The printing of nanomaterials onto certain substrates is one of the key technologies behind high-speed interconnection and high-performance electronic devices. For the printing of next-generation electronic devices, a printing process which can be applied to a flexible substrate is needed. A printing process on a flexible substrate requires a lowtemperature, non-vacuum process due to the physical properties of the substrate. In this study, we obtained well-ordered Ag nanowires using modified gravure printing techniques. Ag nanowires are synthesized by a silver nitrate (AgNO3) reduction process in an ethylene glycol solution. Ag nanowires were well aligned by hydrodynamic force on a micro-engraved Si substrate. With the three-dimensional structure of polydimethylsiloxane (PDMS), which has an inverse morphology relative to the micro-engraved Si substrate, the sub-micron alignment of Ag nanowires is possible. This technique can solve the performance problems associated with conventional organic materials. Also, given that this technique enables large-area printing, it has great applicability not only as a next-generation printing technology but also in a range of other fields.

The present study investigated the urinary tract toxicity of melamine alone or in combination with cyanuric acid in rats. Male rats were orally administered melamine alone (800 mg/kg) or melamine plus cyanuric acid (50 mg/kg each) for 3 consecutive days. Although melamine treatment did not show any significant difference in body weight, kid- ney or urinary bladder weight, serum blood urea nitrogen (BUN) or creatinine levels, it caused a decrease in urinary pH and mild histopathological alterations in the kidney and urinary bladder. In contrast, co-administration of melamine and cyanuric acid induced a decrease in body weight, an increase in kidneys and urinary bladder weights, and an elevation in serum BUN and creatinine levels, which were not observed in animals treated with melamine alone. His- topathological examination showed that the incidence and severity of histopathological lesions in the kidney and uri- nary bladder were much higher than those in the melamine group. Urinalysis revealed an increase in urine occult blood, leukocytes and protein and a decrease in urinary pH. These results indicate that concomitant administration of cyanuric acid synergistically potentiated the urinary tract toxicity induced by melamine in rats. In this study, we first demon- strated the synergistic toxic effects of melamine in combina- tion with cyanuric acid on urinary bladder and urinalysis in rats.

한자교육과 독해의 결합은 전통적인 중국의 어문 한자교육에서 중시받고 귀감 으로 삼아야 할 귀중한 경험 중 하나이다. 이 경험은 한자의 특성과 규칙과 부합 할 뿐 아니라, 학생들로 하여금 한자의 형음의를 통일하여 연결하여 학습하게 하 는 훌륭한 기초를 마련해 줌으로서 한자교육의 범위를 넓혀 준다. 또 한 측면에서 한자교육의 효과는 언어를 운용하는 범주에까지 나아가 학생들로 하여금 훌륭한 언어 감각을 배양하게 하여 언어 운용의 훌륭한 기초를 쌓도록 하여준다.

PURPOSES : This study is to suggest suitable lighting facility installation plans by finding out driver's preference for combination of lighting facility installation among landscape factors that affect driver visibility in tunnels. METHODS : SD method is used to extract emotional factors that affect drivers' preference, Components of tunnel lighting facility installation are evaluated through conjoint analysis and it suggested relative importance of attributes and utility values. RESULTS : In the aspects of satisfaction levels of components of tunnel lighting facility installation, Tunnel side, two lows, and solid line arrangement type has the highest level of satisfaction. Extract emotional factors that affect drivers' preference are "safety", "openness" and "amenity." In addition, the result of analyzing relative importance of attributes of tunnel lighting facility shows that numbers of lighting array has the highest importance and lighting facility arrangement has the lowest importance. Result of analyzing partial utility shows that the 2 low type among number of lows, the solid line arrangement type between arrangement types, placing in the middle part among lighting facility arrangement were highly preferred. CONCLUSIONS : In the case of lighting numbers, utility values of the first line and the second line showed us a big difference. Increasing the number arrays in the future reformation of lighting facility installation combination will be effective in enhancing the utility of the driver.

