This study was conducted to analyze relationships between depression indices, mini nutritional assessment scores, and nutritional quotients among 80 elderly in Yangpyeong-gun and to identify factors that help prevent depression and malnutrition. Nutrition assessment scores were low in the high-risk group (PHQ-9 score 10), and nutritional quotient scores were lower in the high-risk group than in the normal group (PHQ-9 score 4). Interestingly, the consumption frequencies of fruits, eggs, and nuts were low in the high-risk group, and subjective health awareness, dental condition, and sleep were poorer. The total PHQ-9 score was correlated with malnutrition, body mass index, calf circumference, weight change, independent daily living, reduced meal amount, water intake, and the need for help when eating. Analysis of correlations between items of the PHQ-9 and nutritional status evaluation indices showed that a self-perceived feeling of depression, low energy, difficulty controlling sleep or appetite, negative thoughts (e.g., failure, disappointment), and difficulty concentrating were negatively correlated with total nutritional status scores. These results show that attention is required when food or water intake decreases and that deviation from normal sleep and appetite cycles flags the need to prepare guidelines to prevent depression.

본 연구는 제5차 국가산림자원조사(2006-2010)에서 조사된 편백을 대상으로 흉고직경에 따른 수고 생장곡선식과 초기 수고생장 모델을 개발하여 편백의 초기 생장특성을 고려한 합리적인 산림경영계획 수립에 필요한 기초자료를 제공할 목적으로 실시하였다. 연구자료는 제5차 국가산림자원조사 자료 중 편백 표준목 353본에 대한 수고, 흉고직경, 연륜생장 자료를 이용하였다. 흉고직경에 따른 수고 생장곡선식은 Petterson 식, Log 식, Michailow 식을 이용하여 개발하였으며, 연령에 따른 초기 수고생장 모델은 Chapman-Richards 식, Gompertz 식, Schumacher 식을 이용하여 개발하였다. 본 연구 결과, 모델 검정을 통하여 흉고직경에 따른 수고 생장곡선식은 Petterson 식이 가장 적합한 것으로 나타났으며, 초기 수고생장 모델은 Gompertz 식이 가장 적합한 것으로 나타났다. 본 연구에서 개발한 초기 수고생장 모델을 그래프로 나타낸 결과 편백은 13년생일 때 연간 수고생장량이 0.54m로 가장 많은 것으로 나타났다. 본 연구 결과는 편백의 생장 특성 관련 연구에 활용할 수 있을 뿐 아니라 초기의 편백 조림지에 대하여 합리적인 산림경영계획 수립에 유용한 기초자료가 될 것으로 기대된다.

Volcanic seawater has been naturally filtered and purified by volcanic rock layers. It contains abundant minerals such as calcium, magnesium, and iron. This study investigated the genotoxicity of calcium from Jeju lava seawater (CJLS). We performed bacterial reverse mutation assay, chromosomal aberration assay, and mammalian micronucleus test at up to 5,000 g/plate concentrations with or without metabolic activation to determine the CJLS genetic toxicity. None of these tests showed any mutagenic potential. The bacterial reverse mutation assay showed that the CJLS did not induce mutagenicity in Salmonella typhimurium TA98, TA100, TA1535, TA1537, and Escherichia coli WP2uvrA with or without metabolic activation of the S9 mixture. The oral administration of CJLS also did not significantly increase the number of micronucleated polychromatic erythrocytes or the mean ratio of polychromatic to total erythrocytes. Additionally, CJLS did not cause a significant chromosomal aberration in CHL cells in the presence or absence of S9 activation. Therefore, CJLS could be considered as a reliable and safe functional food ingredient.

