현행 형법과 공직선거 및 선거부정방지법 제18조에 따르면 선거일 현재 금고이상이 형을 선고받아 복역 중인 기결수와 집행유예를 선고받아 유예기간이 경과되지 않은 자들은 선거권이 없다. 다만 형이 확정되지 않은 미결수와 경범죄 처벌법상 구류처분을 받고 유치장에 구금 중인 자는 부재자투표를 통해 선거에 참여할 수 있다. 기결수에게 기본권적 요소인 참정권을 제한하는 것은 보통선거 원칙과 평등원칙 및 헌법에 규정된 과잉규제금지 원칙에도 위배될 가능성이 있다. 특히 2002년 6월 지방선거에 투표권을 행사하지 못하였다며 재소자 3명이 낸 위헌심판청구에 대해 헌법재판소가 기각결정을 내렸으나 수형자에 대한 선거권부여논란은 이후에도 계속 제기되고 있다. 모든 국민을 법적으로 평등하게 취급할 것을 요구하는 일반적 평등의 원칙은 헌법질서를 구속하는 법원칙의 하나이며 헌법과 모든 법령의 해석기준이 된다면서도 "정당한 이유, 합리적 근거가 있는 차별은 허용된다는 것이 학설과 판례의 입장"이라는 논지에서 수형자의 선거권의 제한을 긍정하는 입장과 형이 확정되지 않은 미결수용자와 수형자를 가리지 않고 재소자의 권리를 제한하는 것은 부당한 차별이라며 형이 확정된 수형자의 경우에도 선거권을 부여하는 나라도 있으므로 허용해야 한다는 입장도 있어 수형자의 선거권부여와 관련된 논란이 계속되고 있다. 수형자의 선거권 부여방안과 관련하여 관련 형사법 규정과의 저촉문제 등 관련 내용을 연구하고, 각국의 실태와 현황을 비교함으로써 우리나라 수형자의 선거권부여에 대한 제도적 방안을 연구하고자 한다.
Environmental Enrichment (EE) alone is not capable of enhancing the fine digit and the forelimb functions. Therefore, we applied modified constraint-induced movement therapy (mCIMT) under the influence of EE to assess its effect on promoting improved forelimb sensorimotor functions. Focal ischemic brain injury was produced in Sprague-Dawley rats (60 rats, 250±50 g) through middle cerebral artery occlusion (MCAO). Before MCAO induction, all rats were trained in modified limb placing tests and reaching tasks for 1 week. Then they were randomly divided into three groups: Group I: application of standard environment (SE) after MCAO induction (n=20), Group II: application of EE after MCAO induction (n=20), Group III: MCAO+EE, mCIMT and task-oriented training that was initiated at 10th day after MCAO induction (n=20). We also applied mCIMT (between 9 AM and 5 PM/daily) which included restraining the forelimb ipsilateral to the lesion using the 'Jones & Schallert' method. We assessed the change of modified limb placing, single pellet reaching test and the immunoreactivity of BDNF by immunohistochemistry (pre, 1st, 5th, 10th and 20th day). Group I showed no improved outcome, whereas group II and III significantly improved on the use of the forelimb and the immunoreactivity. The qualitative analysis of the skilled reaching test, of group III showed the greatest improvement in the fine digit and the forelimb function. These results suggest that EE combined with mCIMT is more functional in promoting enhanced fine digit and forelimb functional movements.
