomography(CBCT). In all cases, there were radiolucent lesion diagnosed with FOBMD under radiologic differential diagnosis. In three of cases the implant were placed without treatment plan change and one case changed the treatment plan with removable partial denture. BMD is anatomical state that can affect primary stability of implant fixture. During implant placement, it can lead to unexpected results that fixture is fallen into BMD and the nerve may be damaged after implant fixture removal to cause hyperesthesia. Preoperative diagnosis of these lesions by differential diagnosis with panoramic and CBCT can prevent the complications by changing the treatment plan or paying attention to the manipulation during surgery.

Brain abscesses caused by odontogenic infection are a rare and life-threatening condition. When dental patients show neurological symptoms such as decreased consciousness, a brain abscess should be considered as a possible diagnosis. We reported that a 65-year-old man visited the emergency room because of left facial edema, high fever, limitation of mouth opening and decreased consciousness. CT, bone scan, and microbiologic examination revealed that the brain abscess originated from left mandibular osteomyelitis with an apical lesion in tooth #36. It was hard to diagnose the location of odontogenic infection. Because there were no evidence of submandibular abscess which is a common path of mandibular posterior infection, early diagnosis was difficult. MRI and radiographs such as facial CT and brain CT revealed procedure that inflammatory findings progressed through the coronoid process, the temporal space, into the subdural space. We compared the present case to previous cases, articles published after the year 2000 in Korea and abroad were investigated. The patient was treated successfully with extraction of causative teeth, drainage surgery, intravenous antibiotics by collaboration between the department of oral maxillofacial surgery and neurosurgery. It is difficult to diagnose brain abscess because central nervous system can be infected by various pathway. As shown in this case, patients with a brain abscess caused by a dental infection should be diagnosed and treated with a multidisciplinary approach.

Mucinous adenocarcinoma (MAC) refers to a malignant neoplasm that belongs to a subtype of adenocarcinoma which produces mucin. The World Health Organization has classified MAC as a tumor of salivary gland origin and it is extremely rare. Therefore, its characteristics are not well-known. This study reports a case of MAC of minor salivary gland origin, which occurred in the oral commissure of an 82-year-old female patient, and a systematic review on existing cases of MAC of salivary origin. Based on the study’s findings, it is safe to assume that the occurrence of lymph node metastasis is an important factor in determining the prognosis of patients with MAC.

Herbal medicine has been the basis for medical treatments through much of human history, and such traditional medicine is still widely practiced today. Modern medicine makes use of many plant-derived compounds as the basis for pharmaceutical drugs. In traditionally, Achyranthes aspera, Safflower (Carthamus tinctorius) seed and Acanthopanax senticosus have been used for the treatment and prevention of bone-related diseases. In this study, we investigated the pharmacological effect of mixture of Achyranthes aspera, Safflower (Carthamus tinctorius) seed and Acanthopanax senticosus and the other herbs. Two types of enzymes were used to enhance the extraction components of amino acid, mineral content, free sugar, and flavor recovery in extracting natural herbal mixtures(NME). We evaluated regulation of osteogenic differentiation in human bone marrow mesenchymal stem cells using alkaline phosphatase staining, alizarin red S staining and RT-PCR. The CCK-8 assay indicated that NME had no cytotoxicity but increased cell survival. In addition, NME promoted the mineralization and expression of osteogenic differention marker genes in human bone marrow mesenchymal stem cells. Therefore, NME has an effect of promoting proliferation and osteogenic differentiation of human mesenchymal stem cell.