One of representative Korean fisheries, jigging and angling has 5,700 vessels for squid and hairtail. Hairtail angling is the most typical fishery in Jeju and has an enormous impact on regional economy. However, the price hike in oil and labor costs triggered the necessity of developing a high efficient and energy saving fish luring lamp in recent times. For that reason, this study aimed to analyze the fishing performance of the aircooled LED lamp targeting hairtail angling fishery. The experiment was conducted from September through October in 2009-2011 for a 9.77 ton of fishing vessel setting up 100 lamps. The fishing performance was tested compared with 6 vessels using metal halide lamps in the same waters. As the LED lamp's performance goes up, different lamps were used in 2008 for 80W, 2009 for 120W and 2011 for 180W respectively. The catch and CPUE of the experimental vessel have gradually increased respectively taking the 4th and 6th place in 2009, the 4th and 2nd place in 2010, the 1st and 1st place in 2011 among the 7 vessels. In summary, the LED fishing lamp showed higher fishing performance than comparison groups. It saved 33% of oil consumption and cut down on operating expenses and greenhouse gases emission.

A study was investigated the effects of the probiotic mixture (PM) contained Lactobacillus plantarum (L. plantarum) SY-99 2.4×109 CFU/kg and Bacillus subtilis (B. subtilis) SJ-61 2.2×109 CFU/kg on growth performance and fecal microflora counts of broiler chickens. Referred to the previous studies, a total of 160 one-day-old male broiler chicken (Ross 308) were randomly assigned to four experimental groups, which were a basal diet alone (control) and supplemented with PM 0.1 g/kg feed (T1), PM 0.2 g/kg feed (T2), and PM 0.4 g/kg feed (T3). After 28 days of administration, the average daily feed intake of T1 and T3 was significantly different compared to that of control (p<0.05). In addition, the feed conversion ratio of T2 and T3 was significantly improved compared to that of control (p<0.05). On the 28th day after administration, all treatment groups were significantly increased fecal lactic acid bacteria (LAB) counts and decreased fecal Enterobacteriaceae (ENT) counts compared to T1 (p<0.05). The results of this study indicated that the combination of L. plantarum and B. subtilis strains in the range of 0.2-0.4 g/kg feed could be used for the improvement of growth performance and fecal microflora in broiler chickens.

This study was designed to determine whether low-density lipoproteins (LDL) from egg yolk and taurine, hypotaurine and trehalose as antioxidant in extender improve the freezability and fertility of Korean Jeju Black Bull semen. The semen was cryopreserved with tris egg yolk extenders containing 7% glycerol and treated 4% LDL, 20 mM taurine, hypotaurine and trehalose. Frozen-thawed sperm were evaluated motility, viability, membrane, and acrosome integrity and sperm penetration ability. The results were compared to semen cryopreserved in tris egg yolk extender only as control. Frozen-thawed semen evaluation cleary indicated that the addition of LDL and LDL-antioxidants (taurine, hypotaurine and trehalose) combination were significantly improved (p<0.05) the viability (%; with staining test using eosin-Y) compared to control spermatozoa. Also, in membrane integrity (%; with supravital hypo-osmotic swelling test), not only LDL-antioxiants combination but also LDL were significantly increased (p<0.05) the swelled sperm using HOST compared to control. Sperm acrosome integrity state was classified by CTC (chlortetracycline) staining test. F pattern was significantly increased in LDL-antioxidant combination than control (p<0.05) and B pattern was not significantly differences among all treatments and control. However, AR pattern was significantly decreased in LDL-antioxidants combination than control (p<0.05). Pronucleus formation and sperm penetration index (SFI) were significantly increased in LDL and LDL-antioxidants combination than control (p<0.05). Especially, LDL-taurine significantly improved pronucleus fomation and SFI than LDL (p<0.05). It was concluded that LDL and LDL-antioxidants in extender improved the freezability and fertility of Korean Jeju Black bull spermatozoa.