Cytokines play a vital role in the host immune response by regulating the development and function of im munocompetent ce11s One immunomodulatory agent that has received attention in oncology research recently is interleukin - lO(IL-lO). IL-IO inhibi ted tumor antigen presenta tion and induced energy in T lymphocytes that had been s timu lated by autologous MHC class II positive tumor ce11s Patients with head and neck cancer have been shown to exhibit profound irnmunosuppression. The mechani sm by which tumor ce11s alter immunological function in the host is poorly understood. Recently. production of biological active IL- IO was confirmed in ovar‘ian cancer, melanoma, skin cancel‘ & head and neck cancer, suggesting that IL- lO reduces the function of tumor infiltrating lymphocytes and contributes to the tumor growth. IL-IO expression has not been examined extensively in human oral cancer and has not yet been cla rified. The purpose of t his study were to investigate IL-IO mRNA and protein expression in NHOK, IHOK and oral squamous ce11 carcinoma(OSCC) ce11 line by RT-PCR and irnmunoslot blotting, and to apply its results to examine its thera peutic significance for oraJ cancers. Cultured NHOK showed a lower level of IL-IO mRNA and protein expression than cultured IHOK and HN 22 OSCC cell line under pre and postconfluency. HN 22 OSCC cell line under pre and postconfl u ency. showed the highest level of IL-I0 Cul tured IHOK showing a intermediate expression of IL- IO could be as a vaJ u a bJe marker for oral carci nogenesis ste p. During the terminal differentiation of a11 the ce11 lines, IL- IO ex pression was significantly unchangeabl e. IL- IO mRNA expression of a11 the ce11 lines was consistent with IL-10 protein expression. It suggested that IL- lO expression might play an important role in oral carcinogenesis and IHOK could be a valuable marker for oral carcinogenesis step. And aJso IL- 10 related gene may be future targets for gene discovery and possi bJy therapeutic intervention
This study was carried out to compare UCP2 polymorphism, dietary habits, and obesity index in normal and obese university students. The survey was carried out using self-questionnaires collected from the 126 normal and 60 obese university students. The results are summarized as follows. Breakfast was skipped in 43.7% of normal and 49.3% of obesity students and it appeared obese students eat faster than normal students. The percentage of weight control experience were 49.2 and 71.0 in the normal and obese students, respectively. Blood levels of lipid profiles(triglyceride, LDL cholesterol, and HDL cholesterol), hemoglobin, AST and ALT were anaylzed. In UCP2 genes, the frequency of deletion homozygote(DD) was 71.5%, heterozygote(DI) was 26.9% and insertion homozygote(II) was 1.6%. Plasma levels of triglyceride, total cholesterol, LDL cholesterol, and HDL cholesterol of normal students were 79.06, 172.25, 100.86 and 57.03 mg/dl, and those of obese students were 93.06, 173.22, 101.22 and 54.39 mg/dl, respectively. Blood parameters were in normal range in both group. Plasma triglyceride, total cholesterol and LDL cholesterol levels of obese students were higher than those of normal students. On the other hand, plasma HDL cholesterol levels of obese students were lower than those of normal students. Plasma levels of AST and ALT were in normal range in both group. However, AST and ALT levels of obese students were higher than that of normal students. Thus, it was recommended for them to have a nutritional education program to improve their dietary and living habits for obese students’health. Nutritional education program should also be organized practically and systematically.
한국형 잔디에 있어 병원성 (라지 팻치) 감염이 산화적 스트레스의 발현에 미치는 영향을 규명하기 위하여 라지 팻치에 감염된 잔디의 항산화 효소의 활성을 조사하였다. 처리 후 6일 동안 이틀간격으로 잎과 뿌리 시료에 대해 각각 분석하였다. 초기 2일 동안 SOD효소 활성은 처리 간 아무런 차이가 나타나지 않았으나 처리 후 6일차에는 대조구에 비해 라지 팻치에 감염된 잎에서 48% 뿌리에서 49% 각각 높게 나타났다. CAT 효소활성은 처리 후 2일간 잎에
Previous studies have shown that BMI-1026 is a potent inhibitor of the cyclin-dependent kinases (cdk). In cell culture, the compound also arrests G2/M strongly and G1/S and S weakly. Two key kinases, cdk1 (p34cdc2 kinase) and mitogen-activated protein (MAP) kinase (erk1 and 2), perform crucial roles during oocyte maturation and, later, metaphase II (MII) arrest. In mammalian oocytes, both kinases are activated gradually around the time of germinal vesicle breakdown (GVBD) and maintain high activity in eggs arrested at metaphase II. In this study, we examined the effects of BMI-1026 on GVBD and MII arrest in mouse oocytes. BMI-1026 inhibited GVBD of immature oocytes and activated MII-arrested oocytes in a concentration-dependent manner, with more than 90% of oocytes exhibiting GVBD inhibition and MII activation at 100 nM. This is approximately 500~1,000 times more potent than the activity reported for the cdk inhibitors roscovitine (~50 M) and butyrolactone (~100 M). Based on the results of previous in vitro kinase assays, we expected BMI-1026 to inhibit only cdk1 activation in oocytes and eggs, not MAP kinase. However, in our cell-based system, it inhibited the activity of both kinases. We also found that the effect of BMI-1026 is reversible. Our results suggest that BMI-1026 inhibits GVBD and activates MII-arrested oocytes efficiently and reversibly and that it also inhibits both cdk1/histone H1 kinase and MAP kinase in mouse oocytes.
