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        검색결과 362

        1.
        2023.12 KCI 등재 구독 인증기관 무료, 개인회원 유료
        본 연구는 PEBAX/PVDF 복합막을 제조하고 에탄올/물 혼합액에 대한 투과증발 성능을 평가하였다. 또한 PVDF 지지체 표면에 ZIF-8 층을 형성하여 복합막의 투과증발 성능을 향상시키고자 하였고, PEBAX 선택층 두께에 따른 성능 비교 를 통해 최적의 막을 선정하였다. 제작된 복합막을 물과 에탄올이 95/5 중량비로 혼합된 공급액에 대하여 투과증발 실험을 수행하였다. 그 결과 ZIF-8 충이 형성된 PVDF 지지체를 사용한 복합막의 경우 플럭스 1.98 kg/m2h, 분리 계수 3.88로 일반 PVDF 지지체를 사용한 복합막보다 투과량과 선택도가 모두 높은 값을 나타내었다.
        4,000원
        4.
        2023.10 구독 인증기관·개인회원 무료
        Golden apple snails(GAS) are native to warm regions such as Central and South America and Southeast Asia, and were first introduced as a high-protein food. GAS are omnivorous and have a habit of eating plants submerged in water, so they have been used for eco-friendly weed control in rice fields since 1992. When the GAS was first introduced, it was thought that it would be impossible to overwinter in Korea. However after 2000, overwintering individuals were founded and damage to rice occurred and the development of means to control GAS has been required. In this study, we tested the effectiveness of an eco-friendly pest control agent using Styrax japonicus that grow naturally in Korea. As a result of exposing GAS to S. japonicus fruit powder, a 100% molluscicidal effect was confirmed at 66.7ppm. To investigate the duration of effect, treatment was performed at the same concentration and molluscicidal effect of more than 90% was up to 3 days after treatment. The killing effect of each part of the S. japonicus was compared, and the seed extracts showed no killing effect at all concentrations, while the sarcocarp extracts showed a 100% killing effect up to 33.3ppm, and the fruit extracts showed a 100% killing effect up to 200ppm.
        5.
        2023.08 KCI 등재 구독 인증기관 무료, 개인회원 유료
        This study investigated the anti-obesity effects of Coriandrum sativum L. ethanol extracts in a high fat diet-induced obesity model (DIO). We confirmed the anti-obesity effects by analysing the expression of the related proteins, weight gain, dietary intake, dietary efficiency, blood biochemistry, histological analysis and western blot analysis. After oral administration of Coriandrum sativum L. ethanol extracts at concentrations of 250 and 500 mg/kg, a significant improvement in dietary efficiency, reduction in weight gain, triglycerides, total cholesterol and LDL-cholesterol in blood lipid was observed for 8 weeks. In addition, improvement in blood glucose and metabolism confirmed through glucose tolerance test was observed. Further, the concentration of alanine transaminase (ALT) in blood was significantly decreased, which improved the fatty liver caused by high-fat diet intake as confirmed by liver tissue analysis. This phenomenon was confirmed to decrease the expression of fat accumulation-related PPARγ and FAS protein in the liver tissue. Especially, it is believed that FAS, a liposynthetic enzyme, has a stronger inhibitory effect than PPARγ. Therefore, Coriandrum sativum L. ethanol extract is thought to improve obesity by reducing blood lipids levels, improving glucose metabolism and inhibiting synthesis of the fat that accumulates in the liver in high-fat diet-induced obesity animal models.
        4,500원
        6.
        2023.08 KCI 등재 구독 인증기관 무료, 개인회원 유료
        ‘갑주백목’ (Diospyros kaki Thunb cv. Hachiya) 감은 현재 홍시 또는 건시로만 식용되고 있는데 탈삽된 생과로서의 활용이 기대된다. CO2 및 ethanol 탈삽 처리와 동시에 1-methylcyclopropene (1-MCP)를 처리하여 탈삽과 연화억제에 대한 효과를 보고자 본 연구를 수행하였다. CO2 탈삽은 20L 아크릴 용기를 이용하여 95% CO2를 24시간, ethanol 탈삽은 PE 필름(85.0cm×63.5cm)을 이용하여 99.9% ethanol 20ml를 3일간 상온(23℃)에서 처리하였다. 1-MCP는 탈삽 처리와 동시에 1μL・L-1을 처리하였다. 탈삽 처리 후 상온 모의유통과 3주 저온저장 후 상온 모의유통의 두 가지 조건에서 과실의 품질을 조사하였다. CO2는 처리 종료 후 2일에 ethanol은 5일에 식용이 가능한 상태로 탈삽 되었으며 탈삽이 완료되지 않은 과실은 3주간의 저온 저장에서 완전히 탈삽되었다. 1-MCP는 탈삽속도에는 큰 영향을 미치지 않았으며 CO2와 ethanol 탈삽 모두에서 우수한 연화억제 효과를 나타내었다. 특히, 3주 저온 저장 후 상온 유통에서 1-MCP의 연화억제 효과는 더욱 크게 나타났다. 이상의 결과로 볼 때 1-MCP는 감의 탈삽에 있어 별도의 처리시간을 필요로 하지 않는 효과적인 연화억제 수단으로 판단되며, 이러한 ‘갑주백목’ 탈삽 생과는 향후 국내 유통 및 해외 수출이 기대된다.
