국내에서 재배하는 주요 핵과류(복숭아, 자두, 매실, 체리)에 발생하는 깍지벌레는 뽕나무깍지벌레(Pseudaulacaspis pentagona), 말채나무공깍지벌레(Lecanium corni), 무화과깍지벌레(Coccus hesperidum), 가루깍지벌레류(Pseudococcus sp.) 4종이 발견되었으나, 뽕나무깍지 벌레는 2017년에 총 113과원 중 103과원(발생과원율 91.2%), 2018년에는 77과원 중 64과원(발생과원율 83.1%) 모든 핵과류에서 가장 많이 발생하여 우점종으로 확인되었다. 2017년도에는 5월 상순부터 부화를 시작하여 암컷성충 1마리가 평균 75.5개(47∼159개)의 알을 낳으며 모든 알이 부화하는데 약 19일이 소요되었으며 5월 20일경에 월동성충의 모든 알이 부화하였다. 그러나, 2018년에는 4월 하순부터 부화를 시작하여 (부화율 72%) 부화유충(1령)으로 이동 후 5월 중순부터 고착유충(2~3령), 6월 중순부터 2세대 성충이 활동하기 시작하였다. 부화유충기(1령)에 약제 살포를 하면 살충율이 100.0%이었으나, 고착유충기(2~3령)에는 살충율은 2.7%에 불과하였다. 부화약충기를 제외한 모든 단계에서 몸체가 밀납깍지로 덮여 있어 약제를 살포하여도 직접 접촉되지 않아 치사율이 낮았다. 따라서 반드시 부화약충기에 약제를 살포하여야 방제효과를 높일 수 있다.

배경/목적: 바터팽대부에서 발생하는 선암종은 드문 질환으로 항암화학요법에 대한 연구가 부족하다. 본 연구에서 진 행성 바터팽대부 선암종 환자에서 XELOX 병합요법의 효능 및 안전성을 분석하고자 한다. 방법: 2006년 10월부터 2014년 1월까지 국립암센터에서 XELOX 병합요법으로 치료한 바터팽대부 선암종 환자 28명 을 대상으로 후향적으로 분석하였다. 모든 환자는 진단 당시 전이성 또는 재발한 바터팽대부 선암종 환자이었다. XELOX 병합요법은 외래에서 3주마다 다음과 같은 프로토콜에 따라 투여되었다. 치료 시작 1-14일에 하루 2회 카페시타빈 750 mg/m2를 경구 투여하고, 1일에 옥살리플라틴 130 mg/m2을 정맥 주사하였다. 결과: 24.6개월(범위 4.8-78개월)의 중앙 추적관찰 기간에서 중앙 무진행 생존 기간은 4.8개월(범위 0.7-18.0개월)이었고, 중앙 생존 기간은 11.9개월(범위 2.0–26.1개월)이었다. 1명의 환자(4%)가 완전 관해를 얻었고, 5명의 환자(18%)는 부분 관 해를 보였다. 무진행 생존 기간와 전체 생존 기간에서 항암화 학요법 반응 여부에 따른 차이는 없었다. 환자에서 가장 흔한 3등급의 이상 반응은 메스꺼움과 구토였다(10.7%). 치료와 관 련된 사망은 관찰되지 않았다. 결론: XELOX 요법은 전이 혹은 재발 바터팽대부 선암종에서 비교적 낮은 독성의 발현과 중등도 효과를 보이는 치료법이다.

We performed a survey for flavivirus infection and distribution of Aedes albopictus that known as Zika and Dengue virus vector using black–light trap and BG-sentinel trap around urban area in Korea. Mosquitoes were collected in 27 cities during March to November (twice a month) year 2016. Total numbers of mosquitoes collected 102,102 including 19 species 8 genera during collecting period. Total 21,467 Ae. albopictus was collected that 20,961(24.3%) by BG-sentinel trap and 506 (3.2%) by Black-light trap in urban area. Trap index(trap/night) of Ae. albopictus was showed highest in Hamyang (TI:992.3) and lowest in Taebaek (TI:0.3) there was only collected by Black-light trap. A total of 894 pools from all collecting Ae. albopictus were performed a Flavivirus detection. Flavivirus was not detected during study period. This study may provide basic information for surveillance of imported diseases (include Zika virus) and vectors in Korea.

