The study aim was to develop and test the effects of integrated simulation pertaining to patients with schizophrenia using a hypertensive crisis module for nursing students. Methods: This pilot study with seven undergraduate nursing students used a single group, pre-post test design. Integrated simulation pertaining to patients with schizophrenia using a hypertensive crisis module was developed based on the ADDIE model (i.e., Analysis, Design, Development, Implementation, and Evaluation), expert meetings with subject professors, a literature review, a preliminary survey, and focus group interviews. Data were collected and measured for general characteristics of the study participants, critical thinking disposition, problem-solving, clinical judgment, self-efficacy, simulation design, and simulation effectiveness. Qualitative contents were analyzed through focus group interviews. Results: No statistically significant differences were found in class design, critical thinking disposition, problem-solving, clinical judgment, and self-efficacy after applying the integrated simulation module. Based on the data obtained from the focus group interviews of study participants, the following four categories were established: “Integrating knowledge and applying it to practice,” “Nursing in unexpected situations,” “Challenged to be an expert,” and “Ensuring receptive and psychological safety in simulation practice.” Conclusion: An integrated simulation module was developed to integrate the nursing problems associated with individual subjects beyond the scope of one subject, and the effect was verified by applying it

본 연구는 장애인 복지관을 이용하는 지체장애인 및 뇌병변장애인 중 고혈압 환자를 대상으로 복지관 간호사와 간호학생 자원봉사자를 통해 제공된 8주 전화상담 고혈압 자가관리 프로그램의 효과를 파악하는데 목적이 있다. 비동등성 대조군 전후 유사실험설계 연구로, 2019년 12월부터 2020년 5월까지 사전, 사후 조사를 완료한 대조군 28명, 실험군 29명의 자료를 SPSS 프로그램을 이용하여 분석하였다. 주요 연구결과로, 프로그램 적용 후 실험군이 대조군에 비해 고혈압 관련 지식, 건강신념 중 심각성과 민감성, 삶의 질 EQ-VAS에서 통계적으로 유의한 차이를 나타나며 높아진 것으로 나타났다. 따라서 장기적인 건강관리가 필수적인 장애인 고혈압 환자를 대상으로 다양한 자가관리 프로그램을 적용하여 관련 지식, 건강신념 및 삶의 질 등을 높이는 노력이 계속적으로 필요할 것이다.

부신에서 기원하는 종양 중 갈색세포종은 일반적으로 고형 병변으로 발현되지만, 드물게 낭성 병변으로 발견되는 경우도 있다 . 고혈압과 동반된 부신의 낭성병변에 대해서 갈색세포종을 감별 진단으로 포함시킬 필요가 있으며, 이를 간과할 경우 다발성 장기 부전을 동반하는 고혈압 위기를 초래할 수 있다. 수술 전후에 있어 적절한 조치가 고혈압성 위기를 예방하는 데 있어 중요하다. 저자들은 부신 낭성 부신 병변에 대한 초음파 내시경 유도하 조직 검사로 인하여 유발된 고혈압성 위기가 발생한 갈색세포종 증례를 경험하여 문헌고찰과 함께 보고하는 바이다.

