Because intact FMDV particles (146S) are often unstable in vitro, stabilizing foot-and-mouth disease virus (FMDV) antigens remains a key challenge in studying viral charateristics. Therefore, finding optimal condition to stabilize the FMDV is essential. In this study, we investigated formulations and potentials of several stabilizers such as appropriate buffer, excipients, and storage conditions to enhance the stability of 146S. Inactivated FMDV O-Jincheon (O-JC) was dissolved in various buffer formulations, and stored at 4℃ for two months to evaluate quantity of 146S at every 2-week interval. Among phosphate buffered saline (PBS), Tris buffered saline (TBS), HEPES buffered saline (HBS), and MOPS buffered saline (MBS), PBS showed more effective 146S stabilization that showed 1.3-1.6 fold higher 146S fraction than TBS, HBS, and MBS after storage for 2 weeks. However, constant dissociations of 146S were observed in all formulations at 8 weeks. Compared with other FMDVs, A22 Iraq and SAT-1, in PBS, O-JC proved to be the least stable in PBS. A variety of excipients including carbohydrate, sugar alcohol, cryo-protectant were tested for the capability in protecting O-JC from dissociation. By adding 4-8% sucrose, more than 60% of 146S fractions were maintained at 8 weeks, those were at least 1.8 fold higher than the PBS-only control. Addition of 1% β-cyclodextrin showed synergistic enhancement in O-JC stability. As the results of this study, it could be suggested that the PBS-based buffer together with 4-8% sucrose + 2% sorbitol or 2% sucrose + 2% sorbitol + 1% β-cyclodextrin could help the better stability of the O-JC in vaccine preparation.

In this study, ester co-solvents and fluoroethylene carbonate (FEC) were used as low-temperature electrolyte additives to improve the formation of the solid electrolyte interface (SEI) on graphite anodes in lithium-ion batteries (LIBs). Four ester co-solvents, namely methyl acetate (MA), ethyl acetate, methyl propionate, and ethyl propionate, were mixed with 1.0 M LiPF6 ethylene carbonate:diethyl carbonate:dimethyl carbonate (1:1:1 by vol%) as the base electrolyte (BE). Different concentrations were used to compare the electrochemical performance of the LiCoO2/ graphite full cells. Among various ester co-solvents, the cell employing BE mixed with 30 vol% MA (BE/MA30) achieved the highest discharge capacity at − 20 °C. In contrast, mixing esters with low-molecular-weight degraded the cell performance owing to the unstable SEI formation on the graphite anodes. Therefore, FEC was added to BE/MA30 (BE/MA30-FEC5) to form a stable SEI layer on the graphite anode surface. The LiCoO2/ graphite cell using BE/MA30-FEC5 exhibited an excellent capacity of 127.3 mAh g− 1 at − 20 °C with a capacity retention of 80.6% after 100 cycles owing to the synergistic effect of MA and formation of a stable and uniform inorganic SEI layer by FEC decomposition reaction. The low-temperature electrolyte designed in this study may provide new guidelines for resolving low-temperature issues related to LIBs, graphite anodes, and SEI layers.

Onboard truck scales can accurately measure payload under static conditions. However, their performance is limited in accounting for dynamic environments encountered during driving, leading to inaccuracies in load estimation under real-world conditions. This study employs TruckCaliber, a dynamic state measurement system, to estimate real-time vehicle loads. Fusion sensor modules were installed on leaf spring suspensions and vehicle frames to collect tilt and IMU data. The system was implemented on a commercial truck, and driving tests were conducted with varying payloads. The analysis focused on curved sections under different dynamic conditions.

