This study investigates the effects of experiential marketing by categorizing fashion pop-up store experiences according to the strategic experiential modules (SEMs): sensory, emotional, cognitive, behavioral, and relational. It analyzes how these experiential factors influence shopping flow, impulse buying, and word-of-mouth intentions. A survey was conducted with 400 participants, equally distributed by gender and age group (20 and 30-year-old). Valid responses from 320 participants were analyzed using factor analysis, reliability testing, correlation analysis, and regression analysis in SPSS. Findings revealed four key elements of experiential marketing: sensory/emotional, relational, cognitive, and behavioral. Sensory/emotional, relational, and cognitive factors positively affected shopping flow, which enhanced impulse buying and word-of-mouth intentions. However, behavioral factors did not have a significant effect. These results underscore the impact of experiential marketing on pop-up store customer behavior and highlight the understudied area of word-of-mouth marketing. The study specifically targeted consumers most likely to visit pop-up stores, ensuring practical significance by providing data to develop strategies for increasing experiential marketing efficiency. Additionally, the results identify the critical elements of experiential marketing in pop-up stores and examine how they interact with shopping flow and impulse buying. This research contributes valuable insights into optimizing consumer engagement in pop-up retail environments, emphasizing the importance of sensory and relational experiences in driving consumer behavior and addressing gaps in existing marketing literature.

Lumpy Skin Disease (LSD) and Foot-and-Mouth Disease (FMD) cause substantial economic losses on the livestock industry. Therefore, vaccinations have been implemented as the control strategy in endemic countries. However, the potential adverse effects of administering vaccines for both diseases simultaneously have not been thoroughly evaluated. The aim of this study was to assess the impact of vaccinating dairy cows with either or both LSD and FMD vaccines on milk production and physiological parameters such as milk temperature, rumination time and body weight. The experimental groups were divided into four according to the injection materials: 1) saline, 2) LSD vaccine, 3) FMD vaccine, and 4) both vaccines. The impact of vaccination on milk yield and physiological parameters was evaluated daily until 12 days post-vaccination, and milk components were analyzed twice, once per week. Among the experimental groups as well as each vaccine group, no statistically significant differences (p < 0.05) were observed at milk yield, milk components, or milk temperature. This suggests that simultaneous vaccination of LSD and FMD can be administered without adverse effects.

본 연구는 2023년 방영된 일본 애니메이션 '최애의 아이'의 구전 마케 팅 전략을 마케팅 믹스(4P) 관점에서 분석했다. 연구 방법으로는 내용분 석 방법을 활용하였으며 연구 결과는 다음과 같다. 제품 측면에서는 아 카사카 아카와 요코야리 멩고의 시너지적 협업을 통한 높은 완성도, 판 타지와 리얼리티의 장르적 융합이 돋보였다. 가격 측면에서는 OTT 서비 스를 통한 접근성 확대, 한정판 굿즈를 통한 프리미엄 전략, 무료 콘텐츠 를 활용한 초기 팬베이스 구축이라는 균형적 접근이 효과적이었다. 유통 측면에서는 애니플러스와 크런치롤 같은 글로벌 OTT 플랫폼 활용, 다국 어 자막과 현지화된 마케팅 전략, 팬 커뮤니티를 통한 자발적 확산이 주 목할 만했다. 촉진 측면에서는 틱톡 챌린지 캠페인, J-POP 최단기간 1억 뷰를 달성한 오프닝 곡의 전략적 활용, K-pop 아이돌과의 크로스오버 전략이 글로벌 인지도 확대에 결정적 역할을 했다. 연구 결과는 현대 콘 텐츠 마케팅에서 마케팅 요소들의 유기적 결합, 팬덤의 자발적 참여 유 도, 크로스오버 마케팅의 중요성을 시사하며, 본 연구는 소셜 미디어 시 대의 콘텐츠 마케팅 전략 수립에 실천적 함의를 제공한다.

