The objective of this study was to compare the feeding effects of imported timothy hay, domestic Italian ryegrass silage (IRGS) and IRG dried by hot-air dry system (IRGHDS) under basic total mixed ration (bTMR) on rumination activity, milk production, and milk composition in lactating dairy cows. Eighteen Holstein dairy cows were divided into three groups: control (bTMR + imported timothy hay), treatment 1 (bTMR + IRGS) and treatment 2 (TMR + IRGHDS) groups. The study was conducted over a total period of 24 days, including a 10 days adaptation period and a 14 days main experimental period. The results indicate body weight was not significantly different between the three groups (p>0.05), and rumination time was significantly higher in the treatment 1 group compared with the control group (p<0.001). Milk fat, protein, and lactose were not significantly different between the three groups (p>0.05), however, somatic cell counts were significantly lower in the treatment 1 group compared with the control group (p<0.001). As a result of the economic feasibility analysis, it is expected that feeding TMR using IRGS and IRGHDS will increase profit by 402.8 won/day and 331.4 won/day per cow compared to imported timothy hay. Therefore, IRGS and IRGHDS can be used as substitutes for imported timothy hay in feeding lactating dairy cows.

Background: In modern society, the use of computers accounts for a large proportion of our daily lives. Although substantial research is being actively conducted on musculoskeletal diseases resulting from computer use, there has been a recent surge in interest in improving the working environment for prevention. Objects: This study aimed to examine the effects of posture correction feedback (PCF) on changes in neck posture and muscle activation during computer typing. Methods: The participants performed a computer typing task in two sessions, each lasting 16 minutes. The participant’s dominant side was photographed and analyzed using ImageJ software to verify neck posture. Surface electromyography (EMG) was used to confirm the participant’s cervical erector spinae (CES) and upper trapezius muscle activities. The EMG signal was analyzed using the percentage of reference voluntary contraction and amplitude probability distribution function (APDF). In the second session, visual and auditory feedback for posture correction was provided if the neck was flexed by more than 15° in the initial position during computer typing. A 20-minute rest period was provided between the two sessions. Results: The neck angle (p = 0.014), CES muscle activity (p = 0.008), and APDF (p = 0.015) showed significant differences depending on the presence of the PCF. Furthermore, significant differences were observed regarding the CES muscle activity (p = 0.001) and APDF (p = 0.002) over time. Conclusion: Our study showed that the feedback system can correct poor posture and reduces unnecessary muscle activation during computer work. The improved neck posture and reduced CES muscle activity observed in this study suggest that neck pain can be prevented. Based on these results, we suggest that the PCF system can be used to prevent neck pain.

This study was performed to investigate the quality characteristics and antioxidant activity of black soybean Sunsik product with functional food ingredients and functional labeling system. We prepared black soybean Sunsik (BS) containing black beans, cereals, and vegetables. Black soybean Sunsik with nondigestible maltodextrin and calcium lactate (BSN) was prepared by adding non-digestible maltodextrin and calcium lactate to the base recipe to apply a functional labeling system. The particle size in BS was 118.00 μm, whereas BSN was 127.00 μm. The respective L, a, and b color values of BS were 73.25, 2.36, and 14.21. The respective L, a, and b values of BSN were 73.21, 2.36, and 14.31. The respective water retention capacities of BS and BSN were 241.67% and 216.33%. No significant difference was observed between BS and BSN in the three physicochemical properties described above. However, the pH of BSN was 5.45, which was significantly lower than that of BS. The total respective phenolic contents of BS and BSN were 1.75 mg GAE/g and 1.61 mg GAE/g, and total respective flavonoid contents of BS and BSN were 6.36 mg RE/g and 5.95 mg RE/g. The antioxidant capacities of BS and BSN were compared via assays of DPPH and ABTS radical scavenging activities, FRAP, and reducing power. The antioxidant activities of BS and BSN increased in a dose-dependant manner. No significant difference between BS and BSN was observed in any measure of antioxidant capacity. These results suggested that the addition of functional food ingredients (non-digestible maltodextrin and calcium lactate) did not affect the quality characteristics and antioxidant activity of black soybean Sunsik.

