Previous researches have revealed that dental panoramic radiographs routinely taken in dental clinics can be useful to diagnose low bone density. The purpose of this study is to investigate the prevalence, awareness and treatment rate of low bone density of females utilizing dental panoramic images. Four-hundred-and-fifteen female patients(mean age 70.4 yrs ± 11.4 yrs) between the age of 50s to 90s, at Chonnam National University Dental Hospital were randomly selected for this study. The panoramic radiographs taken from the patients were reviewed for the purpose of interpreting suspected low bone density(SLBD) on the basis of mandibular cortex index. Awareness and treatment rates of osteoporosis were investigated based on electronic records using the past medical history. As a result, the prevalence rate was 42.17%(175 in 415), the osteoporosis-awareness rate 22.3%(39 in 175), and the treatment rate 87%(34 in 39), showing that the osteoporosis-awareness rate was low, but the treatment rate was relatively high. In conclusion, it can be suggested that osteoporosis-awareness rate by diagnosing SLBD with dental panoramic radiographs be increased to help patients to receive proper treatment.

The medicines for treating osteoporosis currently in use have minor to severe side effects, and can be financially burdensome. Thus, there is a need for prevention and alternative supplement that is relatively inexpensive, and can be easily consumed daily as an alternative dietary therapy. In this study, bone marrow density of the spine and femur of osteoporosis patients were checked before and after consuming complex composed of calcium and magnesium, considered to be the core of bone mineral content. November 2017-November 2021, patients with T-score of less than －2.5 or －1.0 < T-score < －2.5 with history of fractures or recent fractures were enrolled. The data of 60 patients who orally administered Ionized Cal/MagTM Complex were reviewed retrospectively, and it was significantly confirmed that the average value of T-score was up-regulated by 0.5. Additionally, the cumulative dose was observed to have a positive effect, on the improvement of BMD in the 2nd Lumbar and Femur neck. It is expected that better results will be achieved if use of the supplement is continued.

본 연구에서는 방사선 촬영 기법을 사용하여 국내에 서식 하는 무미양서류인 청개구리 (Hyla japonica), 옴개구리 (Glandirana rugosa), 참개구리 (Pelophylax nigromaculatus), 황소개구리 (Lithobates catesbeianus)의 체성분과 골밀도를 분석하였다. 이중 엑스선 촬영 장치 (Dual-energy Xray absorptiometry)를 사용하여 체성분과 골밀도를 측정하 였으며 암수 간 차이와 종 간 차이를 파악하였다. 또한 방사선 촬영 기법을 사용한 신체 상태 평가 방법의 효용성을 확인하기 위해 무미양서류 4종의 먹이자원 가용성을 파악하고 신체상태와의 관계를 확인하였다. 신체를 구성하는 성분인 골, 지방, 제지방 비율과 골밀도는 암수 간 차이가 없었지만 무미양서류 4종 간 차이는 있었다. 골밀도와 먹이자원 가용성은 황소개구리가 가장 높았으며 청개구리가 가장 낮았다. 옴개구리와 참개구리의 먹이자원 가용성은 차이는 없었다. 골밀도와 먹이자원 가용성은 유의미한 상관관계를 가졌으며 먹이 상태를 나타내는 질소 안정동위원소비는 골밀도에 의해서만 변화하는 것을 확인하였다. 기회적 포식자인 무미양서류의 먹이 상태 혹은 자원 가용성이 체성분은 물론 골밀도에 영향을 미칠 수 있다. 개체의 신체 상태를 나타내는 체성분과 골밀도는 무미양서류에서 서식지의 안정성을 평가하는 생태지표로서 사용이 가능할 것으로 보인다.

