코로나바이러스감영증-19 사태가 전세계를 강타하면서, 우리는 기존과 다르게 변해가는 일상 에 적응하는 뉴노멀 시대를 맞이 하였다. 코로나19 이후, 방송, 강의분야 등 문화예술계에도 비대면 문화가 급속도로 확산되고, 방송업계는 랜선방청제도를 도입하여 화상시스템을 통한 온 라인 실시간 방청을 제공하여 관객의 참여를 유도하고 있으며, 강의행사 분야도 화상회의 시 스템을 활용한 진행과 유튜브 플랫폼을 활용한 실시간 송출의 비대면 형태로 진행되고 있다. 이러한 비대면 참여환경은 물리적 스테이지의 한계, 음향 촬영 구도의 아쉬움, 현장감, 생동감 등 몰입적 측면에서의 한계가 존재하고, 언택트 방송 및 공연의 경우 음향과 촬영구도가 아쉬 운 부분으로 꼽히며 현장과의 괴리감, 집중하고 싶은 장면을 선택하여 볼수 없다는 한계도 지 닌다. 비대면 강의 경우에도 일상에서 쉼 없이 이어지는 비대면 참여 환경에 ZOOM Fatigue 라는 신조어가 등장할 만큼 비대면 환경에서의 집중력과 흥미를 잃어가는 현상이 나타나고 있 다. 이처럼 코로나19로 인한 변화가 일상화되면서 인류의 역사는 코로나19 (BC, Before Corona), (AC, After Corona) 나뉠 것이라는 예측이 일기도 한다. 무엇보다 코로나19로 인 해 인류의 정치, 경제, 사회, 문화, 교육등 모든 영역이 대변화를 맞은 가운데 가장 큰 변화는 물리적 접촉이 최소화되면서 Untact문화가 확산됐다는 점이다.

문화유산은 조상들의 문화중에서 후손들에게 물려줄 만한 가치가 있는 것을 말한다.[1] 우리의 문화유산을 우리의 역사, 정체성, 그리고 자부심을 담고 있으며, 이를 통해 우리는 과거의 삶 과 지식, 그리고 경험을 재조명하고 이해할 수 있다. 우리의 문화유산을 보전하고 전파하는 것 은 매우 중요하다. 이를 위해 우리는 문화콘텐츠와 IT기술의 융합적인 미디어아트를 활용하여 이를 알리고자 한다. 이러한 미디어 아트는 국내외 관광객들에게 우리의 문화유산을 소개하는 데 더욱 효과적이다. 전남의 3대 별서정원은 이러한 문화유산 전파의 중요한 장소로서, 다양한 콘텐츠를 통해 우리의 문화유산을 소개하고 있다. 이를 다중디스플레이를 활용한 문화관광 콘 텐츠로 더욱 널리 알리고 우리문화의 보존과 계승에 크게 기여한다.

The effect of the ionization energy on the common house mosquito, Culex pipiens, pupa was investigated as the hatching rate, longevity and detoxification enzyme activity. The longevity of adult emerging in the pupa decreased depending on the exposure dose of Gray (Gy) in Cx. pipiens. The hatching rate of the F1 generation egg derived from Cx. pipiens pupa treated up to 70 Gy did not show any difference with the control, but the eggs did not hatch 100% at 120 Gy exposure. These results showed that Cx. pipiens was sterilized at 120 Gy. Several detoxifying enzyme (GST, non-specific esterase and MFO) activity of Cx. pipiens adult emerged from pupa irradiated with 120 Gy was investigated. The difference in activity was observed in female than in male irradiated with electron beam. As a result, electron beam irradiation seems to affect enzyme activity as well as induce infertility of Cx. pipiens.

The diamondback moth (DBM), Plutella xylostella, is a globally distributed and important economic pest. Chemical control is the primary approach to regulate populations of this pest. Chlorantraniliprole is the first commercial insecticide that belongs to the new chemical class of diamide insecticides. In this study, the resistant strain was observed 1578-fold resistance to chlorantraniliprole. Point mutation (G4946E) in ryanodine receptor (RyR) showed a high frequency. Enzyme assays indicated that glutathione S-transferase (GST) activity in the resistant strain was 2.4 times higher compared with the susceptible strain, whereas no difference was seen for P450 and esterase. In addition, the expression of two GSTs genes was up-regulated. These findings pave the way for the complete understanding of the mechanisms of diamide insecticides resistance in insects.

Zika virus has become a problem in the world recently. Zika virus is spread by several different species of Aedes mosquitoes, Aedes albopictus is one of them. The Asian tiger mosquito, Ae. albopictus, is already inhabit the Korea. Therefore, control of this mosquito is very important and urgently needed. Environmental friendly control methods to a change in the recognition of people have been desired. Essential oils and plant extracts may use an alternative method to control the mosquitoes. This study describes about the insecticidal and repellent against Ae. albopictus using plant materials.