Because intact FMDV particles (146S) are often unstable in vitro, stabilizing foot-and-mouth disease virus (FMDV) antigens remains a key challenge in studying viral charateristics. Therefore, finding optimal condition to stabilize the FMDV is essential. In this study, we investigated formulations and potentials of several stabilizers such as appropriate buffer, excipients, and storage conditions to enhance the stability of 146S. Inactivated FMDV O-Jincheon (O-JC) was dissolved in various buffer formulations, and stored at 4℃ for two months to evaluate quantity of 146S at every 2-week interval. Among phosphate buffered saline (PBS), Tris buffered saline (TBS), HEPES buffered saline (HBS), and MOPS buffered saline (MBS), PBS showed more effective 146S stabilization that showed 1.3-1.6 fold higher 146S fraction than TBS, HBS, and MBS after storage for 2 weeks. However, constant dissociations of 146S were observed in all formulations at 8 weeks. Compared with other FMDVs, A22 Iraq and SAT-1, in PBS, O-JC proved to be the least stable in PBS. A variety of excipients including carbohydrate, sugar alcohol, cryo-protectant were tested for the capability in protecting O-JC from dissociation. By adding 4-8% sucrose, more than 60% of 146S fractions were maintained at 8 weeks, those were at least 1.8 fold higher than the PBS-only control. Addition of 1% β-cyclodextrin showed synergistic enhancement in O-JC stability. As the results of this study, it could be suggested that the PBS-based buffer together with 4-8% sucrose + 2% sorbitol or 2% sucrose + 2% sorbitol + 1% β-cyclodextrin could help the better stability of the O-JC in vaccine preparation.

Burning mouth syndrome is a rare disorder of a complex nature that significantly impairs the life quality of those affected. Its clinical features are characterized by oral burning sensation as well as xerostomia, dysgeusia, and halitosis. While various etiological factors have been proposed over the last few decades, recent studies have focused on understanding its pathophysiology as a neuropathic disorder that involves both peripheral and central neuropathy. In addition, other explanations of BMS pathology have also been proposed, including hormonal disturbances during and after menopause, immunological challenges, and psychological distress. Despite these research efforts, the etiology of BMS remains elusive, awaiting further investigations. The scope of this review includes the current understanding of BMS pathology and animal models developed for deciphering molecular mechanisms underlying the development and progression of BMS. The overview of recent research efforts and our knowledge of BMS pathology will provide an opportunity to evaluate the status of our understanding of BMS and its future perspective in improving the life quality of those affected by this rather intractable disorder.

본 연구는 제주도 모슬포 해역에서 채집된 대형 포식성 복족류인 붉은입두꺼비고둥(Tutufa bufo) 두 개체를 대상 으로 테트로도톡신(TTX) 존재 여부를 조사하였다. 일본에 서 채집된 붉은입두꺼비고둥의 내장에서 TTX가 검출된 사례가 보고된 바 있으며, 최근 제주도 남부 해역에서 해 당 종이 혼획되고 있으나, 한국 해역에 분포하는 붉은입 두꺼비고둥의 TTX 축적에 대한 정보는 부족하다. 이에 본 연구에서는 경쟁적 효소면역분석법(cELISA) 을 사용하여 붉은입두꺼비고둥의 주요 연조직(전타액선, 구강부, 소화 선, 생식소, 아가미, 신장, 근육, 후타액선)을 분석하였다. 분석 결과, 모든 조직에서 TTX 농도는 검출 한계 미만으 로 나타났다. 그러나 TTX 축적에는 개체 간, 지역적, 계 절적 변동 가능성이 존재할 수 있으므로, 한국 해역에서 붉은입두꺼비고둥의 TTX 축적 위험을 정확하게 평가하기 위해서는 추가적인 시료 확보와 계절별 연구가 요구된다.

