Hypertension caused by high-fat and high-salt diets is is a well-known significant risk factor for cardiovascular and cerebrovascular diseases. In this study, to confirm the relationship between hypertension and immune cells, angiotensin (Ang) II was administered to Dahl salt-sensitive (SS) rats and Dahl salt-resistant (SR) rats. Then the expression of immune cells and the proinflammatory cytokines were compared between the SS and SR rats. It was observed that after administration of Ang II (50ng/kg/min) for three weeks, blood pressure was increased in the SS rats, but there was no significant change in the SR rats. In addition, the expression of T helper (Th) cells and Th 17 cells in the spleen and the expression of Th cell Rorγt and regulatory T regulatory (Treg) cells in the peripheral blood mononuclear cells did not show a significant difference between the two experimental groups even after the administration of Ang II.IL-1β expression was significantly increased in the kidney tissue of the SS rats, while there was no significant difference in the IL-6 expression in all the experimental groups. The results of this study suggest that Ang II induces hypertension by stimulating IL-1β secretion from renal macrophage in SS rats.

본 연구의 목적은 고혈압 및 당뇨병을 진단 받은 성인의 뇌졸중 및 심근경색증의 조기 증상 인지 정도를 파악하고 비인지와 관련된 요인을 분석하기 위함이다. 2017년 지역사회건강조사 원시자료를 활용하여, 40세 이상 성인 12,277명의 자료를 분석하였다. 뇌졸중 및 심근경색증의 조기 증상 인지율은 각각 53.6%와 46.8%였다. 뇌졸중 및 심근경색증 조기 증상 비인지 요인을 평가하기 위해 로지스틱 분석을 수행 하였다. 고혈압 관리 교육, 혈압 수치 및 당화혈색소 수치 인식은 다변량 분석에서 인구사회학적 변수를 보정한 후에도 뇌졸중 조기 증상 비인지와 유의한 관련이 있었다. 혈압 수치 및 당화혈색소 수치 인식은 심근 경색증 조기 증상 비인지와 유의한 관련이 있었다. 그러므로 고혈압과 당뇨병을 모두 관리해야 하는 고위험군에 대한 홍보 촉진 및 교육 강화 등 심뇌혈관질환 조기 증상 인지 수준 개선을 위한 중재 및 전략의 개발이 요구된다.

Gastrodia elata Bl. (GE) is a traditional herbal medicine used for the treatment hypertension and cerebrovascular disease. The purpose of this study was to investigate the antioxidant effect and blood pressure control ability of the GABA containing fermented Gastrodia elata Blume. The fermentation strain provided by Dr. Gi in Seoul National University is L. brevis GABA100, excellent strain of GABA production, which is involved in the ability to degrade gastrodin glycosides and activation of brain function. The Gastrodia elata Blume fermented by Lactobacillus brevis GABA 100 showed antioxidant activity (total phenolic contents, DPPH radical and ABTS anion scavenging activities) than unfermented Gastrodia elata Blume. In the spontaneously hypertensive rats (SHR), the concentration of fermented Gastrodia elata Blume was administered at 500, 1,000, and 2,000 mg/kg for 8 weeks. Systolic blood pressure decreased statistically significantly (p<0.05), especially 2 weeks after feeding fermented Gastrodia elata Blume. Also, it showed a significant decrease in low, medium, and high concentrations of fermented Gastrodia elata Blume at 4 weeks and 8 weeks. These results indicated that Gastrodia elata Blume fermented by the excellent strain of GABA production L. brevis GABA100 shows the antioxidant function and the effect of suppressing the increase in blood pressure.

본 연구는 장애인 복지관을 이용하는 지체장애인 및 뇌병변장애인 중 고혈압 환자를 대상으로 복지관 간호사와 간호학생 자원봉사자를 통해 제공된 8주 전화상담 고혈압 자가관리 프로그램의 효과를 파악하는데 목적이 있다. 비동등성 대조군 전후 유사실험설계 연구로, 2019년 12월부터 2020년 5월까지 사전, 사후 조사를 완료한 대조군 28명, 실험군 29명의 자료를 SPSS 프로그램을 이용하여 분석하였다. 주요 연구결과로, 프로그램 적용 후 실험군이 대조군에 비해 고혈압 관련 지식, 건강신념 중 심각성과 민감성, 삶의 질 EQ-VAS에서 통계적으로 유의한 차이를 나타나며 높아진 것으로 나타났다. 따라서 장기적인 건강관리가 필수적인 장애인 고혈압 환자를 대상으로 다양한 자가관리 프로그램을 적용하여 관련 지식, 건강신념 및 삶의 질 등을 높이는 노력이 계속적으로 필요할 것이다.

