The change of phenolic compounds and radical scavenging activity of black soybean flours after germination and roasting treatment were evaluated as a part of the purpose of setting the quality of black soybean flours for each application. The moisture content of roasted black soybean flours decreased significantly according to roasting temperature and time, and the crude ash, protein, and fat contents increased. Water binding capacity of roasted black soybean flours without and with germination increased significantly according to roasting temperature and time, however water solubility index and swelling power decreased. The lightness of roasted black soybean flours was significantly decreased, and the redness and yellowness increased. The phenolic compounds and radical scavenging activity of roasted black soybean flours increase with increasing roasting temperature and time. The total polyphenol contents of roasted black soybean flours without and with germination were 5.43∼7.81 and 4.52∼6.17 mg GAE/g, and total flavonoid contents were 2.90∼3.50 and 2.34∼3.01 mg CE/g, respectively. DPPH radical scavenging activity of roasted black soybean flours without and with germination was 254.98∼415.05 and 171.95∼295.15 mg TE/100 g, and ABTS radical scavenging activity was 459.74∼596.37 and 422.95∼526.85 mg TE/100 g, respectively. As a result, it is necessary to set quality standards for each application considering the quality and antioxidant properties of roasted black soybean flours.

Radiotherapy (RT) is a mainstay in the treatment of head and neck squamous cell carcinoma (HNSCC). For locally advanced HCSCC, concurrent chemoradiotherapy (CCRT) benefits HCSCC patients in terms of better survival and loco-regional control. In this study, we evaluated changes in oral microbiota in patients, who received CCRT for head and neck cancer. Oral rinsed samples were weekly collected before and during CCRT and at 4 weeks following treatment from HNSCC patients, who had received 70 Gy of radiation delivered to the primary sites for over 7 weeks and concurrent chemotherapy. Oral microbiota changes in three patients were analyzed by next-generation sequencing using 16S rRNA 454 pyrosequencing. On an average, 15,000 partial 16S rRNA gene sequences were obtained from each sample. All sequences fell into 11 different bacterial phyla. During early CCRT, the microbial diversity gradually decreased. In a patient, who did not receive any antibiotics during the CCRT, Firmicutes and Proteobacteria were the most abundant phylum. During the early CCRT, proteobacteria gradually decreased while Firmicutes increased. During the late CCRT, firmicutes gradually decreased while Bacteroides and Fusobacteria increased. In all the patients, yellow complex showed a gradual decrease, while orange and red complex showed a gradual increase during the CCRT. At 4 weeks after CCRT, the recovery of oral microbiota diversity was limited. During CCRT, there was a gradual increase in major periodontopathogens in association with the deterioration of the oral hygiene. Henceforth, it is proposed that understanding oral microbiota shift should provide better information for the development of effective oral care programs for patients receiving CCRT for HNSCC.

양파의 이용 다변화를 위하여 껍질과 육질을 각각 100∼300℃의 조건에서 아임계수로 추출하여 그 특성을 조사하였다. 양파 껍질과 육질 모두 추출 온도가 상승함에 따라 아임계수 추출물의 페놀 함량이 증가하였다. 양파 껍질 추출물은 250℃에서 quercetin, quercetin 3,4'-diglycoside, quercetin-3- glucoside의 함량이 가장 높았고, 육질 추출물은 quercetin 3,4'-diglycoside 의 함량이 200℃에서 가 장 높았으나 quercetin 및 quercetin-3-glucoside의 함량은 상대적으로 미미하였다. 양파 껍질과 육질 추출물의 quercetin및 그 배당체 함량은 300℃에서 급격히 감소하였다. 양파 껍질과 육질 모두 추출 온도가 증가할수록 아임계수 추출물들의 DPPH 라디칼 소거능과 alcohol dehydrogenase 활성을 향상시 켰다. 이상의 결과는 적절한 아임계수 조건이 양파 추출물의 생리활성을 향상시킬 수 있음을 시사한다.