The insecticidal activities of materialsderived from Dryopteris crassirhizoma Nakai against third instar larvae of three species mosquitoes (Culex pipiens, Aedes albopictus and Anopheles sinnensis) were evaluated using a direct contact mortality bioassay. The methanol extracts of D. crassirhizoma showed 100%, 87.8% and 100% larvicidal activity at 1,000 ppm against Cx. pipiens, Ae. albopictus and An. sinensis, respectively. Hexane fraction showed 100% larvicidal activity three species mosquitoes at 500 ppm after 24 hrs. Purification of the biologically active constituents from the hexane extraction with larvicidal activity was done using silica gel column chromatography. H1 and H3 fractions gave 100% mortality to Cx. pipiens, Ae. albopictus and An. sinensis at 100 ppm. H1 fraction separated with methanol to give a H111 through centrifugation. Fraction of the biologically active constituents from the H3 fraction with larvicidal activity was done using methanol. H31 fraction was determined 100% mortality to Cx. Pipiens, Ae. albopictus and An. sinensis at 50 ppm, respectively. Two fractions were analyzed C14H22O (H111, MW206.0) and C11H14O4 (H31, MW210.08) by GC and GC-MS. D. crassirhizoma derived compounds described herein could be useful for managing filed populations as larvicide of Cx. pipiens, Ae. albopictus and An. sinensis.

Monochamus saltuarius, which mediates Bursaphelenchus xylophilus is one of the important vector of pine wilt disease recently. M. saltuarius showed difference with weight, growth, and oviposition according to species of trees. The most feeding amount and feeding area were determined in P. koraiensis. However, M. saltuarius almost did not feed and longevity was observed very short time only for 10 day in Sciadopitys verticillata. Weight, length and head width were measured the highest growth of M. saltuarius in P. koraiensis. Female of M. saltuarius was determined more growing than male of M. saltuarius in all species of trees. Tree preference for oviposition of M. saltuarius was the highest choice in P. densiflora. However, lots of scar for oviposition have observed but M. saltuarius laid less eggs in P. rigida. This result is related to bark thickness of trees. Ovipositional frequency has been consistently maintained to P. densiflora and P. koraiensis at 20 day intervals. In this study, physiological and ecological characteristic of M. saltuarius to preference of trees were researched could be helpful for managing of M. saltuarius.

The purpose of this study is to analyze the correlation between the stature and the muscle performance ratings and the subjective discomfort rations at performing lower arm's pronation and supination according to change sin the height of working table for more efficient performance at designing a working table and performing a work. For the purpose, this study conducted an experiment targeting 40 people in their 20s, who were classified into 4 groups each group composing 10 people at intervals of 5cm from the standard stature of 166.5cm. The experiment measured the maximum isometric pronation and the supination muscular power, and at measuring the factors, the heights of working tables were set as 800mm, 850mm, and 900mm. From the measurement results, it was found that the stature and the maximum muscular power was correlated. That is, as the experiment groups's average stature is higher, the maximum muscular power was higher. For the correlation between the motion patterns(pronation and supination) and the maximum muscular power, it was seen that the maximum muscular power was higher at performing the pronation than the supination. In the correlation between motion patterns and the subjective discomfort ratings, it was seen that the subjective discomfort rating was higher at performing the supination than the pronation. For the correlation between height adjustment and the subjective discomfort ratings, as the height of working table was lower, the subject discomfort rating was lower. Therefore there was no difference in the maximum muscular power according to the height changes of working table, but it was found that as the working table was higher, the user felt more comfortable.

Field-collected populations of mayflies, Ephemera orientalis were tested for susceptibility to 10 different insecticides using a direct-contact mortality bioassay. Ephemera orientalis subimagoes were susceptible to the insecticides chlorpyrifos, fenitrothion and chlorfenapyr with LD50 values of 69.7, 78.8 and 81.9μg/♀, and adults had LD50 values of 71.9, 78.8 and 85.4μg/♀, respectively. Susceptibility ratios(SRs) of subimagoes and adults of E. orientalis to the 10 insecticides were 1.0 to1.2 folds. The mayflies showed higher susceptibility to organophosphates than to pyrethroids. The SRs of Anopheles sinensis to E. orientalis were 514 to 1,438 fold higher for organophosphates (LD50 values of 0.05 to 0.23μg/♀) and 62 to 1,155 fold higher forpyrethroids (LD50 values of 0.13 to 2.41μg/♀). The SRs of Culex pipiens to E. orientalis were 606 to 3,595 fold higher for organophosphates with LD50 values of 0.02-0.17μg/♀ and 81 to 1,365 fold higher for pyrethroids with LD50 values of 0.11- 1.83μg/♀. These results indicate that the use of ineffective insecticides will result in unsatisfactory control against field populations of the subimagoes and adults of E. orientalis. This work was supported by a research grant from the National Vector Control and Surveillance work performed by the Korean National Institute of Health.

