Single-walled carbon nanotubes (SWNT) have a strong and stable near-infrared (nIR) fluorescence that can be used to selectively detect target analytes, even at the single molecule level, through changes in either their fluorescence intensity or emission peak wavelength. SWNTs have been employed as NIR optical sensors for detecting a variety of analytes. However, high costs, long fabrication times, and poor distributions limit the current methods for immobilizing SWNT sensors on solid substrates. Recently, our group reported a protocol for SWNT immobilization with high fluorescence yield, longevity, fluorescence distribution, and sensor response, unfortunately this process takes 5 days to complete. Herein we report an improved method to immobilize SWNT sensors that only takes 2 days and results in higher fluorescence intensity while maintaining a high level of SWNT distribution. We performed surface morphology and chemical composition tests on the original and new synthesis methods and compared the sensor response rates. The development of this new method of attaching SWNT sensors to a platform allows for creation of a sensing system in just 2 days without sacrificing the advantageous characteristics of the original, 5-day platforms.

Background: In healthy dentin conditions, odontoblasts have an important role such as protection from invasion of pathogens. In mammalian teeth, progenitors such as mesenchymal stem cells (MSCs) can migrate and differentiate into odontoblast-like cells, leading to the formation of reparative dentin. For differentiation using stem cells, it is crucial to provide conditions similar to the complex and intricate in vivo environment. The purpose of this study was to evaluate the potential of differentiation into odonto/ osteoblasts, and compare co-culture with/without epithelial cells. Methods: MSCs and epithelial cells were successfully isolated from dental tissues. We investigated the influences of epithelial cells on the differentiation process of dental pulp stem cells into odonto/osteoblasts using co-culture systems. The differentiation potential with/without epithelial cells was analyzed for the expression of specific markers and calcium contents. Results: Differentiated odonto/osteoblast derived from dental pulp tissue-derived mesenchymal stem cells with/without epithelial cells were evaluated by qRT-PCR, immunostaining, calcium content, and ALP staining. The expression of odonto/ osteoblast-specific markers, calcium content, and ALP staining intensity were significantly increased in differentiated cells. Moreover, the odonto/osteogenic differentiation capacity with epithelial cells co-culture was significantly higher than without epithelial cells co-culture. Conclusions: These results suggest that odonto/osteogenic differentiation co-cultured with epithelial cells has a more efficient application.

이 연구에서는 CFRP 케이블의 압착형 정착장치의 강종에 따른 피로성능을 평가하였다. 실험결과, CFRP 케이블 압착형 정착시스템은 정착장치의 강종에 상관없이 도로교설계기준의 포스트텐션용 정착 구에 대한 피로시험 조건을 만족시켰다. 그러나 피로시험이후 인장성능 실험에서 SM45C 강종의 정착 장치는 최대내력 도잘전에 케이블과 정착장치 사이에서 미끄러짐이 발생하였으며, 듀플렉스 강종의 정 착장치는 최대 내력 도달과 동시에 CFRP 케이블이 파단되었다.

목적: 라이프스타일 행동에 반영된 가치체계를 측정하기 위한 Yonsei Lifestyle Profile-Values (YLP-V)의 구성타당도와 신뢰도를 검증하였다. 연구방법: 온라인 리서치 기관에 등록된 만 55세 이상의 지역사회 거주 중고령자 및 노인 300명을 대상으로 YLP-V를 사용하여 자료를 수집하였다. 수집된 자료는 기술통계, 차별기능문항, 요인분석을 실시하였다. 요인분석은 요인구조 추정을 위한 탐색적 요인분석과 4가지 경쟁모델(단일요인, 계층적 요인, 다차원 요인, 이중요인)에 대한 확인적 요인분석을 통해 비교하고 타당성을 확인하였다. 결과: 목표회전을 통한 탐색적 요인분석 결과, YLP-V의 활동(activity, 5문항), 관심(interest, 4문항), 의견 (opinion, 9문항)에서 목표행렬에서 0.4 이상의 부하량을 갖는 것을 확인하였다. 확인적 요인분석 결과, 이중요인 모델(χ2 = 164.58**, degree of freedom = 117, root mean square error of approximation = 0.05, standard root mean residual = 0.04, comparative fit index = 0.95, Turker Lewis index = 0.93)이 가장 우수하게 나타났다. 결론: 라이프스타일에서 미시적 접근이 가능한 YLP-V 개발 근거와 일관성 있는 요인구조를 확인하였다. 이는 YLP-V가 총 18문항의 활동, 관심, 의견에 대한 이중요인 구조로 타당성을 확인하였으며, 건강 라이프스타 일에서 행동에 반영된 가치체계 측정과 이해에서 활용될 수 있을 것이다.

