Objective : Liver cancer is common cancer generating 11.3% incidence in Korea. But Oriental medical doctor (OMD) often can't measure therapy on liver cancer positively because that the prognosis on it is not good. It is impossible the results on all of diseases not only liver cancer always to have to be good. Methods : It is studied the literature referencing liver cancer, experimental articles to insist the effects of Oriental medicine planet to liver cancer and the clinical cases on liver cancer to be treated as Oriental medicine therapy to have effects. Results : it is required to find out the causes of diseases and therapy method to conquest the diseases for the medical therapy. But because the results on medical therapy are not always good, it is necessary for the doctor who want to treat the diseases like liver cancer having the prognosis to be death to protect himself, like as the legal system, a medical policy. And consequently, this protecting legal system lead the medical therapy principle or method on some special diseases to therapy completion on it. As a results of policy, medical therapy have to be developed. Recently, there have been many other development in oriental medical therapy. This development can be grouped as two type. One type is clinical part and the other is experimental research part. Specially the experimental research and clinical research on live cancer in oriental medical therapy have been developed. So the present day is the time to make medical policy on liver cancer for OMD to measure oriental medical therapy and develop oriental medical theory. Conclusions : As a above results, we propose that the name of liver cancer have to use in Korean medicine security clinical name (한방의료보험상병명) to make oriental medical policy.

Atrial natriuretic peptide (ANP), a circulating peptide hormone with 28 amino acids secreted from cardiac atria, plays an important role in the maintenance of fluid and electrolytes homeostasis. The actions of ANP appear to be mediated by specific receptors on target cells. However, the specific antagonist for ANP receptors is not yet to be defined. The present study was undertaken to evaluate the antagonistic effects of water extract obtained from the gardenia (Gardenia jasminoides Ellis) on the natriuretic peptide receptor system in the kidney. In the kidney of Sprague Dawley rats, specific 125I-ANP binding sites were localized in glomerulus, inner medulla, intrarenal artery, and vasa recta bundle by using quantitative in vitro receptor autoradiography. These specific bindings were competitively displaced in a dose dependent manner by water extract obtained from the gardenia. Moreover, productions of 3',5'-cyclic guanosine monophosphate (cGMP) via activation of particulate guanylyl cyclase (GC) by ANP were increased in receptor proteins from the glomerulus and inner medulla of rat kidney. These cGMP productions were inhibited in a dose dependent manner by water extract obtained from the gardenia. The inhibitory effect of water extract obtained from the gardenia on activation of GC was quantitatively more potent rather than on 125I-ANP bindings to these renal structures. From affinity cross-linking study on the specific receptor proteins, the water extract obtained from the gardenia inhibited the 125I-ANP labeling of GC-coupled natriuretic peptide receptor from renal glomerulus of rat. Intravenous infusion of ANP elicits the potent diuresis, increment of urine osmolariry, and excretions of urinary chloride, creatinine and PAH in New Zealand White rabbit. These renal effects of ANP were inhibited by the intravenous pre-treatment of water extract obtained from the gardenia without changes in systemic hemodynamics including mean arterial blood pressure and heart rate. These results indicate that the water extract obtained from the gardenia may could be block the GC-coupled natriuretic peptide receptor, and suggest that the extract may contain a natural antagonistic molecule regulating the renal natriuretic peptide system.

