In this work, we investigated the photo-degradation performance of MnO2-SiC fiber-TiO2 (MnO2-SiC-TiO2) ternary nanocomposite according to visible light excitation utilizing methylene blue (MB) and methyl orange (MO) as standard dyes. The photocatalytic physicochemical characteristics of this ternary nanocomposite were described by X-ray diffraction (XRD), scanning electron microscopy (SEM), tunneling electron microscopy (TEM), ultraviolet-visible (UV-vis), diffuse reflectance spectroscopy (DRS), electrochemical impedance spectroscopy (EIS), photocurrent and cyclic voltammogram (CV) test. Photolysis studies of the synthesized MnO2-SiC-TiO2 composite were conducted using standard dyes of MB and MO under UV light irradiation. The experiments revealed that the MnO2-SiC-TiO2 exhibits the greatest photocatalytic dye degradation performance of around 20 % with MB, and of around 10 % with MO, respectively, within 120 min. Furthermore, MnO2-SiC-TiO2 showed good stability against photocatalytic degradation. The photocatalytic efficiency of the nanocomposite was indicated by the adequate photocatalytic reaction process. These research results show the practical application potential of SiC fibers and the performance of a photocatalyst composite that combines these fibers with metal oxides.

본 연구는 무늬 식물의 발현 양상을 확인하기 위해 Peperomia 속의 무늬가 없는 P. rotundifolia와 무늬 발생 양상이 서로 다른 P. argyreia, P. obtusifolia ‘Variegata’, P. marmorata ‘Pink Lady’4종을 대상으로 잎의 형태적 특성과 색소 구성 특성을 비교 분석하였다. 연구 결과, P. argyreia은 배경색과 무늬색의 색차(△E)가 크게 나타났지만, 단면 세포에서는 엽 록소가 고르게 분포하고, 색소 구성에서 무늬 유무에 따른 차 이가 없었다. 반면, c ‘Variegata’는 색소 구성에서 배경색과 무늬색 사이에 유의적인 차이를 보였다. 단면 세포에서도 엽 록소 분포의 차이가 뚜렷이 관찰되었다. 붉은 색의 무늬를 가 진 P. marmorata ‘Pink Lady’는 안토시아닌을 포함하고 있 어, 다른 품종들과는 다르게 색소체 생성에 따른 무늬 발현 양 상을 보였다. 결론적으로, P. argyreia는 표피의 공기층에 의 해 무늬가 발현되는 구조적 패턴을 가지며, P. obtusifolia ‘Variegata’와 P. marmorata ‘Pink Lady’는 엽록소와 카르 티노이드, 안토시아닌 등 색소적 특징에 의해 무늬를 발현시 키는 것으로 확인되었다. 이처럼 품종 특이적으로 다른 무늬 발생 양상을 가진 식물은 관상 가치를 유지하기 위한 광환경 이 다르게 요구될 것으로 판단된다.

Traditional medicine and herbal remedies are gaining popularity worldwide, comprising a significant portion of healthcare research, advancements, and market demand. Growing scientific evidence supports their substantial efficacy as pharmaceutical ingredients and dietary supplements in preventive healthcare. When developing pharmaceuticals, it is crucial to ensure that ingredients are free from side effects and toxicity in order to prioritize safety. Geckos, known as shou gong, are a diverse group of lizards that are widely utilized for treating various diseases in Korean Medicine. This study was conducted to assess the potential acute toxicity of a water extract Gekko gecko by a single oral dose in Sprague-Dawley rats. Twenty rats of each sex were randomly assigned to four groups (5 rats each). Test articles were administrated once by oral gavage to rats at dose levels of 0, 500, 1,000, or 2,000 mg/kg body weight. Mortality, changes of body weight, and clinical signs of gross observation were monitored for 14 days after dosing. At the end of a 14-day observation period, all animals were sacrificed and complete macroscopic and hematological examinations were performed. There was no dead animal or test article-related effect on clinical signs, body weight, or gross finding. Other specific changes were not found between control and treated groups in hematology. Results showed no adverse effect at a dose of 500, 1,000, or 2,000 mg/kg in rats. The minimal lethal dose was considered to be over 2,000 mg/kg body weight in rats.

In insects, the glutathione S-transferase is initiated in both the detoxification process and the protection of cellular membranes against oxidative damage. In this study, we identified the open reading frame (ORF) sequence of GST-iso1 and 2 from Tenebrio molitor (TmGST-iso1 and 2). To investigate the expression patterrns of TmGST-iso1 and 2 in response to herbicide, 0.06, 0.6, and 6 ㎍/㎕ of butachlor (FarmHannong, Seoul, South Korea) was challenged into T. molitor larvae, resulting that the TmGST-iso1 were highly induced at 3 and 24 h-post injection. Whereas, the highest expression of TmGST-iso2 was detected at 24 h after treatment. This study may contribute to basic information about the detoxifying activities of T. molitor.

It is well known that the JNK pathway regulates AMP production against pathogenic infection in both vertebrates and invertebrates. Tenebrio molitor hep (Tmhep) is an homolog of MAP kinase kinase in mammals. Here, we investigate the immunological function of Tmhep in responses in microbial infection using RNA interference technology. The results showed that silencing of Tmhep increased the larval mortality against microbial challenge, as well as reduced AMP production compared to the control group (dsEGFP-treated group). Conclusively, Tmhep plays an critical role in antimicrobial defense in T. molitor larvae.