목적 : 일개 대학 안경광학과 대학생들의 지각된 스트레스, 주관적 건강상태, 안구건조 및 구강건조 증상의 관련 성을 알아보고자 한다. 방법 : 일개 대학 안경광학과 대학생 150명을 대상으로 일반적 특성 8문항, 스트레스 자각적도 10문항, 안구건 조 증상 8문항, 구강건조 증상 6문항을 온라인으로 설문 조사하였다. 통계분석은 독립표본 t-검정과 ANOVA 분 석, pearson의 상관분석, 회귀분석을 실시하였다. 결과 : 여학생이 남학생보다 지각된 스트레스와 안구건조 증상이 더 높았으며, 스마트폰 사용 시간이 7시간 이 상일 때 안구건조 증상이 유의하게 증가하는 것으로 나타났다. 또한, 음주자가 비음주자보다 낮은 스트레스를 지각 했으며, 안구건조와 구강건조 증상은 지각된 스트레스와 정적 상관관계를 보였다. 주관적 건강상태는 스트레스와 부적 상관관계를 나타냈으며, 특히 주관적 구강건강 상태가 나쁜 그룹은 스트레스 수준이 더 높았다. 결론 : 본 연구 결과는 지각된 스트레스가 안구건조 및 구강건조 증상과 관련이 있음을 시사하며, 학생들의 스 트레스 관리 및 건강상태 모니터링의 필요성을 강조한다. 추후 연구에서는 다양한 연령대와 스트레스 요인을 포함 한 연구가 필요할 것이다.

This study investigates consumer experiences and word-of-mouth (WOM) intentions in luxury brand pop-up stores, including standalone and department store setups. Grounded in experience economy theory, this study examines the experiential elements based on the types of pop-up stores and the relationships among consumer experience, pop-up store image, and WOM intentions for each type. Data were collected from 300 visitors to luxury brand pop-up stores between January and July 2023 and analyzed using Smart PLS 4.0. The findings reveal several key insights. First, standalone pop-up stores offer educational and escapist experiences, while pop-ups within department stores have a single identified factor of consumer experience. Second, regardless of the store type, luxury pop-up store experiences significantly influence pop-up image perceptions. Third, luxury pop-up store image drives WOM intentions for both standalone and department store pop-ups. Notably, the unique image significantly impacts solely department store pop-ups and does not influence standalone pop-ups. Moreover, image perceptions in both pop-up store types do not significantly affect brand WOM intentions. Finally, WOM intentions for pop-up stores significantly influence WOM intentions for brands. This study contributes to the theoretical understanding of consumer experiences in luxury pop-up stores, providing practical insights for stakeholders in the luxury brand industry to enhance pop-up store image perceptions and WOM intentions.

Hand, foot, and mouth disease (HFMD) is a highly contagious disease with no specific treatment. Since it is common in immunocompromised children under the age of 5, there is a need to develop a safe vaccine. Virus-like particles (VLPs) are similar structures to viruses with the lack of genetic material which makes them impossible to replicate and infect, and therefore have a high level of biological safety and are considered to have high value as vaccines. In this study, the insect virus expression system that is widely used for vaccine and drug production due to its high post-translational modification efficiency, was used to produce VLPs for Coxsackievirus type A6 and A10, which are recently reported to be the main causes of HFMD. For this purpose, the selection of promoters that can control the timing and intensity of expression of 3CD protein, which is essential for VLPs assembly but has been reported to be cytotoxic, was conducted to construct an optimal expression form for HFMD-VLP.

The limitation of markers for chronic oral diseases such as oral lichen planus (OLP) and burning mouth syndrome (BMS) is a diagnostic challenge for clinicians. The pathogenesis of OLP and BMS is not yet fully understood. Therefore, diagnoses are mainly based on the observation of clinical features and history, rather than established markers. C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are used to determine the state of inflammation; however, these markers have some limitations. Recently, a new inflammatory marker, pentraxin-3 (PTX3), has been identified in other systemic inflammatory diseases. PTX3 is a member of the pentraxin family and is classified as a long pentraxin. PTX3 is found in various human tissues, whereas the classical short pentraxin, CRP, is secreted only in the liver. PTX3 is a marker of autoimmune diseases and periodontitis. However, there are no studies on PTX3 in OLP and BMS; therefore, we sought to determine if PTX3 can be a diagnostic marker for OLP and BMS. PTX3 was found to be correlated with other inflammatory markers, suggesting its diagnostic value for inflammatory oral diseases. We also found that the PTX3 levels were lower in patients with OLP and BMS. ESR levels were elevated in the OLP and BMS groups, but CRP levels were not. Despite these associations, no correlation was found between PTX3 expression and other known clinical features of OLP and BMS. We suggest that PTX3 plays a role in the immunological and neurological pathways involved in the complex pathogenesis of OLP and BMS.