본 연구에서는 기존의 신호체계에서 발생하는 황색 신호 딜레마 상황에서 운전자의 상태를 파악하고 새로운 신호체계를 제안하고자 한다. 특히, 생체신호 분석을 통해 운전자 중심의 대처모형을 제안한다. 이를 위해 자동차 그래픽 시뮬레이터를 통해 교차로 도로 주행상황을 구현하여 기존의 신호체계와 본 연구에서 제안하는 신호체계에서 운전자의 생리적 반응을 관찰하여 규명하고자 한다. 따라서 대조군(기존 신호체계)과 새로운 황색 신호체계를 실험군(새로운 신호체계)으로 나누어 20대 초보 운전자를 중심으로 실험을 진행하였다. 그 결과, 대조군보다 실험군에서 교감신경의 출현이 우세하였으며 통계적으로 유의차가 인정되었다(p<0.05). 이를 통해 새로운 신호체계가 운전자가 긴장감을 유발하는 것처럼 보이지만 교감신경과 부교감신경의 비율이 6:4로 이상적인 균형으로 해석할 수 있다. 결론적으로, 본 연구에서 제안하는 대처 신호체계를 교통체계에 적용한다면 운전자가 더욱 안정적인 주행이 가능할 것으로 보인다.

Background: Previous robot-mediated gait training has been proven several limitations such as pointless repeated motion training, decreased presence, etc. In this research, adult stroke patients were participated in robot-mediated gait training accompanied with or without virtual reality program. Objectives: Exploring whether the results indicated virtual reality system has contribution to muscle strength and balance ability. Design: A case series research, cross-over trial. Methods: Eleven participants (male 4, female 7) with adults diagnosed as stroke from medical doctor ware engaged. The participants received 2 treatment sessions of identical duration, robot-assisted gait training with virtual reality and robot-assisted gait training with screen-off randomly crossed over include 1-day for each person of wash-out period. The parameter was muscle activity, the researchers assessed sEMG (surface electromyography). Results: The result showed less muscle activities during training in robotassisted gait training with virtual reality circumstances, and these indicated muscles were gluteus medius muscle, vastus medialis muscle, vastus intermedius and vastus lateralis muscle, semimembranosus muscle, gastrocnemius- lateral head, and soleus muscle (P<.05). Conclusion: In this study, we analyzed the outcome of muscle activity for clinical inference of robot-assisted gait training with virtual reality (VR). Less muscle activity was measured in the treatment accompanied by VR, therefore, a more systematic, in-depth and well-founded level of follow-up research is needed.

Background: It is difficult to assess whether community-dwelling frail older adults may remain pre-frail status or improve into a robust state without being directly checked by health care professionals. The health information perceived by older adults is considered to be one of best sources of potential concerns in older adult population. An online measurement system combined with item response theory (IRT) and computer adaptive testing (CAT) methods is likely to become a realistic approach to remotely monitor physical activity status of frail older adults. Objects: This article suggests an approach to provide a precise and efficient means of measuring physical activity levels of community-dwelling frail older adults. Methods: Article reviews were reviewed and summarized. Results: In comparison to the classical test theory (CTT), the IRT method is empirically aimed to focus on the psychometric properties of individual test items in lieu of the test as a whole. These properties allow creating a large item pool that can capture the broad range of physical activity levels. The CAT method administers test items by an algorithm that select items matched to the physical activity levels of the older adults. Conclusion: An online measurement system combined with these two methods would allow adequate physical activity measurement that may be useful to remotely monitor the activity level of community-dwelling frail older adults.

