오늘날 인과응보는 인과론이 아니라 아직도 종교적 가설로 남아있다. 이러한 인과응보가 객관화되기 위해서는 일반 자연법칙과 같이 원인으로서 작용과 결과로서 반작용이 자연계의 법칙으로서 반드시 물리학에서 정의된 법칙에 따라 예측이 가능해야만 한다. 따라서 학계에서는 임상 의사들이 임사체험국제학회(IANDE)를 중심으로 사례를 수집하거나 인위적 임사체험을 만들어서 근거자료를 확보하는 실험적인 연구가 진행되고 있다. 그러나 인과응보 메커니즘이 규명되기 위해서는 먼저 체험자의 조상이나 전생의 카르마가 원인 작용으로 확인되어야 하고, 이 카르마가 시간차를 두고 현재의 자손에게 부메랑으로 나타난 반작용의 결과라는 인과관계가 합리적 타당성과 논리적 근거자료와 함께 검증되어야 한다. 이에 따라 연구팀은 인과응보를 카르마의 부메랑 현상이라는 개념으로 정의하고, 1994년 6월부터 2017년까지 3월까지 23년 동안 한국과 일본을 중심으로 23년간 관련 자료를 수집하고 분석하여 인과응보에 관한 객관화 연구를 수행하였다. 이러한 장기과제의 연구결과에서 인과응보가 자연법칙으로서 에너지 보존법칙과 작용·반작용에 대한 뉴턴의 물리학적 법칙과 정확하게 일치하는 메커니즘을 밝히고 있다.

구조용 강재의 용접부는 강재(Base metal, BM), 용접모재(Weld metal, WM), 열영향부(Heat affected zone, HAZ)로 구성된다. 용접부를 구성하는 이들 세 부분의 구조적 성질은 서로 다를 것이므로, 강재의 용접부의 구조 거동은 BM, WM, HAZ로 구성된 복합체의 거동으로 고려할 수 있다. 본 연구에서는 용접부를 구성하는 BM, WM, HAZ 각각의 탄성계수를 나노압입으로 도출하고, 이들의 복합거동(composite action)을 고려한 용접부의 등가탄성계수(equivalent elastic modulus)를 산정하였다.

Insecticidal crystal toxins from the bacterium Bacillus thuringiensis (Bt) kill insects via a complex mode of action resulting in the creation of cytolytic pores in the membrane of midgut epithelial cells. These toxins are expressed in transgenic cotton and maize which have been adopted worldwide to control lepidopteran pests while reducing dependence on chemical insecticides. However, insect resistance to Bt toxins is increasing in certain key pest species. Beginning with Heliothis virescens, genetic studies in Bt-resistant Lepidoptera and Coleoptera have found mutations in ABC transporters. Cry1A, Cry1C, Cry2A, and Cry3B toxins each appear to target a different member of the ABC superfamily. These studies confirm the essential role of ABC proteins in Bt toxin mode of action. It is proposed that ABC proteins assist in the insertion of the toxin into the midgut epithelial membrane, a crucial step for which the mechanism has not been known in detail. Properties of ABC transporters suggest strategies to increase efficacy of Bt toxins and to delay the evolution of Bt toxin resistance in target insect pests.

“Action-oriented Approach (AA)” as a new teaching method has taken an important role in teaching and learning of French Education during past 10 years. However, even though the new teaching method is very welcome for educators, now it is the time that we have to consider whether the key principle and fundamental notion of this approach is suitable for our language education environments and is theoretically appropriate for education. For that, it is necessary that we have to carefully examine this “Action-oriented Approach” from two points of views. First of all, from the angle of foreign language education, we need to verify whether this new approach could be appropriately applied in teaching and learning of Korean foreign language education or not. Secondly, from a societal perspective, we need to examine how this method, considering language education as everyday life itself, can handle some critical perspectives in the point of “status in quo” of “AA”. It has been criticized that language education as everyday life itself can make learners in everyday life to unconsciously acquire maintaining the ‘status quo’ during actions such as “educational inequality”. It is expected that this kind of examination will suggest us an improved way of “AA” for more effective and appropriate practice of French Education, and will give us an opportunity to think about the better way of teaching and learning model by “AA” in Korea.