This study was a qualitative investigation into the food security and food variety among the rural elderly. For the qualitative data collection, nineteen elderly people who lived in Yangpyeong-gun were interviewed individually. Food security and variety was evaluated based on accessibility and affordability. The participants seemed to have difficulty preparing their own meals and eating with their families or others. The frequency of vegetable intake was found to be high, as vegetables were available through cultivation. However, in terms of diversity, the intake of meat and milk, which are sources of protein and calcium, was found to be significantly low. This has to do with very poor physical accessibility. A lack of nutrition education was identified as the biggest reason for not following dietary therapy despite having a pre-existing disease condition. Therefore, for the elderly in Yangpyeong-gun, it is suggested that a basic nutrition policy for food supply that can increase their actual intake is more essential than education on cooking and nutrients. Moreover, periodic nutrition education or a regular counseling system for dietary therapy through local public health centers may help improve the health of the elderly.

Drawing from the uses and gratification theory (UGT), the study intends to investigate audiences’ motivation to watch Livestream and its influence on subscription and donation. The roles of viewers’ parasocial relationships and identification with live streamers were also examined. The results also indicate the presence of a mediation effect.

This study evaluates the gastroprotective effect of cabbage extract with sulforaphane content of 5.19 mg/L and Smethylmethionine content of 469.28 μg/L. In vitro, the lipopolysaccharide (LPS)-treated group had an increased NO activity compared to the normal group, and the concentration of NO was reduced when the cabbage extract was treated in the dose manner. The level of IL-6 induced by LPS was dose-dependently reduced when the extract was treated. The cabbage extract concentration was orally administered in rats at 5.75 mg/kg, 11.5 mg/kg, and 23 mg/ kg, and the inhibitory effect on gastric damage by HCl-ethanol was observed. Histological analysis exhibited mucosal erosion in the gastritis model compared to the normal group, while the ameliorating effect of the generated erosion was observed in the cabbage-treated group. The histamine concentration was significantly increased in the gastritis-induced animal model, and the histamine concentration was decreased in the 23 mg/L-treated group of cabbage extract. In conclusion, the results of this study suggest that cabbage extract not only down-regulates cytokines in vitro, but is also directly involved in histamine secretion in an animal model of gastritis; therefore, cabbage extract can help inhibit gastrointestinal disorders by improving the protective barrier.

The purpose of this study was to investigate the sensory properties and consumer preference of Korean menu for different cooking water. Mineral water (MW) and bottled water (BW) were used as cooking water. Sensory attributes were derived by qualitative evaluation, and preference tests were conducted using the duo-trio test and 9 point likert scale. Mechanic properties were also evaluated. For the sensory attribute, properties such as tough, greasy, glossy, salty were derived when cooked with MW. For consumer preference, overall taste, aftertaste, and degree of sticky of bap were significantly higher in MW than in BW (p<0.05). The preference for the rich flavor of sagol broth (p<0.05) was significantly higher in MW than in BW. Preference for taste and flavor of omija-hwachae was higher than BW (p<0.01). In the mechanical properties test, food material boiled with MW showed higher property for cohesiveness and gumminess (p<0.05). In conclusion, cooking water with high calcium and magnesium content has been evaluated to enhance the palatability of Korean menus such as bap and sagol broth, and thus it is considered that various Korean menus can be applied. This suggests that dietary calcium and magnesium intake can be increased by using cooking water with a high calcium and magnesium content.

Functional foods for health are often consumed among adolescents. To investigate functional food usage, this study surveyed 326 students aged 14-16. 56.3% of the subjects answered that they were interested in health. More than 76% of the subjects thought themselves to be very healthy. Users of functional foods made up 56.7%, and among all types of functional food, probiotic supplements were taken most frequently, followed by nutritional supplements>red ginseng products>enzyme containing products. Most users of functional food got the information on functional food through family (71.3%). 50.3% of users experienced the effectiveness of the functional food when they supplemented. After use, repurchase intent was 58.1%. In order to investigate the relationship between academic stress and functional food usage, groups were classified as stressful (n=124), intermediate (n=122), and low stress (n=84) according to self-perception about stress. There was no significant difference in the intake of functional foods according to academic stress. However, in the intermediate stress group, academic stress index was improved in the users of functional foods. In conclusion, the results of this study can be used to develop functional foods in the future, possibly helping to prepare nutrition education materials, reducing academic stress among adolescents with middle stress.

