In apartment buildings in Korea, irregular walls, such as T-, L-, and U-shaped walls, are commonly used. However, in practical design, the geometric irregularities of walls are often neglected when determining the length of the lateral confinement region. Further, although earthquake loads apply from various directions, the lateral confinement region is typically determined for the in-plane direction of the web. Thus, using finite element analysis, this study investigated the structural performance of irregular walls subjected to various loading directions. As the design parameters, wall shape, cross-sectional aspect ratio, and loading direction were addressed. According to the parametric analysis results, as the length of flange in tension increased, the lateral confinement region should be evaluated with consideration of the geometric irregularity. Further, for the L- and U-shaped walls, it is recommended to evaluate the lateral confinement region for various loading directions. Based on these results, a design method to determine the lateral confinement region of irregular walls was suggested.

Spirodela polyrhiza (L.) has been known as greater duckweed or great duckmeat. It is native inhabited in Korea. It is considered as a rich source of primary metabolites including protein, carbohydrates, and fats. Thus, it is considered as an alternative food source for the future. In addition, it has a strong phytoremediation capacity to remove various environmental pollutants, especially inorganic elements and pesticides. With a variety of duckweed’s application, there is an urgent need to develop a cultivation method for a sustainable supply of S. polyrhiza. In this study, an indoor vertical farm has been introduced to optimize duckweed cultivation. Indoor cultivated S. polyrhiza showed about 2-fold higher fresh weight than outdoor cultivated duckweed. Contents of inorganic elements were also significantly reduced in indoor cultivated S. polyrhiza. Especially, lead (Pb), cadmium (Cd), and arsenic (As) were approximately 10-fold decreased in indoor cultivated duckweed. On the other hand, contents of proteins and fats were significantly increased in indoor cultivated S. polyrhiza, while carbohydrates were found more in outdoor cultivated S. polyrhiza. Increasing N content in a homemade nutrition solution also enhanced fresh and dried weights of S. polyrhiza by about 1.8-fold in comparison with other commercial nutrition solutions. Proliferation rate (%) was doubled every 24 hours in this indoor vertical farm, indicating the accomplishment of a sustainable supply for S. polyrhiza. Further studies need to be undertaken to cultivate other duckweeds such as Wolffia arrhiza and Lemna minor using the same indoor farming system.

Oral squamous cell carcinoma (OSCC), which accounts for over 90% of malignancies in the oral cavity, is associated with a poor prognosis, with a 5-year mortality rate reaching of up to 44%. The incidence of OSCC continues to rise annually, and current treatment typically involves a combination of surgical resection, chemotherapy, and radiotherapy. In recent years, there has been growing interest in targeted therapies that exploit molecular markers involved in tumor growth and metastasis. Among these targets, immune checkpoint molecules such as programmed cell death 1 receptor (PD-1) and its ligand, programmed cell death-ligand 1 (PD-L1), have garnered significant attention. Therapies that inhibit these immune checkpoints have been approved for various malignancies, offering new avenues for treatment. Pembrolizumab (Keytruda), a PD-1 immune checkpoint inhibitor, has emerged as a promising therapuetic option for OSCC. However, its clinical response rate in OSCC patients remains below 20%, highlighting the need for combination strategies to enhance therapeutic efficacy. One such approach involves non-thermal plasma (NTP), a novel modality that selectively induces apoptosis in cancer cells. In this study, the authors evaluated the combined effect of Keytruda and NTP in an OSCC xenograft mouse model. The combination therapy demonstrated the tendency of suppressed tumor growth compared to Keytruda monotherapy. This effect was accompanied by increased apoptosis, as indicated by elevated cleaved caspase-3 expression, and reduced proliferation, as shown by decreased Ki-67 expression. Although preliminary, these findings may support the potential clinical application of Keytruda-NTP combined therapy as a novel treatment strategy for OSCC.

Tuned Mass Dampers (TMDs) are widely used to mitigate structural vibrations in buildings and bridges. However, conventional optimization methods often struggle to achieve optimal performance due to the complexity of structural dynamics. This study proposes the NN-L-BFGS-B algorithm, which combines Artificial Neural Networks (ANNs) for global exploration and L-BFGS-B for local exploitation to efficiently optimize TMD parameters. A ten-story shear-building model with a TMD is used for validation. The proposed method achieves the lowest H₂ norm compared to previous studies, demonstrating improved optimization performance. Additionally, NN-L-BFGS-B effectively balances computational efficiency and accuracy, making it adaptable to various engineering optimization problems.

