The purpose of this study is to propose the methodology for introducing green infrastructure that can improve the health of citizens by promoting walkability. The methodology is composed of the following three phases: classification of the types of green spaces, selection of core green spaces with two separate analyses, and introduction of the framework of green infrastructure to promote walkability. In the first phase, the classification of the types of green spaces was carried out in order to understand existing distribution pattern of green spaces in study site. In the second phase, walkable blocks were selected by such methods as walkability value. Through these two analyses, all the blocks were divided into three groups according to the ranking figured up the second analyses' results. The blocks in the first group, the group involved in the top 30% and having the greatest ranking, were defined as walkable blocks. In the last phase, a basic frame of the green infrastructure in study site was introduced by connecting the walkable blocks with using other blocks and the green spaces over 1ha. In case study, 28 important green spaces and 35 walkable blocks were selected through the two analysis process. Then, the basic framework of green infrastructure based on the selected 28 important green spaces and 35 walkable blocks was introduced. The methodology applied to this study can be used to get the best selections of the proper green infrastructure in accordance with the purpose of the ecological and recreational local development. In particular, this study will suggest a specific analysis model to use for the ecological and walkable urban planning with green spaces existing in the city.

Although hair disorders are not life threatening, a lot of people who suffer hair loss and/or hair thinning is increasing in accordance with changes in lifestyle and nutritional balance. The aim of this study was to examine the effects of herbal extracts on hair regrowth in C3H/HeJ mice. There were 6 experimental groups including distilled water (D.W.), 50% ethanol (a vehicle control), 3% minoxidil (a positive control), and 3 kinds of herbal extracts mixtures (C, D & E). The test compounds included followings; C : Glycyrrhizae radix, Rhei Rhizoma, Cornus officinalis and Sesami semeni, D : Viticus fructus, Pulsatilla chinensis, Gardenia fructus and Artemisiae argyi herb, E : Swertia pseudo-chinensis, Sophora flavescens Scutellaria baicalensis and Salvia miltiorrhiza. The animals were shaved with an electric clipper. The test compounds were daily treated to dorsal skin with 0.2 ml per mouse for 3 weeks. The topical application of the E test solution accelerated hair regrowth after 10 days faster than that of the positive and vehicle controls. The activities of alkaline phosphatase (ALP) and γ-glutamyl transpeptidase significantly were increased in all the treatment groups after 3 weeks, compared with D.W. group. Especially, the E test solution notably increased ALP activity compared with positive or vehicle control group. Epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF) were increased in all the treatment groups after 3 weeks compared with D.W. group. These results suggest that the herbal extracts have hair regrowth effect by increasing enzyme activities and growth factors and it can be useful for treatment for alopecia in humans.

This study was carried out to investigate effect of herbal extracts mixtures on hair growth in an alopecia model of C57BL/6 mice. There were 4 experimental groups including distilled water (DW, negative control), 25% ethanol(EtOH, vehicle control) and two herbal extract mixtures (HE-1 and HE-2). HE-1 included Polygonum and Brassica campestris extracts and HE-2 included Mulberry root and Gardenia extracts. The 6 weeks-old C57BL/6 male mice were shaved with an electric clipper and the test compounds were topically treated with 0.2 ml per mouse daily for 3 weeks. The hair re-growth was photographically determined at days 0, 4, 7, 10, 14, 17, and 21. The number of mast cells which is an important modulator of hair growth was counted in 1 cm of dorsal skin section of mice. There were no clinical signs in all experimental groups. As the results of photometric analysis, the topical application of the herbal extracts (HE-1 & 2) for 2 weeks to dorsal skin accelerated hair re-growth remarkably faster than that of DW group (p＜0.05). Activity of alkaline phosphatase (ALP) was significantly increased in EtOH group compared to DW group (p＜0.05). Both herbal extract mixtures also increased the ALP activity, but it was not significantly different from DW. Treatment of mice with HE-2 significantly increased mast cell population compared to EtOH. Taken together, these results suggest that herbal extract mixtures used in this study may have hair-growth promoting activities and can be useful for treatment for male pattern baldness or alopecia in humans.