Recently, applications of high voltage impulse (hereafter HVI) technique to desalting, sludge solubilization and disinfection have gained great attention. However, information on how the operating condition of HVI changes the water qualities, particularly production of hydroxyl radical (·OH) is not sufficient yet. The aim of this study is to investigate the effect of operating conditions of the HVI on the generation of hydroxyl radical. Indirect quantification of hydroxyl radical using RNO which react with hydroxyl radical was used. The higher HVI voltage applied up to 15 kV, the more RNO decreased. However, 5 kV was not enough to produce hydroxyl radical, indicating there might be an critical voltage triggering hydroxyl radical generation. The concentration of RNO under the condition of high conductivity decreased more than those of the low conductivities. Moreover, the higher the air supplies to the HVI reactor, the greater RNO decreased. The conditions with high conductivity and/or air supply might encourage the corona discharge on the electrode surfaces, which can produce the hydroxyl radical more easily. The pH and conductivity of the sample water changed little during the course of HVI induction.

Based on the bamboo texts of the early Western Han dynasty excavated at Zhangjiashan, this thesis investigates the evolution of Han characters by tracing the origin of form mélange of radicals and components in Han characters. In this thesis, “mélange” refers to the phenomenon of miswriting characters and radicals of different forms, pronunciations and meanings, or components of irrelevant forms and meanings as those of the same form, without limiting to the mélange of characters of similar forms. First, the author set the prototypes of different sets of mixed radicals or components in the Zhangjiashan Han Bamboo Texts in order to restore their original appearances. Then, the author traced if the writing of particular mixed radicals or components are found in the survived bronzeware script of the Western Zhou dynasty and the Spring and Autumn Period, the characters of the six countries in the Warring Period or the characters of the Qin dynasty. The author also examined the influence on form mélange of the “clerical script transformation” where “contours” were transformed into “strokes” in Han characters, to elucidate the radical or component mélange of the Zhangjiashan Han Bamboo Texts.

본 연구에서는 TiO2 nanotube 광촉매의 고도산화처리능을 비교하기 위해서 OH 라디칼 생성 력을 평가하고자 하였다. 자외선 조사에 따른 Probe compound인 4-Chlorobenzoic acid (pCBA)의 농 도 감소에 따라 OH radical 생성량을 산정하는 방법으로 광촉매 효율을 평가하였는데, TiO2 nanotube 표면에서의 전자의 흐름을 원활하게 하기 위하여 전기적 에너지를 주었을 시 광촉매 효율의 증가 가능 성 또한 확인하고자 자외선 조사 시 전류밀도를 인가하는 방법으로 실험을 진행하였다. 실험에 사용된 TiO2 nanotube는 전극효과를 부여하기 위해 양극산화법으로 티타늄판을 이용하여 제조하였으며, pCBA 용액에는 전도도를 부여하기 위하여 NaCl을 첨가하여 전해질로 사용하였다. 정전류 정전압 조건하에서 자외선조사 실험을 진행하였으며, 전류가 흐르는 광촉매에 자외선 조사 시 OH 라디칼 생성량은 광촉매 없이 자외선만 조사하였을 때에 비해 약 5.6배, TiO2 광촉매와 함께 자외선을 조사하였을 보다 약 2.2 배 증가하였다. 결과적으로 광촉매반응에 전기적 에너지를 부여하였을 시 시너지효과를 가져올 수 있는 가능성을 확인할 수 있었다.

The intermediate product resulting from the radical degradation experiment of PCE and the atomic charge gained through Gaussian03W were compared against each other. The result was that the ratio of PCE radical degradation was almost 98% or higher after the 9 hr point in reaction time. The reaction speed constant was 0.16 hr-1 and it followed the first reaction. We could see that at each location of the PCE molecule, dechlorination happened at a point where the negative atomic charge was the greatest. Moreover, the intermediate product of PCE radical degradation that was confirmed in the experiment and literature coincided exactly with the intermediate product in the atomic charge calculation. Therefore, when the atomic charge is calculated, the radical degradation pathway of the organic chlorine compound could be forecast.