The present study was undertaken to evaluate the antagonistic effects of water extracts of Chinese gooseberry (Actinidia chinensis P.) root on the natriuretic peptide receptor system in the rat kidney. By using in vitro receptor autoradiography, specific 125I-atrial natriuretic peptide (125I-ANP) binding sites were localized in glomerulus, inner medulla, intrarenal artery, vasa recta bundle, and renal pelvis of Sprague Dawley rat kidney. These specific bindings were competitively displaced by water extracts of Chinese gooseberry root in a dose dependent manner. Also, productions of 3',5'-cyclic guanosine monophosphate (cGMP) by activation of particulate guanylyl cyclase (GC) were stimulated by ANP in the glomerular and inner medullary membranes from rat kidney. These cGMP productions were inhibited by water extracts of Chinese gooseberry root in a dose dependent manner. The inhibitory effect of water extracts of Chinese gooseberry root on activation of GC was more potent rather than on 125I-ANP bindings to these renal structures. From affinity cross-linking study, the water extracts of Chinese gooseberry root inhibited the 125I-ANP labeling of GC-coupled natriuretic peptide receptor from renal glomerulus. Intravenous infusion of ANP elicits a potent diuresis, and urinary sodium and chloride excretions in New Zealand White rabbit. The pre-treatment of intravenous water extracts of Chinese gooseberry root infusion decreased competitively various renal effects of ANP with out changes in systemic hemodynamics. These results indicate that the water extracts of Chinese gooseberry root specifically inhibits the GC-coupled natriuretic peptide receptor subtypes (NPR-A), and suggest that the water extracts of Chinese gooseberry root may contain an antagonistic molecule regulating the biological functions of ANP system in the kidney and other organs.

The six kinds of natural factors(It refers to wind, cold, summer-heat, dampness, dryness and fire.) is constantly moving to maintain the balance of whole climate of one year. Four seasons are the largest mediation of whole climate of one year. The cold and the heat have the relationship of mutual intervention. The dampness and the dryness have it also. In this process they raise various climate appearance. And that various climate appearance influence the whole lives on the earth. This paper is concerned with the classification of them.

Five elements motion and six kinds of natural factors influence not only human disease but also difference of medicine effect. Because the climate of summer is very hot, that is easy to increase the properties of hot medicines, a doctor must be careful to use it in summer. Also the climate of winter is very cold, that is easy to increase the properties of cold medicines, a doctor must be careful to use it in winter. But in the certain conditions to use diaphoretics or purgatives, in spite of that regulation a doctor can use them.

A Study on the Youkjoron(逆調論) of the So Moon(素問) one of the classic book of oriental medicine, was carried out analytically for the right comments. The principal ideas abtained summerized as follows: The unbalance between Eum(陰) and Yang(陽) The unbalance between Su(水) and Wha(火) The Yuk Ga(肉苛) which is caused by the unbalance of the Young Wi(營衛) The Asthma(喘息) which is caused by the unbalance of the Viscera(臟腑)

A study on the Byungtae Ron(病能論) of the So Moon(素問), one of the classic book of oriental medicine, was carried out analytically for the right comments. The principal ideas obtained summarized as follows; Neng(能) is similar to tae(態) in the pronunciation and the meaning of a chinese character. Byungtae(病能) means the state of the symptoms and the pulse condition of the diseases, etc. It deals with ethological factor, mechanism of disease, the condition of an illness, method of diagnosis, rule of treatment, technique of treatment of seven diseases and taking this seven diseases as a example, mainly discuss the technique and significance of clinical observation and the pathogenesis and condition of an illness, so It named Byungtaeron(病能論) In this chapter it shows we can grasp condition of illness well only if we classify the pathogenesis and condition of an illness in details. this viewpoint provides the foundation of development in oriental diagnostics. It places emphasis on pulse feeling in this chapter, so it describes pulse condition of various kinds of diseases in details. It also presents how to compare pulse feeling like comparison between Inyoungmaek(人迎脈, arterial carotid communes, the pulsation of which is easily felt beside Adam's apple) and Ch'onkumaek(寸口脈, the radial artery on the wrist where the pulse is routinely taken for diagnosis), between right and left Ch'onkumaek(寸口脈), between Yangmyungsangdong (陽明常動) and Taeyangbudong(太陽不動), Soyangbudong(少陽不動), etc. In this chapter it explains pulse feeling occupies a high position in the diagnosis of diseases in Huangdi's internal Classic(黃帝內經) period and the technique of pulse feeling is already plentiful and minute. In this chapter it presents Tongbyungyichi(同病異治, to apply different methods of treatment to the same kind of disease) theory, taking tangible syndromes as examples. this is prominent viewpoint of determination of treatment based on the differentiation of symptoms and signs and much influence development of later ages' medicine. On the ground of oriental medical theory, it may bring about different symptoms in the same disease according to stage of disease, the seasons, the regions, the constitution of patient, therefore surely adopt different technique of treatment. this differentiation of symptoms and signs is an important character in oriental medicine.

