Polymer gel implant for soft tissue augment is demanded biological safety properties. This study is designed process and equipment producing for obtain micro bead using the hyaluronic acid water solution. This equipment is composed of cooling pipe, air pump, dispenser and process is consecutive/simple for preservation from environmental contamination. Besides, without difficulty remove the residual agent after crosslink. We evaluate to in vitro cytotoxicity test for verification of hyaluronic acid gel obtained by this equipment and process. This product is "non cytotoxcity" from the result of evaluation cytotoxcity test.

Aloe gel의 동결건조에 농축도가 서로 다른 액상 시료를 사용하였을 때 건조분말의 기능성 변화를 비교분석하였다. Aloe의 많은 기능성 중에서 유효 다당류의 농도, 기능성 작용기에 대한 FT-IR 특성, Jack bean urease 저해 효과, FAC(fat adsorption capacity)를 대상으로 하였다. 농축도가 높은 경우에 유효 다당류의 농도, urease 저해 효과, FAC 모두 상대적으로 크게 나타났다. FT-IR의 분석에서는 농축도가 높은 경우에 glucomannan의 acetyl 기에 대한 spectrum 영역인 1600-1550 cm-1와 1450-1400 cm-1에서 흡광도가 크게 관찰되었다. 결과적으로 Aloe gel의 동결건조 시 전처리과정인 농축 공정에서는 농축도가 높을수록 유효 다당류의 양과 acetyl기 함량의 수준이 크며, 간접적으로 urease 저해 효과에 따른 Helicobacter pylori의 억제 및 FAC의 증가 효과를 보였다.

In this study, we investigated the unit process parameters in spherical kernel preparation. Nearly perfect spherical microspheres were obtained from the 0.6M of U-concentration in the broth solution, and the microstructure of the kernel appeared the good results in the calcining, reducing, and sintering processes. For good sphericity, high density, suitable microstructure, and no-crack final microspheres, the temperature control range in calcination process was , and the microstructure, the pore structure, and the density of kernel could be controlled in this temperature range. Also, the concentration changes of the ageing solution in aging step were not effective factor in the gelation of the liquid droplets, but the temperature change of the ageing solution was very sensitive for the final ADU gel particles

2-dimensional silica-silica Continuous Fiber-reinforced Ceramic.matrix Composites (CFCCs) were fabricated by a sol-gel infilitration method that has a changing processing condition, such as the repetitions of infilitration. In order to investigate the relationship between the processing condition and the mechanical properties of composites, the mechanical properties of specimens were measured by means of a 4-point flexural strength test while the evidence of strength degradation were microstructurally characterized. There seemed to be a minimum density value that existed at which the delamination between the fabrics would not occur. In the case that the density of silica CFCCs exceeded 1.55 g/cm3, the flexural strength also exceeded approximately 18 MPa at least. By applying the Minimum Solid Area (MSA) analysis of the porous structure, the correlation between the relative density and the mechanical properties of composites will be discussed.

Multi-elements doped TiO2 was prepared as a new photocatalyst in order to decrease the band gap of TiO2 by sol-gel process which can provide the large active sites of TiO2. Multi-elements were doped by using a single precursor, tetraethylammonium tetrafluoroborate (TEATFB). By the benefit of large specific surface area of TiO2 prepared by sol-gel process, catalysts showed initial fast removal of dye. The photoactivity showed that the doped catalysts significantly promote the light reactivity than undoped TiO2. The commendable photoactivity of prepared catalysts is predominantly attributable to the doping of anions which may reduce the band gap.

In this report, the structural and optical properties of sol-gel derived MgxZn1-xO thin films upon changes in the composition and annealing temperature were investigated. The Mg2+ content and the annealing temperature were varied in the range of 0≤x≤0.35 and 400˚C≤T≤600˚C, respectively. The films exhibited a hexagonal wurtzite structure of a polycrystalline nature. The optical transmittance exceeded 85% and the optical band gap of the film was tuned as high as 3.84 eV at a value of x = 0.35 (annealed at 400˚C), which was evidently the maximum Mg2+ content for the single-phase polycrystalline MgxZn1-xO thin films prepared in this experiment. The optical band gap and photoluminescence emission were tailored to the higher energy side while maintaining crystallinity without a significant change of the lattice constant.