본 연구는 여성노인을 대상으로 라인댄스와 저항성운동을 적용한 복합운동프로그램이 신체수행능력, 골밀도 및 부갑상선호르몬에 미치는 영향을 구명하기 위하여, 만65세~75세 여성노인을 대상으로 운동군 11명, 대조군 11명으로 분류하여 회당 60분씩 주 2회 라인댄스, 1회 저항성운동을 12주간 실시하였다. 운동 수행강도는 운동자각도(RPE)를 이용하여 ‘가볍다’에서 ‘약간 힘들다’ 정도인 11~14 사이를 유지 하였다. 라인댄스와 저항성운동 전·후에 측정한 자료의 그룹 내 차이 비교를 위해 대응표본 T검정, 그룹 간차이는 운동 전·후의 변화량을 산출하여 독립표본 T검정을 실시하였고, 측정변인들에 대한 그룹 및 시기간 상호작용을 검증하기 위해 이원배치 반복측정 분산분석으로 하였으며, 각 항목별 통계적 유의수준은 .05로 설정하였다. 그 결과, 운동군이 신체수행능력 중 균형(p<.05), 보행속도(p<.01), 의자에서 일어서기(p<.001), SPPB 종합점수(p<.001)가 증가하였으며, 골밀도는 요추(L2~L4)골밀도에서 운동군이 유의하게 증가하였고(p<.05), T-score점수는 운동군이 유의한 증가를 보였으나(p<.01), 대조군은 유의한 차이가 나타나지 않았다. PTH수준은 운동군이 유의하게 감소하였고(p<.05), 대조군은 유의한 차이가 나타나지 않았 다. 이상의 결과 규칙적이고 지속적인 신체활동은 여성노인의 신체수행능력, 골밀도 및 부갑상선 호르몬의 변화에 긍정적인 영향을 미친 것으로 사료된다.

This study was conducted to investigate the dietary and other factors affecting bone mineral density (BMD) in older Korean women. A total of 340 women aged 65 to 74 were recruited from the Kugoksoondam area (Kurye, Goksung, Soonchang and Damyang counties), known as the longevity-belt region in Jeonla province, Korea. They were categorized into two groups according to bone status by T-score : a nonosteoporotic group and an osteoporotic group. Demographic characteristics were collected, as well as information on physical measurements, blood tests for biochemical indicators, health status health-related life style, dietary behavior, favorite food groups, nutrient intake and mini nutrition assessment (MNA). The results are as follows: The mean age of 185 nonosteoporotic women was 69.6 years and that of 155 osteoporotic women was 70.9 years (p<0.001). The mean T-score of the nonosteoporotic group was －1.5 mg/cm3 and that of theosteoporotic group was －3.2 mg/cm3 (p<0.001). Height and body weight in the nonosteoporotic group were significantly higher than in the osteoporotic group (p<0.001, respectively). There was no significant difference in BMI, although the BMI in the nonosteoporotic group was slightly higher. Waist and hip circumferences in the nonosteoporotic group were significantly higher than in the osteoporotic group (p<0.01, respectively), and the mid upper arm and calf circumferences were also significantly higher than in the osteoporotic group (p<0.001, p<0.01, respectively). The 5 m walking ability was significantly superior compared to the osteoporotic group. Serum levels did not show any significant differences between the groups and were within normal range. The serum total protein, albumin and Insulin-like growth factor (IGFs) levels of the nonosteoporotic group were significantly higher than those of the osteoporotic group (p<0.05, p<0.05, p<0.001, respectively). IGF was 104.7 ng/mL for the nonosteoporotic group and 88.1 ng/mL for the osteoporotic group. Physical activity and appetite in the nonosteoporotic group were significantly higher (p<0.01, p<0.05, respectively). The favorite food groups of the nonosteoporotic group comprised more meats and fish than those of the osteoporotic group (p<0.05, respectively). Nutrient intake was not significantly different, with the exception of niacin intake (p<0.05), but the nutrient intake of the nonosteoporotic group was slightly higher than that of the osteoporotic group. The niacin intake of the nonosteoporotic group and the osteoporotic group were 11.4 mgNE and 10.0 mgNE, corresponding to 103.6% and 90.9% of the Korean EAR, respectively. The MNA score of the nonosteoporotic group was significantly more favorable than for the osteoporotic group. In conclusion, it is necessary to maintain adequate body weight and muscle mass. Habitual physical activity may have a beneficial effect on BMD for older women. Dietary factors, such as meat and fish, higher intake of niacin rich foods and nutrient status for older women also appear to have favorable effects on bone mineral density.

