As various types of products are produced in a single production system, it is important to determine a scheduling policy that selects one of the different types. In addition, the failure of processes in a line need to be considered due to machine failure, raw material supply and demand, quality issues, and worker absence, etc. Therefore, we studied production systems with various product types, dedicated buffers for each product type, Bernoulli equipment, and WIP-based scheduling or cyclic scheduling. To analyze such system exactly, we introduced a method to analyze the performance such as production rate, WIP level, blocking probability and starvation probability based on Markov chains and derived various characteristics. Especially, assuming that equipment does not need to select the type it just tried, the flow rate is no longer conserved and increasing buffer capacity does not guarantee increase production rate. The performance comparison between WIP-based and cyclic policy is studied as well.

이 논문에서는 부유식 구조체의 계류선에 작용하는 장력을 계산함에 있어서 동적 효과를 고려할 수 있는 준동적 계류선 해석 방법 을 제안하였다. 준동적 계류선 해석 방법은 매 시간 단계에서 계류선의 탄성 현수선 해석해에 기반한 정적 장력을 계산한 후, 준동적 장력 계수를 적용해 속도와 가속도에 따른 항력 및 관성력의 영향을 반영하는 방법이다. 제안하는 방법은 정적 탄성 현수선 해석해를 구할 때 계산 효율성을 높이기 위해 응답면 기법을 도입하고, 수평 및 수직 방향의 동적 계수를 결합하여 준동적 장력 계수를 결정하 는 새로운 방법을 제안하였다. 제안된 모델은 계류된 바지선의 운동 해석을 통해 검증하였으며, 다양한 파 조건에서 동적, 준정적, 준 동적 모델을 비교한 결과, 제안된 준동적 모델은 상대적으로 계류선의 동적 효과가 큰 주파수 대역에서 동적 모델과 유사한 장력 응답 을 도출할 수 있음을 확인하였다.

본 연구의 목적은 재즈 역사에서 인정받고 있는 베이스 연주자 레이 브라운의 즉흥연주 중 투필 베이스 라인을 분석하여 그 특징을 알아보고 이를 통해 , 현대 재즈 연주자들에게 그의 특징인 투 필 베이스 라인을 적용 및 재현하여 재즈의 새로운 시각을 제공하는 데에 있다. 이를 위해 연구방 법으로 재즈 음악에서 가장 기본적인 트리오 구성(피아노, 베이스, 드럼)에서 베이스의 워킹 베이 스 라인 중 레이 브라운의 연주곡 6곡을 선정하여 투 필 베이스 라인의 리듬과 하모니를 심층 분석 하였고 그 결과를 다른 3곡에 적용시켜 레이 브라운 스타일의 예제를 만들었다. 본 연구에서 레이 브라운의 선율적 특징과 화성적 특징, 그리고 리듬적 특징, 테크닉적인 특징을 분석하고 적용하였 고, 선율적 특징은 콜 앤 리스폰스 주법을 사용하였고, 화성적 특징은 가이드 톤 라인을 사용하여 도미넌트 모션을 4번째 박자에 사용하였다. 리듬적 특징으로는 투 필 베이스 라인에서 2분음표로 만 연주하는 것이 아니라 2, 4마디에서는 포비트 워킹 베이스 라인을 연주하여 리듬에 안정감을 더한다는 결과를 도출해 내었다. 이러한 레이 브라운의 고찰이 객관적인 자료로 남아 투 필 베이 스 라인에 대한 기준을 제시해 다른 재즈 베이스 연주자들에게 도움이 됐으면 하고, 솔로 라인이 나 포 비트 워킹 베이스 라인, 솔리스트로서의 발전에 도움이 될 수 있기를 기대하는 바이다.

Oxidative stress caused by reactive oxygen species (ROS) is a key mechanism of skin aging, and the use of antioxidants is an effective strategy to prevent the symptoms associated with ROS-induced skin aging. The components rich in polyphenolic compounds with antioxidative activity were identified by fractionating an aqueous ethanolic extract of Gryllus bimaculatus (AE-GBE) using solvent using hexane, chloroform, ethyl acetate, butanol, and water. Their ability to migrate H2O2-induced oxidative stress in human dermal fibroblasts (HDFs) was then evaluated. The butanol fraction of AE-GBE had the highest polyphenol content and antioxidant effect, followed by the ethyl acetate and water fractions, suggesting that the likely antioxidant components are polar components. Furthermore, the butanol, ethyl acetate, and water fractions effectively reduced intracellular ROS production and DNA damage in HDF cells caused by H2O2. Overall, these findings suggest that the butanol fraction of AE-GBE shows promise as a natural insect-derived antioxidant material, capable of suppressing oxidative stress by showing a stronger antioxidant effect under H2O2 stimulation than the other fractions.