Iridology, developed more than 100 years ago, is the diagnosis of medical conditions through noting irregularities of the pigmentation in the iris The purpose of this study is to compare interrelation between CVA, hypertension family history and cardio-renal connective tissue in Iris Constitution through iris constitution examination. The subjects consist of 114 patients who were examined in Iris Constitution at Chonju Oriental Medicine Hospital attached to Wonkwang Univ. from September. 1st. 2000 to August. 31th. 2002. 1. In the distribution of Iris Constitution, among of 79cases, There are neurogenic type 13cases, abdominal connective tissue weakness constitution 31 cases, cardio-renal connective tissue weakness constitution 6 cases, cholesterol 7 cases and others 22 case in control group. 2. There are familial history of CVA and hypertention 32 cases, no familial history of CVA and hypertention1 3 cases, in 35cases of experimental group. These results imply that there is meaningfulness of interrelation between cardio-renal connective tissue weakness constitution and CVA, hypertention.

本篇靈樞․腸胃는 인체의 소화기에 길이와 용적에 대한 고대인들의 인식이 포함되어 있어 이를 통해 그들의 해부학적인 인식의 수준과 內經의 여러 편에 나오는 당시의 도량형에 대한 이해를 도울 수 있다. 이 편을 연구한 결과 다음과 같은 결론을 얻었다. 1. 靈樞․腸胃에서 제시한 소화관의 총길이(6丈4寸4分)와 현대해부학에서 제시한 소화관의 평균길이(9m)를 비교할 때 本篇에서 사용된 寸의 개념은 약 1.5cm로 볼 수 있으며 또한 가장 근사하게 일

A study on the Pyo Bon Byung Jeon Ron(標本病傳論) of the So Moon(素問), one of the classic book of oriental medicine, was carried out analytically for the right comments. The principal ideas obtained summarized as follows; There are two important contents in this volume. First, disease shows primary and secondary symptoms, and there is an obey way or disobey way to heal it. Second, disease can transfer to the other part. When people are attacked with a disease, it spreads in principal way in our physical. The main substance that we mentioned are in first and second. Since this volume deals with a primary and secondary symptoms and a transfer disease. We called it Pyo Bon Byung Jeon Ron(標本病傳論).

Being based on oriental medicine, the body intimates with the mind. Therefore vitality attachs to heart, will attachs to spleen, purpose attachs to kidney and spirit attachs to lung. The mind is very important cause of a disease. Bonsin means the five viscera vitality. The acupuncture of the beginning always depend of vitality, therefore the name of this volume is BonSin. This volume explains the mind activity of human body that is vitality, essence of life, soul, spirit, feeling, will, purpose, wisdom and thought. In addition explains that's origin and the connection of the mind and care. A disease appears on the occasion of nerve strain, so we observe a mental state in case of treatment. This volume divide in three chapters. ChapterⅠ deals with the meaning of consciousness and connection with the cause of a disease. ChapterⅡ deals with an illness of five hollow organs's consiousness and the time of death for it's results. ChapterⅢ deals with the deficiency and exceess of a mental disease and mind-culture.

Weigi(衛氣) is defensive energy which moves outside the conduits, permeating the surface of the body and warding off exogenous pathogens ; superficial resistance of the body. Yinggi(營氣) is constructive energy which moves though the conduits and nourishes all the organs This volume commets on creation and gathering of Yinggi(營氣)-Weigi(衛氣). Therefore subjicts can be chosen Yong Wi Sang Whei(營衛生會). This volume contents three chapters ChapterⅠdeals that yingi(營氣) is created from zhuogi(終期) ; dense part of food essence or waste gas, e.g., the air expirde or flactus discharged; and wei is created from qinggi(淸氣); ⑴ fresh air usually referred to the air inspired in the lung ⑵ food energy or nutrient esp. the clarified thin part of food essence ⑶ clear up the evil heat from the Qi system: a method in treating febrile diseases. Chapter Ⅱ deals with the difference between a youth and adult. Chapter Ⅲ deals with the relation between yinwei(영위) and Triple Burners.