The structural and physicochemical properties of dried aloe vera gel by DIS (dewatering impregnation soaking) process under optimum conditions were investigated. FT-IR spectra for dried samples of DIS aloes showed the typical patterns of standard aloe polysaccharide, and surface structures by SEM (scanning electron microscopy) were similar to a gel-like structure. In case of physicochemical properties of dried aloe samples by DIS process, solubilities and swelling powers of control (not osmotic treated aloe), DIS (S) and DIS (G), samples treated by osmotic solution of 60% sucrose/0.25% NaCl and 50% glucose/0.5% NaCl, were 48.3-57.3% and 8.3-11.7%, respectively, showing no significant differences among samples, but swelling power of DIS (PEG), sample treated by using 50% polyethylene glycol as an osmotic agent was about 5 times higher that of control. Also, water holding capacities of control, DIS (S) and DIS (G) were similar to each other, but that of DIS (PEG) was about 5 times higher that of control. Oil holding capacities of control and DIS aloes maintained the 50.9-86.4% levels of water holding capacities showing no significant differences among samples. Rehydration ratio of DIS (PEG) aloes were significantly dependent on the temperature of rehydrated solvent (water), and rehydration ratio of not-fileted aloe was about two folds higher than that of fileted aloe.

The early diagnosis of bovine pregnancy is an essential component of successful reproductive planning on farms, because lack of bovine pregnancy over the long term results in reproductive failure and low milk yield‐the latter of which is a special concern on dairy farms. This study was designed to identify early pregnancy‐specific whey proteins in bovine, by comparing milk samples collected from cattle during pregnancy (Days 30 and 50) and from non‐pregnant cattle. In this study, differentially expressed proteins in five pregnant and five non‐pregnant Holstein dairy cattle were investigated and compared, using proteomics analysis. The first dimension was applied to a pH 3.0～10.0 strip, by loading a 2‐mg milk protein sample. After the second‐dimension separation was performed, the gels were stained with colloidal Coomassie brilliant blue. The stained gels were scanned and the images were analyzed, to detect variations in protein spots between non‐pregnant and pregnant cattle milk protein spots, using ImageMaster; this was followed by analysis with MALDI TOF‐MS. Analysis of the 2‐DE gel image resulted in a total of approximately 500～600 protein spots, of which 12 spots were differentially expressed, six spots were up‐regulated, and four spots were downregulated; two spots were identified as pregnancy‐specific proteins. These proteins were identified as lactoferrin, NADH dehydrogenase subunit 2, albumin, serum albumin precursor and transferrin. Our results via 2‐D PAGE analysis revealed composite profiles of several milk proteins related to early bovine pregnancy, implying the possible use of these milk proteins in the early detection of bovine pregnancy.

본 연구에서 졸-겔 방법에 의하여 나노 기공을 가지는 세라믹막을 제조하여 단일 조성의 헬륨과 질소를 가지고 기체투과 실험을 수행하였다. 기공 크기 0.1 μm, 기공율 32%의 평막형 α-Al2O3 지지체를 제조하였으며, 지지체를 담지하여 코팅하는 방법으로 4nm의 기공 크기를 가지는 γ-Al2O3 중간층을 제조하였다. 실리카 졸은 TEOS의 산 촉매 가수분해와 축중합반응을 통하여 합성하였다. 막은 딥코팅과 소결과정을 거쳐 제조되었다. 졸-겔 법에 의해 합성된 세라믹 막을 통한 헬륨, 질소 투과 실험은 기체의 투과 특성을 파악하기 위하여 시행하였다. 질소에 대한 헬륨의 선택도는 100∼160 정도였으며 헬륨의 투과도는 303∼363 K의 온도 범위에서 10 -7 mol/m 2 ⋅s⋅Pa 정도였다.

