동아시아 공급망 경제를 분석하여 공급망의 효율적인 운영방안과 새로운 동아시아 공급망경제의 필요성을 제시하고자 한다. 동아시아는 육로를 이용한 동아시아의 공급 망이 구축될 경우에 시너지와 커다란 동아시아 국가별 이익지대가 존재한다. 본 연구는 시나리오 방법을 이용하여 동아시아 경제의 이익지대를 분석하여 새로운 동아시아시대를 준비하고, 동아시아 국가들의 공동의 번영을 도모하는 데 있다.

인체내 활성산소(Reactive oxygen species : ROS)의 축적은 산화적 스트레스가 발생하게 됨으로서 질병을 유발시키는 원인이 되고 있다(Reiter, 1995; Halliwell et al., 1992; 조 등, 2008). 활성산소종이 정상적으로 소거되지 않았을 때는 자유라디칼에 의해 다른 질병의 원인이 되기도 하고, 식품의 산패와 독성물질의 생성 등으로 인체에 유해 작용을 하는 것으로 보고되고 있다(Halliwell,1996; Ayranci et al., 2008). 이에 따라 활성산소종의 제거 및 생체 내 항산화 방어 시스템의 증진에 대한 관심이 높아지고 있으며, 활성 산소를 억제시킬 수 있는 안전한 대체 물질 개발이 요구되고 있는데(이등, 2010; Ody, 1995; Choe & Yang, 1982), 합성약물이 아닌 천연물에서 그 효능을 찾는 연구가 활발히 이루어지고 있다. 식품에는 자연적으로 발생되어있는 여러 가지 항산화 능력을 가진 화합물이 함유되어있으며, 특히 페놀성 화합물은 식품 속에 널리 분포하는 2차 대사산물로 Phenolic acids (C6-C1), Coumarins (C6-C3), Flavonoids (C6-C3-C6), Tannins로 크게 4가지 그룹으로 나누어진다(Lee & Lee, 1994). Tannins 중에서 Gallic acid 및 Methyl gallate, Ethyl gallate, Acertannin, Polygagallin, Ginnalin B,C, gallicin 등의 화합물은 강력한 항산화 활성과 항균활성 및 항암효과도 있는 것으로 알려져 있다(Choi, 2005). 최근 in situ 수준에서 생산된 폴리페놀의 기능성에 대한 관심이 집중되고 있는 현실에서 본 연구는 버섯류에서 생산 가능한 폴리페놀 화합물의 구조 결정 및 기능성에 대한 기초자료 확보를 목적으로 수행되었다. PDB배지에 Gallic acid (GA) 및 Methyl gallate (MG)를 0.1～0.5%의 농도로 첨가하여 배지를 조제하고, PDA에서 배양된 표고균주(저온성, 산조 502호)를 접종하여 일정기간 배양 후 균사체와 배양여액을 분리하였다. 이로부터 제조된 균사체와 배양여액은 냉동건조 한 다음 화학적 특성을 분석하였다.

Nano-sized SnO2 thick films were prepared by a screen-printing method onto Al2O3 substrates. The sensing characteristics were investigated by measuring the electrical resistance of each sensor in a test box as a function of the detection gas. The nano-sized SnO2 thick film sensors were treated in a N2 atmosphere. The structural properties of the nano SnO2with a rutile structure according to XRD showed a (110) dominant SnO2 peak. The particle size of SnO2:Ni nano powders at Ni 8 wt% was about 45 nm, and the SnO2 particles were found to contain many pores according to the SEM analysis. The sensitivity of the nano SnO2-based sensors was measured for 5 ppm CH4 gas and CH3CH2CH3 gas at room temperature by comparing the resistance in air with that in the target gases. The results showed that the best sensitivity of SnO2:Ni and SnO2:Co sensors for CH4 gas and CH3CH2CH3 gas at room temperature was observed in SnO2:Ni sensors doped with 8 wt% Ni. The response time of the SnO2:Ni gas sensors was 10 seconds and recovery time was 15 seconds for the CH4 and CH3CH2CH3 gases.