본 연구는 멀티플 에멀젼(W/O/W) 시스템을 이용하여 개발한 자외선차단 제품의 자외선차단성능의 지속성과 보습효과에 관한 연구이다. 자외선차단용 화장품은 장시간의 외출, 등산, 레포츠 활동을 할 때 필수적으로 사용하는 제품으로 높은 자외선차단효과와 지속성이 요구되고 있다. 또한, 소비자들은 감성공학적인 측면에서 끈적이지 않으며, 내수성이 우수한 제품을 선호하고 있다. 친수성 (O/W타입) 자외선차단제품의 경우, 사용감은 우수하나, 땀이나, 물에 쉽게 지워지기 때문에 완벽한 자외선차단효과를 기대할 수 없으며, 내수성이 우수한 친유형 (W/O타입) 제품의 경우, 내수성은 우수하나, 끈적임이 심하고, 보습효과가 낮다. 따라서 본 연구에서는 멀티플에멀젼(W/O/W)시스템의 퍼뮬레이션을 개발하여 친수성크림의 부드럽고 촉촉한 사용감을 부여하고 흡수 후에는 내수성이 우수한 W/O 제형으로 변화하여, 우수한 내수성과 자외선차단효과의 지속성을 가지는 고기능성 다중에멀젼의 자외선차단크림을 개발하는 것이 목적이다. 자외선차단크림에 사용된 성분으로 UV-B를 차단하는 원료 에칠헥실메톡시 신나메이트, 이소아밀-p-메톡시신나메이트, 에틸헥실살리실레이트, 옥토크릴렌을 사용하였으며, UV-A차단제로 부틸메톡시디벤조일메탄과 비스에칠헥실옥시페놀 메톡시페닐트리아진을 사용하였다. O/W형 크림의 자외선차단효과를 나타내는 SPF 수치가 34.1, W/O/W형 크림에서는 SPF 수치가 40.6으로, O/W형 크림보다는 19%정도 자외선 차단효과가 상승하는 것으로 나타났다. 4시간 경과 후의 내수성시험에서는 O/W형 크림의 경우 자외선차단효과가 3.6정도로 30.5이상 하락하였으나, 다중에멀젼 시스템에서는 자외선차단효과가 32.7로, 7.9정도 하락하여 81%의 내수성이 있는 것으로 나타났다. 사용 30분 후의 보습효과는 친수성크림이 우수하였으나, 3시간 이후의 보습력은 멀티플에멀젼에서 더욱 높은 보습효과를 보였다.

This study was designed to determine the antioxidant activity of solvent fractions of broccoli sprouts grown by controlling the growing environment at the plant factory system. Fractionation was achieved with chloroform, n-hexane, ethyl acetate, butanol, water by 70% EtOH extract of the broccoli sprouts. Each solvent fraction was put through TLC and HPLC to separate active components. Higher antioxidant activities were observed for the butanol and ethyl acetate layers. Further evaluation of each of the 5 layers (LH1 to LH5) of the butanol fraction showed that the refined LH3 extract had a high antioxidant effect. Components with similar Rf values from TLC had the same retention times and peaks in the HPLC analysis. It was also determined that the sulforaphane content was high at the chloroform and butanol layers and the sulforaphane was responsible for, the high antioxidant activity. Thus, to use for functional materials, the butanol extract/layer of broccoli sprouts is recommended as the most effective.

The purpose of this study is to implement and develop the integrated Economic Value Added (EVA) and Time-Driven Activity-Based Costing (TDABC) model to seek both improvement of Net Operating Profit Less Adjusted Tax (NOPLAT) and reduction of Capital Charge (CC). Net Operating Profit Less Adjusted Tax (NOPLAT) can be maximized by reducing the indirect cost of an unused resource capacity increased by Cost Capacity Ratio (CCR) of TDABC. On the other hand, Capital Charge (CC) can be minimized by improving the efficiency of Invested Capital (IC) considered by Weighted Average Cost of Capital (WACC) of EVA. In addition, the integrated system of TDABC using Balance Scorecard (BSC) and EVA is developed by linking between the lagging indicators and the three leading indicators. The three leading indicators include customer, internal process and growth and learning perspectives whereas the lagging indicator includes NOPLAT and CC in terms of financial perspective. When the Critical Success Factor (CSF) of BSC is cascading as a cause and an effect relationship, time driver of TDABC and capital driver of EVA can be used efficiently as Key Performance Indicator (KPI) of BSC. For a better understanding of the proposed EVA/TDABC model and BSC/EVA/TDABC model, numerical examples are derived from this paper. From the proposed model, the time driver of TDABC and the capital driver of EVA are known to lessen indirect cost from comprehensive income statement when increasing the efficiency of operating IC from the statement of financial position with unified KPI cascading of aligned BSC CSFs.