중대재해처벌법은 사업 또는 사업장, 공중이용시설 및 공중교통수단을 운영하 거나 인체에 해로운 원료나 제조물을 취급하면서 안전 ‧ 보건 조치의무를 위반 하여 인명피해를 발생하게 한 사업주, 경영책임자, 공무원 및 법인의 처벌 등 을 규정함으로써 중대재해를 예방하고 시민과 종사자의 생명과 신체를 보호하 는 것을 목적으로 2021. 1. 26. 제정되어 2022. 1. 27.부터 시행에 들어갔다. 제정 당시부터 찬성과 반대의 목소리가 많았다. 사업주나 경영책임자들의 책 임을 강화함으로써 종사자들의 생명과 신체를 보호하고자 하는 측면에서는 필 요한 입법이라는 주장과 너무 과도한 입법이라는 주장이 대립되었다. 그동안 산업 현장에서 근로자들의 보호를 위한 입법이 미비하고 사용자들의 책임을 강화하여야 한다는 주장이 많아 중대재해처벌법이 제정이 되었으나, 중대재해처벌법이 위헌이라는 주장도 많이 제기되었다. 근로자들의 생명과 신체를 보호하고자 하는 입법목적은 정당하다고 할 수 있 다. 그러나 이러한 목적을 위한 입법도 헌법에 위반되어서는 안된다. 특히 사 업주나 경영책임자와 법인을 형사처벌하는 내용의 입법이므로 죄법정주의에 위반되면 안되고 책임과 형벌의 비례원칙에 위반되면 안되며, 기본권 보호를 위한 비례의 원칙 등을 준수하여야 한다. 중대재해처벌법은 근로자의 생명과 신체를 보호하고자 하는 측면에서 필요한 형사처벌 규정을 두고 있으나, 중대재해처벌법을 적용하는데 있어서 불명확하 거나 책임과 형벌간의 비례원칙 등에 위반된다고 판단되는 조문들이 있다. 필 요한 입법이라 하더라도 헌법에 위반되는 법률은 법치주의를 훼손하는 입법이 므로 위헌성을 제거할 필요가 있다. 최근에 중대재해처벌법 일부 조항에 대하 여 법원에서도 위헌법률심판제청을 하였다는 점을 고려하여, 위헌성을 제거하 기 위한 개정 작업이 필요하다고 본다.

Italian ryegrass (Lolium multiflorum L.) is an annual forage crop widely cultivated across the globe for its excellent nutritional value and high productivity. Despite its importance, studies on differentially expressed genes (DEGs) involved in its morphogenesis remain limited. In this study, we employed a high-yielding mutant line developed through radiation mutagenesis to identify candidate genes associated with morphogenesis, focusing on Expansins (EXPs), GRFs (Growth regulating factors), GIFs (GRF-interacting factors), and growth hormone-related genes. RT-qPCR primers were designed, and differential gene expression analysis was performed. Gene expression was assessed in the leaves of seedlings at one to three weeks of age, comparing the control cultivar 'Kowinearly' with the mutant line. Expression patterns fell into four distinct categories: (1) genes consistently exhibiting lower expression in the mutant line across all developmental stages; (2) genes showing persistently low expression in the mutant, while the control displayed a sharp increase at early stages followed by a decline; (3) genes with low expression in the control but a marked early-stage increase in the mutant; and (4) genes with decreasing expression over time in the mutant, contrasting with gradually increasing expression in the control. These expression profiles highlight Actin and GRF6 as Group 1 genes, AXR1 (Auxin-resistant protein 1) and EXPB6 (c) as Group 2 genes, PEVMPP1 (Pyrophosphate-energized vacuolar membrane proton pump 1) as a Group 3 gene, and EF1A (Elongation factor 1-alpha) as a Group 4 gene, all of which are key candidate genes for the development of high-yielding Italian ryegrass cultivars.

