In this study, we investigated the effect of solid culture medium on the production of cordycepin in Cordyceps militaris. The regression equation was expressed as follows: Y1= 755.3-58.6625X1+4.79432E-14X2-46.6625X3-5.66269E-14X1X2- 0.025X1X3+1.62475E-14X2X3-160.6625X1 2+0.0125X2 2-206.9625X3 2, where, Y represents the value of cordycepin content (μg/g), X1 corresponds to the weight of M. alternatus in solid culture medium (g/bottle), X2 to the water content of the solid culture medium (%), and X3 to the culture period (day). The solid culture medium was optimized using the response surface methodology, and the optimal medium composition was as follows: the weight of M. alternatus in solid culture medium and water content were 16.2% and 100.7% (20.14 mL water/20 g solid culture medium), respectively, with a culture period of 39 days. Under these conditions, the cordycepin content of the fruiting bodies reached 150.0 μg/g (actual value). The supplementation of M. alternatus in solid culture for improved cordycepin content of C. militaris seems to be a promising alternative to wild and solid cultivation.

Periodontitis and periimplantitis are caused as a result of dental biofilm formation. This biofilm is composed of multiple species of pathogens. Therefore, controlling biofilm formation is critical for disease prevention. To inhibit biofilm formation, sugars can be used to interrupt lectin-involving interactions between bacteria or between bacteria and a host. In this study, we evaluated the effect of D-Arabinose on biofilm formation of putative periodontal pathogens as well as the quorum sensing activity and whole protein profiles of the pathogens. Crystal violet staining, confocal laser scanning microscopy, and scanning electron microscopy revealed that D-Arabinose inhibited biofilm formation of Porphyromonas gingivalis , Fusobacterium nucleatum , and Tannerella forsythia . D-Arabinose also significantly inhibited the activity of autoinducer 2 of F. nucleatum and the expression of representative bacterial virulence genes. Furthermore, D-Arabinose treatment altered the expression of some bacterial proteins. These results demonstrate that D-Arabinose can be used as an antibiofilm agent for the prevention of periodontal infections.

2D 퍼즐은 인기있는 보드게임이다. 2D 퍼즐을 완성하는 기술은 많이 연구되었다. 하지만 2D만으로는 대상 을 효과적으로 표현하기 어렵다는 한계가 있다. 본 연구에서는 영상으로부터 높이를 가진 2D+ 레고 퍼즐을 생성하는 방법을 제안한다. 이를 위해서 본 연구에서는 영상의 높이 맵과 분할 맵의 정보를 활용한다. 우리 는 2D+ 퍼즐에 적용하기위해 다양한 대상의 높이 및 영역 정보를 적절하게 처리해야한다. 이러한 이유로, 우리는 깊이 맵과 분할영역 맵을 추출하기 위해 모델에 심층 학습 모델을 적용한다. 높이 맵을 추출하기 위 해 우리는 CelebAMask-HQ dataset으로 학습한 BiseNet을 채택했다. 그리고 분할 맵을 얻기 위해 NYU Depth V2 dataset으로 학습한 DenseDepth를 사용했다. 입력 영상에 대해서 저해상도 영상 및 높이 맵과 분할 맵을 추출하고, 저해상도 영상을 레고 브릭의 색 팔레트를 적용한 영상에 대해서 높이 맵과 분할 맵 정보를 적용해서 높이를 가진 2D+ 픽셀 아트 영상을 생성한다. 그리고, 이 픽셀 아트 영상에 대해서 같은 높이와 같은 색을 가진 픽셀들에 대해서 최대한 큰 브릭을 적용하는 그리디 알고리즘을 적용해서 2D+ 레 고 퍼즐을 완성한다. 본 연구에서는 다양한 초상화를 대상으로 2D+ 레고 퍼즐을 완성하는 예를 제시하였으 며, 그 중 하나를 직접 제작하여 그 결과를 제시한다.