The aim of this study is to ensure the structural integrity of a canister to be used in a dry storage system currently being developed in Korea. Based on burnup and cooling periods, the canister is designed with 24 bundles of spent nuclear fuel stored inside it. It is a cylindrical structure with a height of 4,890 mm, an internal diameter of 1,708 mm, and an inner length of 4,590 mm. The canister lid is fixed with multiple seals and welds to maintain its confinement boundary to prevent the leakage of radioactive waste. The canister is evaluated under different loads that may be generated under normal, off-normal, and accident conditions, and combinations of these loads are compared against the allowable stress thresholds to assess its structural integrity in accordance with NUREG-2215. The evaluation result shows that the stress intensities applied on the canister under normal, off-normal, and accident conditions are below the allowable stress thresholds, thus confirming its structural integrity.

A transfer cask serves as the container for transporting and handling canisters loaded with spent nuclear fuels from light water reactors. This study focuses on a cylindrical transfer cask, standing at 5,300 mm with an external diameter of 2,170 mm, featuring impact limiters on the top and bottom sides. The base of the cask body has an openable/closable lid for loading canisters with storage modules. The transfer cask houses a canister containing spent nuclear fuels from lightweight reactors, serving as the confinement boundary while the cask itself lacks the confinement structure. The objective of this study was to conduct a structural analysis evaluation of the transfer cask, currently under development in Korea, ensuring its safety. This evaluation encompasses analyses of loads under normal, off-normal, and accident conditions, adhering to NUREG-2215. Structural integrity was assessed by comparing combined results for each load against stress limits. The results confirm that the transfer cask meets stress limits across normal, off-normal, and accident conditions, establishing its structural safety.

In this research, a new Test and Evaluation (T&E) procedure for defense AI systems is proposed to fill the existing gap in established methodologies. This proposed concept incorporates a data-based performance evaluation, allowing for independent assessment of AI model efficacy. It then follows with an on-site T&E using the actual AI system. The performance evaluation approach adopts the project promotion framework from the defense acquisition system, outlining 10 steps for R&D projects and 9 steps for procurement projects. This procedure was crafted after examining AI system testing standards and guidelines from both domestic and international civilian sectors. The validity of each step in the procedure was confirmed using real-world data. This study's findings aim to offer insightful guidance in defense T&E, particularly in developing robust T&E procedures for defense AI systems.

In this study, the evaluation items related to the effectiveness evaluation of the LVC (Live, Virtual, Constructive) training system of the Air Force were derived and the weights of each item were analyzed. The LVC training system evaluation items for AHP (Analytic Hierarchy Process) analysis were divided into three layers, and according to the level, 3 items were derived at level 1, 11 items at level 2, and 33 items at level 3. For weight analysis of evaluation items, an AHP-based pairwise comparison questionnaire was conducted for Air Force experts related to the LVC training system. As a result of the survey, related items such as (1) Achievement of education and training goals (53.8%), (1.2) Large-scale mission and operational performance (25.5%), and (1.2.1) Teamwork among training participants (19.4%) was highly rated. Also, it was confirmed that the weights of evaluation items were not different for each expert group, that is, the priority for importance was evaluated in the same order between the policy department and the working department. Through these analysis results, it will be possible to use them as evaluation criteria for new LVC-related projects of the Air Force and selection of introduction systems.