The baculovirus expression system (BES) utilize the p10 or polyhedrin promoter, a very late promoter that exhibits strong transcriptional activity primarily at the end of viral infection, to produce useful recombinant proteins. The burst sequence of the very late promoter is essential for strong transcription, and VLF-1 is a transcription factor that binds specifically to the burst sequence, and it has been reported that it can regulate the amount and timing of expression of protein by the very late promoter. Recently, a VLF-1 constitutively expressing cell line was constructed to increase the production of the target protein, but the effect was minimal. In this study, to find the optimal VLF-1 expression conditions to increase target protein production efficiency, we controlled the expression of VLF-1 through various promoters and evaluated the target protein expression efficiency by the p10 promoter accordingly.

나리(Lilium spp.)는 절화, 정원 식물 및 화분 식물과 같은 관상용 가치로 인해 가장 중요한 화훼 작물 중 하나이다. 나 리는 연작으로 인한 환경 스트레스에 민감하며, 환경 스트레 스의 원인 중 하나로는 염 스트레스가 있다. 본 연구는 분홍 색 오리엔탈 나리 'Medusa', 'Lake Carey', 'Ovada'의 생 육 시기별 염스트레스에 따른 표현형 및 색 관련 화합물 함 량 변화를 조사하였다. 염 처리는 생육 시기에 따라 다양한 처리기간(무처리, 발아 전, 발아 후, 전체 생육기간)에 주 1 회 염(8dS･m-1)처리를 실시하였다. 생육 시기별 염스트레스 에 의한 개화의 차이가 있었지만, 전체 생육기간동안 염 스 트레스 처리시 모든 품종에서 개화가 이루어지지 않았다. 염 스트레스 처리 시기에 따라 초장과 꽃의 크기가 감소율이 달 랐으며 'Medusa', 'Lake Carey'는 발아 후 염 처리에서 정 상 개화하였다. 또한, 염스트레스는 꽃과 같은 식물에서 생성 되는 색 관련 화합물인 페놀과 플라보노이드 함량도 시기별 로 차이가 있었다. 품종마다 차이는 있지만, 발아 전이 발아 후 염 처리보다 총 페놀과 총 플라보노이드 함량이 더 낮은 것을 확인하였다. 이 결과는 생육 시기에 따라 염 스트레스 에 의한 나리의 표현형과 화색 관련 화합물의 함량의 변화에 차이가 있었으며 생육초기 염스트레스에 의한 피해가 높은 것으로 판단된다.

KINAC is trying to build a comprehensive aerial view of the nuclear material balance to predict North Korea’s weapons-grade nuclear material production capacity. We are creating a visualization model for North Korea’s nuclear facilities as part of these efforts. However, information on North Korea’s nuclear facilities is scarce, and it is not easy to consider additional facilities other than those already known. In addition, in the case of a model that targets only exceptional situations, it is not easy to secure objectivity for model validation, so it is necessary to upgrade to a general-purpose analysis tool that can be applied more generally. The following two examples are proposed as an analysis tool that can be a high degree of analysis. The first case is an Acquisition Path Analysis (APA) utilized to introduce IAEA’s State-Level Approach (SLA). The acquisition path analysis aims to find and evaluate the technically possible pathways to obtain nuclear materials for nuclear weapons or other nuclear explosive development. It can be an acquisition route if it is possible to produce at least 1 Significant Quantity (SQ) of weapongrade nuclear material within five years. The assessment of technologically feasible pathways is based on available information about the country’s past and present nuclear cycle capabilities. The second is the IAEA Physical Model. The IAEA Physical Model was carried out to introduce a comprehensive approach to all information on a country’s nuclear activities. It describes and characterizes the technologies and processes expressed at all levels of the acquisition path, depending on the development objectives. The IAEA Physical Model attempts a multi-tiered acquisition path analysis to identify all known technologies and processes in the nuclear fuel cycle, from raw material production to weapon usable material acquisition. Based on this analysis, the IAEA evaluates the signs of nuclear proliferation in a specific country. Based on the two cases discussed above, we intend to derive the following implications and priorities for extending the existing nuclear cycle model to a more general-purpose for a specific country. First of all, the requirements necessary to evaluate nuclear non-proliferation or verification of denuclearization must be at a level that the international community can recognize. In the stage of actual denuclearization verification, since verification will be conducted through the IAEA, a corresponding level of tools and technology will be required. From this point of view, the following is presented as a prerequisite for adding versatility to the existing physical model: It is necessary to derive all processes related to the nuclear cycle and standardize relevant indicators and data. In order to determine the signs of nuclear activity, detailed information on technologies, materials, by-products, and wastes, which are essential for each process, is required. For denuclearization verification, cumulative information from the past to the time point is required, and a comparative analysis of the operation history information of all facilities and the amount of nuclear material is required. To this end, it is necessary to make it possible to trace the history at every point where it can be determined that nuclear material has been diverted so that missing nuclear material can be found. Based on this, it is expected that it can be possible to evaluate a hypothetical threat state, but it is also expected that it will be easy to verify the model through the evaluation of easily accessible domestic facilities.