본 연구에서는 풍하중을 받는 건물에 설치된 다중거동 복합 감쇠장치(MHD)의 성능을 평가하고, MHD 예비설계 절차를 제안하였다. MHD에 의해 증가된 등가감쇠비와 그에 따른 건축구조기준에 근거한 응답저감계수를 예상한 후, 풍하중 스펙트럼에 의해 생성된 풍하중을 사용하여 20층 철골구조물에 대한 시간이력 해석을 수행하였다. 해석결과를 통해 얻어진 층변위 및 층간변위 평균 응답 감소율은 각각 0.585 및 0.525로, 이는 제안한 예비설계과정에서 추정된 응답감소계수 0.6과 거의 동일한 수치임을 확인하였다. 이로부터 제안된 방법을 사용하여 MHD의 제어효과를 효과적으로 평가할 수 있음을 확인하였다.

All games support the meaningful play, and each mechanism producing meaning is various. In mobile role-playing game, automation of in-game action standardizes movements of avatars and diversify combat challenges. Thereby players reinforce their avatars and make various repertoires so as to cope with different contents. Players predict the result of their own actions based on short-term, juicy feedbacks. In conclusion, mobile role-playing game has 'strategy' as its action mode while the unit time required for meaningful play is highly reduced. This analysis is significant in the sense that it was the first step toward integrated change of game play experiences.

The genetic algorithm (GA), one of the artificial intelligence (AI), is developed based on Darwin's theory of evolution, i.e., the mating of randomly selected objects. If more optimal solution is generated, then it is better to repeat the process of setting the optimum value. In this paper, the method of background music using the genetic algorithm is exploited when the computer game is executed each time. As a result, it has created several music that can be used in the actual game, and it could be confirmed that the other music that is created is different music when performed each time.

The purpose of this study is to analyze the characteristics of action research in the field of English education in Korea from 2001 to 2015 across 36 masters/doctoral theses and 21 articles from journals. The researcher specifically focuses on the following criteria: purpose, theme, methodology, differences between such characteristics across action research published in journals to that published in dissertations. According to the results, the number of action research dissertations has increased in recent years and the study suggests the number of action research continue its upward trend; action research in Korea has been more prevalent at the primary school level rather than at the secondary and university levels; and the proportion of mixed method in English education was much higher than that of the mixed research in education with a 43% mixed method proportion accompanied by 55% of qualitative research. The study concludes that action research in English education in Korea will become a more meaningful and feasible tool for practitioners’ inquiries, as it provides graduate students with applied experience in their current demanding school environment and writing assignments such as their thesis and research papers. The author suggests that the aforementioned factors enlarge the existential meaning of current graduate schools in Korea.

The human β-amyloid (Aβ) cleaving enzyme (BACE-1) is a target for Alzheimer’s disease (AD) treatments. This study was conducted to determine if acacetin extracted from the whole Agastache rugosa plants had anti-BACE-1 and behavioral activities in Drosophila AD models and to determine acacetin’s mechanism of action. Acacetin (100, 300, and 500 μM) rescued amyloid precursor protein (APP)/BACE1-expressing flies and kept them from developing both eye morphology (dark deposits, ommatidial collapse and fusion, and the absence of ommatidial bristles) and behavioral (motor abnormalities) defects. The RT-PCR and Western blot analysis revealed that the protective effect of acacetin on Aβ production is mediated by transcriptional regulation of BACE-1 and APP, resulting in decreased APP protein expression and BACE-1 activity, and reduced Aβ production by interfering with BACE-1 activity and APP synthesis, resulting in a decrease in the levels of the APP carboxy terminal fragments and the APP intracellular domain, and finally, resulting in a decrease in the number of amyloid plaques.