최근 서비스 산업이 성장하면서 창업활동이 매우 활성화되고 있다. 창업활동은 경제에 새로운 활력을 불어넣어준다는 측면에서 경제성장에 긍정적인 영향을 미친다고 알려져 있지만 어떤 과정을 통해 경제성장률을 제고시키는지에 대한 연구는 매우 부족한 실정이다. 이에 본 연구에서는 금융시스템의 발전단계에 따라 창업활동이 경제성장에 미치는 영향이 어떻게 달라지는지 분석하였다. 분석대상을 고소득 국가군과 중간소득 국가군으로 구분하여 실증 분석한 결과 창업활동은 모든 분석 국가집단에서 경제성장에 유의한 양(+)의 영향을 미치는 것으로 나타났다. 한편, 금융시스템의 발전단계를 고려한 분석결과에 따르면, 고소득 국가군에서는 창업활동이 시장 중심 금융시스템의 발달과 연계하여 경제성장에 영향을 미치고 있었지만 중간소득 국가군에서는 은행 중심 금융시스템과 상호작용하여 경제성장에 영향을 미치는 것으로 나타났다. 하지만 금융시스템의 발전단계와의 상호작용변수의 추정계수는 유의한 음(-)의 값을 보였다. 이러한 결과는 창업활동이 경제성장에 미치는 긍정적인 효과가 금융시스템의 발전에 의해 오히려 약화된다는 것을 의미한다. 따라서 기존의 금융시스템 외에 창업활동을 지원하는 금융 서비스를 정책적으로 강화하는 것이 매우 중요하다고 여겨진다. 그러나 장기적인 관점에서 정책적으로 직접적인 창업자금을 조달하기보다는 시장을 이용한 자본조달 시스템을 강화하는 한편 창업 실패에 대한 안전장치를 마련하는 등의 추가적인 조치를 취하는 것이 바람직할 것이다.

Recently, self-propagating high-temperature synthesis (SHS), related to metallic and ceramic powder inter- actions, has attracted huge interest from more and more researchers, because it can provide an attractive, energy-efficient approach to the synthesis of simple and complex materials. The adiabatic temperature Tad and apparent activation energy analysis of different thermit systems plays an important role in thermodynamic studies on combustion synthesis. After establishing and verifying a mathematic calculation program for predicting adiabatic temperatures, based on the thermo- dynamic theory of combustion synthesis systems, the adiabatic temperatures of the NiO/Al aluminothermic system dur- ing self-propagating high-temperature synthesis were investigated. The effect of a diluting agent additive fraction on combustion velocity was studied. According to the simulation and experimental results, the apparent activation energy was estimated using the Arrhenius diagram of ln(v/Tad)~1/Tad based on the combustion equation given by Merzhanov et al. When the temperature exceeds the boiling point of aluminum (2,790 K), the apparent activation energy of the NiO/ Al aluminothermic system is 64 ± 14 kJ/mol. In contrast, below 2,790 K, the apparent activation energy is 189 ± 15 kJ/ mol. The process of combustion contributed to the mass-transference of aluminum reactant of the burning compacts. The reliability of the simulation results was experimentally verified.

The present study is designed to explore an anti-tumor activity on crude extracts of Oplopanax elatus. Water extractions of Oplopanax elatus were performed at 100℃(OeE-100). OeE-100 doses up to 62.5 ㎍/㎖ had no cytotoxicity on the tumor cell lines in vitro. In experimental lung metastasis of colon26-M3.1 carcinoma or B16-BL6 melanoma, the prophylactic intravenous (4~100 ㎍/mouse) or oral (2 ㎎/mouse) administration of OeE-100 significantly inhibited tumor metastasis as compared with tumor controls. Peritoneal macrophages stimulated with OeE-100 produced various cytokines such as TNF-α, IL-6 and IL-12. In an analysis of NK-cell activities, i.v. administration of OeE-100 (10~100 ㎍/mouse) significantly augmented the cytotoxicity to YAC-1 tumor cells. Vaccination of mice with boiling-treated tumor cells (BT-vaccine) in combination with OeE-100 (100 ㎍/mouse) showed higher inhibitions in tumor metastasis when compared with the mice of BT-vaccine treatment. In addition, the splenocytes from OeE-100 admixed BT-vaccine immunized mice secreted a higher concentration of Th1 type cytokine such as IFN-γ. These results suggested that the OeE-100 stimulated immune system and was a good candidate adjuvant of anti-tumor immune responses.