본 논문에서는 풍동실험을 수행하여 3차원 산악지형에서의 풍속할증현상을 정량적으로 평가하고, 3차원 산악지형의 풍속할증현상에 대해 고찰하고자 한다. 풍속할증현상을 평가하기 위하여 건축구조설계기준에서 분류하고 있는 기울기에 준하여 다음의 , 그리고의 각각 다른 경사를 가진 5가지 산악지형모형을 제작하였다. 풍동 실험결과, 다양한 위치에서 풍속할증계수가 평가되었다 풍동실험결과를 바탕으로 풍속할증영역을 산정해 보면 수평방향의 영역은 산의 전체 지역, 수직방향의 영역은 산의 높이의 3.5배로 산정되었다. 풍속할증현상은 산의 정상부에서 크게 발생하였고, 경사 I은 57%, 경사 II는 75%, 경사 III은 79%, 경사 IV는 81%, 경사V는 61%의 풍속이 증가하였다. 또한 산의 정상에서 같은 거리에 있는 풍방향의 위치보다 풍직각방향의 위치에서의 풍속이 더 크게 평가되었고 풍직각방향의 경사시작면에서 의 풍속이 증가하였다.
Effects of Takju(Korean turbid rice wine) lees on noodle investigated by substituting Takju lees water extract powder for each 2% and 4% wheat flour in sample II and III, respectively. The lightness(L) of uncooked noodles was decreased, whereas that of cooked noodles was increased with increasing amount of extract added. Redness(a) and difference of total color(δE) were significantly increased according to the amount of extract added in uncooked and cooked noodles. Yellowness(b) of the noodles containing 2% Takju lees water extract powder was exhibited lowest values in uncooked and cooked noodles. In cooking property of noodles, turbidity of soup decreased in proportion to amount of extract added, 2% and 4% in sample II and III, respectively whereas the weight and volume of noodles were not significant than those of control. Tension of cooked noodle was highest in sample II and lowest in sample III. Texture profile analysis of cooked noodle showed an significant increase of hardness in addition of Takju lees water extract powder but not significant different in springiness, chewiness, adhesiveness. Cohesiveness was significantly lowest in sample II. The sensory evaluation showed that significant difference between noodles with 2% addition groups and control was not recognized but was recognized 4%. Therefore, based on cooking properties and sensory evaluation, Takiu lees water extract powder up to 4% could be substituted for wheat flour.
본 연구는 탄성균열문제를 신속하고 정확하게 해석할 수 있는 새로운 개념의 그리드(grid) 없는 유한차분법을 제시한다. 이동최소제곱법을 이용한 Taylor 전개식 구성을 통해 직접적인 미분계산 없이 근사함수와 그 미분을 손쉽게 계산한다. 그리드로 인한 절점 간의 종속성이 없어 해석영역 내의 불연속면 모델링이 용이하여 차분식 구성시 균열로 인한 불연속 효과를 고려하는 과정도 자연스럽다. 유한차분법에 근간을 두고 있어 지배 미분방정식을 직접 이산화하기 때문에 수치적분이 필요한 수치기법에 비해 계산속도도 빠르다. 모드 I과 모드 II 균열문제 해석을 통해 본 해석기법이 정확하고 효율적으로 응력확대계수를 계산할 수 있음을 보였다.