In this study, we utilized a multi-step stabilization method, incorporating dry-oxidation, to produce high-density polyethylene (HDPE)-based activated carbon fibers. This stabilization was achieved through electron-beam irradiation, sulfonation, and dry oxidation. The stabilized fibers were carbonized and activated at 900 ℃. The crystallite characteristics of the activated carbon fibers were observed using X-ray diffraction, and their surface morphologies were analyzed through scanning electron microscopy. The textural properties were analyzed using N2/ 77 K adsorption–desorption isothermal curves. And leveraging the microdomain model, we explored the influence of these stabilization methods on the HDPE-based activated carbon fibers texture properties. The results show that HDPE fibers treated with sulfonation only at 100 ℃ for 60 min were not sufficiently cross-linked and were completely decomposed during the carbonization stage. However, the sulfonated fibers treated with the new dry-oxidation process maintained their shapes and were successfully activated. The specific surface area of the resulting activated carbon fibers was as much as 2000 m2/ g.

Background: The Trunk Stabilization Exercise and Respiratory Muscle Exercise may help address the complex biomechanical and neuromuscular issues that contribute to shoulder joint disorders and can help improve patient outcomes in terms of pain relief, range of motion, and functional ability. Objectives: To investigated the effects of conventional physical therapy, trunk stabilization exercise, and respiratory muscle exercise, on the Range of Motion (ROM), ULF and balance in patients with shoulder joint disorder. Design: A randomized controlled trial. Methods: This study randomly allocated 18 subjects to the control group, 19 to the trunk stabilization exercise group, and 19 to the respiratory muscle exercise group, while all interventions were performed five times a week for four weeks. The result measurement involved the ROM, the upper limb function test (ULT), and balance tests. Results: The respiratory muscles exercise group indicated significant improvement in ROM and balance tests than the trunk stabilization exercise group and control group. Conclusion: The respiratory muscle exercise is a more effective way to improve ROM and balance ability than trunk stabilization exercise for patients with shoulder joint disorder.

Background: People these days use smartphone extensively as a means of diverse social activities, but excessive use of it has also created increasing forward head posture (FHP) with neck pain. To improve this FHP, neck stabilization exercise is necessary. Objectives: This study was to investigate the effects of stabilization exercise using biofeedback on FHP subjects with neck pain. Design: A non-randomized, controlled intervention study. Methods: This study chose 18 college students in their 20s whose neck disability index (NDI) was equal to or higher than 10 and cranio-vertebral angle indicated FHP as experimental group. The control group selected 18 persons with no neck pain and a normal range of cranio-vertebral angle. The stabilization movement was performed by applying three phases of pressure, with low of 20 mmHg, intermediate of 25 mmHg, and high of 30 mmHg, using the Stabilizer. To check the effects of stabilization exercise according to pressure, the circumference of deep neck muscles was measured with ultrasonic waves, and the activity of surface muscle of sternocleidomastoid (SCM) was measured using electromyography (EMG). Results: When the circumference of the deep neck flexor was analyzed according to the pressure change during stabilization exercise, the experimental group showed increase at all pressures. The activity of the SCM of the surface muscle increased in both groups as the pressure increased. Conclusion: The application of stabilization exercise was found to be more effective on forward head posture subjects with neck pain at lower pressures.

Background: Scapular dyskinesis may cause not only rotator cuff (RC) tear but also weakness of the upper extremity, studies on scapular dyskinesis that may occur after RC repair is still lacking. Objects: To determine whether scapular dsykinesis was present in patients after arthroscopic RC repair and to investigate the influence of passive scapular stabilization on upper extremity strength. Methods: A total of 30 patients after RC repair participated in this study. To compare the scapula of the arthroscopic RC repair shoulder and the contralateral shoulder, the winged scapula (WS) was measured using a scapulometer and scapular dyskinesis was also classified by type. Fixed instruments for muscle strength measurements were used to measure upper extremity muscle strength differences depending on passive scapular stabilization position or natural scapular position. A chi-square test, an independent t-test and a 2-way mixed measures analysis of variance (ANOVA) was used as statistical analysis. In analyses, p < 0.05 was deemed to be statistically significant. Results: Postoperative shoulder had a significant association with scapular dyskinesis and the WS compared to the contralateral shoulder (F = 0.052, p < 0.01). Postoperative shoulder, muscle strength in the shoulder abduction (p < 0.01), elbow flexion (p < 0.01) and forearm supination (p < 0.05) were significantly greater in the scapular stabilization position than in the scapular natural position. Conclusion: Patients underwent arthroscopic RC repair had a significant association with scapular dyskinesis and muscle strength was improved by a passive scapular stabilization position, therefore scapular stabilization is important in rehabilitation program.