본고에서는 지난 1990년부터 추진된 포동 개발·개방의 배경과 목적, 추진 과정에서 등소평의 역할, 구체적인 추진 방식, 네 개의 핵심 기능클러스터의 형성 등을 중국의 최근 자료에 기초하여 상세히 고찰하였다. 1990년 개발·개방을 시작한 이래 포동신구의 경제는 경이적인 고성장을 계속하였다. 포동의 GDP는 1990년의 60.2억 위안에서 2006년에는 2,365억 위안으로 급증해, 16년간 연평균 18.4%의 실질성장을 기록하였다. 또 2006년 말까지 외국인 직접투자 계약건수는 1만 4,910개, 계약금액은 357.1억 달러에 이르렀다. 타 성·시에서 투자한 국내기업도 9,300여 사이고, 등록자본은 600억 위안에 이르렀다. 그 결과 전형적인 농촌지역이었던 포동은 이제 외향형, 다기능의 현대화된 신도시로 바뀌었다. 이제 포동은 중국 전역에서 가장 경제발전 수준이 높고, 주변에 대한 파급력이 강하며, 가장 개방적이고 국제화된 지역의 하나가 되었다. 포동의 개발·개방을 계기로 1990년대 이후 장강삼각주 경제권은 전체 중국경제의 새로운 중심으로 부상하게 되었다. 몇 가지 문제점이 없는 것은 아니지만, 전체적으로 볼 때 지난 15~16년간 포동의 개발·개방은 매우 성공적이었다고 평가할 수 있다.

Consumers keep demanding for diversified high quality products, valuable services and safety. With this in mind, Distribution Industry is being updated rapidly to accomodate this demand. Meanwhile, Distribution Information Technology of agricultural products has been in slow progress with little in-depth studies. In this study, it has been analyzed the usage of Bar code which is the key element for agricultural Distribution Information Technology. The analysis was conducted through a survey utilizing questionnaire covering 5 Hypermarkets(Super-centers) including big 3 companies. Also, Japanese market trends have been studied to visit a Japan Government Organization concerned, GS1 Japan, an Agricultural Cooperative, an Agricultural Wholesale Market, and a Retail Company. If we could use KAN code for all agricultural products, we could collect and analyze the information of price and trade quantity of them. It opens a new era to understand the agricultural products supply and demand easily. This will certainly make a great contribution to the evolution of agricultural products distribution. From this research, it is suggested that collective efforts by suppliers, wholesalers, retailers and Government Officers are needed to make large scale mutual marketing Organizations, which specialize in sending out agricultural products. The Organization is recommended to standardize and pack every final agricultural products, to promote the use of KAN code.

β-catenin is a cytoplasmic protein that participates in the assembly of cell-cell adherens junctions by binding cadherins to the cytoskeleton. In addition, it is a key component of the Wnt signaling pathway. Activation of this pathway triggers the accumulation of β-catenin in the nucleus, where it activates the transcription of target genes. Abnarmal accumulation of β -catenin is characteristic of polyposis coli(APC) or Axin tumor suppressor proteins, which regulates β-catenin degradation, or activating mutations in β-catenin molecule itself. Here we show that overexpression of Sox4 down-regulates wild type β-catenin in HEK 293 cells. The inhibitory effect of Sox4 on wild type β-catenin is apparently mediated by the ubiquitin- proteasoem system and requires an active glycogen synthase kinase 3β(GSK3β). Mutations in the N-terminus of β -catenin(S33Y) which compromise its degradation by the proteasomes or inhibition of GSK3β activity rendered β-catenin resistant to down-regulation by Sox4. In light of recent evidence that Sox4 expression is activated in colon and other tumors with β-catenin dysregulation, our findings suggest that Sox4 is part of a feedback inhibitory pathway for Wnt signaling in normal cells. Moreover, the mutations in APC, Axin or β-catenin in cancer cells appear to render β-catenin resistant to the effects of Sox4 inhibition.