        4,000원
        9.
        2023.02 KCI 등재 구독 인증기관 무료, 개인회원 유료
        To apply UV-C as a non-heating sterilization method to increase the microbiological safety of fresh seedless watermelon products, reductions in E. coli and quality changes by treatment dose (0, 2, 4, 8, 14, 20 kJ/m2) were investigated. The pH, sugar content, and hardness of watermelon inoculated with E. coli were not significantly different according to the UV-C treatment dose, but the polyphenol content was significantly decreased compared to the controls (425.4 GAE μg/g F.W.). When treated with 2 and 4 kJ/m2, the lycopene content was 31.6 and 30.9 μg/g F.W., respectively, which was increased compared to the controls (28.5 μg/g F.W.). The arginine and citrulline content was also significantly increased compared to the controls. The number of E. coli was significantly decreased compared to the controls following UV-C treatment. Considering the degree of E. coli reduction, lycopene content, arginine content, citrulline content, and UV-C irradiation time, subsequent experiments were conducted by selecting a UV-C treatment dose of 2 kJ/m2. The results of confirming the degree of reduction in the number of E. coli colonies by a single treatment and combined treatment with UV-C 2 kJ/m2 and 70% ethanol showed that the combined treatment was most effective as colonies were decreased by 2.3 log CFU/g compared to the controls. Therefore, it is judged that UV-C 2 kJ/m2 radiation and combined treatment with 70% ethanol could be applied as a non-heating sterilization method for fresh watermelon slices.
        4,000원
        11.
        2022.10 구독 인증기관·개인회원 무료
        Radioactive contamination of soil on the site of a nuclear facility has a characteristic that radioactive nuclides are adsorbed into the pores between soil particles, making it quite difficult to decontaminate. For this reason, research on the development of various decontamination processes is being actively conducted. In this study, among various decontamination studies, a soil decontamination process using supercritical carbon dioxide was presented. The decontamination process uses supercritical carbon dioxide as the main solvent, which has a higher penetration power than other materials. Therefore, the process consists of the process of desorbing and extracting the target radionuclides between particles of soil. However, since nuclides exist as ions in the soil, polar chelating ligand material was introduced as an additive to nonpolar supercritical carbon dioxide for smooth chemical reactions in the soil. Thereafter, from the viewpoint of improving process continuity and efficiency, an alcohol material was introduced as an auxiliary solvent for liquefaction of chelating ligand in a solid state. Through prior research on the selection of a solvent for liquefaction of chelating ligand, ethanol and 2-propanol were finally selected based on whether the chelating ligand was dissolved. However, if the auxiliary solvent in which the chelating ligand is dissolved is to be combined with radionuclides in the soil, it must first be well dissolved in supercritical carbon dioxide, the main solvent. Therefore, in this study, the solubility of ethanol and 2-propanol in supercritical carbon dioxide was measured and the suitability was evaluated. The temperature conditions were carried out at 40°C, the same as the previously designed decontamination process, and the measurement was conducted by adjusting the pressure and volume through a syringe pump and a variable volume device. In addition, solubility was measured based on the observation of the ‘cloud point’ in which the image becomes cloudy and then bright. As a result of the experiment, several solubility points were measured at a pressure of 150 bar or less. If the flow rate ratio of supercritical carbon dioxide and auxiliary solvent derived from the results is applied to the soil decontamination process, it is expected that the process efficiency will increase in the future.
        12.