본 연구는 고혈압 환자의 생활습관 조절 코칭프로그램 개발을 위한 탐색적 연구를 통하여 고혈압을 낮추는 생활습관으로 좀 더 건강한 생활을 유지하도록 하는 것에 목적이 있다. 본 연구는 고혈압환자의 생활습관과 코칭에 관한 선행연구를 탐색하여 생활습관조절의 구성요소와 코칭모델 및 코칭의 기술 그리고 고혈압 환자의 요구도 조사 내용을 바탕으로 총 12회기의 프로그램으로 구성하였다. 또한 영양학과 간호학, 스포츠레저학 및 코칭전문가의 자문을 거쳐 교육, 적용, 평가단계로 구성하였고, ACTIVE 코칭 대화모델과 코칭기술 및 생활습관 내용을 바탕으로 구성하였다. 이 과정에서 사용된 코칭모델은 CPA모델이며, 코칭대화모델은 C-PLUS코칭원리를 바탕으로 한 ACTIVE코칭 대화모델이다. 구체적인 프로그램은 고혈압에 대한 이해, 고혈압 환자의 실천습관, 코칭에 대한 기초, 코칭의 원리, 코칭대화모델, 코칭의 기술로 구성하였다. 본 연구에서 탐색한 고혈압 환자 생활습관 조절 코칭프로그램은 고혈압환자의 고혈압수준을 낮추고 보다 건강한 생활을 유지하는 생활습관을 형성하기 위한 프로그램으로 코칭프로그램을 개발하고 타당화하는데 기초 자료를 제공하고, 이와 관련된 연구를 위한 기본적 틀을 제공하는데 의의가 있다.

The purpose of this study is to identify awareness of hypertension prevalence among Korean youth and related causes. Data from the Korean National Health and Nutritional Examination Survey, conducted in 2016 by the Korea Centers for Disease Control and Prevention, were used to apply weights for complex sample analysis. A total of 1,075 data age 19~35 Korean youth were used for analysis. The analysis demonstrated that 25.7% of age 19~35 Korean youth were in the prehypertension stage and 6.1% were in the hypertension stage. Those aware of hypertension was 0.3%. This revelation necessitates establishment of preventive measures by way of physical examination among youth to ensure no youth are left untreated in terms of health management. This study indicated that diabetes affects hypertension significantly among males (p<0.0001), with low income (p=0.034) and obesity (p<0.0001). Consequently, they should be managed as high-risk, and it is imperative to educate them about changes in lifestyle such as walking or less dining-out, rather than engaging in specific sports activities or nutrient intake.

This study was designed to investigate dietary life related to sodium of participants in hypertension and diabetes preventive education at the public health center located in Incheon Metropolitan City. Subjects were comprised of 301 adults (males: 102, female: 199) of age 50 years and above. The questionnaire for dietary life and salty taste assessment were performed on the subjects. Data were analyzed using SPSS package (ver. 18.0). According to the result of questionnaire for dietary behavior, 70% of the subjects were in the low salt intake group (p<0.001). In the result of questionnaire for dietary frequency, all ages groups were in the low salt intake group (p<0.01). The data of questionnaire for dietary behavior showed that the subjects of age above 75 years preferred salted seafood, soup, and kimchi (p<0.01). The data of questionnaire for dietary frequency showed that the subjects of age between 65 and 74, least chose fried kimchi, noodle, and soybean paste soup with clams (p<0.05), and the healthy adult groups chose kimchi stew, ssam and ssamjang (p<0.05). The score for dietary behavior in male subjects was higher than female subjects (p<0.01). In particular, the score for dietary frequency was the lowest in the subjects of age between 65 and 74 (p<0.01). The mean value of salty taste assessment in the subjects was 0.41% which is higher than the ideal value of 0.3% (p<0.01). Offering more nutrition education and continuous feedback of healthcare center may be needed to improve the health status of the adults.

This study was conducted to investigate the effects of brown rice and brown rice phytosterol on blood pressure and lipid levels in spontaneously hypertension rats (SHR). SHR were grouped according to blood pressure and fed either a control diet or experimental diets containing 50% brown rice powder or 5% brown rice phytosterol for 3 weeks. Body weight gain and epididymal fat weight were significantly reduced in the brown rice powder and brown rice phytosterol groups compared to control. Brown rice and brown rice phytosterol diets suppressed age-dependent increases in systolic blood pressure compared to control. In addition, brown rice and brown rice phytosterol diets decreased total lipid, triglyceride, and cholesterol levels in the liver, whereas serum HDL cholesterol increased. Lastly, brown rice phytosterol reduced TBARS contents in the kidney. These results suggest that brown rice and brown rice phytosterol exert antihypertensive effects that improve lipid metabolism in SHR.

