Paradental cysts characteristically develop adjacent to the cervical margin on the lateral aspect of a tooth root and result from inflammatory processes within the periodontal pocket. Standard management usually involves cyst enucleation while striving to retain the affected tooth. Recurrence rates are infrequent following complete removal of the lesion. However, intentional replantation becomes necessary in cases with anatomical constraints or accessibility issues. We present the case of a 13-year-old female patient exhibiting delayed eruption of the mandibular left second molar, attributed to a cystic lesion located on the lingual-coronal aspect of the tooth.

본 논문에서는 지오폴리머의 상변화를 관찰하기 위하여 나노인덴테이션 데이터를 가우시안 믹스쳐 모델로 분석하는 방법을 제시 하였다. 지오폴리머는 일반 시멘트 대비 CO2 발생량을 줄일 수 있어 시멘트 대체 재료로써 많은 연구가 이루어지고 있다. 기존 연구들 로부터 최적의 실리콘/알루미늄 비율을 찾았으나 1.8 초과에서 압축강도 저하의 원인은 아직 불분명하다. 본 연구에서는 실리콘/알루 미늄 비율이 재료에 미치는 영향을 조사하고자 나노인덴테이션 실험을 수행하였다. 실험 결과를 가우시안 믹스쳐 모델로 상분석하였 고, 실리콘/알루미늄 비율이 증가할수록 재료가 균질거동을 하는 것을 관찰할 수 있었다. 본 연구결과는 강도저하를 규명하는데 직접 적인 근거로 활용될 수 있을 것으로 기대된다.

Cemento-ossifying fibroma is a benign fibrous lesion with an unknown cause, mostly asymptomatic, painless swelling of the affected jaw. This is a case report on a cystic lesion found on radiographic examination in a patient with an extraction of mandibular left tooth. A 29-year-old female was referred to Pusan National University Dental Hospital due to a radiopaque lesion in the left mandible. On the medical history examination, the left lower mandibular tooth had been extracted 4 years ago, and there were no specific findings in the general medical history. According to histopathologic findings, along with proliferation of spindle cells, cementum-like substances were observed along with irregularly shaped osseous calcified substances containing osteocytes in the cellular fibrous connective tissue. In this study, we report a case that showed cystic changes due to tooth extraction, which made it complicated to determine the differential diagnosis from the existing fibrous-osseous lesion.

The supernumerary tooth which is extra tooth in comparison to normal dentition is one of the developmental problems. The most common type of supernumerary tooth is mesiodens which may cause several complications like delayed eruption, crowding, spacing et al. Moral Incisor Hypomineralization (MIH) describes the clinical appearance of enamel hypomineralization of systemic origin affecting one or more permanent first molars that associated frequently with affected incisors. We report a case of a 6 – year – old boy who visited our clinic for removal of mesiodentes. The patient was diagnosed by mesiodentes and MIH by clinical examination and radiographic examination. Under local anesthesia, Mesiodentes were removed surgically. The demarcated opacities, a feature of MIH, were observed in the removed mesiodentes. After removal of mesiodentes, the maxillary central incisors erupted normally and in order to manage the teeth affected MIH, follow-up and fluoride varnish application were done every 3 months.

The objective of this study was to examine the expression pattern of Kelch-like ECH-associated protein 1 (Keap1) in the maxillary 2nd molar germs of rats. We used the maxillary 2nd molar germs in rats’ pup at postnatal day 3 (bell stage), 6 (crown formation stage) and 9 (root formation stage). The investigation on mRNA and protein levels were done using reverse transcription - polymerase chain reaction and western blot. Localization of Keap 1 in the maxillary 2nd molar germs were revealed through immunofluorescence staining. Keap1 from the maxillary 2nd molar germs were mostly manifested on postnatal day 3 and dramatically decreased on postnatal day 6 and 9 at mRNA and protein levels, while amelogenin and ameloblastin increased during the development of maxillary 2nd molar germs. During immunofluorescence analysis, the strong immunoreactivity against Keap1 was detected in the apical side of ameloblasts at the presecretory and secretory stages. However, Keap1 expression was hardly observed in the ameloblasts at the maturation stage. These results shows that Keap1 is strongly expressed in the presecretory and secretory ameloblasts of amelogenesis, and suggest that Keap1 may be a crucial molecule for the regulatory mechanisms tasked with the formation of enamel layer.