본 논문은 모바일 폰 사진을 활용하여 도시 공간에서 전력선과 건물 사이의 거리를 편리하게 모델링하고 측정하는 방법에 중점을 두고 있으며, 이에 대한 정확성을 평가하였다. 모바일 장 치용 2뷰 지오메트리를 사용한 전력선과 건물의 3D 재구성 방법을 설계하여 어디에서나 즉시 측정할 수 있도록 하였다. 특징점을 사용하여 전력선과 건물 사이의 거리를 계산하고 건물 정 보를 활용하여 게임 가상 공간에 전력선과 전주를 배치할 수 있다. 본 논문에서는 대전시 내 10개의 위치에서 실험을 실시하고, 상업용 시스템과 LiDAR가 있는 경우와 없는 경우를 포함 한 이전 방법과의 성능을 평가하였다. 우리의 방법을 스마트폰에 구현했기 때문에 장점은 휴 대성과 저렴함이다.

This study examined the quality characteristics of 10 different lines of native peppers collected from organic farms in Chungbuk province. The study found a strong correlation between the redness (a*) and ASTA values, which both contribute to the perceived quality of peppers. The highest values were observed in the Iyugsa line. The content of capsaicinoid and beta-carotene also showed a positive correlation, with Chilsungcho having the highest statistically significant value. While the total polyphenol content did not correlate with the other indicators, Chilsungcho again had the highest levels. The Yuwolcho line exhibited the highest ABTS radical scavenging ability, while the Eumseongcho line showed the highest DPPH radical scavenging ability. Taking into account the overall bioactivity quality, Chilsungcho had the highest values in terms of total polyphenol, beta-carotene, capsaicinoid, and redness. It also had the second highest total flavonoid content, ABTS, and DPPH radical scavenging activity, all statistically significant. Therefore, Chilsungcho can be considered an excellent choice when considering physiological activity. Furthermore, this study provides valuable information about the unique characteristics of these 10 native pepper lines, which can assist in selecting the appropriate pepper for food manufacturing and serve as a helpful resource for future research.

Restraints of Branch Lines are used as earthquake-resistant support devices for fire-fighting pipes along with sway brace devices. The central types are aligned and fixed in a straight line with center of the pipe, but the eccentric types are fixed to on side of the pipe, so a bending moment occurs. In this study, three specimens each of central type and eccentric type were installed at an angle of 45° from the vertical and a monotonic compression load of 1340N was applied. All central type samples satisfied 17.8mm of the allowable displacement, but all eccentric type samples failed to meet the target load and buckled. Therefore, when considering the performance of eccentric type restraints, both compressive load and bending moment must be considered. Even through material mechanics calculations, the yield stress of eccentric type - 3/8 inch all threaded steel bolt - exceeds 320Mpa of the allowable stress. A experiment standards need to be established for eccentric type restraints.

Uncoupling protein 1 (UCP1) is a unique mitochondrial membranous protein expressed in brown adipose tissue (BAT) in mammals. While its expression in response to cold temperatures and adipogenic inducers is well-characterized in mammals and human infants, the molecular characterization and expression of UCP1 in fish remain unexplored. To address this gap, we analyzed UCP1 expression in response to adipogenic inducers in a fish cell line, rainbow trout gonadal cells (RTG-2), and compared it with UCP1 expression in three mammalian preadipocytes, 3T3-L1, T37i, and WT1 exposed to the Peroxisome proliferator-activated receptor gamma (PPARγ) agonists, rosiglitazone (Rosi). In mammalian preadipocytes, UCP1 protein was highly expressed by Rosi, with an induction of adipogenesis observed in a time-dependent manner. This suggests that UCP1 plays a significant role in adipogenesis in mammals. However, RTG-2 cells showed no response to adipogenic inducers and exhibited only marginal expressions of UCP1. These results imply that RTG-2 cells may lack crucial responsive mechanisms to adipogenic signals or that the adipogenic response is regulated by other mechanisms. Further studies are needed to confirm these phenomena in fish preadipocytes when an appropriate cell line is established in future research.