개인화의 존중과 평생교육의 개념이 확산되면서 가상학습환경 (Virtual Learning Enviroment)는 모바일 기술의 발달과 함께 빠른속도로 보편화되어가고 있습니다. 실제 교육컨텐츠의 모바일화는 많은 장점을 가지고 있는데，대표적으로 학습자에겐 시간과 장소의 제약을 받지않는다는 점과 교수자 입장에서는 학습자의 관리가 용이하고，수업에 필요한 자료들의 정리，분배，취합등의 행정적인 편리함을 들수 있습니다. 학습자들의 개인상황에 따라，어떤 이들은 실제 강의실에 와서 배우는것보다 Virtual Learning Enviromeant(Vlli)가 더 학습효과를 높일 수도 있는 반면，또 다른 이들은 교수자와의 아이컨텍트가 없고，매개체인 컴퓨터와의 인터렉션만 있을뿐 교수자와의 인터렉션이 없기 때문에 집중력이 떨어져 학습효과가 떨어지거나，아예 학습을 포기하게 되논 현상을 종종 볼 수 있습니다. 이런 단점을 극복하기 위해서는 교수자들의 교육방식의 변화가 요구될수 밖에 없고，이를 지원하기 위한 vlli 디자인도 필요조건이 되어야 합니다. 모바일 러닝은 오래전부터 이뤄졌으나，아직도 vlli가 전통적인 교육방식을 바꾸지는 못하는데는，인지섬리학에 기초한 User In따face(UI) 의 디자인이 맞다고 착각했기 때문입니다. 마치 학습자가 강의실에 가만히 앉아서 수엽을 듣는 것 같은 생각이 툴게 하려고 하고，교수자도 학생들이 앞에 있다는 생각으로 강의를 하기 때문에 모바일 러닝시스템의 디자인과 교수자의 강의컨텐츠에 변화가 거의 없논것입니다. 새로운 시도로， Activity Themy에 기초하여 학습자와 교수자의 상호에 따른 행동들을 이해하고 그 행동들과 매개제와의 인 터랙션들을 레벨별르 분석하여 효율적으로 학습효과를 높이든 교수자의 수업방식의 변화와 그것을 기술적으로 지원할 수 있게 러닝시스템의 디자인도 바뀌어야한다는 취지에서 나온 연구고찰입니다.

This study aims to suggest the basic data for PAPS whose operation is at an early stage to gain ef fectiveness in school scene by analyzing the elementary teachers' recognitions about 5 components of PAPS operation - measurement, assessment, treatment, ap

The purpose of current study was to examine bioaccessibility of antioxidant activity and total phenolic content in each part of water spinach (Ipomoea aquatic Forsk.). In vitro biomimicking system simulated human digestive fluid was employed in order to measure bioavailable anti-oxidative effect and phenolic content. Antioxidant activity and total phenolic content was measured by using the DPPH method and the Folin-Ciocalteu assay, respectively. Stem of water spinach had a higher DPPH free radical scavenging effect (5.43 mg/mL for IC50) than leaf (5.95 mg/mL for IC50), while leaf had a greater level of total phenolic content (287.45 μg GAE/mL) than stem (216.45 μg GAE/mL). Bioaccessible antioxidant capacity and digestive stability of total phenolic content showed a similar pattern to what found in raw materials. Our result also indicated that total phenolic content was not found to be a major marker for prediction of antioxidant activity. It is plausible that other constituents such as vitamin E and C in water spinach could be contributors for antioxidant activities.

본 연구에서는 무구속, 무자각, 무침습적인 패치형 심장활동 모니터링 시스템(HAMS)을 개발하였다. 이 심전도 모듈은 무선 통신을 사용하여 신호를 컴퓨터로 전송 받아 실시간으로 피검자의 심장 활동 상태를 언제 어디서나 장시간 동안 손쉽게 모니터링 측정할 수 있는 이동성을 갖추고 있다. 가슴에 부착이 가능한 패치 타입의 소형 전극을 자체 제작하였고, 측정된 심전도 신호에 대한 신뢰성 검증이 이루어졌다. HRV에 대한 스트레스의 영향을 평가하기 위하여 HAMS을 이용하여 동일한 피험자를 대상으로 HRV 파라미터와 불안, 스트레스 항목에 대한 설문지 평가, 스트레스 호르몬(코티졸)양을 측정하였다. 일상 상태와 스트레스 상황에서의 값들을 비교한 결과, 많은 파라미터에서 유의미한 차이가 나타났다. 또한 피어슨 상관계수로부터 스트레스와 상관성이 높은 파라미터를 검토하였다. 이는 HAMS를 이용하여 자율신경계 기능 평가가 충분히 가능하다는 것을 보여주는 것이다. 이러한 결과로부터 HAMS를 통하여 일상생활에서 심장 이상을 예측할 수 있으며, 건강 모니터링 시스템으로 활용도가 높을 것으로 기대된다.