우리나라에 축산물을 수출한 국가들이 2022년과 2023년 에 제출한 2019-2022년 국가별 잔류물질검사프로그램(NRP) 자료를 바탕으로 축산물 유형별, 국가별로 잔류허용기준 을 위반한 동물용의약품과 환경오염물질의 현황을 분석하 였다. 가장 많이 위반된 잔류물질은 네오마이신 2 4 1건, 페 니실린G 183건, 겐타마이신 151건, 세프티오퍼 113건, 니카 바진 103건 등이였고 축산물별로는 소고기, 돼지고기, 가 금육, 우유, 계란 등의 순서로 나타났다. 잔류 위반이 가 장 많았던 소고기에서는 페니실린G, 세프티오퍼, 플루니신 , 네오마이신, 벤질페니실린, 멜록시캄, 플로르페니콜, 질 파테롤 등 전염병 치료에 사용되는 항생제와 해열제 및 성장 촉진에 사용되는 동물용의약품이 주로 검출되었지만 , 돼지고기에서는 성장촉진을 목적으로 사용되는 락토파민 과 항생제인 독시사이클린, 클로람페니콜, 벤질페니실린, 난드롤론, 티오라실, 스트렙토마이신 및 임신 촉진에 사용 되는 호르몬이 가장 흔하게 검출된 것으로 나타났다. 가 금육에서는 콕시듐증 치료에 사용되는 항생제인 니카바진 이 가장 많이 위반되었으며, 스트렙토마이신, 아미노글리 코사이드 항생제, 벤질페니실린, 독시사이클린 및 기타 항 생제가 그 뒤를 이었다. 동물용의약품의 잔류 위반은 많 은 국가에서 보고되고 있으나, 다이옥신과 PCB와 같은 환 경오염 물질의 잔류는 주로 유럽 국가에서 보고되었다. 국 가별 잔류물질의 차이는 각국에서 사육되는 가축과 사육 관리 방식의 차이에 의한 것으로, 소고기의 잔류 수준이 높은 것은 소는 다른 동물에 비해 질병 발생 시 개체별로 치료되기 때문일 것으로 추정된다. 본 연구 결과는 수입 축산물의 안전성 확보를 위하여 국가별, 축산물별로 중점 적으로 검사가 필요한 물질을 제시함으로써 매년 실시하 는 수입 축산물 잔류물질검사를 보다 과학적이고 효율적 으로 수행할 수 있는 기반을 제공하였다.

The aggressive scaling of dynamic random-access memory capacitors has increased the need to maintain high capacitance despite the limited physical thickness of electrodes and dielectrics. This makes it essential to use high-k dielectric materials. TiO2 has a large dielectric constant, ranging from 30~75 in the anatase phase to 90~170 in rutile phase. However, it has significant leakage current due to low energy barriers for electron conduction, which is a critical drawback. Suppressing the leakage current while scaling to achieve an equivalent oxide thickness (EOT) below 0.5 nm is necessary to control the influence of interlayers on capacitor performance. For this, Pt and Ru, with their high work function, can be used instead of a conventional TiN substrate to increase the Schottky barrier height. Additionally, forming rutile-TiO2 on RuO2 with excellent lattice compatibility by epitaxial growth can minimize leakage current. Furthermore, plasma-enhanced atomic layer deposition (PEALD) can be used to deposit a uniform thin film with high density and low defects at low temperatures, to reduce the impact of interfacial reactions on electrical properties at high temperatures. In this study, TiO2 was deposited using PEALD, using substrates of Pt and Ru treated with rapid thermal annealing at 500 and 600 °C, to compare structural, chemical, and electrical characteristics with reference to a TiN substrate. As a result, leakage current was suppressed to around 10-6 A/cm2 at 1 V, and an EOT at the 0.5 nm level was achieved.