The objective of this research was to investigate the effect of Taekwondo training for 16 weeks on obese elementary school students’ growth hormone and bone mineral density(BMD). The study was conducted on male obese elementary school students who reside in D metropolitan city and have body mass index (BMI) higher than 25%. The whole subject group had no particular diseases and did not regularly exercise more than twice a week. Based on basal movement, low section, Taekwondo gym and form pattern, the Taekwondo train program was composed of total 16 weeks; 4 weeks of introductory phase, 4 weeks of maintenance phase and 4 weeks of improvement phase one and two, respectively. BMD was analyzed using Dual-energy X-ray absorptiometry standard protocol. As a result, growth hormone was not significantly difference in group and exericse effects. In BMD, there was a significant difference between the two groups in BMD lumber spine(LS). In BMD-femur, there was a significant difference in the group (p<0.01) and time (p<0.05). In body composition, there was no statistically significant difference between body mass, body mass index, body fat mass and muscle volume. In conclusion, since 16 weeks of Taekwondo training had a positive effect on elementary students’ metabolic syndrome index, BMD and postural balance. We can deduce that elementary students need constant physical activity for their growth, physical development and physical health.

The purpose of this study was to investigate the effect of combined exercise training during 12weeks on physical fitness, body composition and bone mineral density in university students. Nineteen male university students who were enrolled of 1st grade at department of physical education in Korea National University of Education were participated in this experiment. Subjects were performed combined exercise training - running, physical training using plyometrics and resistance training - of 5days per week, 70min per 1 time, during 12weeks. The measurement items were health related fitness(muscle strength, muscular endurance, cardiovascular endurance, flexibility), motor skill fitness(power, balance), body composition(% body fat, muscle mass) and bone mineral density(T-score). On the basis of the results analyzed in this study and consideration of many pre studies related it, the result were as follows. First, data analysis of 12 week combined exercise training on health related fitness, post level was revealed more significant increase than pre level at muscle strength(p<.05), muscular endurance(p<.05), cardiovascular endurance(p<.001) and flexibility(p<.05). Second, data analysis of 12 week combined exercise training on motor skill fitness, It was not revealed significant differences between the pre and the post level of the power and balance). Third, data analysis of 12 week combined exercise training on body composition, post level revealed more significant improvement than pre level at muscle mass(p<.05), but It was not revealed significant differences between the pre and the post level of the % body fat. Fourth, data analysis of 12 week combined exercise training on bone mineral density, post level revealed more significant improvement than pre level at T-score(p<.05). In conclusion, It was revealed that 12 week combined exercise training increased physical fitness, and improved body composition and bone mineral density. I hope that more studies will be followed on physical fitness, body composition and bone mineral density on various exercise types, exercise intensity, time and frequency in university students in the future.