The purpose of this study was to investigate the status of domestic and foreign power blogs that serve as professional source of information and to clarify the difference of the criteria for the certification and selection of power blogs. The study also analyzed the configuration of contents and the characteristic of categories of the power blogs. Eleven domestic blogs were examined, of which ten were certified as power blogs on several portal sites and one blog was operating in English. Furthermore twelve foreign blogs were examined, of which ten blogs were selected from the graded list of www.alexa.com for the Fashion Power Blog TOP 20 adopted on www.telegraph.co.uk in 2009, and two noticeable blogs were selected additionally. Data were analyzed by both theoretical and exploratory studies. The exploratory study was conducted by fourteen majors, who took interest in the blogs and were divided into two groups to look at the domestic and foreign sites, from 12 October to 12 November in 2010. The types of blogs were classified by frequency analysis of interactivity, interest provision, information provision and purchase capability. The investigators checked the type of the contents of each blog and the frequencies were used for the classification type. The analysis showed that the frequencies were in the order of information provision, followed by interest provision, and purchase capability for foreign blogs, while interest provision was followed by information provision for domestic blogs. Interactivity, interest provision, information provision and purchase capability were generally reflected in foreign blogs. Rather than interest provision and information provision, however, interactivity and purchase capability were reflected relatively weakly in domestic blogs.

The purpose of this study was to develop slacks patterns for middle-aged abdomen-obese adult males by using the 3D virtual-twin and virtual-garment simulation system. The criteria for subjects in this study were males who had over 25kg/m2 of BMI, over 90cm of waist, and over 0.90 of WHR. A total of 211 adult males who met these criteria were enrolled. The results were as follows: first, a new slacks pattern considerate of abdomen-obese men was development. The basic numerical formula were as follows: front and back hip girth H/4+3.5, front waist girth W/4+1+0.5, back waist girth W/4+1－0.5, front crotch extension H/16, back crotch extension H/8－0.5, front pleats amount 2.7, and back dart amount 1.5. Second, according to the results of the new slacks patterns appearance evaluation, the new slacks pattern scored more highly than the existing pattern in silhouette and ease amount, confirming that the new slacks pattern is appropriate for the abdomen-obese men. Also, the new slacks pattern was evaluated allowing proper space length of waist, abdomen and hip. Virtual models of production through data from a 3D body scan, pattern draft and virtual garment digital program were applied to a prototypic design method in order to enhance the fitness of ready-made garments. The use of the virtual twin made it impossible to comprehend the appearances and ease correspondent to motions. In order to evaluate wearing fitness, therefore, the system should be improved so as to change arm positions and perform various motions.

Traditional culture could be a wonderful source of inspiration for creative design. Tteoksal, the stamps used for making decorative patterns on traditional rice-cakes, have been used and passed on to generations to show the emotions of our ancestors. Numerous traditional patterns found in Tteoksal can be used to better understand and transmit tradition in modern ways. The purpose of this study was to develop fashion cultural products with a modern sensibility by understanding the origin, types and characteristics of Tteoksal and its patterns. The method of this study was through considering the proceeding studies and the references published by a specialist and museums having some information about further knowledge on Tteoksal. In line with the aforementioned study, neckties, eco-friendly bags and pouches were developed as fashion goods. Among the Tteoksal's patterns selected were lotus, bats, 樂letters and complex patterns. Using a computer graphic software program such as Adobe Illustrator CS5, archetypes of patterns were traced as vector graphics, and two design motives were developed in every pattern. The patterns were developed into two types: one was a basic pattern faithful to a basic motive pattern, and the other was a varied type that was changed and applied. The fashion products were developed as two styles for basic and varied patterns for neckties, eco-friendly bags and pouch items. Twelve products were made for each pattern, which totals 48 unique products. In conclusion, the study could be a critical step to better understand the traditional culture and its influence to the patterns applied to modern fashion design.