본 연구는 40-60세 남성들 119명을 대상으로 혈압과 체위지수 및 생화학적 지수와의 관련성을 조사 ․ 분석하였다. 평균 혈압은 정상혈압군 104.5 ± 5.9/67.3 ± 5.0 mmHg, 전단계고혈압군 125.2 ± 5.1/77.5 ± 7.1 mmHg, 고혈압군 143.5 ± 8.9/90.2 ± 7.3 mmHg로 나타났다. 체질량지수 및 허리-엉덩이둘레비는 고혈압군이 정상혈압군 및 전단계고혈압군보다 높았다. 혈색소와 혈청 알부민, 포도당, 알라닌트랜스아미나제, 알도스테론 농도는 고혈압군이 정상혈압군 및 전단계고혈압군보다 높았다. 혈청 총콜레스테롤, LDL-콜레스테롤, 아포지단백 B 농도 및 동맥경화지수는 전단계고혈압군 및 고혈압군이 정상혈압군보다 높았다. 혈압이 높은 군일수록 혈청 중성지질 농도는 높은 반면 혈장 아스코르브산의 농도는 낮았다. 전단계고혈압군인 경우에 체질량지수는 아포지단백 A1 및 아스코르브산 농도와 음의 상관성을 나타내었고, 고혈압군인 경우에 체질량지수는 중성지질 농도와, 허리-엉덩이둘레비는 총 콜레스테롤 및 LDL-콜레스테롤 농도와 각각 양의 상관성을 나타내었다. 아스코르브산 농도는 정상혈압군과 고혈압군에서 HDL-콜레스테롤 및 아포지단백 A1 농도와는 양의 상관성을 나타낸 반면 동맥경화지수와는 음의 상관성을 나타내었다. 이들 결과로 미루어 고혈압을 예방하기 위해서는 이상적인 체중유지와 더불어 혈청 지질 및 나트륨 농도를 저하시키고 혈장 아스코르브산 농도를 상승시키는 것이 필요할 것으로 사료된다.

This study was conducted to investigate the effects of brown rice and brown rice phytosterol on blood pressure and lipid levels in spontaneously hypertension rats (SHR). SHR were grouped according to blood pressure and fed either a control diet or experimental diets containing 50% brown rice powder or 5% brown rice phytosterol for 3 weeks. Body weight gain and epididymal fat weight were significantly reduced in the brown rice powder and brown rice phytosterol groups compared to control. Brown rice and brown rice phytosterol diets suppressed age-dependent increases in systolic blood pressure compared to control. In addition, brown rice and brown rice phytosterol diets decreased total lipid, triglyceride, and cholesterol levels in the liver, whereas serum HDL cholesterol increased. Lastly, brown rice phytosterol reduced TBARS contents in the kidney. These results suggest that brown rice and brown rice phytosterol exert antihypertensive effects that improve lipid metabolism in SHR.

This study was conducted to investigate the effects of Takju lees hot water extracts on the blood pressure in spontaneously hypertension rats (SHR). Twenty eight male SHR were grouped by their blood pressure and fed a control diet or experimental diets containing 1% (G1), 2% (G2), or 4% (G4) Takju lees extracts for 4 weeks. Food intake was not significantly different among the groups. However, body weight gain was significantly lower in groups fed the Takju lees extract than the control group. The systolic blood pressure was significantly lower in the Takju lees extract containing groups (especially in G4 group) than the control groups. In addition, mean blood pressure {(systolic+dyastolic)/2} decreased with an increase in the amount of Takju lees extract in the diet and feeding period. Takju lees extract decreased angiotensin I converting enzyme (ACE) activity in a dose-dependent manner. These results suggest that the Takju lees extract exert an antihypertensive effect by decreasing ACE activity.

Non processed onion (Allium cepa L.) powder or onion powder processed with β-cyclodextrin+1% calcium chloride+1% soluble starch solution was added to the diet of 16 week old Wistar and spontaneously hypertensive rats (SHR) for 5 weeks. 36 SHR and Wistar rats were randomly divided into 3 diet groups, each of six. They were named control, NPO (non processed onion), PO (processed onion). The rats of the control group were fed diet without onion powder. To NPO and PO groups were added 5% of non processed onion and processed onion, respectively. Body weight gain, food efficiency ratio (FER), blood pressure, angiotensin converting enzyme (ACE) activity and Na excretion of urine and feces were analyzed. The processed onion and non processed onion diet reduced body weight gain without affeting the total food intake in Wistar rats (p〈0.05). The body weight gain was lowest in Wistar rats fed with a diet with processed onion powder. The rats fed with diet containing PO or NPO had lower blood systolic blood pressure in SHR (p〈0.05). The effect of onion powder on decreasing the blood pressure was not significant in Wistar rats. The ACE activity in lung was lowered in the SHR fed with either PO or NPO (p〈0.05) compared to those fed with control diet. The urinary Na excretion was significantly lower in SHR than Wistar rats. The effects of PO and NPO on increasing the urinary and fecal excretion of Na were significant (p〈0.05). These results suggest that onion processed with β-cyclodextrin+1%+1% calcium chloride+1% soluble starch solution to reduce volatile flavor, browning and caking preserves an antihypertensive effect of non processed onion.