Curcumin have various health-beneficial properties in numerous studies. However, its bioavailability is low due to its limited intestinal uptake and rapid metabolism. This study aimed to evaluate the pharmacokinetics of newly developed sub-micron particle curcumin with increased water dispersibility (Theracurmin® CR-033P). Plasma curcumin levels were measured at 0, 1, 2, 4, 8 h after Theracurmin® CR-033P intake using high-performance liquid chromatography. For analyzing pharmacokinetics of Theracurmin® CR-033P, eighteen healthy subjects were recruited and received Theracurmin® CR-033P at a single oral dose containing curcumin 30 mg. Cmax was 28.14 ng/ml, and the area under the curve for 8 h was estimated to be 104.36 ng/ml. Based on the area under the plasma concentration (AUC), the bioavailability of sub-micron particle curcumin was higher 22-, 35-, 28-fold than native curcumin in men, women, and all subjects, respectively. For comparing by formulation, seven healthy subjects were recruited and received two type of treatment: (1) existing dosage form 300 mg (contained curcumin 30 mg) × 3 capsule, (2) high dosage form 300 mg (contained curcumin 90 mg) × 1 capsule + placebo 300 mg × 2 capsule. In the cross-over study, there was no significant differences in Cmax and AUC of plasma curcumin. In conclusion, submicron particle curcumin with increased water dispersibility significantly improved its oral bioavailability and women absorbed curcumin more effectively than men. Different formulation of Theracurmin® CR-033P has shown equivalent to the reference in terms of pharmacokinetics.

Backgoound : This study was conducted to evaluate the quality variation of Ixeris dentata on the antioxidant contents and antioxidant activities according to the different producing area. Methods and Results : The samples were extracted with 70 % EtOH and then analyzed for total flavonoid contents, polypenol contents, DPPH radical scavenging activity, and ABTS radical scavenging activity. Luteinol 7-O-β-D-glucoside, an index component of the Ixeris dentata, was analyzed by HPLC. The leafs of Ixeris dentata in Jinan had the highest concentration of polyphenols (23.91 ㎎/g), followed by Jinbu (22.63 ㎎/g) and Eumseong (21.36 ㎎/g). Flavonoid content was highest in Jinan (15.27 ㎎/g), but there was no significant difference between Jinbu (14.05 ㎎/g) and Eumseong (13.99 ㎎/g). The contents of luteinol 7-O-β-D-glucoside were confirmed in Jinan (0.68%), Jinbu (0.49%) and Eumseong (0.36%), respectively. Conclusion : The comparison of antioxidant contents and antioxidant activities of Ixeris dentata according to the different producing area, Jinan was had the highest concentration, followed by Jinbu and Eumseong. Our results showed that the content of luteoline-7-D-glucoside varied among the different producing area.

The use of human mesenchymal stem cells (hMSCs) in cell-based therapy has attracted extensive interest in the field of regenerative medicine, and it shows applications to numerous incurable diseases. hMSCs show several superior properties for therapeutic use compared to other types of stem cells. Different cell types are discussed in terms of their advantages and disadvantages, with focus on the characteristics of hMSCs. hMSCs can proliferate readily and produce differentiated cells that can substitute for the targeted affected tissue. To maximize the therapeutic effects of hMSCs, a substantial number of these cells are essential, requiring extensive ex vivo cell expansion. However, hMSCs have a limited lifespan in an in vitro culture condition. The senescence of hMSCs is a double-edged sword from the viewpoint of clinical applications. Although their limited cell proliferation potency protects them from malignant transformation after transplantation, senescence can alter various cell functions including proliferation, differentiation, and migration, that are essential for their therapeutic efficacy. Numerous trials to overcome the limited lifespan of mesenchymal stem cells are discussed.