Nanocrystalline powder could be synthesized by solid-state reaction using the mixture which was prepared by a high energy milling process in a bead mill for and nanocrystalline powders mixture. Effect of the milling time on the powder characteristic of the synthesized powder was investigated. Nanocrystalline with a particle size of 50 nm was obtained at . High tetragonal powder with a tetragonality(=c/a) of 1.009 and a specific surface area of was acquired after heat-treatment at for 2 h. High energy ball milling was effective in decreasing the reaction temperature and increasing the tetragonality.

Our previous study demonstrated that fermented four-herb combination (Ulgum, Yagmomil, Maesil and Bokbunja) with probiotics (Saccharomyces cerevisiae, Lactobacillus acidophilus, Bacillus subtilis) (hence, this additives was designated PFH) have immune enhancing and antibacterial effects in broiler chickens. The aims of the present study were to investigate the effects of PFH on growth performance and meat quality of broiler chickens. Twenty-day-old Ross broiler chickens were fed with or without PFH for 2 weeks. Body weight gain of the 2% PFH-fed group was significantly increased compared with those of the control group (*P<0.05). Moreover, body weight gain of the 1% PFH-fed group was also showed a increased tendency compared with the control group, although the difference was not significant (P=0.06). However, no significant difference in feed intake was observed among the groups. Feed conversion ratio of the 2% PFH-fed group was significantly decreased compared with those of the control group (*P <0.05). In addition, feed conversion ratio of the 1% PFH-fed group was also showed a slightly decreased tendency compared with the control group, although the difference was not significant (P=0.07). However, no significant differences in the proximate composition (moisture, crude fat, crude protein and crude ash) and the physico-chemical index (cooking loss, shearing force, water holding capacity and pH) were found among the groups. In addition, succulence, tending and flavor in meat of all 3 groups were also not different. Taken together, these findings suggest the possibility that PFH could be used as the alternative of antibiotic growth promoters by improving the performance of broiler chickens.

Risk ranking must be determined for various hazards/food combinations to conduct microbial risk management effectively. Risk Ranger is a simple, easy-to-use calculation tool developed in Microsoft Excel and designed to rank the risk (low, medium, and high) for semi-quantitative microbial risk assessment. The user is required to answer 11 questions in Risk Ranger related to 1) severity of the hazard, 2) likelihood of a disease-causing dose of the hazard being present in the meal, and 3) the probability of exposure to the hazard in a defined time. This study determined the risk ranking for twenty three combinations of foodborne pathogens/potentially hazardous foods (PHFs) using a Risk Ranger. In this study, pathogenic E. coli in fresh cut produce salad was scored as 79, which was the highest rank among the 23 combinations of the foodborne pathogens and PHFs. On the other hand, zero risk was obtained with V. parahaemolyticus in sushi, Salmonella in meat products and E. coli O157:H7 in hamburger patties. Although Risk Ranger is very simple method to rate the risk of foodborne pathogens and PHFs combination, the accuracy of result was mainly affected by the availability and accuracy of data in the literature. According to the result of literature review, the data are needed for contamination rate of raw materials, consumption amount/frequency of PHFs, and the effect of processing on pathogen. Risk ranking must be continuously revalidated with new data.