This study aimed to develop a solid self-nanoemulsifying drug delivery system (solid-SNEDDS) to enhance the formulation of ketoconazole (KTZ), a BCS Class II drug with poor solubility. Ketoconazole, which is insoluble above pH 3, requires solubilization for effective delivery. This SNEDDS comprises oil, surfactant, and co-surfactant, which spontaneously emulsify in the gastrointestinal tract environment to form nanoemulsions with droplet sizes less than 100 nm. The optimal SNE-vehicle composition of oleic acid, TPGS, and PEG 400 at a 10:80:10 weight ratio was determined based on the smallest droplet size achieved. This composition was used to prepare liquid SNEDDS containing ketoconazole. The droplet size and polydispersity index (PDI) of the resulting liquid SNEDDS were analyzed. Subsequently, solid-SNEDDS was fabricated using a spray-drying method with solidifying carriers such as silicon dioxide, crospovidone, and magnesium alumetasilicate. The physicochemical properties of the solid-SNEDDS were characterized by scanning electron microscopy and powder X-ray diffraction, and its solubility, droplet size, and PDI were evaluated. In particular, the solid-SNEDDS containing ketoconazole and crospovidone in a 2:1 weight ratio exhibited significantly enhanced solubility, highlighting its potential for improved medication adherence and dissolution rates.

As a means to activate eco pastoral system in alpine grassland, the government can consider public pastures, which are currently unused, to scale them up into public ranches. Depending on ownership and operation, four management models proposed as follows: 1) Government-Owned and Operated with Balanced Profit and Loss 2) Government-Owned and Operated with Revenue Generation 3) Government-Owned but Privately Operated by Outsourced to Professional Manager 4) Full Privatization (Ownership and Operation by Private Individuals). The study outlined above proposes four management models for the activation of eco pastoral system in alpine grassland. It also suggests methods for the selection and performance evaluation of manager to establish a profitable structure. Additionally, the research provides management methods for the conservation of grazing ecology in pastoral ecosystems. Particularly, the adaptation of tools commonly used in South Korean business sector for the selection and performance evaluation of manager within the system of the proposed management models. This aspect is deemed valuable as it aligns these tools with the specific characteristics of eco pastoral system in alpine grassland, contributing not only to the effective implementation of the models but also to the enhancement of the revenue structure.

PURPOSES : The number of snowfall and the amount of snowfall are gradually increasing, and due to the characteristics of Seoul, which has a lot of traffic, it is difficult to respond quickly with a snow removal method that relies on snow removal vehicles. Therefore, it is necessary to develop an IoT based eco-friendly snow removal system that can respond to unexpected heavy snow in winter. In this study, the low temperature operation and snow removal performance of the IoT road condition snow removal detector and the snow removal system using CNT and PCM are evaluated in the climatic environment chamber. METHODS : To make artificial snow, it consists of an climatic environment chamber that can simulate a low temperature environment and equipment that can supply compressed air and cold water. Depending on the usage characteristics of the climatic environment chamber, use an air-water type snow maker. In order to make artificial snow, wet temperature, which takes into account the actual air temperature and the amount of moisture in the air, acts as the most important variable and is suitable for making snow, below –1.5 ℃. The lower the water temperature, the easier it is to freeze, so the water source was continuously supplied at 0 ℃ to 4 ℃. One of the two different pipes is connected to the water tank to supply water, and the other pipe is connected to the compressor to supply high-pressure air. Water is dispersed by compressed air in the form of many small droplets. The sprayed microscopic water particles freeze quickly in the low temperature environmental climatic chamber air and naturally fall to the floor, forming snow. Based on the KS C IEC 60068-2-1 cold resistance test standard, an integrated environmental test procedure was prepared to apply to IoT-based snow removal systems and performance evaluation was performed accordingly. The IoT based eco-friendly snow removal system is needed to in winter, so visual check and inspect the operation at the climatic chamber before setting up it to the actual site. In addition, grid type equipment was manufactured for consistent and reliable snow removal performance evaluation under controlled environmental conditions. RESULTS : The IoT-based eco-friendly snow removal system normally carried out the task of acquiring data and images without damaging the appearance or freezing in a low temperature environment. It showed clear snow removal performance in areas where PCM and CNT heating technology were applied to the concrete slab. This experiment shows that normal snow removal tasks can be carried out in low temperature environments in winter. CONCLUSIONS : The integrated environmental test procedures and grid type evaluation equipment are applied to low temperature operation and snow removal performance evaluation of snow removal systems. In the climatic environment chamber, where low temperature environments can be simulated, artificial snow is created regardless of the season to derive quantitative experimental results on snow removal performance. PCM and CNT heating technology showed high snow removal performance. The system is expected to be applied to road site situations to preemptively respond to unexpected heavy snow in winter.

