The purpose of this study is to propose a specialized clothes-sizing system for elderly (aged 60~79) obese women satisfying the following conditions based on the data from the fifth Korean Agency for Technology and Standards (2004): a Rohrer's index of over 1.6, a BMI of over 25, and a WHR of over 0.85. The lower bodies of elderly obese women tends to be shorter and wider than average. Particularly, their torsos from the chest to the waist tend to be more obese than other areas. According to the KS standards, the clothes-sizing system sets up its size intervals as follows: 5cm in stature, 5cm and 3cm in bust, 3cm in waist, and 3cm in hip. Based on the dualistic distribution of each section, the names of the sections indicating high distribution are suggested. For suit tops, 11 sizes are selected as distributed in the 145-155cm stature section and 91-103cm bust section. For casual tops, nine sizes are selected as distributed in the 145-155cm stature section and 90-105cm bust section. For bottoms, 11 sizes are selected as distributed in the 82-97cm waist section and 91-97cm hip section. According to the KS standards, detailed sizes are suggested in the division of basic and reference areas.

Chronic/cyclic neutropenia, leukocyte adhesion deficiency syndrome, Papillon-Lefèvre syndrome, and Chédiak-Higashi syndrome are associated with severe periodontitis, suggesting the importance of neutrophils in the maintenance of periodontal health. Various Toll-like receptor (TLR) ligands are known to stimulate neutrophil function, including FcR-mediated phagocytosis. In the present study, the effect of TLR2 activation on the non-opsonic phagocytosis of oral bacteria and concomitant production of reactive oxygen species (ROS) by human neutrophils was evaluated. Neutrophils isolated from peripheral blood were incubated with Streptococcus sanguinis or Porphyromonas gingivalis in the presence of various concentrations of Pam3CSK4, a synthetic TLR2 ligand, and analyzed for phagocytosis and ROS production by flow cytometry and chemiluminescence, respectively. Pam3CSK4 significantly increased the phagocytosis of both bacterial species in a dose-dependent manner. However, the enhancing effect was greater for S. sanguinis than for P. gingivalis. Pam3CSK4 alone induced ROS production in neutrophils and also increased concomitant ROS production induced by bacteria. Interestingly, incubation with P. gingivalis and Pam3CSK4 decreased the amounts of ROS, as compared to Pam3CSK4 alone, indicating the possibility that P. gingivalis survives within neutrophils. However, neutrophils efficiently killed phagocytosed bacteria of both species despite the absence of Pam3CSK4. Although P. gingivalis is poorly phagocytosed even by the TLR2-activated neutrophils, TLR2 activation of neutrophils may help to reduce the colonization of P. gingivalis by efficiently eliminating S. sanguinis , an early colonizer, in subgingival biofilm.

Background: Prone hip extension (PHE) can be performed to measure the lumbopelvic motor patterns and motions. Imbalances in lumbopelvic muscle activity and muscle weakness can result in instability including pain in lumbopelvic region. The posterior oblique sling (POS) muscles contribute to dynamic lumbopelvic stability. In addition, POS are anatomically aligned with the trapezius muscle group according to shoulder positions. Objects: This study compared the electromyography (EMG) activity of POS and pelvic compensations during PHE with and without pre-activation of lower trapezius muscle (lowT). Methods: Sixteen healthy males were recruited. PHE was performed in randomized order: PHE with and without lowT pre-activation. Surface EMG signals were recorded for biceps femoris (BF), gluteus maximus (GM) (ipsilateral), lumbar multifidus (MF) (bilateral), and the lowT (contralateral). An electromagnetic tracking motion analysis was used to measure the angle of pelvic rotation and anterior tilting. Results: The ipsilateral GM and bilateral MF EMG amplitudes were greater during PHE with lowT pre-activation compared to PHE without lowT pre-activation (p<.05). The BF amplitude during PHE without lowT pre-activation was significantly greater than that during PHE with lowT pre-activation (p<.05). The angles of pelvic rotation and anterior tilting during PHE with lowT pre-activation were significantly smaller compared to PHE without lowT pre-activation (p<.05). Conclusion: PHE with lowT pre-activation, which is aligned with the POS, showed more increased MF and GM muscular activity with smaller lumbopelvic compensations in rotation and anterior tilting compared to PHE without lowT pre-activation.