L-asparaginase (ASNase) is a therapeutic enzyme used to treat acute lymphoblastic leukemia. Currently, the most widely used ASNases are originated from bacteria. However, owing to the adverse effects of bacterial ASNases, new resources for ASNase production should be explored. Fungal enzymes are considered efficient and compatible resources of natural products for diverse applications. In particular, fungal species belonging to the genus Trichoderma are well-known producers of several commercial enzymes including cellulase, chitinase, and xylanase. However, enzyme production by marine-derived Trichoderma spp. remains to be elucidated. While screening for extracellular ASNase-producing fungi from marine environments, we found four strains showing extracellular ASNase activity. Based on the morphological and phylogenetic analyses using sequences of translation elongation factor 1-alpha (tef1α), the Trichoderma isolates were identified as T. afroharzianum, T. asperellem, T. citrinoviride, and Trichoderma sp. 1. All four strains showed different ASNase activities depending on the carbon sources. T. asperellem MABIK FU00000795 showed the highest ASNase value with lactose as a carbon source. Based on our findings, we propose that marine-derived Trichoderma spp. are potential candidates for novel ASNase production.

Momordica charantia is therophyte vine plants. It is called natural insulin and contains carantine and vitamin C and so on. Momordica charantia is one of the representative subtropical crops as a functional crop, showing efficacy on improvement of diabetes, cancer, abdominal obesity and improvement of hypertension. According to climate change, Momordica charantia is growing cultivation area, but there is still insufficient research for insect pest occurrence and insecticides. Due to the lack of proper control measures, the damage caused by insect pests is increasing as the year goes by. This study was conducted to investigate the occurrence and damage of insect pests in Momordica charantia and utilize it as basic data for development of insect pest control technology. As a result, 5 orders of 13 species of insect pests were investicated. Among them, Aphis gossypii, Frankliniella intonsa, and Frankliniella occidentalis showed high density. In particular, Aphis gossypii showed the highest density in mid-May, also Frankliniella intonsa and Frankliniella occidentalis showed high density in the middle of June. The leaf damage caused by the larvae of Palpita indica was observed in late June. After mid July, the biginning of the high temperature period, the insect pest density decreased, but the damages caused by moths were severe.

We previously developed a novel attenuated Salmonella Typhimurium (S.Typhimurium) △lon△cpxR vaccine. This study was conducted in order to examine whether this vaccine could effectively protect growing piglets against Salmonella infection. Pregnant sows in group A were primed and boosted with the vaccine, whereas pregnant sows in group B received sterile PBS-sucrose. After farrowing, newborn piglets in groups A and B were challenged with a wild type virulent S. Typhimurium at three weeks of age. During the study, serum IgG titers of piglets in group A were significantly higher than those of piglets in group B (P<0.001). In addition, clinical signs were observed in 5.9% of piglets in group A during the entire experimental period after the challenge, while diarrhea was observed in 81.6% of piglets in group B. These results indicate that vaccination of the pregnant sows resulted in effective protection in piglets against Salmonella infection.

본 연구는 반추동물의 조사료 자원으로서 거대억새를 개발하기 위한 목적으로 수행되었다. 우리나라에서 새롭게 개발된 품종인 거대억새 1호를 완숙기 이후에 채취하여 in vitro 반추위 발효를 이용해반추위내 pH, 암모니아태 질소, 가스발생량, 휘발성 지방산 생성량 및 건물소화율을 조사하였으며,볏짚과 비교하여 평가하였다. 거대억새는 볏짚에 비하여 유의적으로 높은 반추위내 pH를 나타내었다(p<0.01). 암모니아태 질소의 경우 배양 12시간 이후에는 두 처리구간의 유의적인 차이를 나타내지 않았다 (p>0.05). 배양 6시간 이후 부터는 거대억새의 가스발생량이 볏짚에 비하여 유의적으로 낮게 나타났다 (p<0.05). 휘발성 지방산 생성량에 있어 acetate, propionate, butyrate, valerate 및 총생상량에서 볏짚이 거대억새보다 높게 나타났다. 그러나 iso-butyrate와 iso-valerate에서는 두 조사료원별 차이는 발견되지 않았다. 건물소화율에 있어 배양 12~24시간 사이의 거대억새 소화율이 볏짚에 비하여 유의적으로 나타났다. 결론적으로 거대억새의 이용성은 볏짚의 약 80% 수준인 것으로 나타났다.