Introduction Since most companies are constantly confronted with incremental technology obsolescence and the risk of disruptive innovations, they have been struggling to pursue both incremental and radical new product developments (NPD). Due to these practical concerns, scholars have conducted research to reveal which factors promote “ambidexterity (O’Reilly & Tushman, 2008)” of both explorative activities, including radical NPD, and exploitative activities, including incremental NPD, mainly focusing on organizational structures and systems. For example, previous studies have suggested organizational structures (Gibson & Birkinshaw, 2004), cross-functional integration (Brettel, Heinemann, Engelen and Neubauer, 2011), and management systems (Benner & Tushman, 2003) are the factors to promote ambidexterity. Furthermore, recent studies have emerged suggesting the importance of cognition in pursuing both radical and incremental NPD (Smith & Tushman, 2005; Eling, Griffin, & Langerak, 2014). Although the importance of cognitive processes in NPD has been suggested in some studies, the research exploring these roles is scarce. Therefore, this study attempts to fill in the gaps by revealing the roles of cognitive processes (analytical processing, intuitive processing, and associative processing) on radical and incremental NPD performance empirically. Theoretical Background and Literature Review The purpose of this section is to attempt to reveal the points not addressed adequately in extant literature. In order to do so, firstly, this section tries to classify the cognitive processing in previous studies, according to some criteria. Secondly, the section reviews the empirical research regarding the effects of cognitive processing on decision-making. Lastly, it goes on to compare the reviewed empirical studies with the classification of cognitive processing that are indicated and attempts to review the gaps in previous research. The research on cognitive processing Referring to the rule-based processing and the associative processing, proposed in Smith & Decoster (2000), as well as the logico-deductive manner of rational choice and the associative thinking, proposed in Gavetti (2005, 2012), this study proposes three types of cognitive processing: analytical, intuitive, and associative processing.Analytical processing involves a comprehensive consideration of various factors, such as market environments, competitors’ behaviors and strategic alternatives, to make a judgement. One example of analytical processing is that we use a 3C framework to make a judgement regarding a new product concept. Intuitive processing involves making a judgement based on intuition, or judging without deliberation. One example of intuitive processing is adopting the product design that arouses feeling of rightness of choice (Dijksterhuis & Nordgren, 2006) or excitement (Agor, 1986) without clear bases. Associative processing involves consciously searching for a past experience or knowledge which is similar to a current situation, and making a judgement based on it. One example of this is when we intentionally recall a past experience in NPD, or a case in another industry that is similar to the current NPD situation, and determine the strategy by following it. The empirical research on the effect of cognitive processing There is an accumulation of empirical research on the effect of cognitive processing on decision making performance, management, and marketing literature. Dean and Sharfman (1996) empirically considered the relationship between the procedural rationality, defined as “the extent to which the decision process involves the collection of information relevant to the decision and the reliance upon analysis of this information in making the choice” (p. 373) and strategic decision effectiveness. Menon, Bharadwaj, Adidam and Edison (1999) empirically examines the relationship between situation analysis, referring to “rational and systematic consideration of the organizational SWOTs in a marketing strategy domains” (p. 21), and market performance, strategy creativity, and organizational learning. Yamashita, Fukudome, Uehara, and Sasaki (2012) studies the relationship between marketing strategy, referring to the extent that the marketer uses STP framework in the phase of decision making, and business unit’s performance. The constructs, such as procedural rationality, situational analysis, and marketing strategy, seem to approximately correspond to the analytical processing indicated in the previous section. Although previous research reviewed so far only focuses on analytical processing, there is research considering other cognitive processing. De Visser et al. (2014) examines the effects of NPD team’s intuitive information processing and analytical information processing on incremental and radical NPD’s overall performance. This study suggests that analytical processing affects overall NPD performance positively while intuitive processing affects only radical NPD performance in a positive manner. Table 1 indicates the arrangement of the reviewed empirical studies. The gaps in the literature From the previous research review, this study indicates three points not addressed adequately in the literature. First, as shown in Table 1, there is little research focusing on cognitive processing aside from analytical processing (especially on associative processing). Second, the research considering the relationship between cognitive processing and radical/ incremental NPD performance is scarce (except for de Visser etal (2014)). Third, little research has considered the effects of the cognitive processing of a new product development (NPD) leader, on the NPD performance. Given these points, this