생체 적합성이 우수한 히아루론산과 생분해성이 우수한 폴리 락타이드의 이량체를 결합하여 약물 방출 시스템에 적용할 수 있는 생체 재료를 제조하고자 하였다. 냉동 건조법을 이용하여 히아루론산과 락타이드를 가교제 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide (EDC)로 가교시켰다. 생성된 막을 핵자기 공명 분광법으로 분석하여 락타이드 반응도와 EDC 반응도를 결정하였다. 히아루론산에 대한 락타이드 몰비, 가교제 농도가 증가할수록 혹은 가교 온도가 감소할수록, 락타이드 반응도가 증가하였으며 팽윤도는 감소하였다. 서로 다른 락타이드 반응도를 가진 막으로 약물 방출 실험을 수행한 결과 락타이드 반응도가 증가하면 약물 방출 속도가 감소하는 경향을 보였다. 또 친수성이 다른 여러 가지 약물로 약물 방출 실험을 수행한 결과 친수성이 우수한 약물일수록 서서히 방출되었다.

여름철 팽이버섯 병재배시 톱밥배지에서 발생하는 균사생장 억제증상의 원인을 구명하고 그 경감대책을 확립하기 위하여 톱밥배지 배합시 물온도를 24℃(상온수)와 6℃(저온수)로 하고, 배지제조후 살균전 경과시간을 0, 3, 6, 9시간으로 달리하여 팽이버섯의 재배시험을 수행하였다. 배지제조 후 살균전 시간이 경과함에 따라 배지온도가 상승하고, pH는 6.5에서 5.2∼5.6으로 낮아지는 경향이었다. 이때 톱밥배지 내에서 세균밀도가 증가하였으며, 물온도 24℃에서는 6℃보다 6시간 이후의 세균밀도가 1.9∼4.1배 높았다. 톱밥배지에서 분리한 세균과 대치배양시 팽이버섯균의 생장이 억제되었다. 또한 배지제조후 살균전 시간이 경과함에 따라 배지내의 전질소 함량이 감소하였으며 유리당의 함량도 종류에 따라서 증가 또는 감소하였다. 배지배합시 24℃물 처리구는 6℃물 처리구에 비하여 팽이버섯 병재배사에서 균배양기간 및 버섯발생기간이 각각 1∼2일 지연되는 경향이었으며, 자실체 수량도 저온수 처리구에서 안정적이었다. 그리고 9시간 경과한 배지에서는 균사생장이 정지되었다. 배지제조후 경과시간에 따라 팽이버섯 발생기간은 1∼3일이 지연이 되었으며, 자실체수량은 6시간이 경과된 배지에서 7∼12% 감소하는 경향이었다. 본 시험은 여름철 고온기의 팽이버섯 재배시 배지제조에 6℃이하의 저온수를 사용하여 배지내 미생물 증식을 억제시키고, 입병작업을 마치는 즉시 고압살균 함으로써 배지의 성분을 안정화시켜 버섯의 안정생산에 기여할 것으로 기대된다.

This paper focuses on a BOM(Bill of Materials) management problem for a small and medium manufacturing company that produce automobile parts. Automobile part's manufacturers produce various products due to various automobile characteristics such as types,

In order to investigate the effects of magnetized water treated with HI-Scalper153R on body performance and ammonia concentration in feces of broiler chicks, a feeding trial was conducted with a total of 180 broiler chicks. Each treatment had 18 chicks with 5 replications. Chicks during experimental periods, broiler chicks were fed magnetized water and subterranean water, respectively. The results obtained summarized as follows: Body weight gain slightly increased for broiler chicks fed magnetized water compared with control. But, there is no significantly (p=0.36) different among treatments. Feed intake significantly (p=0.046) decreased for broiler chicks fed magnetized water compared with control. Feed efficiency was significantly (p=0.020) improved for broiler chicks fed magnetized water of each periods when compare to the control. Especially, in starter periods, the feed efficiency of magnetized water treatment increased by 10% more than control (1.80 vs 1.69). In feces, average ammonia concentration (ppm) significantly (p=0.004) decreased in the magnetized water treatment compare to control. Especially, the magnetized water treatment decreased by 2.2 times compared to the control in ammonia concentration of feces (83 vs 37ppm).