백침계 오이는 측지착과형으로 주지착과형인 국내용 오이와 차이가 있어 백침계 오이의 수량을 증가시키기 위해서는 측지발생을 높여야 가능하다. 그러나 백질계 오이의 재배시기는 대부분 동절기로 저온 및 일조부족 등의 불량한 환경조건 때문에 측지발생이 떨어진다. 본 연구는 생장조정제를 이용하여 백침계 오이의 측지발생을 촉진하기 위하여 BA의 농도 및 살포시기를 구명하고자 하였다 BA 30mg·L-1을 살포한 것은 농도 장해증상이 억제작형에서는 나타났으나, 반촉성작형에서는 경미하게 나타났다. 측지발생은 BA 10mg·L-1 살포하는 것이 BA 30mg·L-1 살포하는 것 보다 많았고, 처리시기는 본엽 10매, 15매 전개되었을 메 살포한 것이 본엽 5매 전개되었을 때 살포한 것보다 많았다.

우리의 식생활 및 주거 환경이 향상됨에 따라 과거에 비해 학생들의 체격이 커지고 체형 또한 점차 서구화 되가는 경향을 보이고 있으나 아직까지도 초·중·고등학교에서는 학생 자신의 체격에 적합하게 조절하여 사용할 수 없는 고정형 의자를 사용하고 있다. 이에 따라 학생들의 신체발육에 지장을 초래 할 수 있으며 특히 요통과 같은 허리에 문제를 일으킬 수 있다. 따라서 본 연구에서는 학생 자신의 체격에 맞게 높낮이를 자유롭게 조절하여

본 연구는 우리나라 국립공원의 대표적 자연해설시설인 탐방안내소 중 계획에 의해 조성ㆍ운영중인 내장산국립공원 내장사지구 탐방안내소와 북한산국립공원 정릉지구 탐방안내소를 대상으로 기능평가를 통한 이용활성화 방안제시를 목적으로 하였다. 국내외의 문헌연구를 통해 탐방안내소의 개념 및 기능, 유형 등을 파악하고 McManus의 커뮤니케이션 이론을 중심으로 탐방객에 의한 이용 후 평가를 실시하였다. 총 5단계에 걸친 평가 결과 탐방안내소 이용자들은 탐방안내소를 이해하기 위한 충분한 관람시간을 갖지 못하였으며 편의시설과 안내시스템의 부족으로 올바른 이용이 이루어지지 않았다. 전시내용에 대한 관람성향과 전시 내용의 이해도 부문 역시 전시물과 탐방객과의 원활한 커뮤니케이션이 이루어지고 있지 않음을 알 수 있었다. 이런 문제점들의 개선방안으로는 첫째, 탐방안내소 홍보 및 안내사인 보완 둘째, 다양한 계층을 고려한 전시관별 특성화와 차별화 된 전시연출 셋째, 각 전시내용들이 각 탐방객들의 사회적 경험과 연관되도록 하며 넷째, 전시주제에 맞는 전시매체의 적극적 활용이 필요함을 제안하였다.

This thesis investigates the feasibility and advantages of establishing a more efficient distribution system utilizing new technologies such as the internet and radio frequency identification (RFID). Introducing and promoting the diffusion of commodity traceability (the ability to trace the distribution route of products and materials) is necessary in order to make distribution and logistics more efficient, to clarify the safety of foods and daily necessities, to prevent theft and to monitor the dealing of stolen or imitation goods. This thesis focuses especially on a commodity (products) traceability system to enhance transparency for consumers. The expected effects of RFID can be summarized as follows. - Substantial improvement in logistics efficiency. - Higher consumer safety, quality management, and security for foods, drugs, and goods (clothes, books, electric appliances, automobiles, etc.) through improved traceability.