Recently, with the increasing global demand for Ganoderma lucidum as a material for functional beverages, varieties with enhanced functionality are needed. As part of this effort, 10 strains were selected from a collection of 160 G. lucidum strains, based on their quantity and fruiting body characteristics. These included four strains collected in Korea, three in Japan, and three of unknown origin. Approximately 44% of the 1,290 hybrid strains were secured. After two rounds of bag cultivation in oak sawdust, three strains (G-20-4, G-20-5, and G-20-7) were ultimately selected for single-timbered cultivation. Among these, G-20-4 demonstrated the earliest harvesting with a large size and a bright cap. Additionally, this strain exhibited the highest levels of total glucan, β-glucan, total triterpenoid, total polyphenol, and total flavonoid content.

Southeast Asia is home to the Straits of Malacca and Singapore, one of the world’s most important sea lines of communication. The closure of the straits to international navigation may adversely affect the well-being of the global economy. On February 11, 2022, the Biden administration announced the new Indo-Pacific strategy, which will continue to deliver on AUKUS. For centuries, the proposed Thai Canal Project has been planned to revolutionize the shipping industry by bypassing the busy waters of the Straits of Malacca and Singapore. If the canal is built under the US Indo-Pacific Strategy, the pre-eminence of the Straits of Malacca and Singapore will not last long. This article analyzes the potential increase of navigation of nuclear-powered submarines through the Straits of Malacca and Singapore and its ensuing environmental implications from a viewpoint of international law. It discusses effects of the proposed canal plan in influencing the shipping industry should this “dream waterway” be constructed.

Protein and peptide candidates are screened to apply therapeutic application as a drug. Ensuring that these candidates are delivered and maximized effectiveness is still challenging and a variety of studies are ongoing. As drug delivery system vehicles, cell-penetrating peptide (CPP) can deliver various kinds of cargo into the cell cytosol. In a previous study, we developed Ara27 CPP, which are a zinc knuckle family protein of Arabidopsis, and confirmed internalization in human dermal fibroblasts and human dental pulp stem cells at low concentration with short time treatment condition without any toxicity. Ara27, an amphipathic CPP, could be modified and utilized in the biomedical field excluding the risk of toxicity. Therefore, we would like to confirm the non-toxic induced penetrating ability of Ara27 in various cell lines. The purpose of this study was to screen the cell internalization ability of Ara27 in various cell lines and to confirm Ara27 as a promising core CPP structure. First, Ara27 was screened to confirm non-toxicity concentration. Then, fluorescence-labeled Ara27 was treated on human normal cell lines, cancer cell lines and animal cell lines to identify the cellular internalization of Ara27. Ara27 was well intracellular localized in all cell lines and the intensity of fluorescence was remarkably increased in time pass manner. These results indicate that Ara27 has the potential as a core structure for applications in various drug delivery systems.

우리는 CFHT에 부착된 OASIS 분광기, MR 1 그리즘으로 관측한 방출선 중, Hβ와 [O III] 5007 방출선을 분 석하여, 제 2형 세이퍼트 은하 Mrk 1의 운동학적 특성을 파악하였다. [O III] 금지선의 가우시안 선 윤곽 분석을 통해 초과하는 청색 이동 성분의 방출 영역이 비대칭적으로 보이는데, (1) 은하 중심부 약 960 pc거리에서 플럭스는 최대를 보이고, (2) 은하 중심부에서 NS 방향으로 ~900 km s−1인 큰 선폭 지역이 있음을 확인하였다. 두 원소의 분광 영상에서 보이는 시선 속도의 특징은 NE 방향에서 접근하는 가스의 흐름이, SW 방향으로 적색 이동, 즉 멀어지는 가스의 흐름 이 나타나 반시계 방향 은하의 회전 경향성을 보여준다. 시선 속도 자료로부터 은하 중심은 우리를 향해 접근하는 먼 지 가스가 가리고 있음을 파악하였다.