The tobacco cutworm, Spodoptera litura(Fabricius), is a major pest of tomato and frequently demands control measures. The timing of insecticide application is a key factor in determining its efficiency, so an experiment was designed to investigate this. Application of insecticide was based on three criteria: (i) the number of trap-caught moths in a Delta-type trap with a commercial sex pheromone lure placed in the center of the target area, soon after plant emergence; (ii) the percentage of plants exhibiting pinhole-type damage (10% or 20%) and (iii) the percentage of plants exhibiting shot hole-type damage (10% or 20%) compared to a check plot without any control measures. We found that the number of trap-caught moths was, compared to the other methods, the best means of deciding on insecticide application in tomato plant to control the tobacco cutworm. Using pheromone traps, we obtained the best performance of the insecticide Shinnago, causing > 90% larval mortality. Without insecticide application, tomato yield reduction due to the tobacco cutworm larva damage was 27%.

혼합 간세포-담관암종은 조직학적 특성이 다양한 원발성 간암의 드문 형태이다. 혼합 간세포-담관암종의 근치적 치료 법은 수술적 절제가 유일하나, 진행성 혼합 간세포-담관암종의 치료에 대해서는 잘 정립되어 있지 않다. 저자들은 진행성 혼합 간세포-담관암종에서 선행항암화학요법을 시행 후 근치적 수술이 가능하였고, 수술 15개월 후까지 재발을 보이지 않은 증례를 보고하는 바이다.

This study aims to reveal how EA affects BAX and NF-kB involved in cell deaths from global ischemia, and to do this, observes the changes of BAX and NF-kB caused by EA application after transient global ischemia. The experimental method is to give rise to global ischemia and apply EA to 27 SD rats with the particulars of being six-week-old, male, around-300 gram-weighing, and adapted to laboratory environment for more than a week, and divide them into three groups, that is, GV20 EA group(n=9), L14 EA group(n=9), no-treatment GI group(n=9), and then observe their changes of BAX and NF-kB at the time lapse of 6 hours, 9 hours and 12 hours after ischemia, using western blotting. The numerical decrease of BAX expression at the time lapse of 9 hours after EA application, though not statistically significant, was observed in GV20 EA group and L14 EA group, and the NF-kB expression appeared statistically significant decrease in GV20 EA group and L14 EA group, but the expression was higher in the group with EA application. Therefore, EA application at the early phase of global ischemia is considered to affect BAX and NF-kB and play a positive role in decreasing apoptosis and cell deaths by inflammation.

Background : Unlike Dioscorea japonica or Dioscore opposita, Dioscore alata is a high-temperature crop mainly cultivated in Africa and subtropical regions. Due to recent climate change, its cultivation area is expanding in Korea. In 2016, the Institute for Bioresource Research clarified optimal harvesting stage to increase its tuber yield and ensure safe storability. Methods and Results : As the seed-tubers for this study, Dioscorea alata tubers were cut into a size of 50 g, disinfected with lime powder, dentated on the seed bed with electrothermal wire installed on March 20th, and then planted on the main field on April 15th. The planting distance was 120 ㎝ in width, where the furrows of 90 ㎝ were cladded with black vinyl, in two rows with a column spacing of 25 ㎝. The amounts of applied fertilizers were 2,000 ㎏ compost, 34 ㎏ N2, 28 ㎏ P2O6, and 28 ㎏ K2O. The compost and P2O5 were used in full, where as N2 and K2O were used as original fertilizer 14 (10 ㎏) and additional fertilizer 20 (18 ㎏), respectively. The crop was harvested in six times from September 20th to November 9th, in an interval of 10 days. While harvesting, the ground fresh weight yield and underground tuber yield were investigated. The underground tuber yield was 836, 1,744 and 2,975 ㎏ low at the early harvests on September 20th, 30th, and October 10th, respectively, while it was 3,622, 3,828, 3,818 ㎏ high on October 20th, 30th, and November 9th, respectively. The ground fresh weight yield remained the same. To clarify tuber storability by harvest time, they were stored at 15℃after harvest, and then healthy and corrupt tubers were studied on March 23th. The corruption ratio by harvest time was highest at 39.1% and 29.3% on October 30th and November 9th, respectively, when frost and low temperature damaged harvest. It was 59.0% and 42.8% at the early harvests on September 20th and 30th, respectively. The corruption ratio was lowest on October 20th and October 10th at 29.3% and 39.1%, respectively. Conclusion : Ford. Dioscore alata cultivation, Korea presents a premature and disadvantageous environment with lower temperature and pre-harvest frost at the time of planting. After raising seeding on an electrically heated hot bed, the optimal harvesting stage should be from planting in the middle of April where temperature rises above 1 5℃ to harvesting in the period October 10th - 20th so as to achieve the maximum tuber yield and high storability.