무궁화(Hibiscus syriacus L.)는 여름에 크고 화려한 꽃을 피 우는 수종으로 전 세계적으로 주요한 관상수 중 하나로 재배되 고 있다. 분화 재배에 적합한 신품종 육성을 위해 꽃이 크고 개화 기간이 긴 품종 ‘근형’을 모수(母樹)로, 생육이 느리고 가지 정단부에 꽃눈이 집중적으로 형성되는 품종 ‘임진홍’을 수분수 (授粉樹)로 교배하여 단심이 크고 뚜렷한 신품종 ‘라온’을 개발 하였다. 육성과정은 2012년에 양친을 인공교배하여 총 36립의 종자를 수확하여 파종하였고, 2015년에 주요 형질을 평가하여 차대묘 9개체 중 2개체를 1차적으로 선발하였다. 2016년부터 2019년까지 1차선발된 2 개체에 대한 삽목증식과 안정성 평가 를 거쳐 최종적으로 ‘라온’을 선발하였다. ‘라온’은 중앙에 크고 뚜렷한 단심이 있는 백단심계 홑꽃이다. 꽃 직경은 84.2mm로 모수보다 작고, 가지의 길이생장이 연간 평균 13.8cm으로 모수 (연간 평균 33.0cm)보다 느리다. ‘라온’의 개화기간은 68일 정 도이며, 모수에 비해 꽃과 잎이 작고 수고가 낮아져 분화용으로 재배하기에 적합한 것으로 보인다. ‘라온’은 2020년에 제8378 호로 품종보호 등록되었다.

Maize (Zea mays. L) is one of the major sources of green fodder for livestock in Pakistan. Crop management plays a key role in obtaining high yields for green fodder. Fertilizer application, seed rate, and row spacing are critical components of crop management, which can significantly affect crop biomass. To determine the best production technology, a two-year (2021-2023) study was conducted at the research area of National Agricultural Research Center, Islamabad. Plant height, number of leaves, leaf area, green fodder yield per acre, and green fodder yield per hectare were recorded. Various row spacing (15 cm, 30 cm, 45 cm, and 60 cm), fertilizer ratio (N: P = 55:30, 65:40, 75:50, and 85:60), and seed rates (30 kg/ac, 35 kg/ac, 40 kg/ac, and 45 kg/ac) were applied. Results obtained experiments revealed that in both growing seasons, the maximum green fodder yield was obtained when fertilizer N: P ratio was 75:50 (green fodder biomass: 74.61 t/ha and 72.56 t/ha). Similarly, the optimal seed rate was found to be 40 kg/ac, which resulted in the highest green fodder yield (73.41 t/ha and 72.88 t/ha in two seasons). Furthermore, the plant of maize at row spacing of 30 cm was found to generate the maximum green fodder yield (72.39 t/ha and 72.40 t/ha, respectively). Green fodder yield per hectare was found to be positively correlated with plant height, number of leaves, and leaf area. These findings underscore the significance of applying a fertilizer ratio of N: P = 75:50, a seed rate 40 kg/ac, and a row spacing of 45 cm for higher yields of green fodder in maize crop.

This study explored factors affecting variability in second language (L2) learning motivation among Korean university students and how they appraised their L2 learning experience. In this study, 85 undergraduate students majoring in English or English education from three universities in Seoul, South Korea, reflected on their past English learning experience. They drew a motigraph and wrote a retrospective reflection essay covering their English learning that spanned over ten years. Researchers divided participants into two groups: a high variability (HV) group and a low variability (LV) group. Data were analyzed using open, axial, and selective coding. Findings suggest thncontextual factors such as the learning method, atmosphere, and situation were main (de)motivational factors for the HV group. In contrast, the LV group was (de)motivated by intrapersonal factors, including the learning context appraisal. These results imply that visualizing long and short-term goals and positive appraisal of the L2 learning experience can help L2 learners maintain a stable pattern in L2 learning motivation.

Production technology trials for PARC’s new fodder oat cultivar (PARC-Oat) were conducted at the National Agricultural Research Center (NARC) under rain-fed conditions in Islamabad from 2021 to 2023. The effects of different fertilizer doses, planting densities (seed rates), and inter-row spacing on green fodder yield were studied. The experiment comprised four fertilizer doses of nitrogen and phosphorus (N:P) (55:30, 65:40, 75:50, and 85:60 kg/ha), four seed rate densities (30 kg/ac, 35 kg/ac, 40 kg/ac, and 45 kg/ac), and four inter-row spacings (15 cm, 30 cm, 45 cm, and 60 cm). Results based o n k ey p arameters a ffecting t he y ield of PARC-O at—namely plant height (cm), leaf area (cm²), leaves per tiller, number of tillers per plant, and green fodder yield (t/ha)—indicated that the maximum yield of 72.74 t/ha was observed with the fertilizer dose of 75:50 kg/ha (N:P). Similarly, a seed rate of 40 kg/ha produced optimal planting densities, resulting in the highest green fodder yield of 72.85 t/ha, while an inter-row spacing of 30 cm yielded the maximum green fodder yield of 74.30 t/ha. These results suggest that to achieve maximum green fodder biomass of oats, best management practices should include the application of a fertilizer dose of 75:50 (N:P), a seed rate of 40 kg/ha, and an inter-row spacing of 30 cm.

