건축물에 가해지는 풍하중을 평가하는 방법은 과거로부터 많은 발전을 이루었다. 그 중 비교적 간단한 방법인 가스트하중계 수법이 있다. 정적풍하중에 동적계수를 곱하여 등가정적풍하중을 평가하는 방법으로 여러나라 기준에서 사용되고 있다. 동적계수는 가 스트영향계수(Gust Effect Factor:DGEF)와 가스트하중계수가(Gust Loading Factor:MGLF)가 사용된다. DGEF는 변위 기반으로서 이론 적인 가정을 통해 산출할 수 있는 반면 그 과정이 다소 복잡하고, MGLF는 모멘트를 기반으로 하며 풍동실험으로 전도모멘트를 측정 하여 산정할 수 있지만 기초자료를 구축하는 것에 많은 시간과 노력이 소요된다. 따라서 본 연구에서는 MGLF 산정 시 필요한 풍방향 평균풍력계수C F, 평균전도모멘트계수C M, 변동전도모멘트계수 C M 가 다양한 형상비( ), 변장비(D/B), 지표면조도구분(α)에 따 라 변화하는 경향을 비교 분석하였다. 이를 통해 풍방향 평균풍력계수 C F, 평균전도모멘트 관련 계수 C g, 변동전도모멘트 관련 계수 C g 의 경험식을 제안하여 MGLF 산정에 대한 기초자료를 제시하였다.

Functional dyspepsia (FD) is a gastrointestinal disorder with diverse symptoms but no structural or organic manifestations. Benachio-F® (herein named ‘BF-1’) is an over-the-counter liquid digestive formulated with multiple herbal extracts, which has been reported to improve symptoms of FD. A total two experiments were conducted. First, we examined whether BF-1 can modulate the progression of FD through two experimental rat models. A total of three doses (0.3x, 1x, 3x of the human equivalent dose) were used. In the gastric emptying model, both 1x (standard) or 3x (3-fold-concentrated) BF-1 enhanced gastric emptying was compared with that of vehicle-treated animals. In a feeding inhibition model induced by acute restraint stress, treatment with 1x or 3x BF-1 led to a similar degree of restoration in food intake that was comparable to that of acotiamide-treated animals. Among the constituents of BF, fennel is known for its choleretic effect. Thus, we next investigated whether a novel BF-based formula (named ‘BF-2’) that contains an increased amount of fennel extract (3.5-fold over BF-1), has greater potency in increasing bile flow. BF-2 showed a superior choleretic effect compared to BF-1. Furthermore, the postprandial concentration of serum secretin was higher in animals pretreated with BF-2 than in those pretreated with BF-1, suggesting that the increased choleretic effect of BF-2 is related to secretin production. Our results demonstrate that BF-1 can modulate the pathophysiological mechanisms of FD by exerting prokinetic and stress-relieving effects, and that BF-2 has a better choleretic effect than BF-1.

최근 친환경, 신재생 에너지 수요에 따라서 해상풍력발전 분야는 빠른 성장세와 설비의 대형화에 따른 전용설치선박의 관련 기술개발이 요구되고 있다. 해상풍력설치선박(WTIV: Wind Turbine Installation Vessel)은 설치 작업 시 선체를 파도의 영향을 받지 않는 높이로 이동시키고 모든 환경하중은 레그가 담당한다. 특히 파랑하중은 불규칙파로 구성되어 있기 때문에, 정확한 동적응답특성을 파악하는 것은 아주 중요한 문제이다. 이러한 동적응답해석은 간이법의 하나인 단자유도법을 널리 활용하고 있으나, 불규칙 파를 고려 하지 못하는 제약조건이 있다. 따라서 현재 설계 시 불규칙 파에 대한 시간영역 계산이 가능한 다자유도 계산법을 사용하고 있다. 그 러나 다자유도 계산법에서 시간영역 해석은 정도 높은 계산 결과를 제공하지만, 데이터의 수렴도가 민감하고 복잡성에 있어 설계 시 어려움이 있다. 따라서 본 논문은 다양한 변수를 기준으로 한 시간영역 해석을 통하여 불규칙 파의 동적응답 특성을 표현 할 수 있는 동적증폭계수 추정식을 개발하였다. 기존 다자유도 모델 대비 계산시간 단축 및 정확도 확보를 확인하였다. 개발된 동적증폭계수 추정식은 WTIV 및 유사 구조물 설계에 활용이 가능할 것으로 판단된다.