Ameloblastoma is a benign odontogenic tumour of epithelial origin and comprises 1% of maxillomandibular tumors or cysts. The incidence of pathological changes such as ameloblastoma from the follicle of impacted third molar was reported to have low incidence. However, there are many reports that asymptomatic third molars are related with various pathological conditions. A case of ameloblastoma secondary to third molar extraction and subsequent sagittal split ramus osteotomy (SSRO) had not been reported. At the right ramus area, radiolucent lesion had been noted at 6 years after the surgical extraction of the third molar followed by SSRO for the mandibular prognathism. The lesion was proved to be the basal cell type ameloblastoma. There had been no significant bony lesion before or 1 year after the SSRO. The tumour was successfully removed and there was no evident recurrence at 4 year of the follow up after the removal of the ameloblastoma. There are some reports suggesting the pathologic potential of the pericoronal tissues of impacted third molars to develop odontogenic keratocysts and ameloblastomas. The current case reports a rare possibility of ameloblastic change at the site of uneventful healing after third molar extraction and orthognathic surgery.

Halobacterium Halobium에서 항우울제의 부분몰 부피와 몇 가지 지질의 부유물은 과량의 부피 팽창 계를 사용하여 25 ℃에서 측정되었다. 일반적인 항우울제인 Fluoxetine의 효능은 오랫동안 지질 용해도와 관련이 있는 것으로 알려져 왔다. Halobacterium Halobium의 보라색 막에서 유일한 막 단백질인 소포의 변성은 280nm에서 흡수 변화에 의해 연구되었고 과도한 부피 팽창 계로 330nm에서 형광 변화를 보였다. 확산 교환에 의한 점성 중합체 용액의 1H NMR 분석은 측정을 위한 중요한 단계로, Halobacteriun Halobium에서 Fluoxetine의 부분 몰 부피와 입자 크기는 양성으로 측정되었다. 항우울제는 낮은 사기와 우울증에 근거하여 다양한 인지 및 정신 증상을 유발하는 질병을 예방하여 일일 수행 능력을 저하시키는 걸로 나타났다.

Sb-doped SnO2 (ATO) transparent conducting films are fabricated using horizontal ultrasonic spray pyrolysis deposition (HUSPD) to form uniform and compact film structures with homogeneously supplied precursor solution. To optimize the molar concentration and transparent conducting performance of the ATO films using HUSPD, we use precursor solutions of 0.15, 0.20, 0.25, and 0.30 M. As the molar concentration increases, the resultant ATO films exhibit more compact surface structures because of the larger crystallite sizes and higher ATO crystallinity because of the greater thickness from the accelerated growth of ATO. Thus, the ATO films prepared at 0.25 M have the best transparent conducting performance (12.60±0.21 Ω/□ sheet resistance and 80.83% optical transmittance) and the highest figure-of-merit value (9.44±0.17 × 10-3 Ω-1). The improvement in transparent conducting performance is attributed to the enhanced carrier concentration by the improved ATO crystallinity and Hall mobility with the compact surface structure and preferred (211) orientation, ascribed to the accelerated growth of ATO at the optimized molar concentration. Therefore, ATO films fabricated using HUSPD are transparent conducting film candidates for optoelectronic devices.

There are many case reports about cysts within the bones of the jaws associated with impacted third molars. When osmotic pressure is introduced into a cyst, the cyst expands and displaces the third molar. If continuity of cyst wall is lost, cystic expansion cannot occur, and the cyst cannot displace the third molar. This study analyzed four cases of pathologic migration of the third molar in ruptured cystic lesions that had formed bone tunnels and intraoral fistulas to identify the causes and factors contributing to this migration. Authors hypothesized that closure of fistulas repeated generation of pressure, it may temporarily increase the osmotic pressure within a cyst that has lost its continuity, causing displacement of the third molar. A cyst that has lost its continuity due to fistula formation within the oral cavity can cause ectopic displacement of the adjacent impacted teeth.

The presence of the microorganisms of untreated canals is one of the main reasons of the failure in the endodontic treatment. The knowledge of variations in the canal systems of the tooth is important for the successful endodontic treatment. In the maxillary molars, the presence of the two separate palatal roots is very rare variations. Although there have been several case reports of maxillary first and second molars, the case reports of maxillary third molars are very few. This case report presents the endodontic treatment of a maxillary third molar with two separate palatal roots. It is important to notice the clinical signs and analyze the radiographs carefully. The use of a microscope is helpful for the visualization of pulpal chamber, and pulpal chamber floor should be investigated thoroughly with endodontic explorer. The straight-line access for all the canal orifices is important for the success in the endodontic trea

The purpose of this case report was describe the management of impacted and dilacerated mandibular secondary primary molar with cystic formation associated with odontoma. A four-year-old male patient was presented unerupted mandibular left secondary primary molar. Radiographic examination revealed radiopaque mass on left posterior mandible, an impacted and dilacerated mandibular secondary primary molar, and a well defined osteolytic lesion surrounding crown of the impacted tooth. Under local anesthesia, the patient was treated by surgical removal of the odontoma and marsupialization of the cystic cavity. After 14 months, the secondary primary molar had erupted and there was no recurrence.