Cool-season grasses are currently widely used in South Korea, but their productivity and quality may decline due to global warming associated with climate change. Warm-season grasses have shown greater adaptability to heat stress and drought conditions, making them potential alternatives for summer pasture establishment in central and southern Korea. This study aimed to compare the growth characteristics, productivity, and forage value of warm-season grasses bermudagrass and crabgrass for pasture establishment in the central region of South Korea. The experiment was conducted from May 2023 to October 2024 at the National Institute of Animal Science, Cheonan, South Korea. Crabgrass exhibited superior initial establishment and faster growth rates, whereas bermudagrass had poor initial growth, placing it at a competitive disadvantage against weeds. However, after the first cutting, bermudagrass successfully established itself and maintained a stable botanical composition. The annual dry matter productivity of crabgrass (8,586 kg/ha in 2023 and 12,013 kg/ha in 2024) was 32.62% and 40.18% higher, respectively, than that of bermudagrass (5,785 kg/ha in 2023 and 8,570 kg/ha in 2024). In forage value, crabgrass tended to show higher feed value at the initial harvest, while bermudagrass showed higher quality at the later harvests. In conclusion, these results suggest that both crabgrass and bermudagrass have potential for pasture establishment, with carbgrass being more suitable for short-term due to its rapid growth and high productivity, and bermudagrass being more appropriate for long-term due to its stable productivity in regions where overwintering in possible.

본 논문은 여씨춘추(呂氏春秋), 회남자(淮南子), 춘추번로(春秋繁露) 세 문헌 을 중심으로 디지털 인문학적 방법을 활용해 분석했다. 주로 텍스트 마이닝 기법을 적용, 세 문헌에 나타난 어휘의 빈도와 그 의미 관계망을 심층적으로 분석하고, 나아 가 각 텍스트의 목차 구조를 면밀히 검토하여 그 사상적 특징을 규명하고자 하였다. 특히 텍스트 마이닝 과정에서 분석의 정밀도를 높이기 위해, Jieba 도구를 활용하여 불용어(不用語)를 세심하게 제거하는 전처리 과정을 거쳤다. 분석 결과, 각 문헌의 핵심 사상과 그 연관성이 뚜렷하게 드러났으며, 이는 디지털 인문학적 접근이 고전 텍스트 연구에 새로운 시각을 제공할 수 있음을 보여준다.

본 연구는 감초(Glycyrrhiza glabra L.)의 미백 화합물인 Glabridin (GB)의 피부 관련 연구의 특성을 검토하여, 새로운 분야의 연구 탐색과 산업적 응용 가치를 판단하기 위해 GB의 생물학적 효능 효 과, 피부 미백과 메커니즘, 안정성 및 제품 활용 관련 문헌을 분석하였다. 구글 학술검색과 PubMed 및 KCI를 통해 피부 미용과 직접적인 특성을 다룬 128편의 문헌을 분석한 결과, GB는 항산화, 항염 등의 효 능으로 피부 미백과 건선, 아토피 등 다양한 피부 증상을 효과적으로 개선한다. 이는 여러 신호 전달 경로 를 조절하는 과정에서 발휘되고 미백은 티로시나아제 활성 억제와 멜라닌 색소의 감소를 통한 색소 침착 개선의 메커니즘을 갖는다. GB의 안정화와 피부 투과도 개선을 위해 리포좀, 캡슐화, 나노입자, 복합체 등 의 기술이 전략적으로 연구됨으로써 고효율의 제품 개발 가능성이 향상되고 있다. GB의 이러한 피부 미용 적 측면에서의 연구 동향을 파악함으로써, 본 연구가 새로운 연구 방향을 제시하고 생체이용률이 증가하는 고효율 화장품 개발에 참고 자료로 활용되기를 기대한다.