The contents of Yuk Won Jung Gi Dea Ron(六元正紀大論) are explained on the basis of the so-called theory “he Five Circuit Phases and the Six Atmospheric Influences theory (五運六氣論).” Yuk Won(六元) means six atomspheric influences that are wind, cold, heat, damp, dryness, fire. Jung Gi(正紀) means normalcy of movement. Therefore this volume is so called This volume contents seven chapters. ChaterⅠ takes charge of the year's GiGi(地支) for understanding the five circuit phases and the six atmospheric influences. ChaterⅡ deals with the year of TaiYangHanSue(太陽寒水) that is third atmospheric influences and operating state of Six Atmospheric Influences. ChaterⅢ deals with the year of YangMingZaoJin(陽明燥金) that is third atmospheric influences and operating state of Six Atmospheric Influences. ChaterⅣ deals with the year of ShaoYangXiangHuo(少陽相火) that is third atmospheric influences and operating state of Six Atmospheric Influences. ChaterⅤ deals with the year of TaiYinShiTu(太陰濕土) that is third atmospheric influences and operating state of Six Atmospheric Influences. ChaterⅥ deals with the year of ShaoYinJunHuo(少陰君火) that is third atmospheric influences and operating state of Six Atmospheric Influences. ChaterⅦ deals with the year of JueYinFengMu(厥陰風木) that is third atmospheric influences and operating state of Six Atmospheric Influences.

This fasciale, a remainder of So Moon(素問) with Bon Byung Ron(本病論), is a part of the theory of the Five Circuit Phases and the Six Atmospheric Influences(五運六氣學) that studied and discussed the rules of the weather change in ancient oriental medicine. The change in weather is one of the most important factors which influence man's health therefore the theory is worth while to study further. This fascicle explains the cause of diseases occured by irregular and exceptional change of weather and acupunctural treatment methods to prevent and cure those kinds of disease as its title -Ja Bup Ron(刺法論)-suggests. During Tang Dynasty(唐) when Wang Ping(王氷) commentated the So Moon(素問) only the title of this fascicle was kept but the contents of it was lost differing from Seven volumes of the Five Circuit Phases and the Six Atmospheric Influences(運氣七篇). However in the times of the North Song Dynasty(北宋) when Kao Pao-Heng(高保衡), Lin I(林億) and the other scholars studied and compared medical books this fasciale and another lost fasciale-Bon Byung Ron(本病論) appeared with theirs notes. So these two fascicles called Lost Volumes of So Moon(素問遺篇). But we can infer these two fascicles were written by a certain Taoist during the ninth and tenth century A.D. - the former times of Kao Pao-Heng(高保衡), Lin I(林億) and the other scholars studied and compared medical books during the North Song Dynasty(北宋) since Wang Ping(王氷) because this fascicle connots the Taoism training methods such as Pe Gi(閉氣), Jon Sang Bup(存想法) and Oi Dan Bup(外丹法) and so on. This thesis runs as follows; Chapter 1 deals with acupuncture treatment to prevent and cure Ul(鬱) disease occuerd by Sung Gi Bu Jun(升之不前) of the Six Atmospheric Influence(六氣). Chapter 2 deals with acupuncture treatment to prevent and cure diseases due to Bul Chun Jung(不遷正) and Bul Toi Wui(不退位) of the Six Atmospheric Influence(六氣). Chapter 3 deals with acupuncture treatment of an epidermic(疫癘) due to the deviation of the Five Ciecuit Phases from the regularity(五運失守). Chapter 4 deals with the symptomes of an epidemi and the preventive treatments such as Jon Sang Bup(存想法), Vomitory treatment(吐法), respiratory treatment(汗法) and So Kum Dan Bang(小金丹方). Chapter 5 deals with the interaction among the five viscera and the six bowels as well as the principle of the acupuncture.