적극적 고용개선조치는 과거의 차별에 대한 보상과 왜곡된 불평등을 개선하기 위해 소수그룹에 우선 적으로 기회를 제공하기 위한 목적으로 미국에서 시작되었다. 우리나라는 남녀고용평등법 6차 개정 시, 성차별 해소와 여성우대를 위한 적극적 고용개선조치의 법적 근거를 마련하였다. 그 결과 2006년부터 500 인 이상 기업과 공공기관을 대상으로 적극적 고용개선조치가 시행되고 있다. 제도가 도입된 지 10년을 맞는 현 시점에서 볼 때, 적극적 고용개선조치의 파급력은 초기에 비해 미약해진 것으로 보이며, 제도의 효과성도 의문시되고 있다.이에 본 연구에서는 적극적 고용개선조치를 시행하고 있는 기업 1,945개소를 대상으로 적극적 고용개 선조치의 여성고용 효과를 분석하였다. 또한 여성고용이 기업성과에 미치는 경제적 효과는 이미 여러 선 행연구에서 고찰되었으므로, 이는 제외하고 여성고용이 기업성과로 연결되는 과정에서 기업의 인적자원 관리와 조직문화 전반에 걸쳐 나타나는 제도적 변화를 고찰하였다. 2006년과 2014년 두 시점을 기준으로 여성고용 우수 및 중간, 미달 기업의 제도를 비교함으로써 여성친화적 제도 및 가족친화적 제도가 여성고 용에 어떻게 작용하였는지를 살펴보았다. 마지막으로 적극적 고용개선조치가 여성고용률 제고와 여성고 용의 질적 개선에 기여하기 위해 제도적으로 어떤 변화가 필요한지를 살펴보기 위해 기업의 인사담당자 와 전문가집단을 대상으로 3차례에 걸쳐 델파이조사를 실시하였다. 조사결과를 바탕으로 적극적 고용개 선조치의 제도 개선방안을 제안하였다.

This paper reviewed the effect of job burnout on safety outcomes, and the moderating effect of safety climate in Korean Air Force. The prevalence of burnout in air force pilots has not been determined and reviewed. It is also unknown whether pilots’ burnout may affect their safety outcomes(safety action & compliance). The primary objective of this study was to determine the prevalence of burnout and it’s effect on safety outcomes. For cross-sectional survey, 910 questionnaires were sent to pilots in air force, and 722 questionnaires among them were returned effectively. The questionnaire was divided into 4 parts examining pilots’ demographic factors, job burnout, safety outcomes, and safety climates. To test and review proposed hypotheses, hierarchical multiple regression analysis was used. The results of statistical analysis appeared as follow; 1) EE(emotional exhaustion) and RPA(reduced personal accomplishment) effected negatively on safety action. 2) EE and RPA effected negatively on safety compliance. 3) EE effected more positively on safety action in higher SS(superior support) group than in lower SS group. 4) RPA effected more positively on safety compliance in higher SS(superior support) group than in lower SS group. 5) RPA effected more positively on safety action in higher CW(coworker support) group than in lower CW group.

Recently, the Ministry of Employment and Labor Management is a trend to strengthen all men death rate than the accident rate. Points reduction in the accident rate change orders related to credit rating score to +2 points in his plans as part of +1 point. In addition, according to the fancy linger RISK treatment in the event of a disaster site and fiction treatment to achieve accident-free during processing the scene interspersed with equity issues have been raised. In general disaster for the problem in the first two cases occurs when abnormal process according to the disaster site manager positions dismissal policy, each division headquarters itself, interspersed disasters performance compared to processing in accordance with the refrain, processing expenses in accordance with the composition of untreated industrial accident, costs and burdens partners FTC , there is a possibility that the issues raised, such as the Ministry of Employment and Labor. In response to domestic social practices focused on the construction site practices and prevention measures should be evaluated with respect to what.