The purpose of this study was to investigate the effects of visual electromyography (EMG) biofeedback on the EMG activity of the lower trapezius (LT), serratus anterior (SA), and upper trapezius (UT) muscles, the LT/UT and SA/UT EMG activity ratios, and the scapular upward rotation angle during scapular posterior tilting exercise (SPTE). Twenty-four subjects with round-shoulder posture participated in this study. The EMG activities of the LT, SA, and UT were collected during SPTE both without and with visual EMG biofeedback. The scapular upward rotation angle was measured at the baseline, after SPTE without visual EMG biofeedback, and after SPTE with visual EMG biofeedback. The LT, SA, and UT EMG activities, and the LT/UT and SA/UT EMG activity ratios were analyzed by paired t-test. The scapular upward rotation angle was statistically analyzed using one-way repeated analysis of variance. If a significant difference was found, a Bonferroni correction was performed (p=.05/3=.017). The EMG activities of LT and SA significantly increased, and the EMG activity of UT significantly decreased during SPTE with visual EMG biofeedback compared to SPTE without visual EMG biofeedback (p<.05). In addition, the LT/UT and SA/UT EMG activity ratios significantly increased during SPTE with visual EMG biofeedback compared to SPTE without visual EMG biofeedback (p<.05). Significant increases were found in the scapular upward rotation angle after SPTE without and with visual EMG biofeedback compared to baseline (p<.017), and no significant differences were observed in the scapular upward rotation angle between SPTE without and with visual EMG biofeedback. In conclusion, SPTE using visual EMG biofeedback may be an effective method for increasing LT and SA activities while reducing UT activity.

This study analyzed the body-type characteristics of 340 old-aged obese women that had been on the rise as a part of efforts to activate the silver clothing industry. The subjects were in the age range of 60-79 and met some obesity requirements, including a Rohrer Index of 1.6 or higher, a BMI of 25 or higher, and a WHR of 0.85 or higher. Old-aged obese women showed increased thickness of the torso with age, which suggests that they revealed the characteristics of regardless of gender. In other words, they became bigger in the waist and abdomen, shorter in height, slimmer in the lower body, and thicker in the torso. There are three types of obesity: Type 1 is lower-body obesity with a higher degree of obesity in the abdomen than the upper body. Type 2 is abdominal obesity with a higher degree of obesity in the upper body than in the lower body. Type 3 is whole-body obesity with balanced obesity of the whole body. As for changes to the types of obesity according to age, those who are in their sixties usually fall into the categories of upper-body and whole-body obesity, and those who are in their seventies are much more concentrated in the categories of abdominal obesity and upper-body obesity with a decreased percentage of whole-body obesity. It is apparent that the percentage of abdominal and upper-body obesity rises with age due to fat accumulation in the abdomen.

Poria cocos is a well-known traditional Chinese traditional medicine (TCM) that grows around roots of pine trees in China, Korea, Japan, and North America. Poria cocos has been used in Asian countries to treat insomnia as either a single herb or part of an herbal formula. In a previous experiment, pachymic acid (PA), an active constituent of Poria cocos ethanol extract (PCE), increased pentobarbital-induced sleeping behaviors. The aim of this experiment was to evaluate whether or not PCE and PA modulate sleep architectures in rats as well as whether or not their effects are mediated through GABAA-ergic transmission. PCE and PA were orally administered to individual rats 7 days after surgical implantation of a transmitter, and sleep architectures were recorded by Telemetric Cortical encephalogram (EEG) upon oral administration of test drugs. PCE and PA increased total sleep time and non-rapid eye movement (NREM) sleep as well as reduced numbers of sleep/wake cycles recorded by EEG. Furthermore, PCE increased intracellular chloride levels, GAD65/67 protein levels, and α-, β-, and γ-subunits of GABAA receptors in primary cultured hypothalamic neuronal cells. These data suggest that PCE modulates sleep architectures via activation of GABAA-ergic systems. Further, as PA is an active component of PCE, they may have the same pharmacological effects.