본 연구에서는 만성요통을 가진 여성노인의 체형 및 요부안정화를 위해 12주간 필라테스 운동 프로그램을 적용한 후 체형에 미치는 영향을 알아보고, 통증의 변화를 규명함으로써 노화를 늦추고 신체활 동 영역을 높일 수 있는 노인에게 적합한 운동 프로그램 개발에 필요한 자료를 제공하고자 하였다. 이에 3~5cm 중증도 통증범위의 만성요통을 가진 16명여성노인을 대상으로 주관적 통증척도지를 통해 실험집단 8명, 통제집단 8명을 단순무선표집(Simple Random Sampling)으로 선정하였다. 요부안정화 필라테스 운동 프로그램은 주 2회씩 총 12주간 50~60분간 실시하였으며, 1세트 종료 시 1분 휴식을 주는 방식으로 실시 하였다. 그 결과 첫째, 체형 및 통증에서는 경추 기울기에서 요부안정화 운동그룹의 경우 운동 전에 비해 감소하였으나 통제집단은 증가하였다. 둘째, 요부 통증의 결과 운동집단의 경우 운동에 비해 감소하였으나 통제집단은 증가하였다. 결론적으로 요부안정화 필라테스 운동은 만성요통을 가진 여성노인에게 있어서 통 증을 감소시킬 수 있는 프로그램으로 적용될 수 있으며, 체형을 개선시키는데 도움을 줄 수 있는 것으로 확인되었다.

Reactive oxygen species (ROS) production and F-actin cytoskeleton dynamics play important roles in the survival rate of blastocysts after the vitrifiedwarming process. However, the protective effects of Mito-TEMPO against cryo-injury and viability through F-actin aggregation and mitochondrial-specific ROS production in vitrificated-warmed bovine embryos have not been investigated. The aims of the present study were to: (1) determine the effects of Mito-TEMPO on embryonic developmental competence and quality by F-actin stabilization during in vitro culturing (IVC), and (2) confirm the effects of Mito-TEMPO through F-actin structure on the cryotolerance of vitrification-warming in Mito-TEMPO exposed in vitro production (IVP) of bovine blastocysts. Bovine zygotes were cultured with 0.1 μM Mito-TEMPO treatment for 2 days of IVC. Mito-TEMPO (0.1 μM) exposed bovine embryos slightly improved in blastocyst developmental rates compared to the non-treated group. Moreover, the viability of vitrified-warmed blastocysts from Mito-TEMPO treated embryos significantly increased (p < 0.05, non-treated group: 66.7 ± 3.2% vs Mito-TEMPO treated group: 79.2 ± 5.9%; re-expanded at 24 hours). Mito-TEMPO exposed embryos strengthened the F-actin structure and arrangement in the blastocyst after vitrification-warming. Furthermore, the addition of Mito-TEMPO into the IVC medium enhanced embryonic survival and quality through F-actin stabilization after the vitrification-warming procedure. Overall, our results suggest that supplementing the culture with 0.1 μM Mito- TEMPO improves the embryonic quality and cryo-survival of IVP bovine blastocysts.

Carbon fibers (CFs) are considered promising composite materials for various applications. However, the high cost of CFs (as much as $26 per kg) limits their practical use in the automobile and energy industries. In this study, we developed a continuous stabilization process for manufacturing low-cost CFs. We employed a textile-grade polyacrylonitrile (PAN) fiber as a low-cost precursor and UV irradiation technique to shorten the thermal stabilization time. We confirmed that UV irradiation on the textile-grade PAN fibers could lower the initial thermal stabilization temperature and also lead to a higher reaction. These resulted in a shorter overall stabilization time and enhancement of the tensile properties of textilegrade PAN-based CFs. Our study found that only 70 min of stabilization time with UV irradiation was required to prepare textile-grade PAN-based low-cost CFs with a tensile strength of 2.37 ± 0.22GPa and tensile modulus of 249 ± 5 GPa.