The ecdysis behavioral sequence in insects is a classic fixed action pattern (FAP) initiated by hormonal signaling. Ecdysis triggering hormones (ETHs) release the FAP through direct actions on the CNS. Here we present evidence implicating two groups of central ETH receptor (ETHR) neurons in scheduling the first two steps of the FAP: kinin (aka drosokinin, leucokinin) neurons regulate pre-ecdysis behavior and CAMB neurons (CCAP, AstCC, MIP, and Bursicon) initiate the switch to ecdysis behavior. Ablation of kinin neurons or altering levels of ETH receptor (ETHR) expression in these neurons modifies timing and intensity of pre-ecdysis behavior. Cell ablation or ETHR knockdown in CAMB neurons delays the switch to ecdysis, whereas overexpression of ETHR or expression of pertussis toxin in these neurons accelerates timing of the switch. Calcium dynamics in kinin neurons are temporally aligned with pre-ecdysis behavior, whereas activity of CAMB neurons coincides with the switch from pre-ecdysis to ecdysis. Activation of CCAP or CAMB neurons through temperature-sensitive TRPM8 gating is both necessary and sufficient to trigger ecdysis behavior. Our findings demonstrate that kinin and CAMB neurons are direct targets of ETH and play critical roles in scheduling successive behavioral steps in the ecdysis FAP. Furthermore, temporal organization of the FAP is likely a function of ETH receptor density in target neurons.

Beyond transnational litigation which seeks to hold corporations accountable for their misconduct overseas through judicial recourse, the risk of human rights abuses should be mitigated by embedding good practices locally through domestic laws and policies. The United Nations proposed Guiding Principles for transnational and other businesses for this purpose in 2011. It has been suggested that National Actions Plans should give effect, or at the very least policy coherence, to the international standards enshrined in the Guiding Principles. This article argues that, properly devised, such plans are invaluable, and can help to reinforce regional imperatives under international law. In Southeast Asia, particularly, the prospect of corporate accountability should be measured by existing or emergent regulatory norms in ASEAN, a regional bloc that aims to achieve parity of rules and regulations across the ten countries through economic integration.

목적 : 본 연구는 삼킴장애를 동반한 뇌졸중 환자에게 동영상 동작모방이 삼킴기능에 미치는 영향을 알아 보고자 하였다. 연구방법 : 2013년 5월부터 12월까지 부산광역시 소재의 P병원에 뇌졸중으로 내원한 환자 중 삼킴장애를 동반 한 뇌졸중 환자 16명을 동영상 동작모방군과 대조군으로 무작위 할당 하였다. 동영상 동작모방군은 동작관찰 과 함께 동영상에서 제공되는 동작을 모방하였고, 반면 대조군은 풍경으로만 구성된 동영상을 5분간 관찰하 였다. 중재에 사용된 동영상은 정상인이 음식을 먹는 장면으로 구성 되었으며, 총 시간은 5분이다. 1일 1회, 주 3회, 4주간 치료시작 전 실시하였으며, 중재이외의 모든 치료는 두 군에게 동일하게 제공되었다. 중재의 효과를 검증하기 위해 중재 전, 후에 연식, 고형식, 액상식에 대한 비디오 투시 조영검사(Videofluoroscopic Swallowing Study; VFSS)를 실시한 후 기능적 삼킴장애척도(Functional Dysphagia Scale; FDS), 삼킴장 애 임상척도(Clinical Dysphagia Scale; CDS), 구강이동시간(Oral Transit Time; OTT)을 조사하였다. 결과 : 집단 내 분석 결과 동영상 동작모방군은 모든 척도에서 중재 전에 비해 중재 후 모든 식이유형에서 유의한 차이를 보였다(p<.05). 또한 집단 간 분석 결과 FDS가 모든 식이유형에서 대조군보다 동영상 동작모방군이 통계학적으로 향상됨을 알 수 있었다. 결론 : 삼킴장애 재활치료에 동영상 동작모방을 적용하는 것이 뇌졸중 환자의 삼킴기능을 향상시키는데 효 과적임을 확인하였다.