In this study, several kinds of active carbons with high specific surface area and micro pore structure were prepared from the coconut shell charcoal using chemical activation method. The physical property of prepared active carbon was investigated by experimental variables such as activating chemical agents to char coal ratio, flow rate of inert gas and temperature. It was shown that chemical activation with KOH and NaOH was successfully able to make active carbons with high surface area of 1900~2500 m2/g and mean pore size of 1.85~2.32 nm. The coin cell using water-based binder in the electrolyte of LiPF6 dissolved in mixed organic solvents (EC:DMC:EMC=1:1:1 vol%) showed better capacity than that of oil-based binder. Also, it was found that the coin cell of water-based binder shows an improved cycling performance and coulombic efficiency.

Objective : The purpose of this study was to investigate the effects of Expiratory Muscle Strength Training (EMST) on the suprahyoid muscle activation and swallowing function of stroke patients.Methods : This study randomly assigned 21 stroke patients to an experimental group and a control group. Four-week EMST was performed at resistance of 70% of the maximum expiratory pressure with the experimental group and at resistance of 20% of that with the control group. Evaluation was conducted using surface Electromyographic (sEMG), Videofluoroscopic Dysphagia Scale (VDS), and Penetration-Aspiration Scale (PAS) based on Videofluoroscopic Swallowing Study (VFSS).Results : There was a statistically significant difference in the activation of the suprahyoid muscles using sEMG of the experimental group (p<.05) while there was no significant difference in that of the control group. Both group showed significant difference in the pharyngeal phase of VDS and PAS. Also in the comparison of variation in VDS and PAS before and after the intervention, there were statistically.Conclusion : Finding from this study confirmed that EMST applied 70% maximum expiratory resistance would be a remedial method which could help activate pharyngeal dysphagia patients’ suprahyoid muscles and improve swallowing function.

The activation of glial cells in the spinal cord has been contribute to the initiation and maintenance of pain facilitation induced by peripheral inflammation and nerve injury. The present study investigated effects of botulinum toxin type A (BoNT-A), injected subcutaneously or intracisternally, on the expression of microglia and astrocytes in rats. Complete Freund’s Adjuvant (CFA)-induced inflammation was employed as an orofacial chronic inflammatory pain model. A subcutaneous injection of 40 μL CFA into the vibrissa pad was performed under 3% isoflurane anesthesia in SD rats. Immunohistochemical analysis for changes in Iba1 (a microglia marker) and GFAP (an astrocyte marker), were performed 5 days after CFA injection. Subcutaneous injection of CFA produced increases in Iba1 and GFAP expression, in the ipsilateral superficial lamia I and II in the medullary dorsal horn of rats. Subcutaneous treatment with BoNT-A attenuated the up-regulation of Iba1 and GFAP expressions induced by CFA injection. Moreover, intracisternal injection of BoNT-A also attenuated the up-regulated Iba1 and GFAP expressions. These results suggest that the anti-nociceptive action of BoNT-A is mediated by modulation activation of glial cells, including microglia and astrocyte.

Lonicera japonica 에탄올 추출물의 처리에 의하여 LPS에 의해서 활성화된 RAW 264.7 세포에서 NO의 생성량과 TNF-α, IL-1β 및 IL-6와 같은 염증성 사이토카인의 분비를 억제하였고, MAPK family인 ERK, p38 및 JNK의 인산화와 Iκ-Bα의 분해를 억제하였다. LPS로 유도한 endotoxin shock 동물실험에서 Lonicera japonica 에탄올 추출물 20 mg/kg에서 LPS로 유도한 endotoxin shock에 대한 생존율을 3배 이상 증가시켰으며, 생존시간도 1.3~1.4배 증가시켰다.

고로슬래그는 유동성 장기강도 및 내구성이 좋고 수화열을 낮아 경화체를 제조함에 따른 적용성이 우수하지만, 몇 가지 문제점을 갖는다. 시공시간이 증가하고 회전속도가 늦고 초기강도가 낮다. 본 연구에서는 알칼리활성화를 이용한 경화체 제조에 있어 필요한 알칼리 수용액을 해수담수화 과정에서 발생하는 농축수의 전기분해를 통하여 공급하였으며. 알칼리 수용액을 이용하여 고로슬래그와 경화체를 제작하였다. 결과는 다음과 같이 요약할 수 있다 : 모르타르의 압축강도는 NaOH 2%이하일 때는 감소하고, 6% 이하까지는 증가한다. 그리고 NaOCl의 함량이 증가할수록 압축강도도 증가한다. 그러나 NaCl이 모르타르에 존재하면 초기강도보다 재령 28일차 강도는 감소하게 된다.