study focuses on the cognitive process of a NPD leader and considers the effects of analytical processing, intuitive processing, and associative processing, on incremental/ radical NPD project performance. Table 1 Research Hypotheses Generally, the uncertainty of incremental NPD projects is low. In such situations, it is relatively easy for NPD leaders to collect and analyze various data for judgements (analytical processing), enabling them to estimate and predict the surrounding situation more accurately. Thus, analytical processing affects the incremental NPD project positively. Using intuitive processing, a NPD leader makes judgements, automatically referring to past repeated experiences (cf. Smith & DeCoster, 2000). These judgements are correct in most cases, but judgement errors are sometimes brought about, due to inaccurate application of repeated experiences to a judgement. Furthermore, due to its automatic and preconscious nature, the bases of the judgement guided by intuitive processing cannot be explained clearly (Smith & DeCoster, 2000; Eling et al., 2014), which seems to increase the frequency of conflicts. Taking these effects in consideration, this study predicts that intuitive processing does not affect incremental NPD project performance. Using associative processing, a NPD leader replaces an uncertain situation with a past experience or knowledge that is more familiar to them, in order to make a judgement. However, such replacement is not effective in incremental NPD projects because, in general, they tend to be less uncertain. Thus, it is predicted that associative processing does not affect incremental NPD project performance. H1a: As a NPD leader uses the analytical processing more frequently in an incremental NPD project, the NPD project performance will be higher. H1b: The frequency of using intuitive processing by a NPD leader does not affect the incremental NPD project performance. H1c: The frequency of using associative processing by a NPD leader does not affect the incremental NPD project performance. Generally, as the needs of radical NPD deviates from organizations’ existing routines (Smith & Tushman, 2005), its uncertainty increases. In these situations, analytical processing is not appropriate for judgements due to the factors such as a lack of information and defined criteria (March, 2006). Part of the previous research suggests the positive effect of intuitive processing on radical NPD performance due to its tendency to generate creative ideas (de Visser et al., 2014). Given this, it is predicted that intuitive processing by a NPD leader positively affects the radical NPD performance. In contrast, it is also said that intuitive processing is likely tocause error of judgement in novel situations or strategies (cf. Miller & Ireland, 2005), and conflicts. Considering these, this study does not posit that any directional relationship between intuitive processing and radical NPD project performance. Associative processing can cope with uncertain situations by relating and drawing similarities from a previous familiar experience to the current uncertain situation (Gavetti, 2012). In addition, since associative processing is a conscious mental activity, its risk of error of judgement is lower than that of intuitive processing (cf. Stanovich & West, 2000). Considering this, it is predicted that there will be a positive effect of associative processing on radical NPD project performance. H2a: The frequency of using analytical processing by a NPD leader does not affect the radical NPD project performance. H2b: The frequency of using intuitive processing by a NPD leader affects the radical NPD project performance. H2c: As a NPD leader uses the associative processing more frequently in a radical NPD project; the NPD project performance will be higher. The depth of NPD leader’s experience refers to the extent that he has engaged in many NPD projects in one product category. The width of the NPD leader’s experience means the extent that he has engaged in NPD projects in various product categories. For want of space, the detailed explanation of H3 is skipped in this abstract. H3: The depth and width of the NPD leader’s experience moderate the relationship between cognitive processing and NPD project performance. Figure 1 METHODOLOGY This study uses the data collected from Japanese high-tech manufacturing companies, through survey research. The collected data will be used to empirically test the hypotheses. At the empirical test, the samples will be divided into two groups according to the NPD radicalness, and each group will be applied hierarchical multiple regression analysis to examine the relationship among the constructs. This study incorporates three independent variables, one dependent variable, three moderator variables and three control variables, into the model. The independent variables are analytical, intuitive, and associative processing. The dependent variable is overall NPD project performance. The moderator variables are NPD radicalness, depth and width of NPD leader’s experience. The control variables are firm size, devoted resource and the development period of a new product. The main variables of this model will be measured as follows. The scales of analytical processing and intuitive processing are developed, referring to those of Epstein et al. (1996) and de Visser et al. (2014). The scale of associative processing is developed for this study by drawing on the extant literature such as Gavetti(2005; 2012). Overall NPD project performance is measured by adopting the scale of Hoegl, Weinkauf, and Gemuenden (2004). The results of the analysis will be reported at the presentation in 2016 Global Marketing Conference in Hong Kong.