본 연구는 결혼 예식장 종류에 따른 서비스스케이프 배색 이미지를 호텔 예식 연회, 일반 예식장, 종교 결혼식장 간에 비교하여 분석하고자 하였다. 서울 및 경기 지역 20~39세 400명을 대상으로 직접 방문 및 우편조사를 실시하였고 315부를 분석에 사용하였다. 통계 분석은 SPSS/WIN 17.0을 사용하였고, 신뢰도 분석, 요인분석, t-test, 분산 분석 등을 실시하였다. 요인 분석 결과 결혼식장 배색 이미지는 경쾌함, 고상함, 은은함의 3개 요인으로 분석되었다. 크론바하 알파값이 조사 도구의 신뢰도 분석을 위해 사용되었으며, 0.7 이상을 나타내어 적합하게 나타났다. 결혼식장 배색 이미지 분석 결과, '깨끗한'이 3.60으로 가장 높게 나타났으며, '온화한' 3.50, '은은한' 3.38 순으로 나타났다. 결혼식장 배색 이미지에 대한 결혼식장 유형별 차이를 분석한 결과 통계적으로 유의한 차이를 나타냈으며, 배색 이미지 중 '경쾌함' 요인은 일반 예식장이 3.00, '고상함' 요인은 호텔 결혼식장 3.64, '은은함' 요인은 호텔 결혼식장에서 3.60으로 가장 높게 나타났다. 결혼식장 배색 이미지에 대한 인구통계학적 차이 분석 결과, 성별, 결혼 유무, 한달 총수입에 따라 통계적으로 유의한 차이가 나타난 반면, 연령, 학력, 직업에 따른 차이는 나타나지 않았다. 본 연구 결과는 결혼식장 색채 마케팅 연구의 기초 자료로 활용될 수 있을 것으로 기대된다.

Photodynamic therapy(PDT) is recently developed as an effective treatment for malignant disease. Carboplatin, a less nephrotoxic analog of cisplatin, has been widely used for the treatment of multiple malignancies. In this study, we investigated the cytotoxic and apoptotic effect of combined modality of photofrin mediated PDT with cisplatin and carboplatin on KB cell human oral cancer cell line in vitro. The a ttached KB cells were incu bated with c isplatin(0.04mg/ml) and carboplatin(0.02mg/ml) for 24h at 37℃ and followed by photosensitization with photofrin for 6h and laser irradiation with 630nm LED at an intensity of 2.0 J/cm2 for activating photofrin for 15min. Then MTT assay and SYTO 16 green & Propidium iodide (PI) double staining were used respectively to measure the cytotoxicity and nuclear morphology at 24h after PDT. This study demonstrates that the combined modality with carbopaltin resulted in enhanced apoptotic cell death as well as cytotoxic e ffect on KB c ells in vitro, which s uggests the feasibility of combined modality and the possibility o f reducing the effective dosage of photofrin and carboplatin and lowering the side effects on normal cells

최근 많은 기업 또는 영리단체들은 급변하는 주변환경에 대응하기 위하여 다양한 혁신 방법들을 도입하여 운용하고 있는데, 하나만의 혁신기법들만을 적용한다는 것은 기업 또는 단체들에게 보다 긍정적인 결과를 얻어내기에 부족함이 있다. 본 연구에서는 혁신방법 중에서TRIZ와 6시그마의 혼합방안을 제시하기 위해서 다음의 세 가지 내용을 중점적으로 연구하였다. 첫째, TRIZ와 6시그마의 이론과 운영시스템을 설명하였다. 둘째, TRIZ와 6시그마에 대한 공통점, 차이점, 품질경영측면에서의 비교를 통하여 TRIZ와 6시그마와의 관계를 정립하고 올바른 이해를 제시하였다. 셋째, 6시그마의 진행 단계에서 TRIZ기법이 도움을 줄 수 있는 부분을 분석하고 6시그마와 TRIZ를 혼합한 새로운 모형과 예를 제시하였다.

Chronic inflammatory diseases such as Crohn′s disease and ulcerative colitis are associated with increased risk of colon adenocarcinoma. Apoptic induction of colon cancer cells by cytokines and death receptors is an important anti-cancer therapy. We observed that co-administration of TNFα and IFNγ in human colon cancer cell line, HCT116, resulted in cell death and expression of IL-32. Cleavage forms of caspase-3, caspase-9, and PARP were increased in TNFα / IFNγ-treated HCT116. mRNA expression of death receptors, including TNFR1 and Fas were not changed and NO generation was not induced by combination of TNFα and IFNγ. However, mRNA expression of IL-32α, β, and γ was increased in TNFα / IFNγ-treated HCT116. To determine the effect of IL-32 in HCT116 cell apoptosis by TNFα / IFNγ stimulation, IL-32 siRNA-transfected HCT116 cells were cultured with TNFα / IFNγ and cell proliferation was measured. IL-32 siRNA induced slight recovery of cell viability of TNFα / IFNγ-stimulated HCT116. These results suggest that IL-32 is not directly related to apoptosis of HCT116 by TNFα / IFNγ stimulation. However, IL-32 expression by TNFα or TNFα / IFNγ in a colon cancer cell line is very interesting because of the unknown effect of IL-32 in colon cancer. Our study will contribute to development of studies for IL-32 function in human colon cancer and anti-cancer therapies using cytokines.