2001. 1. 28. 민영교도소 등의 설치ㆍ운영에 관한 법률(법률 제6206호)이 제정되었다. 그러나 법률만 제정되었을 뿐 올바른 민영교도소의 설치ㆍ운영은 기대에 미치지 못하고 있는 실정이다. 국내 유일의 민영교도소인 아가페 소망교도소의 경우에도 정부지원으로 운영되고 있어 재정적인 측면에서는 비효율적이다. 현시점에서 중요한 문제는 일정한 유형의 민영교도소를 병행 설치ㆍ운영하여 국민의 혈세를 줄이고 수용자의 빠른 재사회화를 유도하는데 있다. 엄격한 규율과 적정임금을 도입하여 재범률을 줄이면서 직업창출에도 선도적 역할을 할 수 있도록 혁신할 필요가 있는 부분이다. 이에 민영교도소 관련 법률을 검토하고 외국의 사례를 참조할 필요가 있다. 민영교도소 운영과 관련하여 새로운 경영기법을 도입하고 설립단계에서부터 비용을 최소화할 수 있는 방안을 강구하여야 할 것이다. 감독관 형태의 교정직렬 공무원에 대해서는 대우를 달리하고 그 동안 시설운영의 실질적 기술을 전수할 수 있는 기회를 부여하여야 할 것이다. 특히 예산의 배분과 집행방법 등에 대해서 회계처리 기준을 지도할 필요가 있다. 이러한 과정에서는 민영교도소의 주체를 분명히 하는 대신 이를 지도ㆍ감독하는 방법으로 교정행정에 혁신을 불러오는 등 커다란 발전을 기대해 본다.

본 연구에서는 총백 특유의 향과 항산화 기능 등으로 알 려진 alliin과 allicin의 추출 최적 조건을 정립하기 위해 추 출용매, 추출온도, 추출시간 등을 달리하여 alliin과 allicin 의 함량을 측정하였다. 또한, 총백의 alliinase 활성화 조건 에 따른 allicin의 함량의 변화를 알아보기 위해 생총백을 물과의 혼합비율, 수침온도, 진탕시간을 달리하여 처리하여 allicin 함량을 비교하였다. 결과적으로, alliin은 총백 추출 조건 중 추출용매로 물을 사용하여 40oC에서 2시간 추출 하였을 때, 86.477 mg/g으로 최대함량을 보였으며, allicin의 경우, 70% ethanol, 70oC, 2시간 추출조건에서 1.371 mg/g 으로 최대함량을 나타냈다. 본 실험에서는 총백의 추출 조 건을 alliin의 함량이 크게 감소하지 않고, allicin의 함량이 최대로 추출될 수 있도록 70% ethanol, 70oC, 2시간으로 추출조건을 설정하였다. Alliinase 활성화 처리 조건에서는 생총백과 물을 1:1 혼합하여 40oC에서 30분간 진탕하였을 때, 0.111 mg/g로써 최대의 allicin 함량을 보였다. 본 실험 결과, 다양한 추출조건에서 alliin과 allicin의 함량이 높은 총백추출물을 제조함으로써 원가경쟁력이 높은 총백추출물 기반 기능성 소재 또는 식품을 개발하는데 기여할 수 있을 것으로 사료된다. 또한, alliinase 활성화를 통한 allicin의 최적 추출방법을 확립함으로써, 총백 이외의 마늘, 양파, 대파 등 allium 속 식물을 이용한 allicin 개발을 타겟으로 하는 연구자들뿐만 아니라 전반적인 기능성 식품 산업에 있어서 소재 개발을 위한 기초자료가 될 수 있을 것이다.