In using both hands, everyone dominantly use one hand and it is called left-handedness or right-handedness person. Measurements of grip and pinch strength provide objective indexes to represent functional integrity of the upper extremity. This study was conducted for thirty female college students(19 right-handedness and 11 lefthandedness). For assessment of the type of handedness, questionnaire was used; for grip strength, Jamar dynamometer was used; for pinch strength, Jamar pinch gauge was used. In right handedness, the grip and pinch strength of the dominant right hand was significantly higher than those of the non-dominant hand. In addition, regular exercises were shown to give influences on reduction of strength gaps between dominant and non-dominant hands. In both groups of left and right handedness, the grip and pinch strength of the dominant hand were significantly higher than those of the non-dominant hand, and regular exercises were shown to give influences on reduction of strength gaps between dominant and non-dominant hand.

We have investigated the optical properties of the global haze on Titan from spectra recorded between 7100 and 9200Åwhere CH4 absorption bands of various intensities occur. The Titan spectra were obtained on Feb. 23, 2005 (UT), near the times of the Cassini T3 flyby and Huygens probe, using an optical echelle spectrograph (BOES) on the 1.8-m telescope at Bohyunsan Observatory in Korea. In order to derive the optical properties of the haze as a function of altitude, we developed an inversion radiative-transfer program using an atmospheric model of Titan and laboratory CH4 absorption coefficients available from the literature. The derived extinction coefficients of the haze increase toward the surface, and the coefficients at shorter wavelengths are greater than those at longer wavelengths for the 30 - 120 km altitude range, indicating that the Titanian haze becomes optically thin toward the longer wavelength range. Total optical depths of the haze are estimated to be 1.4 and 1.2 for the 7270 -7360Åand 8940 -9150Å ranges, respectively. Based on the Huygens/DISR data set, Tomasko et al. (2005) reported total optical depths of 2.5 - 3.5 at 8290Å depending on the assumed fractal aggregate particle model. The total optical depths based on our results are smaller than those of Tomasko et al., but they partially overlap with their results if we consider a large uncertainty from possible variations of the CH4 mixing ratio over Titan's disk. We also derived the single scattering albedo of the haze particles as a function of altitude: it is less than 0.5 at altitudes higher than ~150Km the average particle radius is smaller than the wavelengths, whereas near the surface, it becomes comparable or greater.

Al t hough substance P(SP) , a potent pro- inflammatory peptide, is involved in inflammation and immune responses‘ t he eff'ect of SP on t he expression of macrophage inflammatory protein 3a (MIP- 3α CCL20) in periodontal liga ment(PDL) cell s a re unknown, Equally as enigmatic is the link between SP, t he stress protein heme oxygenase- l(HO-l) ‘ and CCL20 procluction, We investigated whether SP induces the release of chemokine CCL20 from immortal ized PDL(IPDL) ceJJ s‘ and fur ther c l a꺼 SP mediated pathways, We also examined the relationship between HO-l a ncl CCL20 by t reating PDL cells with SP, Incubating IPDL cells with SP increased expression of CCL20 mRNA a nd CCL20 protein in a dose-time dependent manner Highly selective p38 and ERKl/2 inhibitors abrogated SP-induced expression of CCL20 in IPDL cell s, SP is a lso responsible for ini t iating phosphorylation of I/C B, degradation of Iκ B‘ ancl activat ion of NF'-/C B, SP induced expression of HO-l in both a concentration- and time-dependent man nel ‘ and CCL20 refl ected s imilar patterns, The inductive effects o[ SP on HO- l and CCL20 wer e enhanced by HO- j inducer hemin and the membrane-permeable cGMP analog 8-bromo-cGMP, Conversely, this pathway was inJübited by t he 1-10난 inhi bitor zinc protoporphyrin IX(ZnPP IX) and the selective inl뼈itor of guanylate cyc1ase‘ lH-[l , 2, 4Joxad iazole[4‘ 3-aJquinoxal in-l-one (ODQ) , We report herein the pathway that connects SP along with other modulators 。f neuroimmunoregulationto the induction of HO-l and t he inflammatory mediator MIP-3a /CCL20 in IPDL cell s‘ which play an important role in the development 01' periodontitis or inflamrnation during orthodontic tooth movem