The aim of this work was to select suitable fermentation treatments for the efficient bioconversion of cactus (Opuntia humifusa Raf.) bioactive components with an improved radical scavenging activity for use as a nutraceutical. To obtain microorganisms for the microbial conversion of cactus, Leuconostoc mesenteroides ATCC8294, Lactobacillus plantarum KCTC 3099, Lactobacillus plantarum KERI 236 and Monascus pilosus KCCM 60029 (ATCC 22080) were used for fermentation. Fermentation by Lac. plantarum KCTC 3099 was the most effective at scavenging 1,1-diphenyl-2-picrylhydrazyl hydrate (DPPH) and 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicals and reducing iron ( ). In particular, uronic acid levels showed a remarkable increase in fermentation. The polyphenol and quercetin content of the fermented cactus showed large increases from 108.65 μg/mL and 2.71 μg/mL to 227.83 μg/mL and 9.73 μg/mL, respectively, showing a maximum level at 36 h of fermentation with Lac. plantarum KCTC 3099. Thus, cactus fermentation with Lac. plantarum is an useful process for the enhancement of antioxidant contents and activity of fresh cactus.

This study investigated the changes in chemical components, antioxidant compounds, and activity before (BG) and after germinated (AG) brown rice in order to promote the availability of these beneficial factors. The GABA content of BG and AG brown rice were 0.07~6.61 and 11.13~49.72 mg/100 g, respectively. The α-amylase activity of AG brown rice was 1.77~70.25 unit/g fold higher than it was in BG brown rice. Total polyphenol and flavonoid contents, which are known to be related to antioxidation, were higher in BG brown rice than in AG brown rice. The total polyphenol contents of BG and AG brown rice were 10.52~36.38 and 11.38~26.33 mg/100 g, and the total flavonoid contents were 3.55~13.39 and 3.52~9.78 mg/100 g, respectively. Also, DPPH radical scavenging activity was 57.64~251.34 and 50.49~213.35 mg TE/100 g, respectively. ABTS radical scavenging activity and total tannin content showed a similar trend to DPPH radical scavenging activity. We expect that this data will be useful in the manufacturing of food products.

Compound ideographs (會意, Hui Yi) are formed by two or more phonetic or semantic parts. But when both parts are radicals, how should we classify the character? This issue involves not just identification of the syntax, but also the context. In other words, the issues lies in how the radical of a compound ideograph signifies the meaning of the character through the logic of the radical and what role the radical plays in the overall definition of the character. This has been a puzzling issue to many and calls for in-depth exploration. Classification of Chinese character radicals can be divided into two major systems; philology principles and dictionary reference principles. The former is mainly based on the meaning and supplemented by the form. This radical system emerged from the Shuowen Jiezi (說文解字), emphasizing the relationship between the radical and the subordinate part in terms of the structure and semantics. The latter is mainly based on the form and supplemented by meaning. This system emerged from Wujing Wenzi. The “Li Bu (立部)” and “Gui Bu (歸部)” classification system used in the Kangxi Dictionary, on the other hand, follows the principle, “Easy to reference with logical grouping of semantics without contradicting the intended meaning given by the creator.” This principle was an attempt to integrate the systems of philology principle-based and dictionary reference principle-based radical systems. Based on the above, this research studies the “Gui Bu” classification of compound ideographs, focusing on the “frequently-used characters” published by the Ministry of Education, with an attempt to clarify the issues relating to the “Gui Bu” classification of the commonly-used compound ideographs in the Shuowen Jiezi and Kangxi Dictionary.