The Korean Air-Force aircraft maintenance depot paints the exterior of various aircraft, including high-tech fighters. Aircraft exterior painting is a maintenance process for long-term life management by preventing damage to the aircraft surface due to corrosion. The de-painting process is essential to ensure the quality of aircraft exterior paints. However, because the Korean Air-Force’s de-painting process is currently done with sanding or Plastic Media Blasting (PMB) method, it is exposed to harmful dust and harmful compounds and consumes a lot of manpower. This study compares the de-painting process currently applied by the ROK Air-Force and the more improved process of the US Air Force, and performs economic analysis for the introduction of advanced equipment. It aims to provide information that can determine the optimal time to introduce new facilities through Cost-Volume-Profit (CVP) analysis. As a result of the analysis, it was confirmed that the sanding method had the most economical efficiency up to 2 units per year, the PMB method from 3 to 21 units, and the laser method from 22 units or more. In addition, in a situation where the amount of de-painting work is expected to increase significantly due to the increase in fighters in future, BEP analysis was conducted on the expansion of the existing PMB method and the introduction of a new laser method. As a result of the analysis, it was confirmed that it is more economical to introduce the laser method when the amount of work exceeds the PMB work capacity(18 units per year). The paper would helpful to improve the productivity and quality of the Korean Air Force Aircraft maintenance depot through timely changes of facilities in the workplace in preparation for expansion.

본 연구의 목적은 한국 대학생들의 기초체력과 신체활동량이 폐기능과 상관관계가 있는지를 분석하고, 성별에 따른 차이를 검증하는데 있다. 건강한 참여자 312명(남성 150명[평균연령: 19.29±1.72세], 여성 160명[평균연령: 19.05±1.17세])은 신체조성, 기초체력, 신체활동량 설문지, 그리고 노력성폐활량 (FVC)과 1초간 강제호기량(FEV1)의 폐기능 검사를 수행하였다. 연구결과, 남학생의 폐기능은 우악력과 좌악력, 그리고 배근력과 관련이 있었고, 여학생의 폐기능은 모든 기초체력 하위 요인과 관련이 있었다. 또한 여성의 폐기능은 중강도 신체활동량과 관련이 있는 반면 남성의 폐기능은 신체활동량의 모든 하위 요인과 관련이 있었다. 본 연구의 주요 발견은 폐기능을 개선하기 위해서 남학생은 신체활동량을 증가시키고, 여학생은 기초체력을 향상시킬 필요가 있음을 제안한다. 대학생들의 폐기능을 유지하고 개선시키기 위해서는 폐기능 관련 인자에 대한 성별의 차이를 이해하고, 성별에 맞는 교육적 노력이 필요할 것이다.

The purpose of this study was to analyze changes to body measurements and silhouettes after wearing an early 19th century women’s corset. Two types of corsets were tested. Changes in body size and silhouette were compared based on the levels of tightening strength of the corset. The tightening strength was adjusted in 4 steps by making the length of back fastening string 10-40 cm shorter than the standard. The silhouette was compared with the front silhouette and the side silhouette. The results were as follows. After wearing the experimental 19th century corsets, the chest circumference and front interscye length increased. However, the chest circumference did not increase proportionally to the tightening strength. The underbust circumference, waist circumference, and back interscye length also decreased. The waist width was decreased to create a slim front silhouette. The change in the body silhouette differed depending on the style of the experimental corset. The experimental corset made with the six-piece torso pattern changed the posture so that the shoulders were pulled back and the chest was pushed forward. The experimental corset with the side bodice pattern resulted in the subject’s shoulders reclining backward and the chest and abdomen extending forward. The results of this study show that women’s body sizes and silhouettes could be changed by wearing the early 19th century corsets, but the changes in body size and silhouette vary depending on the wearer's individual body type or corset style.

In this study, the near-complete genome sequence of the novel reassortant H1N2 influenza A virus strain A/swine/Korea/KS60/2016 is reported. Sequences of the hemagglutinin (HA), neuraminidase (NA), and polymerase basic 2 (PB2) genes were analyzed, revealing that the isolates contain segments from previous Korean swine H1N2 strains. Additionally, the remaining genes of this strain originated from human H1N1 strains in 2009.

Roridin E, produced by Podostroma cornu-damae, is a mycotoxin with anticancer activity. To increase the content of roridin E, submerged culture conditions were optimized using response surface methodology. Three factors, namely, medium initial pH, incubation time and agitation speed were optimized using a Box–Behnken design. The optimum submerged culture conditions to increase the content of roridin E included a medium with an initial pH of 4.0, an incubation time of 12.90 days, and an agitation speed of 63.03 rpm. The roridin E content in the submerged culture, under the aforementioned conditions, was 40.26 mg/L. The findings of this study can help lower the current price of roridin E and promote its related research.