This study was conducted to explore the potential of Pungsannamul-kong, which did not germinate from soybean to bean sprouts and was discarded, and to find out the changes in composition and bioactivity during roasting treatment. The functional effectiveness of isoflavone contents, as well as their antioxidant and antiinflammatory activities, were analyzed with Pungsannamul-kong roasted at various temperatures: 100oC (RoJP100), 120oC (RoJP120), 140oC (RoJP140), 160oC (RoJP160), and 180oC (RoJP180). The aglycone content of isoflavones was the highest (87.58 μg/g) in RoJP180 and was correlated with the increase of genistein. As the roasting temperature rose, total polyphenol content increased to 410.32 μg GAE/mg, flavonoid content to 56.04 μg QE/mg, DPPH radical scavenging activity to 76.59%, ABTS radical scavenging activity to 51.97%, and SOD-like activity to 52.63%. NO production was significantly suppressed in 500 μg/mL of all the roasted Pungsannamul-kong groups (p<0.05). TNF-α, IL-1β, and IL-6 expressions were suppressed in a concentrationdependent manner as the roasting temperature increased. Western blotting also showed that iNOS and COX-2 expression were suppressed after roasting at 180oC, confirming an anti-inflammatory effect. This study concluded that non-germinated soybeans were still valuable in terms of nutritional and functional properties. Moreover, roasting treatment increased the isoflavone content and improved physiological bioactivities such as antioxidant and anti-inflammatory activities.

The new thermal management models of linear compressors have been recently reported. These models adopt the simplified transient flow effects to shorten the excessive analysis time. Among the unsteady flow effects of the linear compressor, the effect of the gap flow between the compressor housing and the body due to the body vibration on the heat transfer performance was studied in this paper. For this study, a numerical analysis for the unsteady axisymmetric flows was performed by using CFD (Computational Fluid Dynamics). The results show that the high-speed refrigerant flows occurred in the gap between the compressor housing and the body, which contribute to increasing the heat transfer from high temperature refrigerants in the housing to the outside air. In addition, as the gap decreases, the refrigerant flow rate through the gap increases and the heat transfer rate increases as well.

본 연구에서는 경북 지역에 분포하는 소나무림을 대상으로 수관연료의 수직적 구조, 수관연료밀도를 파악하고, 여러 가지 변수를 이용한 수관층 각 부위별 연료량 추정식을 개발하고자 하였다. 본 연구 결과에 의하면, 수관층 연료의 수직적 분포 형태는 방추형으로 상대적 높이 비율 0.6~0.8 구간에 가장 많은 연료가 분포하였으며, 0.4 이하의 수관 하단부에는 주로 고사된 가지가 분포하고 0.8 이상부터 상단부로 갈수록 연료가 적어지는 형태를 보였다. 전체 수관에 대한 연료밀도는 평균 0.38kg/㎥이었으며, 이 중 산불 발생 시 쉽게 탈 수 있는 연소가능한 연료의 밀도는 0.21kg/㎥이었 다. 수관 특성 중 수관길이와 수관폭을 이용하여 수관층 연료량 추정식을 개발한 결과 조정결정계수(R2adj)의 범위는 0.56~0.79이었으며, 수관길이와 수관폭을 변수로 함께 사용하였을 경우 조정결정계수(R2adj)가 더 높은 값을 보였다. 본 연구의 결과는 임목에 대한 산불 연료적 관점에서의 다양한 정보를 제공할 뿐만 아니라, 영상자료를 활용하여 수관층 연료량을 추정하는데 활용될 수 있다.