무용수는 공연에 대한 스트레스, 식이 조절, 근골격계 손상 등으로 신체조성의 수준이나 골밀 도에 문제가 있는 것으로 알려지고 있다. 이러한 문제로 인하여 한국무용수가 가지고 있는 신체 조성과 골밀도의 특성을 평가하여 건강상태를 파악하고 그에 따른 관리가 이루어질 필요가 있 다. 따라서, 본 연구는 dual-energy X-ray absorptiometry(DEXA)를 이용하여 한국무용 전공 여대생 10명과 일반 여대생 10명의 신체조성과 골밀도를 비교분석하는데 그 목적이 있다. 신체조성은 측정된 DEXA의 결과에서 body mass index(BMI), 체지방률, 근육량, 제지방량을 사용하였으며 골 밀도는 팔, 다리, 척추, 골반 부위의 골밀도 값을 사용하였다. 연구결과 두 집단 간의 BMI(p=.313), 체지방률(p=.060), 근육량(p=.264), 제지방량(p=.272)의 신 체조성은 통계적으로 유의한 차이가 없었으며, 팔(p=.055), 다리(p=.105), 척추(p=.276), 골반 (p=.126) 부위의 골밀도 또한 통계적으로 유의한 차이가 없었다. 결론적으로 한국무용 전공 여대 생과 일반 여대생의 신체조성 및 골밀도의 차이는 없었다. 이러한 연구결과는 한국무용수에게 한국무용과 식이 섭취 경향이 골밀도와 신체조성을 부정적으로 변화시키지 않았으며 오히려 긍 정적인 영향을 준 가능성이 시사되었다.

본 연구는 안전하면서 효율적으로 비만을 개선시키는데 도움이 될 수 있는 식품소재로 목이버섯을 선정하여 복부비만이 있는 중년 여성의 골밀도 및 혈청지질농도에 미치는 영향에 대하여 알아보고자 하였다. 30～50대의 복부비만 여성 30명에게 4주 동안 대조군은 목이버섯을 섭취시키지 않았고, 실험군은 목이버섯을 식사와 함께 섭취하도록 하였다. 실험 전 후 골밀도(T-score, Z-score), 총 콜레스테롤, HDL-콜레스테롤, LDL-콜레스테롤, 중성지방을 측정하였다. 연구결과, 목이버섯 섭취군과 대조군 간에 T-score와 Z-score는 유의한 차이를 보이지 않았지만, 목이버섯 섭취군의 혈청 총 콜레스테롤, LDL-콜레스테롤 및 중성지방 수준이 대조군에 비해 유의하게 소되었다.

The aim of this study was to investigate the correlation among bone mineral density(BMD), body composition and body circumference on 20's college women in Hwaseong. A total of 86 subjects were measured with BMD and body composition and body circumference. To evaluate the correlation between BMD and body composition, bone density and body weight, body mass index(BMI), lean body mass, muscle mass, fat mass and body fat mass were compared. The results of this study, weight was considered the strong correlation with BMD than the height and BMI seems to be greater significance rather than the lumbar spine and femur BMD. In addition, the relationship between body composition and BMD, lean body mass, muscle mass, body fat mass were the most relevant factors and BMD. The relationship between BMD and body circumference that have been difficult because of not enough previous studies but somewhat the study showed that association.

The purpose of this study was to investigate the effect and correlation of anthropometric data, eating behaviors, and nutrient intake on the bone mineral density(BMD) of female college students. 349 female college students were surveyed and their age, height, and weight were an average of 20.5 years, 163.2 ㎝ and 54.0 ㎏, respectively. Their average BMI was 20.2, with 66% falling in the normal range, 21.8% classified as underweight, 8.0% as overweight, and obese individuals comprised 3.4% of the sample by BMI classification. Calcaneal BMD was measured and the average T-score was 0.117. The results of BMD measurements were normal in 268 people(76.8%), osteopenia was found in 71 individuals(20.3%), and osteoporosis in 10(2.9%), respectively. There was a significant difference in bone mineral density according to height(p<0.05) and BMI (p<0.01). There were significant differences between BMD and eating behavior, regularity of eating behaviors(p<0.05), instant food intake(p<0.05), eating out(p<0.05) and nutritional supplement intake(p<0.05). In addition, normal the group with normal BMD had a more desirable eating behavior compared to the osteopenia and osteoporosis afflicted groups. BMD had a significant difference according to the nutrient intake of calcium(p<0.05), vitamin A(p<0.05), and vitamin C(p<0.05). In conclusion, BMD showed a good correlation with height(p<0.01), BMI(p<0.01), body composition including total body water(p<0.05), FFM(p<0.05), body protein(p<0.05) and intake of calcium(p<0.05), iron(p<0.05), vitamin A(p<0.05), and vitamin C(p<0.05). Therefore, an education plan and training on balanced diets proper body weight control, and desirable eating behaviors for female college students will be needed.