Methods for predicting the ultimate/buckling strength of ship structures have been extensively improved in terms of design formulas and analytical solutions. In recent years, the design strategy of ships and offshore structures has tended to emphasize lighter builds and improve operational safety. Therefore, the corresponding geometrical changes in design necessitate the use of high-tensile steel and thin plates. However, the existing design formulas were mainly developed for thick plates and mild steels. Therefore, the calculation methods require appropriate modification for new designs beased on high-tensile steel and thin plates. In this study, a modified formula was developed to predict the ultimate strength of thin steel plates subjected to compressive and shear loads. Based on the numerical results, the effects of the yield stress, slenderness ratio, and loading condition on the buckling/ultimate strength of steel plates were examined, and a newly modified double-beta parameter formula was developed. The results were used to derive and modify existing closed-form expressions and empirical formulas to predict the ultimate strength of thin-walled steel structures.

본 연구는 조제유류 중 지방산에 대해 최신 분석법을 마련하고자 수행하였다. 조제유류 중 지방산 함량 분석을 위해 GC를 이용한 분석법을 확립하고 시중에 유통 중인 제품을 대상으로 적용성을 검토하였다. 분석법 검증은 특이성, 직선성, 검출한계 및 정량한계, 정확성, 정밀성에 대해 수행되었다. Linoleic acid 및 α-linolenic acid의 0.1-5 mg/ mL 농도범위에서 R2=0.999 이상의 우수한 직선성을 확인할 수 있었다. Linoleic acid 및 α-linolenic acid의 LOD는 각각 0.06 mg/mL, 0.01 mg/mL, LOQ는 각각 0.16 mg/mL, 0.03 mg/mL였다. 표준인증물질 분석을 통해 정확성을 검토 하였으며, linoleic acid 및 α-linolenic acid의 회수율은 각각 100.8%와 101.1%로 확인하였다. 정밀성을 검토한 결과 시료 채취량에 따른 반복성은 linoleic acid 1.4-2.9%, α- linolenic acid 1.1-2.7%이었고, 실험실간 재현성은 각각 2.8%, 1.5%임을 확인하였다. 본 연구에서 확립된 분석법을 적용하여 국내 유통 중인 조제유류 및 조제식 제품 12건에 대해 적용성 검토를 실시한 결과 전체 시료에서 분석이 용이 하였으며, 모두 기준·규격에 적합함을 확인하였다. 본 결과로부터 확립된 GC를 이용한 분석법은 조제유류 중 지방산 함량을 확인하기에 적합함을 확인하였으며 국내 식품 영양 성분의 관리 기반을 강화하는데 기여할 것으로 사료된다.

School of Chinese Medicine, Beijing University of Chinese Medicine Objective: To trace the origin and development of medicinal tea formulas, explores the medicinal value of tea in the formulas to provide traditional Chinese medicine practitioners with the idea of using tea in the formulas. Methods: This thesis combed through the medicinal tea formulas in the medical books of the past dynasties and explored the main indication, usage and preparation of the medicinal tea formulas. Results: Tea had the record with the medicinal effects in many herbal literatures. Doctors often used tea with other Chinese herbs together in the formulas. Conclusion: This kind of formula combining tea and Chinese herbs was called as “medicinal tea formula”. Medicinal tea formula had been standardized and formed during the Song Dynasty in China. A comprehensive overview of the medicinal tea formulas from the Tang Dynasty to the Qing Dynasty can provide a reference for the treatment of many indications and improve the value of the medicinal tea formulas.

PURPOSES : For the compaction control on the subgrade layer, dynamic cone penetration test (DCPT) is being applied to the Korea pavement subgrade construction guidelines. The existing equation in the Korean guidelines for estimating the resilient modulus, MR, from the DCPT test result penetration rate (PR), is a correlation developed from a small amount of data and does not consider the degree of compression. Therefore, this study attempts to propose an advanced MR-DCPT PR correlation through the correction of existing data and additional field tests. METHODS : The in-situ DCPT tests were conducted according to the types of subgrade soils in the field. Thereafter, the existing guideline‘s data were collected and corrected with the degree of compaction, R. RESULTS : In this study, the correlation coefficient is improved such that it is considerably higher than the existing equation using additional field data and converting the data used in the existing equation into data with over 95% degree of compaction. CONCLUSIONS : Through verification, it was found that the relative errors of the proposed correlations in this study were reduced when compared with the existing equation.