본 연구의 목적은 모발 성장인자 관련 논문의 고찰을 통해 성장인자가 탈모에 적용되었을 때 모발의 시너지 효과를 연구하여 뷰티산업 종사자들이 전문적이고 경쟁력 있는 제품 선택의 폭을 넓힐 수 있으며 그로 인해 틈새 시장인 점판 시장의 활성화로 뷰티산업의 발전에 기여하고자 하였다. 성장 인자는 인체가 출생 시 가지고 태어나는 세포분열 활성화인자로 기능이 떨어진 세포를 자극하여 모발 성장과 모유두 세포의 세포 분열을 촉진시키며 모발 성장기를 연장시킨다. 모낭에서 발현되는 것으로 보고된 성장 인자는 섬유아세포 성장인자(bFGF, basic Fibroblast GF), 혈관내피세포 성장인자(VEGF, Vascular endothelial Growth Factor), 인슐린 유사 성장인자(IGF-1, Insulinlike Growth Factor), Noggin(모낭자극성장인자), 줄기세포증식인자 (SCF, Stem Cell Factor), 케라틴형성세포 성장인자(KGF ,keratinocyte growth factor), 간세포성장인자 (HGF, hepatocyte growth factor) 등이 있다. 이들 성장인자들은 각각 모낭과 모발의 형성을 촉진하며 모낭의 성장을 조절하고 모발의 성장기 유지에 기여하며 정상적인 성장 주기로 컨트롤 한다. IGF-1과 GH를 같이 투여하면 시너지 효과를 얻어 피부 파필라 주위의 매트릭스 세포와 결합 조직 피복(CTS)의 두께가 증가함을 알 수 있다. 프로시니아딘(포도씨 추출물)과 산사열수 추출물은 모발 성장과 모유두세포의 성장인자 유전자 발현에 유의미하다. 황칠나무 잎 추출물의 적용 시도 모유두 세포의 성장인자 유전자 발현에 유의미한 효과가 있다. 모발이 성장함에 따라 IGF-1의 발현 은 증가되고 TGF-β1의 발현은 감소되어 모유두 세포의 퇴행과 감소를 지연시켜 주는 역할을 하여 성장인자가 남성형 탈모를 지연시켜 줄 수 있다고 사료된다. 본 논문은 좀 더 편리하고 효과가 증대되는 대중적인 두피.모발관리의 한 방법인 샴푸, 트리트먼트 등의 제품을 사용하여 다양하고 전문적인 제품에 대한 긍정적인 인식과 대안을 제시 하고자 하였으며 추후 더 많은 연구를 통하여 미흡한 점이 보완되기를 바란다 .

Zinc-ion Batteris (ZIBs) are recently being considered as energy storage devices due to their high specific capacity and high safety, and the abundance of zinc sources. Especially, ZIBs can overcome the drawbacks of conventional lithium ion batteris (LIBs), such as cost and safety issues. However, in spite of their advantages, the cathode materials under development are required to improve performance of ZIBs, because the capacity and cycling stability of ZIBs are mainly influenced by the cathode materials. To design optimized cathode materials for high performance ZIBs, a novel manganese oxide (MnO2) coated graphite sheet is suggested herein with improved zinc-ion diffusion capability thanks to the uniformly decorated MnO2 on the graphite sheet surface. Especially, to optimize MnO2 on the graphite sheet surface, amounts of percursors are regulated. The optimized MnO2 coated graphite sheet shows a superior zinc-ion diffusion ability and good electrochemical performance, including high specific capacity of 330.8 mAh g−1 at current density of 0.1 A g−1, high-rate performance with 109.4 mAh g−1 at a current density of 2.0 A g−1, and remarkable cycling stability (82.2 % after 200 cycles at a current density of 1.0 A g−1). The excellent electrochemical performance is due to the uniformly decorated MnO2 on the graphite sheet surface, which leads to excellent zinc-ion diffusion ability. Thus, our study can provide a promising strategy for high performance next-generation ZIBs in the near future.

Refrigerators used in homes occupy a large portion of the power consumption. In addition, most of the power consumption of the refrigerator is used by the compressor. Therefore, it is necessary to study on the improvement of compressor efficiency to save energy. In this study, the suction system was changed to improve the efficiency of the linear compressor. For this, numerical analysis was performed by linking the 1 dimensional lumped model and the 2 dimensional axisymmetric CFD model. The numerical analysis results were also compared with the experimental results. As a result of the numerical analysis, the model with modified suction system increased EER by about 0.25% compared to the basic model, which was also confirmed by experiment.

과학적 행정을 위한 증거 기반 정책 수립과 평가에 대한 요구로 통계(데이터) 활용 중요성이 날로 강조되고 있다. 통계는 사회 전반의 현상을 수치로 제공함으로써 직관적으로 어떤 현상을 설명할 수 있도록 하며, 합리적인 의사결정을 위한 공공자원으로 설명된다. 이러한 특성으로 통계는 정부 정책 결정 및 각종 현상의 연구․분석 등에 기초자료이자 근거자료로 널리 활용되고 있으나 그 중요성에 비해 통계의 역할은 제한적인 수준이다. 이는 현재 개방된 통계가 단순 결과 요약 자료 수준이며 공급자 위주로 생산되어 수요자 관점에서 가치 창출을 위한 수단으로는 부족하다는 의미이며, 본 연구에서는 이러한 문제 보완을 위해 현재 제공되는 통계 항목 외에 정책이나 연구에 다양하게 활용할 수 있는 추가 속성을 탐색했다. 연구에 활용한 기준 통계자료는 해양경찰청에서 발간하는 「해상조난사고 통계 연보」이며, 해양경찰에서 작성하는 선박사고 상황보고서 텍스트 분석을 통해 추가할 수 있는 속성들을 도출했다. 텍스트 분석을 통해 도출된 56개 속성에 대해 데이터를 수집하고 EDA를 수행한 결과, 유의확률(p-value < .05)을 만족하는, 상관계수 0.7 이상의 강한 상관관계가 있는 속성 조합 18개와, 중간 정도의 상관관계(0.4 이상 0.7 미만)를 가지는 속성조합 70개, 총 88개의 조합을 발굴할 수 있었다. 더불어 EDA를 통해 발견된 추가 속성을 정책적으로 활용하기 위해 수난대비기본계획 세부 전략별 키워드 분석을 실시하고, 키워드와 EDA 도출 속성 간 매칭작업을 통해 속성의 활용 가능 여부를 검토했다.