In vitro 실험을 통한 가시오가피 물 추출물 첨가가 마우스 의 면역세포 증식에 미치는 영향에 대한 연구 결과, 음의 대 조군에 비해 가시오가피 물 추출물을 첨가한 모든 농도에서 비장세포 증식능이 증가하였으며, 특히 고농도인 500~1,000 μg/ mL 농도에서 유의적으로 증가하였다. 반면, 복강 대식세 포로부터 유도된 사이토카인 생성의 경우, IL-2, IFN-γ, TNF- α 사이토카인 생성량을 측정한 결과, TNF-α 사이토카인은 가시오가피 물 추출물 50 μg/mL 농도와 250~1,000 μg/mL 농 도에서 대조군보다 유의적으로 높은 분비량을 보인 반면, IFN-γ에서는 변화를 보이지 않았다. IL-2의 경우, 100~500 μg/ mL에서 유의적으로 증가하는 경향을 보여주었다. 이상의 결 과에 의하면 가시오가피 물 추출물은 마우스 비장 세포를 증 식시키고, 사이토카인 분비량에도 영향을 줄 것으로 보이며, 면역 기관의 주요 기능을 증진시킬 가능성이 있을 것으로 사료된다. 따라서 가시오가피 물 추출물이 면역 증진 기능성식 품 개발의 소재로 활용될 가능성이 있을 것으로 기대된다

Activated carbon fibers(ACFs) were prepared in this research from a polyacrylonitrile(PAN) precursor with the KOH(1~4 M) pretreatment and following activation at 800oC in a lab-scale. The sample ACFs were characterized according to their textural properties, and evaluated for CO2 adsorption capacity. The surface area and pore volume of ACFs increased according to the pretreatment with KOH; for example, 4M-KOH aqueous solution resulted in 1552.5 m2/g specific surface area and 0.605 cc/g pore volume. It also showed high CO2 adsorption amount(3.11 mmol/g) which showed a proportional increase with reaction pressure.

The purpose of this study was to compare the change in electromyography (EMG) activity in the gluteus maximus (G-max) and the gluteus medius (G-med) in subjects with and without chronic ankle instability (CAI) during three functional postures. Twenty four females were recruited for this study. Subjects were assigned into two groups: with CAI (n1=12) and without CAI (n2=12). The assessment postures were rotational squat, one leg stand above a gradient and crossed leg-sway. Electromyographic activities of the G-max and the G-med were recorded using surface EMG and was normalized using the maximal voluntary isometric contraction elicited using a manual muscle testing. Independent t-test was used to determine the statistical differences between two groups during the three functional postures. The comparisons of the three posture between two groups were performed using a one-way repeated analysis of variance. A Bonferroni adjustment used for post hoc analysis. The activation of EMG on G-max performing the one leg stand above a gradient and crossed leg-sway in subjects with CAI is significantly higher than normal group (p<.05). The activation of EMG on the G-max during the rotational squat was significantly increased, compared to those of the one leg stand above a gradient and crossed leg-sway (p<.05). The activation of EMG on G-med performing three exercise at CAI is significantly higher than normal group (p<.05). The activation of EMG on the G-med during the crossed leg-sway was significantly increased, compared to the rotational squat (p<.05). This study provides valuable information for clinician who research CAI.

Allergic diseases have increased rapidly over the past decades, affecting an estimated 20~30% of the population in developed countries. In this study, we investigated whether or not a typical costal sand dune plant Carex pumila (CPE) suppresses the activation of mast cells and IgE-mediated allergic response in vitro and in vivo. As the results, the extract of Carex pumila inhibited antigen-stimulated degranulation in RBL-2H3 cells and Bone marrow-derived mast cells (BMMCs), and IgE-mediated passive cutaneous anaphylaxis (PCA) in mice. CPE also suppressed the production of pro-inflammatory cytokines, TNF-α and IL-4, in antigen-stimulated mast cells. As its mechanism of action, CPE inhibited the activation of Syk in FcεRI-mediated signalling pathway, and that of LAT, a downstream adaptor molecule of Syk, in a dose-dependent manner. CPE also suppressed the activation of mitogenactivated protein (MAP) kinases, p38, ERK1/2, JNK, and Akt. Altogether, CPE inhibited mast cell activation and IgEmediated allergic response by antigen through suppressing the activation of Syk. These results suggest that CPE may be useful for the treatment of allergic diseases.