This study evaluated and compared the effectiveness on upper motor extremity function between proprioceptive neuromuscular facilitation which has been frequently used in clinical practice, and action observation training in terms of improving upper motor extremity function. A study with a single-subject design (A-B-C-A') was conducted with a patient who was diagnosed with left hemiplegia. A repeated-measure analysis was conducted to assess results of the Wolf Motor Function Test (WMFT), Box and Block Test (BBT), and grip and pinch strength test performed daily in the study for 4 weeks. The results of the analysis indicated that the WMFT score, BBT score, grip strength, and pinch strength were improved from 29.60 to 39 (24.10%), from 1.67 to 4.93 each (EA) (66.22%), from 2.06 to 2.66 libras (lbs) (22.61%), and from 1.57 to 1.93 lbs (18.94%), respectively, from the baseline period to treatment period B. The values were improved from 29.60 to 42.20 (29.86%), from 1.67 to 7 EA (76.21%), from 2.06 to 3.47 lbs (40.57%), and from 1.57 to 1.67 lbs (6.12%), respectively, from the baseline period to treatment period C. From treatment period B to treatment period C, the WMFT score, BBT score, and grip strength were improved from 39 to 42.20 (7.58%), from 4.93 to 7 EA (29.56%), and from 2.66 to 3.47 lbs (23.20%), respectively, but pinch strength was decreased from 1.93 to 1.67 lbs (15.83%). In conclusion, proprioceptive neuromuscular facilitation and action observation training both have positive effects on upper extremity motor function. However, we suggest that the posttreatment effect of action observation training was better than that of proprioceptive neuromuscular facilitation.

In recent years, the globalization has raised the interest in the overseas experiential learning. Overseas experiential learning has been playing an important role by learning from various cultures which enables the students to achieve the global insights and leadership. However, the regulations have not been properly established, and Ministry of Education tend to recommend not to travel abroad without a special purpose. The results were found that teachers seek the exchange program with the local students in the partner country, and, overall, the cost-effectiveness was relatively low. Also, with the fact that the revisit was not recommendable, the satisfaction of the previous activities has been questioned. Teachers agreed with the critical points on career development of middle school and high school students, and positively rated the suggested prototype of oversea experiential learning based on career education.

본 글은 거울신경세포시스템에 대한 신경학적 기전에 대하여 알아보고 이에 근거한 동작관찰훈련에 대한 문헌 고찰을 통해 임상에서 신경계환자의 재활치료에 있어 치료적 접근법으로써 사용될 수 있음을 제안하기 위해 작성되었다. 거울신경세포시스템은 특정한 동작의 움직임이나 다른 개체가 움직이는 것을 관찰할 때 활동하는 신경세포를 말하며, 인간의 운동앞이랑, 아래마루엽과 아래이마이랑, 마루엽영역, 위 관자엽고랑을 포함하는 배쪽운동앞겉질에 존재한다고 알려져 있다. 이러한 신경학적 근거에 따라 사용되 고 있는 치료방법에는 동작관찰훈련이 있는데, 동작을 관찰하고 관찰한 동작을 다시 모방하여 반복적으 로 훈련하는 방법이며, 다른 사람의 행동을 관찰함으로써 형태와 동작을 이해하고, 선택하고 모방하여 운동학습의 단계까지 이르는 훈련방법을 말한다. 현재 동작관찰훈련의 치료적 효율성과 임상적용에 대해 서는 관련 연구들이 진행되고 있으며, 해당 연구들에서 기능향상의 효과가 있음이 보고되고 있다. 이러 한 동작관찰훈련방법은 불가능한 움직임보다는 가능한 움직임, 즉 실제 사람의 손의 움직임을 관찰하는 직접적인 방법이나 목적지향적인 과제에 대해서 관찰을 시킬 때 더욱 활성화 시킬 수 있다. 이러한 거울 신경세포에 근거한 동작관찰훈련은 치료적 측면을 떠나 퇴원 후 가정에서도 지속적으로 수행하기 용이 하고, 경제적으로도 비용절약에 효과적인 방법이라 할 수 있겠다. 따라서 본 글에서는 이러한 거울신경 세포시스템에 대한 신경학적 근거에 대해 알아보고 그와 함께 거울신경세포시스템에 근거한 동작관찰훈 련을 적용한 연구를 고찰함으로써 신경계재활치료영역에 있어서 그 효율성과 치료적 적용 가능성에 대 해 알아보고자 한다.