Foot-and-mouth disease (FMD), which affects cloven-hoofed animals, is economically important because of its highly contagious nature. FMD virus (FMDV), the causative agent of FMD, involves seven serotypes (O, A, Asia1, C, and SAT 1-3). Serotype Asia1 is unique to the Asian territory and is subdivided into nine genetic groups (G-I-IX) based on nucleotide variations in the VP1 sequence. Asia1 Shamir, the most representative Asia1 vaccine, is not highly protective against the Asia1/MOG/05 (G-V) lineage found in North Korea in 2007. Therefore, we investigated whether a chimeric virus strain (Asia1/MOG/Shamir), in which the VP4, VP2, and VP3 sequences of Asia1/MOG/05 were combined with the VP1 sequence of Asia1 Shamir, can simultaneously protect against both viruses. We determined the optimal viral growth conditions for the commercial utilization of this chimeric virus strain. Of the three types of cell culture media, the Cellvento medium resulted in the highest amount of antigen in the samples. The chimeric strain was proliferated in a small bioreactor to produce a test vaccine, and its immunogenicity was evaluated in pigs. The virus neutralization (VN) titer against the Asia1 Shamir virus was > 1/100 after the second immunization with the chimeric vaccine in pigs. In addition, a single dose of the test vaccine resulted in a VN titer of > 1/100 against the Asia1/MOG/05 strain. Taken together, our chimeric vaccine strain provided sufficient protection against the Asia1/MOG/05 and Asia1 Shamir viruses, suggesting its potential as a novel vaccine for both these strains.

본 연구는 코마개의 사용 여부에 따라 MRI 영상을 분석함으로써 숨 참기의 정확도를 향상할 도구로써 코마개가 실 효성이 있는지 검증하고자 하였다. 이를 위해 수검자에게 코마개가 없는 자연 호흡과 코마개를 사용한 구강 호흡 상태에서 호기 후 숨 참기를 지시하고 MRI 영상을 획득하였다. 영상은 2D 경사 자기장 에코 시퀀스로 획득하였고 초당 1장씩, 총 15장을 얻어 숨 참기 상태를 분석하였다. 숨 참기의 상태를 정량적으로 평가하기 위해 우측 폐 면적 을 측정하였다. 그리고 첫 번째 영상의 폐 면적을 기준으로 나머지 영상들에서 폐 면적의 절대 오차값을 구해 비교하 였다. 더불어 첫 번째 영상을 기준으로 나머지 영상들의 기하학적 유사도를 평가하기 위해 SSIM 값을 계산하였다. 실험 결과, 자연 호흡 상태에서 절대 오차는 평균 216.79 ㎟로 나타났다. 반면, 코마개를 사용한 구강 호흡의 경우 평균 55.94 ㎟로 나타나 자연 호흡과 비교하여 약 74.19% 감소하였다. SSIM 값은 자연 호흡 시 평균 0.7, 구강 호흡 시 0.76으로 나타나 기하학적 유사도가 약 6% 향상되었다. 이는 코마개 사용 시 호흡의 초기 상태를 잘 유지함 으로써 숨 참기의 정확도가 향상되어 능동적으로 호흡 상태를 조절할 수 있는 도구로써 충분한 가치가 있음을 증명한 다. 따라서 복부 MRI 검사에서 호흡에 따른 인공물을 개선하는 데 코마개가 도움을 줄 수 있으며 영상 개선 및 업무 효율을 높이는 도구로써 충분히 활용할 수 있다.