The diesel engine is excellent in economic and thermal efficiency, and is widely used as a power source for industries and automobiles. However, the problem of environmental pollution caused by exhaust gas has recently become serious and the development of alternative energy resources is urgently required due to depletion of fossil fuel. Because biodiesel is similar in properties to light oil, it is being used as fuel for diesel engines by replacing or mixing conventional light oil. As the blending of biodiesel fuel in diesel increases, the emission of harmful substances is decreased as compared with the general diesel fuel, and the supply is increasing. In this study, the effects of biodiesel fuel on engine power and exhaust gas were investigated, and empirical formulas for various NOx and Smoke exhaust gases were derived based on biodiesel blending fuel.

As buildings are becoming larger, demand for mega-sized composite columns (over 1-meter diameter) is increased. We have developed and commercialized welded built-up CFT column (ACT Column I) since 2005 which are structurally stable and economical using cold-formed steel with rib. However, there has a limit in size of cross section (618˟618mm) by a fabrication facilities. And due to characteristics of closed cross section, there has a limit to construction of connection of moment frame. Composite mega column (ACT Column II) has same concept of forming closed cross section. But in order to enlarge cross sectional size, thick plate is inserted between cold-formed steels. Since composite mega column can control thickness and width of thick plate, steel or composite beams can be directly attached to the connection. In this study, we propose strength formula of composite mega column to beam connections with T-shaped stiffener as internal diaphragm and verified through finite element analysis and simple tensile experiment.

In this study, natural period formular is presented for a RC shear wall structure with H-, T-, and L-shaped wall sections. The natural period formular proposed by Goel and Chopra and adopted in ASCE 7-10 was modified by using the ratio of the flange and web wall area. The natural periods of structures with H-shaped wall were numerically obtained, the results indicated that the ASCE 7-10 could not consider the natural period variation according to the length of the flange wall, but the proposed formula could do. Especially, ASCE 7-10 estimated much longer periods than eigenvalue analysis, and this implies that conservative seismic design is difficult. The periods by eigenvalue analysis exist between the upper and lower bounds given by the proposed formula, and conservative design is possible by using the proposed lower bound value. In order to verity the effectiveness of the proposed method, actual residential buildings with various types of flange walls are considered. Ambient vibration tests, eigenvalue analyses, and nonlinear dynamic analyses were conducted and the periods were compared with the values by ASCE 7-10 and the proposed formula. The results showed that the proposed formula could estimate more accurately the periods than ASCE 7-10.

Purple-fleshed potato powder (PFPP) was investigated to determine optimal mixing ratio with milk powder and dextrin to produce a ready-to-eat mashed potato powder. The rheological characteristics, color, and anthocyanin contents were studied at a different concentration of ingredients. The power-law model was applied to explain the mechanical spectra of mashed potatoes which represented the change in structure induced by different mixing ratios. Mixture design was used to obtain the experimental points used to establish the empirical models to describe the effects of each ingredient on the characteristic of the mashed potato. The results of mechanical spectra showed that both storage and loss moduli (G' and G'') were significantly influenced by PFPP and milk powder concentration. The power law parameters n' and n'' showed higher values for the mashed potato with a lower concentration of PFPP and a higher concentration of milk powder, which showed that the gel networks involved in the mashed potato were weaker. The optimum mixing ratio with the highest redness and anthocyanin content, while maintaining the rheological properties similar to the commercial mashed potato, was determined as PFPP:milk powder:dextrin = 90.49:4.86:4.65 (w/w). The proportions of PFPP and milk powder in the formulation significantly changed the characteristics of mashed potato, whereas no significant effect of dextrin was observed in this formulation.