Z-M방법으로 한국 전역의 소나무림에 대한 식물사회학적 연구를 수행하였다. 소나무림은 크게 1군집, 3군락, 7아군락으로 구분되었다. 한국 소나무림의 분류체계는 다음과 같다. Rhododendro-Quercetalia mongolicae Kim 1990 I : Lindero-Quercion mongolicae Kim 1990 em. Kim 1992 A : Quercus mongolica-Pinus densiflora community A-1 : Typical subcommunity A-2 : Vaccinium koreanum subcommunity A-3 : Rhododendron micranthum subcommunity B : Quercus serrate-Pinus densiflora community B-1 : Typical subcommunity B-2 : Juniperus rigida subcommunity B-3 : Styrax japonica subcommunity B-4 : Eurya japonica subcommunity C: Saso-Pinetum densiflorae Yim et al. 1990 Camellietalia japonicae Oda et Sumata 1966 II : Ardisio-Castanopsion Miyawaki et al. 1971 D : Castanopsis cuspidata var. sieboldii-Pinus densiflora community 소나무-신갈나무군락은 한반도 중북부지역의 산지에 주로 분포하였으며, 소나무-졸참나무군락은 한반도 중부와 남부의 저산지와 구릉지에 넓게 나타났다. 소나무-제주조릿대군집은 제주도의 소나무림에서 조사되었다. 그리고 소나무-구실잣밤나무군락은 남서해안과 도서를 포함하는 난 온대역에 분포하였다.
In this paper, we describe a study on the relationship between neutral emulsion manufacture and hardening test of films. The hardeners were prepared by condensation of equimolar amounts of trichlorotriazine with benzene- or naphthalene-based amino or oxy acids at 0 to 5℃ and at pH 7, and used as hardening agents for gelatin. The hardening test of neutral emulsion layers was studied at pH 7.0. For example I(R=ONa) had strong hardening properties, I substituted with an aminobenzosulfonate moiety (R=NHC6H4-p-SO3Me where Me = K, Na) was a much weaker gelatin hardener, and when substituted with amino- or oxynaphthalene derivative (II, III) did not harden gelatin at all. Compound with 2 dichlorotriazine groups as IV exhibited hardening properties. The hardener can be used in neutral emulsion layer of film and showed good hardening effect.
2003년 하계 진해만의 수질개선을 위한 육상오염물질 삭감량을 산정하기 위해 생태계 모델을 적용하였다. 모델에 의해 재현된 진해만의 수질은 마산만 측의 내측에서 해양수질 등급 III을 상회하는 수준으로 나타났으며, 등급 II의 수질로 개선하기 위해서는 육상부하를 50% 삭감하는 것이 효율적인 것으로 나타났다. 진해만 전 해역을 목표수질인 화학적 산소요구량 (COD) 농도 2.0mg/L을 만족하는 조 건은 전체 육상부하의 70~90%를 삭감하거나, 전체 육상부하와 저질 용출부하의 50%를 동시에 삭감하여야 하는 것으로 나타났다. 해역 II등급을 유지하기 위해 삭감해야 할 양은 유기물과 영양염을 동시에 삭감할 경우, 유기물 (COD) 5,632kg/day, 용존무기인 481kg/day 및 용존무기질소 7,991kg/day이며, 이 때 오염부하량의 한계 즉, 환경용량은 화학적산소요구량 부하 13,112kg/day, 용존무기인 206kg/day 그리고 용존무기질소 3,425kg/day 이라고 할 수 있다.
본 연구에서는 제주마의 연령에 따라 Caslick's index와 번식률의 관계를 조사하고자 수행하였다. 제주마의 연령이 증가할수록 Caslick's index 역시 증가됨을 알 수 있었다. 연령이 어린 암말(세)에서는 평균 Caslick index가 45.4, 세에서는 72.5, 15세 이상은 72.5로 나타났다. Caslick's index에 따른 암말의 평균 연령은 Caslick's index 50 이하에서는 10.9세이고, 50이상 150 이하에
Insulin-like growth factor II (IGF2) and H19 genes are mutually imprinted genes which may be responsible for abnormalities in the cloned fetuses and offspring. This study was performed to identify putative differentially methylated regions (DMRs) of porcine H19 locus and to explore its genomic imprinting in in vitro fertilized (IVF) and somatic cell nuclear transferred (SCNT) embryos. Based on mice genomic data, we identified DMRs on H19 and found porcine H19 DMRs that included three CTCF binding sites. Methylation patterns in IVF and SCNT embryos at the 2-, 4-, 8~16-cells and blastocyst stages were analyzed by BS (Bisulfite Sequencing)-PCR. The CpGs in CTCF1 was significantly unmethylated in the 2-cell stage IVF embryos. However, the 4- (29.1%) and 8~16-cell (68.2%) and blastocyst (48.2%) stages showed higher methylation levels (p<0.01). On the other hand, SCNT embryos were unmethylayted (0~2%) at all stages of development. The CpGs in CTCF2 showed almost unmethylation levels at the 2-, 4- and 8~16-cell and blastocyst stages of development in both IVF (0~14.1%) and SCNT (0~6.4%) embryos. At all stages of development, CTCF3 was unmethylated in IVF (0~17.3%) and SCNT (0~1.2%) embryos except at the blastocyst stage (54.5%) of IVF embryos. In conclusion, porcine SCNT embryos showed an aberrant methylation pattern comprised to IVF embryos. Therefore, we suggest that the aberrant methylation pattern of H19 loci may be a reason for increased abnormal fetus after embryo transfer of porcine SCNT embryos.