The purpose of this study is to examine the changes in bone mineral density in long-stay patients of a geriatric hospital in relation to physical therapy, thereby providing basic data for preventing the onset or deterioration of osteoporosis in inpatients of geriatric hospitals or relevant facilities. The subjects of this study were 133 elderly patients who had been in H geriatric hospital in Yongin-si for more than four years. Their bone mineral density T-scores at admission and those after four years were measured to compare and analyze the changes in bone mineral density in relation to physical therapy. According to the results, the decrease in T-score for the group without physical therapy was greater by .40 than that for the group with physical therapy, indicating a statistically significant difference between the two groups(p<.01). Accordingly, physical therapy proved to be effective in preventing bone mineral density loss and maintaining the current density.

The purpose of present study was to analyze mineral contents in various tissues and investigate theirs relation with bone mineral density (BMD) in rats. Fifteen Sprague-Dawley rats were fed standard diet for 4 weeks. Body weight gain, feed intake, and feed efficiency ratio were 41.00 g/week, 171.15 g/week, and 0.24 respectively. Among 12 minerals in serum, Ca is the highest with 6.86 mg/dl. Serum Mg, Se, and Cu were 2.52 mg/dl, 0.23 mg/dl and 0.22 mg/dl respectively. Mg contents in liver, spleen, and kidney were 246.36 μg/g, 105.01 μg/g, and 273.38 μg/g respectively. Tibia contents of Ca, Mg, Zn, Fe and V were 194.91 mg/g, 23.10 mg/g, 0.60 mg/g, 0.35 mg/g and 0.14 mg/g respectively. BMDs of right tibia and spine were 122.04 mg/cm2 and 153.61 mg/cm2. There were significantly positive correlations between tibia BMD and Se (p<0.05), tibia BMD and V (p<0.01), spinal BMD and V(p<0.05), respectively. It's expected that these results are used as a reference data in following study to elucidate physiological function of minerals.

This study was conducted in order to investigate and compare anthropometric measurements, bone density, nutrient intake, blood composition and food habits between non-smoking, non-alcohol drinking and smoking, alcohol drinking male university students in Seoul, South Korea. The data for food habits and health-related behaviors were obtained by selfadministered questionnaires. The BQIs of the subjects were measured by Quantitative Ultrasound (QUS). The subjects were divided into two groups: NSND (non-smoking and non-alcohol drinking, n=62) group and General (smoking and alcohol drinking, n=160) group. The results were analyzed using the SPSS program and were as follows: The average heights, weights, and BMIs of the two groups were 173.3 cm, 66.5 kg and 22.1 and 173.4 cm, 68.7 kg and 22.9, respectively. There were no differences between the groups regarding height, weight or BMI. SBP and DBP, however, were significantly higher in the general group than in the NSND group (p〈0.01). The BQIs, Z-scores and T-scores of the two groups were 99.83, -0.23, and -0.31 and 98.24, -0.27 and -0.39, respectively, producing no significant differences between the two groups. The percentages for normal bone status, osteopenia and osteoporosis were 83.88%, 16.12% and 0.0% and 74.37%, 25.62% and 0.01%, respectively. Mean intakes of animal protein (p〈0.05), animal fat (p〈0.05), fiber (p〈0.05), animal Ca(p〈0.05), animal Fe (p〈0.001), Zn(p〈0.05), vitamin B1 (p〈0.05) and niacin (p〈0.05) were significantly different between the two groups, and mean serum levels of SGOT (p〈0.01), SGPT (p〈0.001), γ-GTP (p〈0.001), triglycerides (p〈0.01), total cholesterol (p〈0.05) and hematocrit (p〈0.05) were also significantly different between the two groups. Overall, there were no differences in meal regularity, frequency of snacking, reasons for overeating, exercise and defecation between the groups. However, favorite foods (p〈0.05) and night-time meals (p〈0.05) were significantly different. In conclusion, the health status of the NSND group was superior compared to the general group. Thus, students who smoke and alcohol drink should receive a practical and systematically-organized education regarding the increased health benefits of quitting smoking and alcohol drinking.