This study evaluated the synthesis of optimal materials for high efficiency adsorption and removal characteristics of Cs-137 for radioactive contaminated water, and considered thermal treatment methods to stabilize the spent adsorbent generated after treatment. We synthesized a composite adsorbent with a combination of impregnating metal ferrocyanide that improves the selectivity of Cs adsorption with zeolite capable of removing Cs as a support. The Cs removal efficiency of the composite adsorbent was evaluated, and the stability change of Cs according to the high-temperature sintering was evaluated as a stabilization method of the spent adsorbent. The metal ferrocyanide content of the adsorbent was in the range of 11.8~36.0%. The adsorption experiments were performed using a simulated liquid waste to have a total Cs concentration of 1 mg/L while containing a trace amount of Cs-137, and then gamma radioactivity was analyzed. In order to evaluate the stabilization of the spent adsorbent, heat treatment was performed in the range of 500~1,100°C, and the volatilization rate of Cs during heat treatment and the leaching rate of Cs after heat treatment were compared. In the adsorption experiment, the Cs removal efficiency was higher than 99%, regardless of the amount of metal ferrocyanide in the composite adsorbent. In the sintering experiment on the spent adsorbent, it was confirmed that there was no volatilization of Cs up to 850°C, and then the volatilization rate increased as the heating temperature increased. On the other hand, the leaching rate of Cs in the sintered adsorbent tends to significantly decrease as the heating temperature increases, so that Cs can be stabilized in the sintered body. In addition, as the content of metal ferrocyanide increases, the volatilization rate of Cs rapidly increases, indicating that the unstable metal ferrocyanide in the adsorbent may adversely affect the removal of Cs as well as the thermal treatment stability.

Irradiated uranium dioxide in damaged used fuel could oxidize during transportation, interim storage or disposal, resulting that the fuel pellet fragments are reduced to a grain-sized powder that can easily escaped from the damaged rod. It has been reported that oxidized spent fuel (i.e. U4O9+x) that was in contact with water could increase the dissolution rate by making the grain boundaries more accessible to the water. Therefore, the damaged used fuel requires stabilization technology including nuclear material recovery, pellet manufacturing process, and stabilization fuel rod manufacturing that can secure safety in terms of permanent disposal. In this study, we prepared pure UO2 and SIMFUEL pellets that are a mixture of UO2 and surrogated metallic oxides for fission products equivalent to a burn-up of 35 GWd/tU and 55 GWd/tU as the stabilized spent fuel. The UO2 and fission products powders were milled and pressed into pellets at 250 MPa and sintered at 1,550°C and 1,700°C for 6 hours in an atmosphere of 4%H2-Ar. The prepared UO2 and SIMFUEL pellets were placed in PTFE Teflon vessels and filled with deionized water to identify the leaching behavior by a long-term leaching experiment under the similar condition to a repository for the safe disposal.

Background: Inspiratory muscle training can improve inspiratory strength and endurance through threshold loading. In addition, trunk stabilization exercises can improve trunk strength and respiratory function. Objectives: The purpose of this study is to investigate the effect of application of inspiratory muscle training and trunk stabilization exercise on pulmonary function and inspiratory muscle activation in college students. Design: Randomized controlled trials. Methods: In this study, 24 college students were randomly divided into two groups: inspiratory muscle training and trunk stabilization exercise (experimental group, n=12), and trunk stabilization exercise (control group, n=12). Inspiratory muscle activity was measured using a surface electromyography. Pulmonary function was measured using a spirometer and a peak expiratory flow meter. Results: In the experimental group, the muscle activity of both upper trapezius and latissimus dorsi muscles increased significantly after the intervention. In the experimental group, both upper trapezius muscle activity was significantly increased than in the control group. In the experimental group, all the pulmonary function significantly increased after the intervention. Conclusion: In this study, when the inspiratory muscle training was additionally applied to the trunk stabilization exercise in college students in their twenty, it was possible to improve the inspiratory muscle activity and pulmonary function.