본 연구에서는 국산밀 품종에 대해 발아시간에 따른 항산 화 성분 및 항산화 활성을 측정하였다. 발아시간에 따른 국산 밀 에탄올 추출물의 총 폴리페놀, 플라보노이드 및 탄닌 등 페놀성분의 함량은 발아시간에 따라 유의적인 차이를 보이 는 것으로 나타났다. 무처리 금강밀, 조경밀, 백중밀 및 고소 밀의 총 폴리페놀 함량은 13.74, 15.05, 16.84 및 13.02 mg GAE/100 g이었으며, 발아시간이 증가함에 따라 유의적으로 증가하는 경향을 보였다(p<0.05). 총 플라보노이드 함량은 각 각 5.11, 6.72, 6.28 및 5.43 mg CE/100 g이었으며, 발아시간이 증가함에 따라 큰 차이를 보이지 않았으나, 유의성을 보이는 것으로 나타났다(p<0.05). 총 탄닌 함량은 각각 9.19, 8.86, 8.93 및 8.66 mg TAE/100 g이었으며, 발아시간이 증가함에 따 라 큰 차이를 보이지 않았으나, 유의성을 보이는 것으로 나타 났다(p<0.05). 금강밀, 조경밀, 백중밀 및 고소밀의 DPPH 라 디칼 소거활성은 각각 30.77, 23.88, 25.35 및 18.73 mg TE/100 g이었으며, 25℃에서 72시간 발아 시료가 각각 47.47, 44.17, 38.22 및 42.85 mg TE/100 g으로 유의적으로 높은 활성을 보 이는 것으로 나타났다(p<0.05). ABTS 라디칼 소거활성은 각 각 83.42, 88.53, 88.87 및 79.97 mg TE/100 g이었으며, 발아시 간이 증가함에 따라 유의적으로 증가하는 경향을 보였다 (p<0.05). 이상의 결과 국산밀의 발아를 통하여 페놀성분 및 라디칼 소거활성이 증진된 효과를 얻을 수 있는 것을 확인할 수 있었다.

The purpose of this study includes: Firstly, to examine the effects of corporate entrepreneurship on market orientation, radical innovation, and organizational performance. Secondly, to examine the mediating effect of the market orientation, radical innovation on the relationship between corporate entrepreneurship and organizational performance. In order to verify the relationships and mediating effect, data were collected from convenient sample of 269 employees at small and medium enterprises in Busan, Ulsan, Gyeongju city to test theoretical model and its hypotheses. All data collected from the survey were analyzed using with SPSS 18.0 and AMOS 18.0. This study reports findings as followed: first, the relationship between the corporate entrepreneurship and the market orientation is positively related. Second, there was also a positive correlation between the corporate entrepreneurship and the radical innovation. Third, there was also a positive correlation between the market orientation and the radical innovation. Fourth, the relationship between the market orientation and the organizational performance is positively related. Fifth, there was also a positive correlation between the corporate entrepreneurship and the organizational performance. Sixth, there was also a positive correlation between the radical innovation and the organizational performance. Finally, the market orientation played as a partial mediator on the relationship between corporate entrepreneurship and radical innovation. The market orientation and radical innovation played as a partial mediator on the relationship between corporate entrepreneurship and organizational performance. Also, the radical innovation played as a partial mediator on the relationship between market orientation and organizational performance. Based on these findings, the limitations of the study and some directions for future studies were presented.

Calocybe indica (Purkayastha, 1974), Milky mushroom, is a relatively new to the world of mushroom industry, which is belong to Lyophyllaceae of Basidiomycota, and commonly used as edible mushroom in India and Southern Asia country. This study was conducted to investigate the free radical scavenging, skin whitening and anti-collagenase activities of methanol extract from fruiting body of C.indica cultivated in Bangladesh. In addition, the polyphenol compounds of the extract were analyzed by HPLC. The mushroom extract showed good activity in lipid peroxidation which ranged from 29.35% to 55.39% at the concentration 0.125~2.0 mg/mL. The scavenging activity of the extract on 1,1-diphenyl-2-picrylhydrazy radicals were from 20.22~83.93% at the same tested concentration, which were comparable with the positive control BHT. The hydroxyl radical scavenging activity of the extract was 76.24~93.92%. The skin whitening effect of the mushroom extract was performed with UV light protecting, tyrosinase and DOPA inhibitory activities. The methanol extract absorbed UV-B wavelength with maximum level of 0.356 at 280 nm. The tyrosinase and DOPA inhibitory activities of the extract were ranged from 30.36 ~ 66.25% and 7.13 ~ 30.25% at the concentration 0.125~2.0 mg/mL, respectively. Furthermore, anti-collagenase activity were determined by measuring collagenase and elastase inhibitory activity. The collagenase and elastase inhibitory activity of the extract were 42.77% and 51.08% at the concentration 1.0 mg/mL, respectively. The experiment results suggested that fruiting body of Calocybe indica could be used as natural skin care and antioxidant agents.