Conventional aquaculture faces declining productivity, shifting to recirculating aquaculture system (RAS), known for minimizing water usage and maintaining consistent water temperatures for year-round fish growth. Rainbow trout (Oncorhynchus mykiss), a globally important cold-water species and the third most farmed fish in inland waters of Korea, valued for its fecundity and rapid growth. Dissolved oxygen, an important environmental factor affecting fish production and economics, highlights the need for smart aquaculture practices. Since 2018, the rise of intelligent aquaculture platforms, incorporating information and communications technology (ICT), emphasizes the essential role of RAS implementation. This eight-week study aimed to determine the optimal dissolved oxygen concentration for rainbow trout in RAS, utilizing a device for continuous monitoring, control and record. Dissolved oxygen concentrations were set at 5-6 mg/L, 9-10 mg/L, 14-15 mg/L and 17-18 mg/L. The growth rate significantly decreased at 5-6 mg/L, with no significant differences in other experimental groups. In hematological analysis, growth hormone (GH) was significantly highest at 5-6 mg/L, followed by 9-10 mg/L while Insulin-like growth factor-1 (IGF-1) was significantly lowest at 5-6 mg/L. In conclusion, the optimal dissolved oxygen concentration for rainbow trout in RAS is approximately 9-10 mg/L. Higher concentrations do not contribute to further growth or profitability.

A new annual dose evaluation system called E-DOSE has been developed. The system is based on the methodology of the previous version, K-DOSE60, which uses the dose evaluation methods of the International Commission on Radiological Protection (ICRP-60). However, E-DOSE is coded in ABAP to be compatible with the KHNP’s enterprise resource planning (ERP) system, SAP. This allows E-DOSE to use the real-time data from SAP, which minimizes the need for user intervention. The socio-environmental data, which was previously managed by the staff of each plant sites, can now managed in the system in a centralized manner. This is a significant improvement over the previous system, as it reduces the risk of errors and makes it easier to track and manage data. The system also automatically generates the reports required by regulations. EDOSE is expected to minimize the occurrence of human errors in preparing and managing the input data. This is because the system uses the data from SAP, which is less prone to errors than manually entered data. Additionally, the automatic generation of reports reduces the risk of errors in report preparation. E-DOSE is also expected to improve work efficiency. This is because the system automates many of the tasks involved in annual dose evaluation, such as data entry, calculation, and report generation. Overall, E-DOSE is a significant improvement over the previous annual dose evaluation system. It is more efficient, accurate, and user-friendly.