Previous studies suggested that myelinated axons innervating rat molar pulps undergo morphological changes in their peripheral course. However, little information is available on the morphological feature of the parent axons at the site of origin. We therefore investigated the size of the myelinated parent axons and their morphological features at the proximal sensory root of the trigeminal ganglion by horseradish peroxidase (HRP) injection into rat upper molar pulps and subsequent light and electron microscopy. A total of 248 HRP-labeled myelinated axons investigated were highly variable in the size. Fiber area, fiber diameter, axon area (axoplasm area), axon diameter (axoplasm diameter), and myelin thickness were 11.32 ± 8.36 μm2 (0.80~53.17 μm2), 3.99 ± 1.53 μm (1.08~9.26 μm), 8.70 ± 6.30 μm2 (0.70~41.83 μm2), 3.13 ± 1.13 μm (0.94~7.20 μm) and 0.43 ± 0.23 μm (0.07~1.06 μm), respectively. The g-ratio (axon diameter / fiber diameter) of the labeled axons was 0.79 ± 0.05 (0.61~0.91). Axon diameter was highly correlated with myelin thickness (correlation coefficients, r=0.83) but little correlated with g-ratio (r=−0.33) of individual myelinated parent axons. These results indicate that myelin thickness of the myelinated parent axons innervating rat molar pulps increase with increasing axon diameter, thus maintaining a constant g-ratio.

Squamous odontogenic tumor (SOT) is a rare benign neoplasm first described by Pullon et al. in 1975. Clinically and histologically, it is confused with ameloblastoma, carcinoma and local periodontoal disease. We report a case of SOT occuring in a 16-year-old female in the right mandibular angle location associated with an impacted molar

Matrix metalloproteinases (MMPs) have been implicated in tissue development and re-modeling. Dynamic morphological changes of tooth germs reflect involvement of these enzymes during odontogenesis. The present study was performed to investigate expression and localization of MMP-2 and MMP-9, which have been known to have type IV collagenase activities, in rat tooth germs at different developmental stages. MMP-2 expression was increased gradually in the tooth germs from cap to crown staged germs at both transcription and translation levels. The localization of this molecule was detected in secretory ameloblasts and preameloblasts. The strong immunoreactivities were occasionally seen along the basement membrane between ameloblasts (or preameloblasts) and odontoblasts (preodontoblasts). However, weak reactivity was detected in odontoblasts and reduced enamel epithelium. The level of MMP-9 expression in the tooth germs was higher in cap stage than in crown staged germs at both transcription and translation levels. They were strongly expressed in both ameloblasts and odontoblasts. Even though reduced enamel epithelium after enamel formation and inner enamel epithelium at the cap stage exhibited weak reactivity, strong reactivity was detected in dental follicles and perifollicular tissues surrounding cap staged germs. These results suggested that MMP-2 may involve degradation of the basement membrane during hard tissue formation, whereas MMP-9 might be involved in remodeling of follicular tissues.

The effect of ferrous/ferric molar ratio on the formation of nano-sized magnetite particles was investigated by a co-precipitation method. Ferrous sulfate and ferric sulfate were used as iron sources and sodium hydroxide was used as a precipitant. In this experiment, the variables were the ferrous/ferric molar ratio (1.0, 1.25, 2.5 and 5.0) and the equivalent ratio (0.10, 0.25, 0.50, 0.75, 1.0, 2.0 and 3.0), while the reaction temperature (25˚C) and reaction time (30 min.) were fixed. Argon gas was flowed during the reactions to prevent the Fe2+ from oxidizing in the air. Single-phase magnetite was synthesized when the equivalent ratio was above 2.0 with the ferrous/ferric molar ratios. However, goethite and magnetite were synthesized when the equivalent ratio was 1.0. The crystallinity of magnetite increased as the equivalent ratio increased up to 3.0. The crystallite size (5.6 to 11.6 nm), median particle size (15.4 to 19.5 nm), and saturation magnetization (43 to 71 emu.g-1) changed depending on the ferrous/ferric molar ratio. The highest saturation magnetization (71 emu.g-1) was obtained when the equivalent ratio was 3.0 and the ferrous/ferric molar ratio was 2.5.

Mesoporous silica was prepared from hydrothermal synthesis using gel mixture of tetraethylorthosilcate (TEOS) as silica source and cetyltrimethylammonium bromide (CTMABr) as a surfactant. In the optimum synthesis cause, molar ratio of template and silica changed. The surface and structure properties of mesoporous silica were determined by XRD, SEM, TEM and BET. Also, surface potential of mesoporous silica was measured using zeta potential. N2 adsorption isotherm characteristics, including the specific surface area (SBET), total pore volume (VT), and average pore diameter (DBJH), were determined by BET. As a result, SBET of 100 m² /g～1500 m² /g was determined from the N2 adsorption isotherm. Also, the average pore diameter was 2 nm∼4 nm. Mesoporous silica's surface potential of minus charge was determined from zeta potential.