Purple-fleshed potato powder (PFPP) was investigated to determine optimal mixing ratio with milk powder and dextrin to produce a ready-to-eat mashed potato powder. The rheological characteristics, color, and anthocyanin contents were studied at a different concentration of ingredients. The power-law model was applied to explain the mechanical spectra of mashed potatoes which represented the change in structure induced by different mixing ratios. Mixture design was used to obtain the experimental points used to establish the empirical models to describe the effects of each ingredient on the characteristic of the mashed potato. The results of mechanical spectra showed that both storage and loss moduli (G' and G'') were significantly influenced by PFPP and milk powder concentration. The power law parameters n' and n'' showed higher values for the mashed potato with a lower concentration of PFPP and a higher concentration of milk powder, which showed that the gel networks involved in the mashed potato were weaker. The optimum mixing ratio with the highest redness and anthocyanin content, while maintaining the rheological properties similar to the commercial mashed potato, was determined as PFPP:milk powder:dextrin = 90.49:4.86:4.65 (w/w). The proportions of PFPP and milk powder in the formulation significantly changed the characteristics of mashed potato, whereas no significant effect of dextrin was observed in this formulation.

Cylindrical shells are often used in ship structures at deck plating with a camber, side shell plating at fore and aft parts, and bilge structure part. It has been believed that such curved shells can be modelled fundamentally by a part of a cylinder under axial compression. From the estimations with the usage of cylinder models, it is known that, in general, curvature increases the buckling strength of a curved shell subjected to axial compression, and that curvature is also expected to increase the ultimate strength. We conduct series of elasto-plastic large deflection analyses in order to clarify the fundamentals in buckling and plastic collapse behaviour of cylindrical shells under axial compression. From the numerical results, we derive design formula for predicting the ultimate strength of cylindrical shell, based on a series of the nonlinear finite element calculations for all edges, simply supporting plating, varying the slenderness ratio, curvature and aspect ratio, as well as the following design formulae for predicting the ultimate strength of cylindrical shell. From a number of analysis results, fitting curve can be developed to use parameter of slenderness ratio with implementation of the method of least squares. The accuracy of design formulae for evaluating ultimate strength has been confirmed by comparing the calculated results with the FE-analysis results and it has a good agreement to predict their ultimate strength.

All elements evolution of Chinese was very intensive from Han to Tang dynasty. The interruptive interrelationship about the shapes, sounds and semantics of Chinese language and characters could be reconnected through the social material object. Stone inscriptions about ancient China are valuable material for the study of language and culture. Basing on a large amount of stone inscriptions from Han to Tang dynasty, this paper straightened out the development and evolution of “Qu” (去) as preposition in ancient China. We discussed Writing style reflected in epitaphs and the avoidance of word‟s repetition in stone inscription.

두 종류의 Cronobacter 선택배지(DFI agar, R&F agar) 의 분유 및 건조호박 내 Cronobacter의 선택 분리능을 realtime PCR법과 함께 비교하였다. 분유에서의 Cronobacter 검출률은 세 가지 방법에서 유의적인 차이를 나타내지 않았으나(p < 0.05), 건조호박의 경우 R&F배지와 real-time PCR법이 DFI에서보다 유의적으로 높은 검출률을 보였다 (p < 0.05). 배지 간 선택성에 있어서도, R&F 선택배지는 건조호박에서 DFI에 비해 유의적으로 높은 선택성을 나타냈다(p < 0.05). Real-time PCR 및 R&F배지의 사용은 분유뿐만 아니라, 건조 호박 등의 높은 경쟁세균총을 갖는 영유아식의 원료로 사용될 수 있는 식품군에서도 Cronobacter를 효과적으로 검출할 수 있는 방법으로 사료된다.

Choline is an amine essential to maintenance of good health. Here, we modified the ion chromatographic method for measuring choline described by Laikhtman & Rohrer and validated by the ICH guideline and applied it to monitoring of choline content in infant formula in the Republic of Korea. The Certified Reference Materials (CRM), NIST 1849a, were used for validation of the modified method. The parameters of validation were linearity, range, specificity, accuracy, precision, LOD, LOQ and recovery. The linearity, R2, was above 0.999 and the analytical range was 2.5 to 50 μg/mL. The specificity was confirmed by the retention time (RT) and positive tests with calibration standard and CRM. The accuracy, precision and recovery values were 99.6 ± 2.41 %, 2.42 % and 90.8 - 92.8 %. The LOD and LOQ values were 0.03 mg/kg and 0.17 mg/kg, respectively. Five livestock products inspection agencies voluntarily participated in the collaborative study. The result, HORRAT value was 0.8 which was within the reference value 0.5 – 2.0. The validated method was applied to the analysis of choline in infant formula in the Republic of Korea. The results also conformed to 'The Standard for Livestock Products Labeling'.