This Study aims at looking into the use of oriental medical services in treating hypertension. The first objective to be explored through this study is the morbidity caused by the disease, classifying them by age, gender, and occupation. The second is to determine the regular use of anti-hypertensive medicine and their efficacy in controlling blood-pressure. The third is to investigate the use-rate and satisfaction of oriental medical service. 838 households across the country, were asked to answer questionnaires for the period of time from Apr. to Jun. 2005. The conclusion from the survey can be summarized as following. The age of which the first medical diagnosis of hypertension were made showed lower in males, those with higher education and income. The study showed females were more active in blood-pressure control, with their frequent monitoring of blood-pressure for the past year. With age, people in under 50 age group proved to be less active. The management of high blood pressure was more effective in group with regular dosage compared to group with irregular use of anti-hypertensive medication, but their difference was minimal. Also, group with no medication showed signs of blood-pressure control. The use of oriental medical service for the past year, were more frequent in groups with lower education, either low or high income, old age, females and occupations in agriculture, forestry and fishing industry. Results were similar in both general population and high blood-pressure patient group. Females, people over 51 years old and with lower education showed more intentions in utilizing oriental medical services in the future. Results were similar in both general population and high blood-pressure patient group. It is necessary to offer a more accurate information on oriental medical treatments. Also, a systematic reform to reduce the patient's share of the treatment cost, as well as, heightening public awareness on the infirmity of present blood-pressure management system is crucial.

The aim of the experiments was to investigate the effect of Fructus Tribuli on the blood pressure, plasma renin activity, plasma levels of aldosterone and atrial natriuretic peptide (ANP) in spontaneously hypertensive rats (SHR). The results of this study were as follows: 1. Systolic blood pressure decreased significantly after the administration of Fructus Tribuli water extract 0.03 ㎖/200 g. 2. Plasma renin activity and plasma levels of aldosterone were not changed after the administration of Fructus Tribuli water extracts. 3. Plasma levels of atrial natriuretic peptide (ANP) decreased significantly after the administration of Fructus Tribuli water extracts.

This study was conducted to analyze the effects of horticultural therapy program based on health care education on quality of life, stress, depression and anxiety of hypertensive patients, and to find effects on ability to control hypertension by continuing health care education and horticulture education. Subjects were 60 adult hypertension patients aged 30 to 64 at a hospital in K-gu, Seoul, aged 30 to 64. Experimental group of 30 patients received horticultural therapy program and control group of 30 patients did not receive horticultural therapy program. The horticultural therapy program was conducted for 60 minutes per session, twice a week, and total 8 times. This study was performed from 1. Aug. to 31. Oct. in 2015. Each session was based on contents of basic health care education and horticultural education. The programs were verified by 5 specialists in related fields (1 doctor, 2 nurses, 2 horticultural therapists). To prove effects of horticultural therapy program, patients’ stress, depression, anxiety, quality of life and knowledge of hypertension and horticulture were estimated 3 times(before, after and 1 month after the experiment). SPSS (Version 22 for Windows) was used for t-test of independent sample, which analyzes demographic information and verifies homogeneity, and for t-test of matching sample which shows different effects between groups. As the results, horticultural therapy program based on health care education made significant positive effects on stress and quality of life of hypertensive patients. Moreover, the horticultural therapy program improved knowledge on horticulture and hypertension. However, there were no significant changes in control group. This result shows that the horticultural therapy program based on health care could relive stress and improve quality of life.