Almost 20 years or more than 10 years have passed, Since Korea has received community service order into the juvenile justice system in 1988 and into the adult justice system in 1995. In this paper, the community service order system and practices during last 20 years are analysed and new directions of community service order in Korea are pursued. Recently Korean ministry of justice have started the missions to expand the scope of community service order and to diversify it. In this paper, the missions of the ministry of justice are also evaluated.
With these purpose the contents of this paper is as follows;
I. Introduction
II. The realities of community service oder in Korea
1. The provisions on community service order in the statutes
2. The practices of community service order
3. evaluation
III. The community service order as an alternative to detention at a workhouse
1. The fine system and the detention at a workhouse
2. The realities of the detention at a workhouse and its' problems
3. The plan of the ministry of justice
4. evaluation of the plan
IV. The community service order as a independent disposition
1. Suggestions
2. The draft of the revised Juvenile Act 2007
3. evaluation
V. Diversifying the community service order as a criminal sanction
1. The possibility of coexistence of probation order and community service order
2. The community service order as a condition of a suspended sentence
3. The community service order as a condition of parole
4. The community service order as a condition of a suspended prosecution
VI. Conclusion
A high resolution spectrum of PU Vul obtained at Bohyunsan Astronomy Observatory on April 9, 2004 is presented. At this phase, PU Vul was an emission-line star and its continuum was very weak. Emission lines of He II, H I, [Ne IV], [N II], [O III], [Ar V ] and [Fe VII] dominated the spectrum of PU Vul. Many of them exhibited hat-top profiles with strong and multi-peaked emissions on flat-tops of their profiles. Radial velocities for these lines were measured. Origins of the spectral lines are discussed in terms of the wind and the photoionization models.
In the autumn of 2000 and spring of 2001, field surveys were conducted to estimate the effectiveness of artificial reefs (type cube, 2×2×2m3) that were established in the four islands of Bangnyeong, Socheong, Daeyeonpyeong and Ganghwa in Kyonggi Bay, the west coast of Korea during 1995 and 1996. The condition of reefs was examined through SCUBA diving and a side-scan sonar. Much of the reefs in Daeyeonpyeong and Ganghwa area were buried in bottom sediment. Despite an intensive search in Bangnyeong area, even a cluster of reefs was not found and most of them seemed to be buried by sand waves. Thus an appropriate investigation on the sediment transport should be included in pre-assessment for the expected performance and protection of artificial reefs. Distribution of average CPUE in natural fishing ground (control) was estimated by bootstrapping simulation and possible comparison of CPUE between control and reef areas (treatment) were made in Bangnyeong and Socheong (Experiment I). Positive reef effect was detected in Socheong but CPUE of treatment in Bangnyeong was varied between or lower than the 99% CPUE confidence intervals of the control. Control/treatment abundance and biomass of fishes and invertebrates were tested by paired t-test and sign test (Experiment II). Only four cases among 22 showed significant positive effect. Based on the results, the cube artificial reef in Socheong was inferred as an affirmative one. Floor type was hypothesized to be one of the probable agents in determining the effectiveness of artificial reefs.
목적 : 척수손상 환자의 ASIA 운동능력 성취점수와 SCIMⅡ를 사용한 일상생활수행도와의 상관관계를 연구하여 일상생활수행 훈련 시 운동능력성취점수의 향상을 위한 효율적인 치료 방법의 선택 기준을 마련하고자 함이다.