We measured indoor, outdoor, and personal exposure concentrations of ozone (O₃) at 54 households in Gwangyang from June to September, 2009. The results are as follows. The concentration of ozone in outdoor, 16.53±5.72 ppb, was observed two times higher than the concentration of ozone in indoor, 8.22 ± 4.60 ppb. The similar arithmetic average ozone were obtained in exposed and controlled areas, 15.16 ± 1.45 ppb and 15.25 ± 1.94 ppb, respectively. The ozone concentration of an individual smoker was 24.89 ± 7.11 ppb, which was higher than that of a non-smoker, 21.01 ± 11.79 ppb. The indoor occupant density elevated ozone concentrations. The relatively low concentration of ozone was observed in a house with air conditioner (8.59 ± 4.04 ppb) than a house without the unit(10.07 ± 6.43 ppb).

제주도 한라산에 위치한 국내 최대규모의 고산습지인 숨은물벵뒤 습지의 Alphaproteobacteria와 Gammaproteobacteria강에 속하는 세균 종의 다양성을 조사하였고, 신분류군 후보 균주 19종을 확보하였다. 신종후보 균주의 16S rRNA 유전자 염기서열을 분석하였을 때 표준균주와 98.7% 미만의 유사도를 보이는 균주들을 신종후보균주로 간주하였다. 총 19종의 세균이 Alphaproteobacteria와 Gammaproteobacte

제주도 한라산의 숨은물벵뒤 습지는 여러 다른 생태계에 비해 접근이 용이하지 않아 생물다양성이 높다고 여겨져 왔으나, 세균의 다양성과 새로운 종에 대한 보고는 전혀 이루어지지 않았다. 본 연구에서는 제주도 한라산의 고산 습지인 숨은물벵뒤 습지에서 담수 및 토양시료를 채취하여 Bacteroidetes, Firmicutes, Actinobacteria문에 속하는 세균을 분리하였다. 분리된 세균 중 위의 3개의 문에 속하는 균주의 16S rRNA 유전자 염기서

Estimating optimum hardware capacity of an e-learning system is very important process to grasp reasonable size of designing technique architecture and budget during step of ISP(information strategic planning) and development. It hugely influences cost an

Glutamate-induced oxidative injury contributes to neuronal degeneration in many central nervous system (CNS) diseases, such as Parkinson’s disease, Alzheimer’s disease, epilepsy and ischemia. Inducible heme oxygenase (HO)-1 acts against oxidants that are thought to play a role in the pathogenesis of these diseases. The EtOH extracts of Viola mandshurica (NNMBS274), Viola patrinii (NNMBS275) and Viola papilionacea Pursh (NNMBS276), origin plants of Violae Herba, showed the potent neuroprotective effects on glutamate-induced neurotoxicity. Among them, NNMBS275, the extract of V. patrinii possessed the protective effects against glutamate toxicity by inducing the expression of heme oxygenase (HO)-1 in the mouse hippocampal HT22 cells. These results suggest that extracts of V. patrinii could be the effective candidates for the treatment of ROS-related neurological diseases. Furthermore, it is suggested that the protective effects of V. patrinii extract due to inducing the expression of HO-1 asAs the exfoliated keratinocytes (EKs) in oral mucosa are aging and degenerating cells, of which cytoplasms are almost replaced by cross-linked keratin materials. Consequently, the EKs become apoptotic with nuclear lysis. A question is arisen what is the biological role of these EKs in oral cavity? Are they simply degrading as aging keratinocytes or do they have some essential function still remained in the exfoliated status? The buccal smear samples from ten healthy adult subjects were observed under scanning electron microscope. On the outer surface of the EKs the features of bacterial adhesion were explored. The microorganisms attached on the surface of EKs were much deformed, shrunken and teared. Only a few microorganisms were found on the EK surface, aggregated focally. The attached microorganisms were gradually fused on the cell membrane of EKs, and subsequently endocytosed. Resultantly, many round endocytotic concave cavities similar size to the cocci were remained on the surface of EKs similar to the sequels of caveolae endocytosis. These data indicate that the degenerating EKs can actively engulf microorganisms attached on their cell surface via the processes of caveolae endocytosis. Therefore, it is presumed that the oral EKs still play a role for endocytotic scavenging of oral microorganisms using the denatured cell bodies themselves, which become highly adherent to oral microorganisms and still function for caveolae endocytosis in mixed saliva environment. an antioxidant/cytoprotective target