Background: Previous studies have reported that improving the spinal stability could be more effective in the prevention and treatment of recurrence. Lumbar stabilization exercise is known to strengthen the lumbar extension muscles and enhance physical, psychological and social functions. Objectives: To investigated the effect of lumbar spiral stenosis on the kinetic link training and lumbar stabilization exercise. Design: A randomized controlled trial. Methods: Study was preformed by randomly allocated 28 LSS participants into a kinetic link training group (KLT, n=14) and a lumbar stabilization exercise group (LSE, n=14). Kinetic link training and lumbar stabilization exercise were performed to subjects in both groups 5 times a week for 6 weeks. To verify the effect of LSS, changes in VAS, ODI, and proprioception before and after intervention were observed. Results: In KLT, statistically significant changes were found in VAS, ODI, and Proprioception before and after intervention. In LSE, there were significant changes in VAS and ODI before and after intervention. KLT and LSE before and after intervention indicated significant differences in proprioception. Conclusion: KLT and LSE are applied to LSS, there are effects of pain decrease, lumbar recovery and proprioception improvement.

As the design life of nuclear power plants are coming to the end, starting with Kori unit 1, nuclear power related organizations have been actively conducted research on the treatment of nuclear power plant decommissioning waste. In this study, among various types of radioactive waste, stabilization and volume reduction experiments were conducted on radioactive contaminated soil waste. Korea has no experience in decommissioning nuclear power plants, but a large amount of radioactively contaminated soil waste was generated during the decommissioning of the KAERI research reactor (TRIGA Mark- II) and the uranium conversion facility. This case shows the possibility of generating radioactive soil waste from nuclear power plants and nuclear-related facilities sites. Soil waste should be solidified, because its fluidity and dispersibility wastes specified in the notification of the Korea Nuclear Safety and Security Commission. In addition, the solidified waste forms should have sufficient mechanical strength and water resistance. Numerous minerals in the soil are components that can make glass and ceramics, for this reason, glass-ceramic sintered body can be made by appropriate heat and pressure. The sintering conditions of soil were optimized, in order to make better economical and more stable sintered body, some additives (such as additives for glass were mixed) with the soil and sintering experiments were conducted. Uncontaminated natural soil was collected and used for the experiment after air drying. Moisture content, pH, bulk density, and organic content were measured to understand the basic properties of soil, and physicochemical properties of the soil were identified by XRD, XRF, TG, and SEM-EDS analysis. In order to understand the distribution by particle size of the soil, it was divided into Sand (0.05–2 mm) and Fines (< 0.05 mm). The green body was manufactured in the form of a cylinder with a diameter of 13mm and a height of about 10mm. Appropriate pressure (> 150 MPa) was applied to the soil to make a green body, and appropriate heat (> 800°C) was applied to the sintered body to make a sintered body. The sintering was conducted in a muffle furnace in air conditions. The volume reduction and compressive strength of the sintered body for each condition were evaluated.

The capacity of high nickel Li(NixCoyMn1-x-y)O2 (NCM, x ≥ 0.8) cathodes is known to rapidly decline, a serious problem that needs to be solved in a timely manner. It was reported that cathode materials with the {010} plane exposed toward the outside, i.e., a radial structure, can provide facile Li+ diffusion paths and stress buffer during repeated cycles. In addition, cathodes with a core-shell composition gradient are of great interest. For example, a stable surface structure can be achieved using relatively low nickel content on the surface. In this study, precursors of the high-nickel NCM were synthesized by coprecipitation in ambient atmosphere. Then, a transition metal solution for coprecipitation was replaced with a low nickel content and the coprecipitation reaction proceeded for the desired time. The electrochemical analysis of the core-shell cathode showed a capacity retention of 94 % after 100 cycles, compared to the initial discharge capacity of 184.74 mA h/g. The rate capability test also confirmed that the core-shell cathode had enhanced kinetics during charging and discharging at 1 A/g.