Background : study of long yam and short yam (Dioscorea. opposita) are cultivated in temperate regions but tropical yam (Dioscorea alata) are mainly grown in Africa and sub-tropical regions cultivated crops. Recent tropical yam cultivation area of Korea increased but lack the proper cultivation techniques to climate warming. This study was conducted to elucidate the effect of the timely harvest on Tropical yam at 2015 in Institute of Bioresources Research, GBARES. Methods and Results : Tuber of tropical yam were cut as 40 g, and dust-coating sterilized with lime. Seedlings were grown in heating wire installed seed bed from 11. March to 16. May. Experimental field were fertilized 2,000 kg compost, 34 kg N2, 28 kg P2O5, and 28 kg K2O. All amount of compost and P2O5 treated as basal fertilizer. N2 and K2O treated 14 and 10 kg of basal fertilizer, and 20 and 18 kg of additional fertilizer, respectively. Tillage, covering black PE film with 60×25 cm spacing holes on 120 cm row were conducted. Emergence days from 6. April to 18 May until 28 days to 36 days but 15. June and 9. June were each 19 and 7 days. Dry weigh in early stage due to seedling date, while seedling date according from 6. April to 18. May had no difference. seedling date was not effective on total number of tuber but number of marketable tuber (over 200 g). Marketable tuber number of seedling date according to 20. April was increased 35~132% as 4,028 number per 10 a. And tuber with 20. April was 13~73 g heavier. Tuber yield and marketable tuber yield of seedling date as affected by 20. April were respectively 2,518 and 1,273 kg per 10 a compared to 6. April and from 4. May to 15. June as 1,743~2,457 kg and 484~1,027 kg. Conclusion : Tropical yam is low temperature in the cultivation of Korea but also adverse environmental conditions. Frost is not mature enough off before harvesting. Yam had significant increased marketable tuber (over 200 g) yield due to seedling in mid-April Requires cultivation technology.

Background : Yam absorbs nutrition and water through water absorptive root generated from head of rhizome. Round-shaped yam (RSY, Dioscorea opposita) and tropical round-shaped yam (TRSY, Dioscorea alata)are more sensitive to drought because of shorter head of rhizome and shallower root compared to long yam or short yam. This study was conducted to elucidate the effect of irrigation on RSY and TRSY yam at 205 in Institute of Bioresources Research, GBARES. Methods and Results : Tuber of RSY and TRSY were cut as 40 g, and dust-coating sterilized with lime. Seedlings were grown in heating wire installed seed bed from 25. March to 16. April. Experimental field were fertilized 2,000 kg compost, 34 kg N2, 28 kg P2O5, and 28 kg K2O. All amount of compost and P2O5 treated as basal fertilizer. N2 and K2O treated 14 and 10 kg of basal fertilizer, and 20 and 18 kg of additional fertilizer, respectively. Tillage, installation of drop-watering tapes, and covering black PE film with 60×25 cm spacing holes on 120 cm row were conducted. 20 L per m2 was irrigated 7 days interval except rainy day from middle of May to late of September. RSY had high emergence rate in early stage due to irrigation, while TRSY had no difference. Irrigation was not effective on total number of tuber but number of marketable tuber (over 200 g). Marketable tuber yield of RSY according to irrigation was increased 89% as 1,147 kg per 10 a. And tuber with irrigation was 73 g heavier. Tuber yield and marketable tuber yield of TRSY as affected by irrigation were respectively 2,611 and 1,715 kg per 10 a compared to control, 1,462 and 428 kg. And irrigated tuber was 66 g heavier. Conclusion : TRSY had more effective on irrigation than RSY. Both of yam had significant increased marketable tuber yield due to irrigation. Therefore RSY and TRSY are necessarily irrigated because of those absorptive characteristics, short head of tuber and shallow root.