본 연구는 톤 인 톤 배색과 톤 온 톤 배색을 활용한 배색의 감성 효과에 관한 것이다. 톤 인 톤 배색 과 톤 온 톤 배색에 근거하여 제작한 24개 배색에 대하여 Osgood의 SD법(Semantic Differential Method)을 이용하여 10명 대학생에게 배색에 대한 인상 평가를 받았으며 자료 분석은 엑셀 통계 프로그램 2004를 사용하여 요인분석을 하였다. 연구결과, 톤 인 톤 배색에 근거한 배색과 톤 온 톤 배색에 근거한 배색의 인상이 매우 다르게 평가되는 것을 확인했다. 따라서 색채조화의 형식으로 제안되는 배색 기법이 배색의 감성 효과에 영향을 미칠 가능성을 확인하였다. 그리고 '좋다-싫다', '어린이답다-어른답다', '강하다-약하다', '따뜻하다-차갑다' 4개 이미지 차원이 도출되었으며 이러한 이미지에는 색상과 색조가 영향을 주는 요소로 작용한다는 것을 확인하였다. 제품의 사진배색과 거의 동일한 색종이 배색의 인상을 비교한 것으로 색표를 이용한 배색과 그 배색에 근거한 제품의 배색 인상에는 거의 차이가 없다는 것을 확인하였다. 그러나 제품이 가진 고유 특성이나 형태, 재질 등에 의해 인상이 크게 달라지는 것도 확인하였다. 이러한 연구 결과는 배색 이미지나 색채 디자인의 기초 자료로 활용 될 것이다.

Electroantennogram techniques (EAGs) were employed to record olfactory responses in the antennae of the adult female stable fly, Stomoxys calcitrans (Diptera: Muscidae), to Zanthoxylum piperitum pericarp steam distillate (ZP-SD), Z. armatum seed oil (ZA-SO) and their 29 volatile constituents alone as well as binary mixture of the ZP-SD and ZA-SO with 1-octen-3-ol. The electrophysiological responses of the test materials were compared with those of DEET and 1-octen-3-ol. At concentration of 10-1 (v/v) in mineral oil, ZP-SD, ZA-SO, and all volatiles elicited EAG responses in the fly antennae except for DEET, which is extremely low volatile. ZP-SD, ZA-SO, and some of the test volatiles elicited EAG responses rather lower than 1-octen-3-ol, which showed vapor phase repellency and toxicity to the fly in our previous behavioral research. This suggests that the stable fly possesses olfactory receptor neurons responding to given repellent compounds per se. In binary mixture with 1-octen-3-ol at concentration of 10-1, ZP-SD and ZA-SO elicited 16±0.55 and 18±0.63 mV while ZP-SD, ZA-SO, and 1-octen-3-ol alone elicited responses of 14±0.45, 15.8±0.37 and 16.2±0.58 mV, respectively. Among the volatile compounds, terpinen- 4-ol, β-myrcene, α-phellanderene, citronellal, and limonene oxide elicited 80 – 96% relative EAG amplitude compared to 1-octen-3-ol as a reference (100%). Based on structure-activity relationships, constituents having aldehyde moiety elicited bigger EAG responses than those of alcohol or ether one. The perception in the fly antenna to plant volatile compounds exhibited complicated patterns of olfactory responses. Current and future directions of this study on sensory processing mechanisms underlying repellent behaviors will be discussed.