본 연구에서는 포도즙의 양(0 g, 50 g, 100 g, 150 g, 200 g)을 다르게 첨가하여 포도 양갱을 제조하고, pH, 당도, 색도, 기계적 물성, 총 페놀 함량, DPPH, 관능평가를 실시하였다. 포도양갱의 pH는 포도즙의 첨가량이 증가할수록 pH 값이 낮아지면서 유의적인 차이를 보였으며, 당도는 대조군이 1.47 Brix로 가장 낮게 나타났고, 포도즙 첨가량이 증가할수록 당도가 점점 높아져 유의적인 차이를 보였다. 색도는 명도값(L값)과 황색도(b값)이 포도즙 첨가량이 증가할수록 감소하였으나, 적색도(a값)는 그와 반대로 증가하였다. 물성 측정 결과, 포도즙 첨가가 증가할수록 경도는 증가하는 경향을 보였지만, 탄력성, 응집성, 점착성, 씹힘성은 모두 감소하는 경향을 보였다. 총 페놀 함량은 포도즙 첨가량이 증가할수록 높은 값을 보였으며, DPPH radical 소거능도 총 페놀 측정 결과와 마찬가지로 대조군에서 가장 낮은 활성을 나타내었으며, 포도즙 첨가가 증가할수록 높은 항산화 활성을 보였다. 관능평가 결과, 색, 향, 맛 등의 전체적인 기호도에서 포도즙 150 g 첨가군이 가장 높은 점수를 받았다. 이상의 결과를 종합하여 볼 때 항산화 실험에서 포도즙 200 g 첨가군의 결과가 가장 좋았으나, 관능검사 결과, 포도즙 150 g 첨가군을 가장 선호하는 결과를 함께 고려해 볼 때는 포도즙 150 g이 첨가된 양갱시료의 실용화가 바람직 할 것으로 사료된다.

Russula compacta, a wild mushroom, belongs to Russulaceae, Russulales of Basidiomycota. This study was conducted to evaluate the free radical scavenging, anti-inflammatory, anticholinesterase and anti-α-glucosidase effects from fruiting bodies of R. compacta extracted with methanol and hot water. In 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging effects, the methanol and hot water extracts showed good scavenging effects comparable with positive control, BHT. The chelating effect of methanol and hot water extracts of the mushroom were significantly higher than the positive control, BHT. The reducing power of the methanol and hot water extracts of the mushroom were lower than the positive control at the concentrations tested. In the HPLC anaysis of phenolic acids profile of the mushroom extract, 7 phenolic acids such as gallic acid, vanillin, rutin hydrate, resveratol, quercetin formononetin, and biochanin-A were detected. Nitric oxide (NO) production in lipopolysaccahride (LPS) activated RAW 264.7 cells was inhibited by 1.5-fold with the treatment of methanol extract when compared with the control. In the anti-cholinesterase activity assay, the methanol extract inhibited the acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) effects by 73.9% and 81.05% at the 1.0 mg/mL concentration, whereas galanthamine, the standard drug, inhibited the AChE and BChE activities by 97.80% and 81.12%, respectively at the same concentration. The methanol and hot water extracts of the mushroom inhibited the α-glucosidase activity by 55.44% and 62.00%, respectively at the 2.0 mg/mL concentration, while acarbose, the positive control inhibited the α-glucosidase activity by 81.81% at the 2.0 mg/mL concentration. From the experimental results, the fruiting bodies of R. compacta contained natural antioxidant, anti-inflammatory, anti-cholinesterase, and anti-diabetic substances, which might be used for health foods.