The purpose of this study was to evaluate microbiological contamination of knives and cutting boards in child-care centers. Materials used in this study were swabbed of cutting boards and knives (blade, handle of knife, and joint of handle and blade) in 129 child-care centers. Mean values of total aerobic bacteria of swabs of knives and cutting boards were 1.7±0.7 log cfu/100 cm2 and 1.7±0.9 log cfu/100 cm2, respectively. Contamination levels of coliform bacteria from knives and cutting boards were 1.5±0.6 log cfu/100 cm2 and 1.7±0.8 log cfu/100 cm2, respectively. Comparing microbiological contamination levels of knives and cutting boards according to type and size of child-care centers, there was no significant difference. Bacillus cereus was detected in knife handles and cutting boards. Diarrhea-type toxin gene (entFM) was detected in B. cereus isolates. Antibiotic resistance tests showed that B. cereus was resistant to β-lactam antibiotics. To reduce microbiological contamination levels of knives and cutting boards in child-care centers and prevent food poisoning from bacteria contamination, continuous education by children's food-service management center is needed for sterilization and disinfection of knives and cutting boards.

한라산 구상나무 군락지에서 구과 해충의 발생 현황을 파악하기 위하여 2019년 8-10월에 3개 지역의 4개 조사구에서 구과 117개를 수집하여 생육상에서 우화시킨 후 출현종과 개체수를 확인하였다. 지역별 구과 해충의 피해율 조사를 위해 4개 조사구에서 93그루 1,235개 구과의 구과 해충 피해를 확인하였다. 조사 결과, 채집된 117개 구과에서 솔알락명나방 233개체, 구상애기잎말이나방 101개체, 똥파리 4개체가 확인되었다. 구과 당 평균 개체수는 솔알락명나방 1.99, 구상애기잎말이나방은 0.86개체로 솔알락명나방이 2배 이상 많은 것으로 나타났다. 그리고 한라산 4개 조사구 전체 구상나무 구과의 평균 피해율은 49.7에서 80.1%로 조사구별 차이를 보였다. 또한, 구과 피해율은 수목 당 구과 수가 많을수록, 피해 구과에서 우화하는 구과해충 수는 구과의 크기가 클수록 증가하는 것으로 나타나 본 연구에서 확인된 구과 해충은 수목 당 구과 수가 많으면서 상대적으로 큰 구과를 갖는 구상나무를 선호할 것으로 예상되었다.

Purpose: This study examines the effects of clinical nursing simulation education program based on problem-based learning (S-PBL) on clinical reasoning, confidence in handover reports, confidence in nursing performance, and simulation effectiveness in nursing students. Method: We used a one-group pretest-posttest design. The participants were 4th-year university nursing students who had taken a core clinical nursing practice, and 90 students participated in the S-PBL program. Data were collected before and after the S-PBL program and analyzed using descriptive statistics and paired t-tests. Results: The S-PBL program significantly increased clinical reasoning, confidence in handover reports, and confidence in nursing performance. More than 90% of students were satisfied with the education program and the simulation education effectiveness was 2.54 on a 3-point Likert scale. Conclusion: The S-PBL program could be useful in clinical nursing education for nursing students seeking to become clinical nurses. It is necessary to develop various S-PBL programs and apply them to the curriculum.

17β-estradiol (E2)는 난소로부터 방출되는 호르몬으로 가정 및 축산 오폐수에 포함되어 환경으 로 지속적으로 유출된다. E2는 높은 에스트로겐 활성을 가지고 있어 갑각류의 발달과 생식에 영향을 미치는 내분비계교란물질로 알려져 있다. 갑각류의 발달은 탈피호르몬(ecdysteroid)의 신호 전달 과정에 의해 이루어지지만 E2가 소형 갑각류의 탈피호르몬 경로 유전자를 어떻게 조 절하는지에 대한 연구는 매우 미흡하다. 본 연구에서는 기수산 물벼룩 Diaphanosoma celebensis 에서 E2에 대한 급성 독성 시험을 통해 24-h LCx 값을 도출하였고, E2 노출에 따른 탈피호르몬 경로에 관여하는 7개의 유전자(CYP314a1, EcRA, EcRB, USP, ERR, Vtg, VtgR)의 시간별 발현 변 화를 quantitative real time polymerase chain reaction (qRT-PCR)을 이용하여 분석하였다. D. celebensis의 24-h LC50 값은 9.581 mg/l (95% C.I.: 7.697~11.927 mg/l), 24 h-LC10 값은 4.842 mg/l (95% C.I.: 3.683~6.366 mg/l)로 나타났다. CYP314a1, EcRA, USP, VtgR 유전자의 발현이 12시간 또는 24시간에 유의하게 증가하는 양상을 보였다. 이러한 결과는 E2가 D. celebensis의 탈피호 르몬 경로에 관련하는 유전자의 발현을 조절함으로써 탈피와 생식에 영향을 미칠 수 있을 것 임을 시사한다. 본 연구는 소형 갑각류에서 내분비계교란물질이 탈피 경로에 미치는 영향에 대한 분자 기전을 이해하는데 도움이 될 것이다.