Recently, BNS (Best System) developed a system for evaluation and classification of soil and concrete wastes generated from nuclear power plant decommissioning. It is composed of various modules for container loading, weight measurement, contamination evaluation, waste classification, stacking, storage and control. The contamination evaluation module of the system has two sub modules. One is for quick measurement with NaI (Tl) detector and the other is for accurate measurement with HPGe detector. The container used at the system for wastes handling has capacity of 100 kg and made of stainless steel. According to the measurement result of Co-60 and Cs-137, the waste is classified as waste for disposal or waste for clearance. Performance of the system was demonstrated using RM (Reference Material) radiation source. This year, necessity of system improvement was suggested due to revised operation requirements. So, the system should show throughput of more than 1 ton/hr and Minimum Detectable Activity (MDA) of less than 0.01 Bq/g (1/10 of criteria for regulatory clearance) for Co-60 and Cs-137. And soil waste become main target of the system. For this, the container used for soil waste handling should have capacity of 200 kg. As a result, material for the container need to be changed from stainless steel to plastic or FRP (Fiber Reinforced Plastics). And large area detector should be introduced to the system to enhance processing speed of the system. Additionally, container storage rack and conveyor system should be modified to handle 200 kg capacity container. Finally, moving path of the container will be redesigned for enhanced throughput of the system. In this paper, concept development of the system was suggested and based on that, system development will be followed.

Economical radioactive soil treatment technology is essential to safely and efficiently treat of high-concentration radioactive areas and contaminated sites during operation of nuclear power plants at home and abroad. This study is to determine the performance of BERAD (Beautiful Environmental construction’s RAdioactive soil Decontamination system) before applying magnetic nanoparticles and adsorbents developed by the KAERI (Korea Atomic Energy Research Institute) which will be used in the national funded project to a large-capacity radioactive soil decontamination system. BERAD uses Soil Washing Process by US EPA (402-R-007-004 (2007)) and can decontaminate 0.5 tons of radioactive soil per hour through water washing and/or chemical washing with particle size separation. When contaminated soil is input to BERAD, the soil is selected and washed, and after going through a rinse stage and particle size separation stage, it discharges decontaminated soil separated by sludge of less than 0.075 mm. In this experiment, the concentrations of four general isotopes (A, B, C, and D which are important radioisotopes when soil is contaminated by them.) were analyzed by using ICP-MS to compare before and after decontamination by BERAD. Since BERAD is the commercial-scale pilot system that decontaminates relatively large amount of soil, so it is difficult to test using radioactive isotopes. So important general elements such as A, B, C, and D in soil were analyzed. In the study, BERAD decontaminated soil by using water washing. And the particle size of soil was divided into a total of six particle size sections with five sieves: 4 mm, 2 mm, 0.850 mm, 0.212 mm, and 0.075 mm. Concentrations of A, B, C, and D in the soil particles larger than 4 mm are almost the lowest regardless of before and after decontamination by BERAD. For soil particles less than 4 mm, the concentrations of C and D decreased constantly after BERAD decontamination. On the other hand, the decontamination efficiency of A and B decreased as the soil particle became smaller, but the concentrations of A and B increased for the soil particle below 0.075 mm. As a result, decontamination efficiency of one cycle using BERAD for all nuclides in soil particles between 4 mm and 0.075 mm is about 45% to 65 %.

Domestic nuclear power plants can affect the environment if multiple devices are operated on one site and even a trace amount of pollutants that may affect the environment after power generation are simultaneously discharged. Therefore, not only radioactive substances but also ionic substances such as boron should be discharged as minimally as possible. We adopted pilot CDI and SD-ELIX sytem to separating and concenrating of boron containing nulcear power plant discharge water. The boron concentration of the initial inflow water tended to decrease over time. The water quality of concentrated water also reached its peak until the initial 60 minutes, but tended to decrease in line with the decrease in the inflow water concentration. The boron removal rate was in the range of 85 to 99% with respect to the initial boron concentration of 15 to 25 mg/L. On the other hand, performance degradation due to the use of electrochemical modules is also observed, and regeneration through low ion-containing water cleaning effective. We shortened processing time by considering the optimal flow rate conditions and conductivity conditions and converting electrochemical modules into series or parallel.