The purpose of the study was to investigate the effectiveness of self-paced walking exercises in elderly women with hypertension, hyperglycemia, and hypercholesterolemia. Thirty-eight elderly women with hypertension, hyperglycemia, and hypercholesterolemia (16 hypertension, 11 hyperglycemia, 11 hypercholesterolemia), aged between 65 and 80, were invited to participate in this study. Each subject participated in a self-paced walking exercise five times a week for twelve weeks from 26 June to 16 September 2006. The changes between pre- and post-exercise were analyzed using the analysis of a paired t-test with the SPSS version 12.0 package program. There were significant decreases in systolic blood pressure (p<.01) and diastolic blood pressure (p<.05), blood glucose(p<.05), and cholesterol in the blood (p<.01). These results show that self-paced walking exercises may be helpful in treating elderly women with hypertension, hyperglycemia, and hypercholesterolemia.

The purpose of this study is to compare the correlation of clinical characteristics and patterns of disease. Subjects of the study were the adults(207) living in Geoje City, the diabetes mellitus and the hypertension patients(166) and the normal people(41). In the diabetes mellitus group and the hypertension group, blood pressure, blood glucose, total cholestero LDL-cholesterol and atherogenic index(AI) were significantly high. As the obesity index was getting higher, the blood pressure of the diabetes mellitus group was high, and the HDL-cholesterol of the hypertension group was low, but AI of it was significantly high. The AI was significantly high as serum lipid index were getting higher in both groups. The rate of the prevalence was very high in the diabetes mellitus group(74.3%) and the hypertension group(73.7%). The pattern in the diabetes mellitus group was in order of the hypertension, the hyperlipidemia, and the obesity but, in the hypertension group was the hyperlipidemia, and the obesity. The obesity index and serum lipid index of complex patient group were higher than single patient group.

Iridology, developed more than 100 years ago, is the diagnosis of medical conditions through noting irregularities of the pigmentation in the iris The purpose of this study is to compare interrelation between CVA, hypertension family history and cardio-renal connective tissue in Iris Constitution through iris constitution examination. The subjects consist of 114 patients who were examined in Iris Constitution at Chonju Oriental Medicine Hospital attached to Wonkwang Univ. from September. 1st. 2000 to August. 31th. 2002. 1. In the distribution of Iris Constitution, among of 79cases, There are neurogenic type 13cases, abdominal connective tissue weakness constitution 31 cases, cardio-renal connective tissue weakness constitution 6 cases, cholesterol 7 cases and others 22 case in control group. 2. There are familial history of CVA and hypertention 32 cases, no familial history of CVA and hypertention1 3 cases, in 35cases of experimental group. These results imply that there is meaningfulness of interrelation between cardio-renal connective tissue weakness constitution and CVA, hypertention.

In treatment of right ventricular failure with pulmonary hypertension, milrinone has not only an inotropic effect but also a vasodilating effect, thus, recently, it has been widely used. Recent studies have reported on the direct stimulation effects of doxapram on the central nervous system. A 91-year-old female underwent hemiarthroplasty under spinal anesthesia. When transported to the recovery room, right ventricular failure, cardiogenic shock, and mental deepening occurred. After stabiliz-ing vital signs, milrinone, doxapram was administered. We report on the effective use of milrinone for acute right ventricular failure and the active use of doxapram for reduced consciousness and hypoventilation.

Wished to measure and analyzes blood pressure change of that walk forest walking path to woman among slight illness hypertensive who move into silver town and when walked asphalt walking path so that this study searches positive effect about that it so that may recognize widely positive side through that walk for blood pressure coercion of hypertensives exercise do and walks in forest exercise and clear benefit of forest walking path. Through this study, proved study finding is as following. 1) Exercise to walk estimates distance more than minimum 1200m that can see positive effect though do exercise. 2) According to result that blood pressure change of asphalt walking path and forest walking path does comparative analysis, significance probability was recognized at systolic blood pressure, and change of blood pressure was recognized significance probability at systolic blood pressure after exercise on the forest walking path. 3) Result that woman old man and slight illness high blood pressure old man woman blood pressure does comparative analysis, forest walking path after exercise in contraction period, relaxation period blood pressure significance probability recognize. These result estimates by thing which it can maximize effect of exercise that walk on the forest walking path that do exercise. 4)Appeared by thing which synonymy is between sequence, two circles that emotion state on forest walking path and asphalt walking path does comparative analysis, and change of emotion state was recognized significance probability in the most articles after forest walking path exercise. This can judge kinetic effect that keep emotion state that can maximize in case of do exercise on the forest walking path. This studies are giving effect that walk exercise is positive in old man woman's body, but examines closely that the floor was displaying effect that was surrounded by the tree than hard asphalt walking path and walks on forest walking path of soft earth road exercise is positive in body and confirmed necessity of forest walking path.