The copper oxide nano powders were synthesized by levitational gas condensation (LGC) method, and were applied to catalyst to fabricate 3,4-dihydropyrimidin-2-(1H)-one. Processes of adsorption of Biginelli reaction reagents on the copper nanooxide surface were studied by IR-spectroscopy. It was shown that benzaldehyde coordination, acetoacetic ether on the oxide surface is carried out with participation of carbonyl fragments, urea by N-H bonds which affects positively on the reagents reactivity.

In the present study, silver-doped antibacterial hydroxyapatites were successfully prepared by the sol-gel method. For the starting solution, the molar ratio of was set to 0.075:0.045:20:0.135; was added to a ratio of Ag to total cation concentration of . The prepared sol was dried at for 48h and heat-treated at for 2h to obtain particles in the 200-500nm size range. The product from the synthesis of silver-doped hydroxyapatite was investigated through X-ray diffraction experiments and scanning electron microscopy. The product showed high antibacterial properties, with a disinfection ratio of Staphylococcus aureus (ATCC 6538) and Escherichia coli (ATCC 25922) over as calculated from an antimicrobial effects evaluation by the shake flask method.

The with various phases were prepared by simple ex-situ hydrolysis and spark plasma sintering (SPS) process of Al powder. The nano bayerite phase was derived by hydrolysis of commercial powder of Al with micrometer size, whereas the bohemite (AlO(OH)) phase was obtained by hydrolysis of nano Al powder synthesized by pulsed wire evaporation (PWE) method. Compaction as well as dehydration of both nano bayerite and bohemite was carried out simultaneously by SPS method, which is used to fabricate dense powder compacts with a rapid heating rate of per min. under the pressure of 50MPa. After compaction treatment in the temperature ranges from , the bayerite and bohemite phases change into various alumina phases depending on the compaction temperatures. The bayerite shows phase transition of sequences. On the other hand, the bohemite experiences the phase transition from AlO(OH) to It shows AlO(OH) sequences. The compacted at shows a high surface area .

This work is to present a new synthesis of metallic glass (MG)/metallic glass (MG) composites using gas atomization and spark plasma sintering (SPS) processes. The MG powders of (CuA) and (NiA) as atomized consist of fully amorphous phases and present a different thermal behavior; (glass transition temperature) and (crystallization temperature) are 716K and 765K for the Cu base powder, but 836K and 890K for the Ni base ones, respectively. SPS process was used to consolidate the mixture of each amorphous powder, being in weight. The resultant phases were Cu crystalline dispersed NiA matrix composites as well as NiA phase dispersed CuA matrix composites, depending on the SPS temperatures. Effect of the second phases embedded in the MG matrix was discussed on the micro-structure and mechanical properties.

Nanopowders of titanium dioxide incorporating the transition metal element(s) were synthesized by flame synthesis method. Single element among Fe(III), Cr(III), and Zn(II) was doped into the interior of crystal; bimetal doping of Fe and Zn was also made. The characteristics of transition-metal-doped nanopowders in the particle feature, crystallography and electronic structures were determined with various analytical tools. The chemical bond of Fe-O-Zn was confirmed to exist in the bimetal-doped nanopowders incorporating Fe-Zn. The transition element incorporated in the was attributed to affect both Ti 3d orbital and O 2p orbital by NEXAFS measurement. The bimetal-doped nanopowder showed light absorption over more wide wavelength range than the single-doped nanopowders