Hemiplegia-induced immobilizatoin and reduction of mechanical loading in chronic stroke limbs are common cause of disuse osteoporosis. The purpose of this study was to investigate the effects of asymmetrical weight bearing on the loss of bone mineral in the individual with chronic stroke. Sixteen hemiplegic patients with strokes were evaluated. The measurements of bone mineral density (BMD) were evaluated with the quantitative ultrasound system on the calcaneus region of the paretic and non-paretic side. Plantar pressure was measured using the Mat-Scan system. The paretic side showed significantly smaller values in the T-score of BMD, and peak value of plantar pressure, which included forefoot, midfoot, and hindfoot, than the non-paretic side (p<.05). Results from the pearson correlation analysis showed statistically significant correlation between the BMD difference and the peak-pressure difference of midfoot pressure (p<.05). This finding indicated that BMD loss depended on decrease of body weight born on the paretic leg.

Effects of Vegemil® containing soybean proteins and isoflavones on the growth and bone density of broiler chickens were investigated. One-week-old male and female Arbor Acres broiler chickens were fed on Vegemil® A containing 3% soybean proteins and 162 ppm isoflavones, instead of water, for 30 days and their growth indices (body weight, leg weight and femur length) and bone density were analyzed. The body weight gains in male and female chickens were increased by 15.6% and 31.7%, respectively, following feeding Vegemil® A compared to normal water. Vegemil® A increased leg weight as well as femur length of females by 22.9% and 15.0%, respectively. In addition, Vegemil® A feeding enhanced femoral bone density by 21.3% in comparison with water feeding. Therefore, it is suggested that Vegemil® A not only facilitates body growth, but also strengthens bone density of normal chickens, and that it could be a promising candidate for the improvement of infant growth and for the prevention of menopausal osteoporosis.

This study was conducted to investigate bone density and food behavior of middle-aged (〈65-years-of-age) and oldaged women (≥65-years-of-age) in the Seoul area of Korea. Average height and weight, body mass index, body fat percentage, and waist-hip ration (WHR) of the middle-aged participants were 158.0 cm, 58.4 kg, 23.3, 29.7%, and 0.88. Corresponding measurements for old-aged participants were 152.6 cm, 56.3 kg, 24.1, 33.1%, and 0.93. T- and Z-scores for middle-aged women were -1.20 and -0.21, and those of old-aged women were -2.02 and -0.49. Osteopenia and osteoporosis percentage of middle- and old-aged women were 41.2% and 14.7%, and 45.2% and 37.1%, respectively. Significant differences were evident concerning between-meal, overeating, exercise, and nutritional supplementation among the two groups. Middle-aged women displayed a positive relationships between bone density and the parameters of height (p〈0.05), weight (p〈0.05), exercise (p〈0.05), consumption of soybean and soybean-processed food (p〈0.05), and negative relationships between bone density and the parameters of WHR (p〈0.001), consumption of meat and meatprocessed food (p〈0.05), and tea drinking (p〈0.05). In old-aged women group, positive relationships were evident for bone density and the parameters of height (p〈0.05), weight (p〈0.05), exercise (p〈0.05), nutritional supplementation (p〈0.05), and consumption of soybean and soybean-processed food (p〈0.05). The results reveal a link between healthy bones and desirable food behavior, indicating the importance of a practical and systematically organized food behavior education program for middle- and old-aged Korean women.