This part comments the part related to filiform needle(小鍼) among the contents of Ku Chim Sip I Won(九鍼十二原) in Young Chu(靈樞) Ku Chim Sip I Won explains ① the name, the form and the use of nine kinds of neddles, ② and reinforcement and reduction through inserting the neddle in the same direction as the channels runs or in the opposite direction, and closing or enlarging the acupuncture hole etc., ③ and notice and contraindication in applying acupuncture, ④ and the close relationship of between diagnosis and acupuncture, ⑤ and the adverse reaction through a wrong treatment. Thus, it is very important to studying this part which comments Ku Chim Sip I Won. Summerizing the contents of the "So Chim Hae(小鍼解)" in reference to the contents of Ku Chim Sip I Won. the contents were as follows; What attracts our attention in chapter Ⅰ is the basic principles of applying acupuncture. What attracts our attention in chapter Ⅱ is reinforcement and reduction based on shortage and surplus, and their related reactions of human body. What attracts our attention in chapter Ⅲ is dividing the invasion of pathologic factors into three category(upper, medium, lower part) and then its mechanism and therapy, and the adverse effects through wrong treatmant. What attracts our attention in chapter Ⅳ is explaining the importance of observation of complexion and paltation of abdomen. Chim Hae(鍼解) in So Moon(素問) also comments Ku Chim Sip I Won in the same way that this part does, and yet there are not a few differences from this part in noting. Thus we need the comparative study of between this part and Chim Hae to understand Ku Chim Sip I Won. Besides we have to add the comparative study of views of distinguished physicians to correctly understand. I therefore made a comparative study both on the contents of those parts related to this part,and on the commentations of distinguished physicians to correctly understand Ku Chim Sip I Won, the important part about acupuncture.

This fascicle is named as Si Jong Yong Ron because it puts an emphasis on attitude in diagnosis and is divided into two chapters, chapter 1 dealing with the principle of how to distinguish differences and how to compare similarities in classification, chapter 2 emphasizing an importance in classification alike examplfying similar symptoms of diseases in spleen, stomach, and lung. Accurate diagnosis should be at first done for proper treatment, classification should be accurate for precise diagnosis, and calm and intensive observation to a patient could give rise to precise classification. This fascicle has a great significance in that it supplies a detailed explanation about the principle for precise classifiication.

The contents of Han Yul Byung (寒熱病) are explained on the basis of the so-called theory "Yin and Yang, the Five Evolutive Phases (음양오행)" ; The text of the Han Yul Byung (寒熱病) of the Young Chu (靈樞) was written in the Kap Ul Kyung (甲乙經) chapter 5, 7, 8, 10, 11 and 12 ; Also it was written in the Tae So (太素) volume 10 and 26 ; Also it was introduced in the Ryu Kyung (類經) volume 20, 21 and 22 by Jang Kae-Pin (張介賓) in the Myung (明) dynasty ; Summarizing the contents of the Han Yul Byung in reference to the contents of successive generation note, the contents run as follows: Chapter 1 deals with the symptoms and treatment of diseases which accompany chills and fever (寒熱病) ; Chapter 2 deals with arthralgia with other joint systems (骨痺) and flaccid paralysis of limbs (體惰病) ; Chapter 3 deals with indications of five points around the Chen You Points (天牖穴) Chapter 4 deals with the treatment of toothache ; Chapter 5 deals with the treatment of headache and eye pain ; Chapter 6 deals with the acupuncture manipulation according to changes of season ; Chapter 7 deals with the serious influence of carbuncle according to the region of body ; Chapter 8 deals with the treatment of heat-syndrome ; Chapter 9 deals with the side effect of acupuncture ; It is too difficult to understand the Han Yul Byung (寒熱病) , because it is written in old chinese ; Consequence of above reason, the writer of this article has researched to find out the exact meaning of that ; 