The most important thing to successfully restore an oak forest is finding suitable climatic conditions and topographic factors for the oak species to be introduced. In this study, in order to find suitable environmental conditions for the five dominant oak trees on the Korean Peninsula, we carried out analysing the information on the location of forest vegetation on the Korean Peninsula. The range of annual mean temperature of the five oak trees was narrow in the order of Q. mongolica (7.7~14.3°C), Q. variabilis (9.2~13.8°C), Q. acutissima (10.5~14.3°C), Q. serrata (11.4~13.7°C), Q. aliena (11.0~12.9°C). The range of annual precipitation of oaks was narrow in order of Q. mongolica (1072.7~1780.9 mm), Q. variablis (1066.6~1554.9 mm), Q. acustissima (1036.5~1504.8 mm), Q. serrata (1062.6~1504.7 mm). The range of altitude was in order of Q. mongolica (147~1388 m), Q. serrata (93~950 m), Q. variabilis (90~913 m), Q. acustissima (60~516 m), Q. aliena (55~465 m). The range of slope was in the order of Q. mongolica (8~56°), Q. variabilis (5~52°), Q. serrata (11~45°), Q. aliena (15~38°), Q. acustissima (16~37°). These results are considered to be very useful in the case of ecological restoration using deciduous oak trees on the Korean Peninsula.

In this paper, the hybrid prefabricated retrofit method is suggested and examined. Six specimens were manufactured in order to evaluate their flexural performance of RC beams. Test parameters include the added beam depth, the thickness of bottom plate, the number of the steel plate with openings. The effects of these parameters on the flexural performance of reinforced concrete beams were examined. The load-deflection behavior and modes of cracks are presented from the test results. At the test result, the flexural capacity and the ductility of the hybrid prefabricated retrofit method was increased satbly. Also, comparing the flexural performance of RC beam and retrofitted RC beams, it was increased that the flexural strength is about 3.3 times, the ductility is about 2.55 times, and energy dissipation capacity is about 7.34 times.

In this study, a tuned mass damper(TMD) was installed to control the displacement response to earthquakes by generalizing to six analysis models according to the shape of the upper structure based on the case of various large spatial structures around the world. The six analysis models are ribbed type, latticed type, elliptical type, gable type, barrel type, and stadium type composed of 3D arch trusses. In this paper, ribbed type, latticed type and elliptical type were analyzed. The mass of each TMD was set to 1% of the total structural mass. Result of analyzing the optimal number and position of the analysis model, the displacement response control was the most excellent in the model with 6 and 8 TMDs, and the displacement response decreased in most cases. The displacement response control was better with installing the TMD at the edge point than focusing the TMD at the center of the analysis model. However, when 10 or more TMDs are installed or concentrated in the center, large loads intensively act on the structure, resulting in increased displacement. Therefore, although it is slightly different depending on the shape, it is judged that the displacement response control is the best to install 6 and 8 TMDs at the close to the edge point.

In this study, a tuned mass damper(TMD) was installed to control the displacement response to earthquakes by generalizing to six analysis models according to the shape of the upper structure based on the case of various large spatial structures around the world. The six analysis models are ribbed type, latticed type, elliptical type, gable type, barrel type, and stadium type composed of 3D arch trusses. In this paper, ribbed type, latticed type and elliptical type were analyzed. The mass of each TMD was set to 1% of the total structural mass. Result of analyzing the optimal number and position of the analysis model, the displacement response control was the most excellent in the model with 6 and 8 TMDs, and the displacement response decreased in most cases. The displacement response control was better with installing the TMD at the edge point than focusing the TMD at the center of the analysis model. However, when 10 or more TMDs are installed or concentrated in the center, large loads intensively act on the structure, resulting in increased displacement. Therefore, although it is slightly different depending on the shape, it is judged that the displacement response control is the best to install 6 and 8 TMDs at the close to the edge point.