본 연구는 국내산 침엽수로부터 천연 항균화합물 개발을 목표로 미송 및 편백으로부터 추출물을 확보 하여 푸른곰팡이병의 원인균인 Trichoderma spp. 5종을 대상으로 항균활성을 테스트하고 GC/MS를 이 용하여 항균화합물을 탐색하였다. 미송 추출물은 Trichoderma spp.에 대해 1,000 ppm에서 저해 활성을 나타냈으며, 4,000 pp에서는 T. viride>T. harzianum>T. aggressivum 순으로 70.1, 67.3, 64.7% 의 높은 항균활성을 나타냈다. 편백 추출물도 1,000 ppm에서 항균활성을 나타냈고 4,000 ppm에서 T. viride>T. harzianum>T. aggressivum 순으로 63.2, 59.3, 59.1%의 높은 항균활성을 나타냈다. 그러나 1,000 ppm의 미송추출물과 1,000 ppm의 편백추출물을 각각 9:1, 8:2, 6:4, 2:8 (w/w) 비율의 혼합제 제로 만들어 Trichoderma spp.에 처리하였을 때 미송추출물 1,000 ppm 및 편백추출물 1,000 ppm 각 각의 단일추출물보다 낮은 항균활성을 나타냈다. Trichoderma spp. 5종에 대해 높은 항균활성을 나타 내는 미송추출물에서는 2-Isopropoxy-ethylamine 46.5%, epifluorohydrin 8.6%, trans-2,3-Dimethyloxirane 7.6%, (IR)-(-)-Myrtenal 6.0%, 2-Methoxy-4-Vinylphenol 3.9%, benzaldehyde 2.8%가 함유되어 있었고, 편백추출물에서는 α-Terpinenyl acetate 14.9%, Sabinene 10.9%, dl-Limonene 9.6%, α-Terpinolene 7.5%, α-Pinene 7.1%가 함유된 것이 확인되었다.

Ti-6Al-4V ELI (Extra Low Interstitial) alloy has been widely used as an alternative to bone due to its excellent biocompatibility. However, it still has many problems, including a high elastic modulus and toxicity. Therefore, nontoxic biomaterials with a low elastic modulus should be developed. However, the fabrication of a uniform coating is challenging. Moreover, the coating layer on Ti and Ti alloy substrates can be peeled off after implantation. To overcome these problems, it is necessary to produce bulk Ti and Ti alloy with hydroxyapatite (HA) composites. In this study, Ti, Nb, and Zr powders, which are biocompatible elements, were milled in a mixing machine (24h) and by planetary mechanical ball milling (1h, 4h, and 6h), respectively. Ti-35%Nb-7%Zr and Ti-35%Nb-7%Zr-10%HA composites were fabricated by spark plasma sintering (SPS) at 1000˚C under 70MPa using mixed and milled powders. The effects of HA addition and milling time on the biocompatibility and physical and mechanical properties of the Ti-35%Nb-7%Zr-(10%HA) alloys have been investigated. Ti2O, CaO, CaTiO3, and TixPy phases were formed by chemical reaction during sintering. Vickers hardness of the sintered composites increases with increased milling time and by the addition of HA. The biocompatibilty of the HA added Ti-Nb-Zr alloys was improved, but the sintering ability was decreased.

Plantago asiatica L. (PA), which is widely distributed in Korea, Japan and China, has traditionally been used as a popular folk medicine for the treatment of liver diseases. A variety of activities of PA was reported, that is hepatoprotective, anti-inflammatory, anti-glycation and anti-oxidant effect. Ferric nitrilotriacetate (Fe-NTA) is a potent nephrotoxic agent and has been reported to induce renal proximal tubular necrosis. In the present study, pretreatment with PA extract (PAE) in Wistar rat followed by Fe-NTA i.p. treatment (13.5 mg Fe/kg body weight) was performed to detect the renal protective effect of PAE. Only Fe-NTA treated group showed increases in the level of serum blood urea nitrogen (BUN) and serum creatinine (Cr), and renal tissue malondialdehyde (MDA), product of lipid peroxidation. Moreover, the level of biomarkers indicate the antioxidants status, reduced glutathione (GSH), glutathione-S-transferase (GST) and glutathione reductase (GR) were decreased. However, PAE pre-treated group showed decreases in the levels of serum BUN, serum Cr and renal tissue MDA in concentration dependent manner and increases in the level of GSH, GST and GR. These results are significantly different (p < 0.05) to the other groups. Our data suggest that PAE may be used as an chemopreventive material against Fe-NTA-mediated renal oxidative stress.