최근 들어 제조가 발생되는 모든 분야에서 정보의 의미론적 전달방법 및 체계를 정형화하는 작업이 표준화와 더불어 활발히 진행되고 있다. 제조시스템에서 문제가 발생하였을 때 간결하고 정확한 문제 진단에 대한 정보전달은 비용의 절감은 물론 생산성 향상을 위해서도 필수적인 요소이다. 본 연구에서는 제조시스템에서 최적화된 정보전달을 위한 상황이론적 방법론을 제시한다. 본 연구에서 제시하는 방법론의 궁극적인 목적은 실제 제조공정이나 현장에서 발생되는 복잡한 정보의 흐름, 표현, 관리를 효율적으로 할 수 있고 작업자, 관리자, 경영자 모두가 공통적으로 활용할 수 있는 정형화된 틀을 만드는데 있다. 본 연구에서 제시하는 방법론은 제조 현장에서 공정상의 문제점을 분석하고 검사할 수 있는 도구로 활용될 수 있을 것이다.

This paper considers six sigma projects for the PCB industry. This paper is divided into the following four parts. In the first part, the concept and properties of six sigma management are introduced. In the second part, some tools of six sigma project using DMAIC phases are studied for a PCB manufacturing process. In the third part, some tools of six sigma project using DMADOV phases are considered for a PCB research and development process. Finally, some tools of six sigma project for a PCB transaction process are given.

재(再) 제조란 폐기된 제품을 회수하여 신제품과 같은 품질상태로 회복시키는 과정으로, 제품의 폐기로 인하여 발생하는 경제적 손실뿐만 아니라 폐기물의 증가로 인한 환경오염의 예방에도 도움을 준다. 이러한 재 제조의 목표는 보다 많은 부품들을 재사용하는 것으로 기존의 수리와 제조 개념이 결합된 형태로서 제품의 완전 해체, 세척, 검사, 부품수리 및 조정과 교체, 제품의 재조립 등의 일련의 단계를 거치게 되며 이 과정에서 부품의 신뢰도는 매우 중요한 요소로 작용하게 된다. 따라서 이 논문에서는 크게 다음의 두 가지 내용에 대해서 다루게 된다. 첫째, 시스템의 가용도를 모델링하는 방법으로 잘 알려진 마코프 모델을 이용하여 재 제조 시스템의 가용도 분석을 위한 모델을 제시한다. 둘째, 가용도 분석을 통한 부품의 재사용 빈도와 이용시간 평가 등을 통하여 재 제조 시스템의 성능을 평가하기 위한 척도를 제시한다.

This study was conducted to develop a functional cookie with the addition of a sweet pumpkin powder on a cookie shape, that showed high preference level to all age group and that was very easily to store because of low moisture content, by substituting partially a sweet pumpkin powder for reducing content of wheat flour. This study has produced the sensory optimal composite recipe by making iced cookies, respectively, with each 5 level of Sweet pumpkin powder(X1), sugar(X2), butter(X3), by C.C.D(Central Composite Design) and conducting sensory evaluation and instrumental analysis by means of RSM(Response Surface Methodology). Sensory items showed very significant values in color, appearance, flavor, overall quality(p〈0.05), texture(p〈0.01), and instrumental analysis showed significant values in lightness, redness(p〈0.01), yellowness, spread ratio, hardness(p〈0.05). Also sensory optimal ratio of Sweet pumpkin cookie was calculated as sweet pumpkin powder 81.8g, sugar 116.6g, butter 210.7g, and it was revealed that the factors of influencing cookie aptitude were in order of Sweet pumpkin powder, butter, sugar.

The purpose of this study is to identify the best firing condition for Celadon, which is one of the famous traditional pottery to represent Korean culture, by minimizing energy consumption, cutting firing time, shortening the time of processing ceramic making, in order to, save energy as well as to protect the potters' health. Most Korean potter starts their reduction from 950℃ to change kiln atmosphere. However on this study, reduction have started from 950℃ to 1200℃ by increasing 50℃ at a time. Then the results are analyzed to be compared to previous Celadon, in colors, chroma, and brightness. As a results, it is found, that the best temperature for starting reduction is 1100℃, when chroma and brightness values to meet same with previous celadon. Therefore the best condition could be made by starting the reduction on 1100℃ to fire celadon, which would have shorten 2 hours of firing process and, at the same time, it could have saved the energy by 12%.