The principal objective of this study was to assess the effects of soy isoflavone supplementation on bone mineral density in 36 female college students with osteopenia for 12 weeks. The subjects were divided into three groups on the basis of bone mineral density. The experimental groups were provided supplements of either 80 mg of isoflavone (Iso-80) or 40 mg of isoflavone (Iso-40). To the placebo group, 40 mg of powdered glutinous rice was administered. It was determined that many subjects with osteopenia evidenced lower levels of activity as compared to the control group. Isoflavone supplementation was more effective in controlling total cholesterol and LDL-cholesterol than was observed in the placebo group. We noted no significant differences in serum osteocalcin concentration between Iso-40 and the placebo group, but significant differences in osteocalcin concentration were detected between Iso-80 and the placebo group. Bone quality indices (BQI) were correlated positively with mineral content, lean body mass, muscular mass, and blood components including albumin, Ca, Mg, ALPase, and osteocalcin. Both Iso-40 and Iso-80 supplementation for 12 weeks significantly increased protein and mineral content in the body. As lower intakes of Ca and folate were noted in the subjects, emphasis should be given to adequate intakes of these nutrients in the subjects. In conclusion, 12 week isoflavone supplementation in young females with osteopenia exerted positive effects on bone mineral density and bone turnover markers.

The principal objective of this study was to assess the bone density and processed food intake behavior of middle-aged and elderly women in the Seoul area. The subjects were assigned to one of the following groups on the basis of BMI: namely, the underweight, normal, and overweight groups. The results are summarized as follows: The average BMI and systolic blood pressure of the three groups were 19.0, 127.3 mmHg; 22.4, 132.8 mmHg; and 26.8, 136.1 mmHg respectively. The BQI and T-scores of the three groups were as follows: 56.6, -2.50; 62.3, -2.22; 66.0, -2.03 respectively. The bone status of the three groups, in terms of the percentage of normal and osteoporosis, were 9.5%, 52.4%; 8.3% 33.0%; and 8.8%, 23.6% respectively. We noted no significant differences in processed food intake (frozen, cold and can processed food, instant and convenience store food, basic side dishes) behavior among the three groups. However, we recorded a negative value between processed food intake and bone density (BQI, T-score, %young adult, Z-score, %age-matched) generally. In particular, ramyeon (r=-0.1574, p<0.05) and cup-ramyeon (r=-0.1996, p<0.05) intake were significantly associated with the T-scores of bone density levels. The results of this study revealed that processed food intake was not generally desirable for healthy bone. Thus, practically and systematically organized education regarding a good and healthy dietary life is highly recommended.

This study was conducted to investigate the preventing effects of OPB (Rehmannia glutinosa Libosch and Eleutherococcus senticosus Max extracts) and combined OPB/Calcium therapy on bone loss in ovariectomized rats. Sixty Sprague Dawley rats of 12-week-old were divided into eight groups: OVX (ovariectomized), OPBL (OPB 50 mg/kg), OPBM (OPB100 mg/kg), OPBH (OPB 200 mg/kg), OPBL/CAL(OPBL+CAL), OPBM/CAL (OPBM+CAL), OPBH/CAL (OPBH+CAL) and CAL (Calcium citrate 88.33 mg/kg+1, 25-dihydroxy-vitamin D₃33.33 IU/kg). Bone mineral density (BMD), bone mineral content (BMC), bone strength indices and cortical thickness were analyzed by peripheral quantitative computerized tomography (pQCT). pQCT scanning showed that OVX induced a significant decrease in trabecular bone mineral density and bone mineral content in the proximal tibia (-36.4 ±24%, -21.8±12.7%).These decreases were significantly prevented by the administration of OPBM and OPBM/CAL. Cortical BMD and BMC of tibia were slightly enhanced by OPB and OPB/CAL. However there was no significant difference between OVX and OPB, OPB/CAL treated group. Bone strength indices and cortical thickness were not significantly different. Our results suggest that OPB and combined OPB/Calcium therapy are effective in preventing the development of bone loss induced by ovariectomy in rats.