목적 : DACUM 기법을 통해 작업치료사 직무를 분석하고, 현재 국내 작업치료사가 임상현장에서 수행하고 있는 주 요 책무와 작업의 중요도와 수행빈도를 제시하고자 한다. 연구방법 : 국내 작업치료사의 직무 분석을 위해 DACUM 기법을 사용하였다. 이를 위해 DACUM 위원회를 구성하 였고, DACUM 워크샵을 통해 직무분석을 시행한 후, 수도권에서 근무하고 있는 국내 작업치료사 252명을 대상으 로 설문조사를 거쳐 수행작업(task)별 우선순위를 파악하였다. 결과 : 본 연구를 통하여 작업치료사 직무의 정의와 4개의 책무(평가, 치료, 교육, 행정 및 관리), 21개의 수행작업 을 제시하였고, 각 수행작업에 대한 중요도 우선순위가 도출되었다. 전체 수행작업 중 직무분석 위원회와 설문조 사에서 각 책무에서 중요한 항목을 결정한 결과 평가책무에서는 평가결과해석, 치료 책무에서는 치료실행, 교육에 서는 환자교육과 보호자교육, 행정 및 관리에서는 문서관리로 교육을 제외한 모든 책무에서 책무의 우선순위에서 일치하였다. 하지만 수행작업에 대한 중요도는 직위, 경력, 근무 종별등 직무요인에 따라 차이가 있었다. 결론 : 본 연구 결과는 대학의 작업치료 교육과정, 분과학회의 교육과정 변경 또는 운영에 기여할 것으로 사료된다.

목적 : 자세조절과 시지각 능력은 일상생활 및 학습을 하는 데 있어 기초가 되고 이러 한 요소는 뇌성마비 아동을 치 료하는데 주된 목표가 된다. 따라서 본 연구를 통해 경직형 뇌성마비 아동에서 안구운동프로그램이 자세조절과 시 지각 능력에 미치는 영향을 알아보고자 한다. 연구방법 : 2010년 5월 1일부터 2010년 8월 31일까지 부산에 위치한 P복지관에 내원하는 만4세~8세 경직형 뇌 성마비 아동을 대상으로 하였다. 10명의 경직형 뇌성마비 아동을 무작위로 실험군과 대조군으로 각각 5명씩 배정 하였다. 실험군에게는 안구운동프로그램과 함께 일반적 작업치료를 제공하고 대조군에게는 일반적 작업치료를 시 행하였다. 안구운동 프로그램은 단속성안구운동, 이접안구운동, 추적안구운동, 전정안구운동 4가지로 구성되어 있 다. 활동 중재는 1회 40분씩 주 3회로 8주 동안 제공되었다. 중재 전∙후에 대한 평가는 대동작기능평가(GMFM), 소아균형척도(PBS), 소아뻗기검사(PRT)와 한국판시지각발달검사(K-DTVP)를 사용하였다. 결과 : 안구운동프로그램을 수행한 실험군에서는 GMFM, PBS, PRT와 시각통합을 제외한 K-DTVP 모든 하위평 가항목에서 중재 전과 후의 점수가 통계적으로 유의한 차이가 있는 것으로 나타났으나(p<.05), 대조군에서는 PRT와 K-DTVP의 눈손협응과 공간위치를 제외하고는 통계적으로 유의한 차이를 보이지 않았다. 또한 두 집단 의 평가 점수의 변화량을 비교하였을 때 모든 평가항목에서 실험군이 대조군에 비해 유의한 차이를 보여 자세조절 과 시지각 기능 향상이 대조군보다 더 좋음을 나타냈다(p<.05). 결론 : 본 연구는 경직형 뇌성마비 아동에서 안구운동프로그램 중재가 자세조절 및 시지각능력 향상에 효과적임을 시사한다.