xTiO2-ySiO2 system photocatalysts were developed by sol-gel method based on the change of production parameters, and their structure of crystallization and the specific surface area were measured. Considering the efficiency of the ethanol and phenol degradation using the catalyst, the conclusions were obtained as follows: By means of X-ray analysis of xTiO2-ySiO2 powder that is obtained from Titanium and Silicon alkoxide by sol-gel process, it is shown that crystal structure of anatase type is a dominating structure and, on the other hand, the structure of rutile also partly exists. The increase of SiO2 contents causes the decrease of the degree of crystallization of the gel, whereas the specific surface area preferentially increases. It is shown that more than 90% of ethanol and phenol are degraded when reaction time is about three and an hours, and the maximum degradation rate of ethanol and phenol is shown in 60TiO2-40SiO2 catalyst.

The ion exchangers supported on silica gel containing primary, secondary, or tertiary amine groups show a behaviour that is weakly acidic, while the quaternary salts are strongly acidic. These properties change according to the hydrophilicities of the modifier functional groups. Ammonium salt derivatives supported on silica gel were prepared from silica modified with 3-Aminopropyltriethoxysiliane and N-3-(Trimethoxysilyl)propylehtylene diamine. The preparation and the ion exchange properties of two systems were discussed. Two systems have different hydrophilicities and contain ammonium chloride derivatives of 3-amminopropyltriethoxysilane and N-3-(triehtoxysilyl)propyl ethylene diamine supported on silica gel, SA+/Cl- and SA+/Cl-, respectively. The high affinity to perchlorate ion presented by the SA+/Cl- through the equilibrium studies of ion exchange led us to its application as an ion selective electrode for the perchlorate ion. The determination of the perchlorate ion in the presence of other anions and in complexes is very difficult. Few analytical methods are available and most of them are indirect. Both materials showed potential use as an ion exchanger; they are thermically stable, achieve equilibrium rapidly in the presence of suitable exchanger ions, and are easily recovered.

BaTiO3 powders were prepared by sol-gel method from different concentration of KOH aqueous solution and Ba/Ti molar ratio. Particle shape, size and crystal structure of prepared BaTiO3 powders were analyzed by SEM, XRD, and FT-IR. As the result of KOH concentration changing, spherical particles were obtained by condition more than 3 M and particle size decreased as concentration increasing. Different appearance showed between dried and sintered powders against changing of Ba/Ti molar ratio. In case of dried powders, the crystallinity decreased as molar ratio increasing. On the other hand, increased as molar ratio increasing in case of sintered powders.

상변환과 졸-겔 반응을 동시에 행하는 새로운 제막법으로 나노크기의 ZrO2 입자가 함유된 비대칭형 PES-ZrO2 복합 막을 제조하였다. PES-ZrO2 복합 막 제조의 최적 제막 조건을 복합 막에의 인 흡착실험을 수행하여 인 흡착량이 최대가 되는 조건으로서 결정하였는바, 최적 제막 조건은 캐스팅 용액에 1 mL의 PES 당 0.15 mL의 Zr(PrO)4 첨가 및 비용매 1 L에 1 mL Zr(PrO)4 당 30 mL의 HNO3 촉매를 첨가했을 때 이었다. 복합 막의 단면 구조, 막성능 및 ZrO2 입자 함유량 변화를 SEM, 순수투과량, TGA, ICP, XRD 및 접촉각 측정을 통해 결정하였는바, 캐스팅 용액에의 Zr(PrO)4 첨가량이 증가할수록 순수 투과량이 증가하며, ZrO2 입자 함유량은 1 mL의 PES 당 0.15 mL의 Zr(PrO)4 첨가했을 때 최대가 되었다. 복합 막의 표면 특성을 친수성으로 개선하기 위하여 인산처리를 하였으며, 인산처리 전후(前後)의 두 종류 PES-ZrO2 복합 막을 대상으로 한 BSA 용액의 dead-end 한외여과 실험을 수행하여 막오염 형성의 억제 정도를 평가한 결과 인산처리 시킨 복합 막의 경우 투과량과 BSA 배제도 모두 약 40% 정도 증가하였는데 이는 복합 막을 인산처리 시킴으로서 막특성이 친수화 되었기 때문이다.