Interlellkin • 8(IL-8) is an important cytokine involved in tllmor growth and angiogenesis in a variety of malig nancies. bllt the regll lation of IL-8 in 01 외 cancer cells are llnderstood . We invesLigated whether mi togen-activated protein kinases pathway is involved in iron chelator-mediated lL-8 produdion in inunortalized and malignant oral keratinocytes. In this study we examined the role of p38 and extracellular signal- reglllated kinase• 1/2 in the expression of [L-8 by DFO. Incllbation of IHOK and HN12 cel ls with DF'O increased the expression of 11-8 mRNA. as well as the release of IL-8 protein. The signal transdllction study revealed that both p38 and ERK1/2 were significantly activated in response to DFO. Accord ingly. the selective inhibitors for both kinases‘ eit her a lone or combination. abolished DFO- induced lL-8 secretion. indicating an importance of MAP kinase pathway. Interestingly. however‘ inhibition of the p38 and ERK pathway more attenuated IL-8 secretion in IHOK than in HN12 cells. DFO induced NF-kB activation , suggesting a NF-kB- dependent mechanism in DFO- induced IL-8 production. In addition, p38 and ERK inhi bition resulted in the accelerated degradation of lL-8 mRNA, suggesting that in IHOK and HN12 cells, p38 and ERK cunLr iullLe Lo DFO imluced IL-8 secretion by IHOK and HN12 cells via a posttranscriptional mechanism that involves stabilization 01' the IL-8 transcript. Finally. we investigatecl llsing specific inhibitors : 8NP and G8NO for NO c1onor. PDTC for potent inhibitor of NF-kB. Cycloheximide for inhibition of de novo protein synthesis. We observecl 8NP ancl PD1'C clepenclent IL-8 gene incluction in IHOK cell s. but not in HN12 cells used specific inhibitors‘ Collectively. these results demonstrate that‘ targeting MAP kinase ancl NF-kB pathway may be a potentiaI approacb to controlling the angiogenes is ancl growth 이 human oral cancers

Background : Some of invasive plants, which were introduced from foreign countries, have caused problems in Korea. Invasion of these invasive plants in the ecosystem threatens the habitat of endemic species, reducing biodiversity, and causing a disturbance in the ecological system. Hypochaeris radicata L. (Asteraceae), the most invasive plants in Korea, particularly in Jeju Island, invade farmland, and autochthonous forest, establishing monocultures and modifying the ecosystem structure. This invasive species has become a serious environmental problem because they displace the indigenous plant species. This study was conducted to evaluate the antioxidantive effects of ethanolic extracts from different parts (root, stem, seed and leaf) of the invasive exotic species Hypochaeris radicata L. Methods and Results : The aim of present study was to estimate the total phenolic and flavonoid contents and to investigate in vitro antioxidant potential of ethanolic leaf, root, seed, and stem extracts of the Hypochaeris radicata. Antioxidant activity was assessed by using 2,2-diphenyl-1-picryl-hydrazyl (DPPH) assay, reducing power activity, [2,2-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid)] ABTS+ assay and ferrous ion chelating activity. The total phenolic and flavonoid contents were also determined and expressed in gallic acid and quercetin equivalent respectively. The results of the study indicate that the ethanolic extracts of the leaf, root, seed, and stem of H. radicata posses significant scavenging activity against DPPH (21.25% for leaf, 34.98% for root, 60.76% for seed and 45.25% for stem at 250 μg/ml each) and ABTS+ radical scavenging activity (14.85% for leaf, 17.40% for root, 35.91% for seed and 24.70% for stem at 250 μg/ml each), reducing power activity (0.178 absorbance at 300 μg/ml for leaf, 0.211 absorbance at 300 μg/ml for root, 0.447 absorbance at 300 μg/ml for seed, 0.276 absorbance at 300 μg/ml for stem). The free radical scavenging and antioxidant activities may be attributed to the presence of adequate phenolic (gallic acid content is 361.92.98 μg/g in leaf, 356.59μg/g in root, 719.72 μg/g in seed and 512.08 μg/g stem) and flavonoid compounds (219.52 μg/g in leaf, 75.67μg/g in root, 281.39 μg/g in seed and 215.66 μg/g stem). This study revealed that the ethanolic extracts of both leaf, root, seed and stem of H. radicata has demonstrated significant antioxidant activity. Conclusion : In conclusion, the present study has demonstrated that Hypochaeris radicata seed ethanol extracts are rich in phenolics and have a strong antioxidant activity and a radical-scavenging action in all of the tested methods. This suggests that Hypochaeris radicata is a good source of natural antioxidants.