연구방법 : 본 연구는 부산 시내에 거주하는 손상 후 6개월 이상인 42명의 척수손상 환자로 하였고 연구 기간은 2004년 12월부터 2005년 1월까지 이루어졌다. 평가도구는 ASIA의 운동능력 성취점수와 SCIMⅡ를 사용하여 운동능력 성취점수와 일상생활 수행도와의 상관관계를 알아보았다.
결과 : 척수손상환자 42명 중 손상 유형에 따라 3개의 군으로 나누어 비교하였다. 완전사지마비군에서 상지-전체 운동능력 성취점수와 일상생활활동과는 통계학적으로 유의한 상관관계를 보이고(p〈.01) 높은 상관관계가 나타났다(r=.90, r=.90). 불완전사지마비군에서는 상지-하지-전체 운동능력 성취점수와 일상생활활동과는 통계학적으로 유의한 상관관계를 보였고(p〈.05) 높은 상관관계를 보였다(r=.64, r=.81, r=.87). 하지마비군에서는 상지-하지-전체 운동능력 성취점수와 일상생활활동과는 통계학적으로 유의한 상관관계를 보였고(p〈.05) 보통의 상관관계를 보였다(r=-.49, r=.60, r=.61).
결론 : 이상의 결과로 볼 때 척수손상 환자에 대한 ASIA 운동능력 성취점수와 SCIMⅡ와는 상관관계가 있으므로 척수장애 재활의 지표를 확립하는 연구에 활용될 수 있을 것으로 생각된다.
The development of neonatal neuromuscular system is accomplished by the functional interaction between the spinal neurons and its target cells, skeletal muscle cells, and the intrinsic and extrinsic factors affecting this process. The aim of this study was to identify the effect of suspension unloading (SU) and neuromuscular electrical stimulation (NMES) upon the development of the neonatal spinal cord. For this study, the neonatal rats were randomly divided into three groups: a control group, an experimental group I, and an experimental group II. The SU for experimental group I and II was applied from postnatal day (PD) 5 to PD 30, and the NMES for experimental group II was applied from PD 16 to PD 30 using NMES that gave isometric contraction with 10 Hz for 30 minutes twice a day. In order to observe the effect of SU and NMES, this study observed neutrophin-3 (NT-3) and microtubule associated protein 2 (MAP2) immunoreactivity in the lumbar spinal cord (L4-5) at the PD 15 and PD 30. The results are as follows. At PD 15, lumbar spinal cord of experimental group I and II had significantly lower NT-3 and MAP2 immunoreactivity than control group. It proved that a microgravity condition restricted the spinal development. At PD 30, lumbar spinal cord of control group and experimental group II had significantly higher NT-3 and MAP2 immunoreactivity than experimental group I. It proved that the NMES facilitated the spinal development by spinal cord-skeletal muscle interaction. These results suggest that weight bearing during the neonatal developmental period is essential for the development of neuromuscular development. Also, the NMES on its target skeletal muscle can encourage the development of the spinal cord system with a full supplementation of the effect of weight bearing, which is an essential factor in neonatal developmental process.
본 연구의 I부에서 유도된 포화된 다공성매체의 파동 전파속도와 감쇠에 대한 이론해를 전산코드화 하였다. 본 논문에서는 작성된 전산코드를 사용하여 파동의 전파속도와 감쇠에 미치는 외력 주파수의 영향과 재료특성치의 변화의 영향을 파악하기 위한 파라미터연구를 수행하였다. 첫 번째 형태의 파동에 대한 압축성 파동 속도는 주파수-투수성 곱이 증가함에 따라 파동속도가 하한치로부터 상한치로 변이하는 영역에서는 주파수-투수성 곱의 함수로써 변화함을 보여주었다. 또한 파동의 전파속도 변화율이 가장 클 때 감쇠값이 최대가 됨을 알 수 있었다 두 번째 형태의 파동에서 파동의 전파속도는 주파수-투수성 곱이 작은 값을 가질 때 거의 0값을 나타내며, 주파수-투수성 곱이 큰 값을 가질 때 상한값을 나타냄을 알 수 있었다.