        2022.10 구독 인증기관·개인회원 무료
        Korea faces decommissioning the nation’s first commercial nuclear power plant, the Kori-1 and Wolseong-1 reactors. In addition, other nuclear power plants that will continue to operate will also face decommissioning over time, so it is essential to develop independent nuclear facility decommissioning and site remediation technologies. Among these various technologies, soil decontamination is an essential not only in the site remediation after the decommissioning of the highly radioactive nuclear facility, but also in the case of site contamination caused by an accident during operation of the nuclear facility. But the soil, which is a porous material, is difficult to decontaminate because radionuclides are adsorbed into the pores. Therefore, with the current decontamination technology, it is difficult to achieve the two goals of high decontamination efficiency and secondary waste reduction at the same time. In this study, a soil decontamination process with supercritical carbon dioxide as the main solvent was presented, which has better permeability than other solvents and is easy to maintain critical conditions and change physical properties. Through prior research, a polar chelating ligand was introduced as an additive for smooth extraction reaction between radionuclides present as ions in soil and nonpolar supercritical carbon dioxide. In addition, for the purpose of continuity of the process, a candidate group of auxiliary solvents capable of liquefying the ligand was selected. In this research evaluated the decontamination efficiency by adding the selected auxiliary solvent candidates to the supercritical carbon dioxide decontamination process, and ethanol with the best characteristics was selected as the final auxiliary solvent. In addition, based on the decontamination effect under a single condition of the auxiliary solvent found in the Blank Test process, the possibility of a pre-treatment leaching process using alcohol was tested in addition to the decontamination process using supercritical carbon dioxide. Finally, in addition to the existing Cs and Sr, the possibility of decontamination process was tested by adding U nuclides as a source of contamination. As a result of this research, it is expected that by minimizing secondary waste after the process, waste treatment cost could be reduced and the environmental aspect could be contributed, and a virtuous cycle structure could be established through reuse of the separated carbon dioxide solvent. In addition, adding its own extraction capacity of ethanol used for liquefaction of solid-phase ligands is expected to maximize decontamination efficiency in the process of increasing the size of the process in the future.
        13.
        2022.06 KCI 등재 구독 인증기관 무료, 개인회원 유료
        Aralia elata, Chaenomeles sinensis fruit, and Glycyrrhizae radix have been widely used as oriental medicinal plants in Korea, China and Japan and found to possess anti-oxidative and anti-inflammatory activities. The current study was conducted to investigate the neuroprotective effect of an ethanol extract of a mixture of A. elata, C. sinensis fruit, and Glycyrrhizae radix (ACG) against ischemia-induced brain injury in rats and excitotoxic and oxidative neuronal death in primarily cultured rat cortical neurons. Transient focal cerebral ischemia was induced by 2 h middle cerebral artery occlusion followed by 24 h reperfusion (MCAO/R) in rats. Oral administration of ACG (10, 25, and 50 mg/kg) 30 min before MCAO, after 1 h of MCAO, and after 1 h of reperfusion reduced MCAO/R-induced brain infarct and edema formation. ACG also inhibited development of behavioral disabilities in MCAO/R-treated rats. Exposure of cultured cortical neurons to 500 μM glutamate for 12 h resulted in neuronal cell death. ACG (1, 10, and 50 μg/mL) inhibited glutamate-induced neuronal death. Furthermore, ACG inhibited 100 μM hydrogen peroxide (H2O2)- and hypoxia-induced neuronal death. These results suggest that the neuroprotective effect of ACG against ischemia-induced brain damage might be associated with its anti-excitotoxic and anti-oxidative activity and that ACG may have a therapeutic role for prevention of neurodegeneration in stroke.
        4,200원
        14.
        2022.04 KCI 등재 구독 인증기관 무료, 개인회원 유료
        알코올의 탈수를 위하여 에너지 다소비 공정인 증류 공정을 투과증발 막 공정으로 대체하려는 연구가 많이 진행 되어져 왔다. 대표적인 투과증발 막인 PDMS 분리막에 대한 시간의존적 분리 거동은 분리 메카니즘의 이해에 매우 중요하다. 따라서 본 연구에서는 50 wt% 에탄올-물 혼합용액에 대하여 50°C에서 막면적 1194 cm2인 PDMS/PSF 분리막 모듈의 시간의 존적인 투과증발 분리 거동을 고찰하였다. 총 유속과 에탄올/물 분리계수는 투과증발 시간이 증가함에 따라서 초기에 증가하 다가 다시 감소하였다. 초기 분리성능의 증가는 건조한 PDMS 분리막에 에탄올이 용해되는데 시간이 걸리기 때문이며, 후기 분리성능의 감소는 주입 탱크의 에탄올 농도가 시간에 따라서 감소하기 때문에 나타나는 현상이었다. 따라서 본 연구로부터 PDMS 분리막을 통한 에탄올의 투과는 용해-확산 메카니즘에 의해 발생된다는 것이 재확인되었다.
        4,000원
        17.
        2022.03 KCI 등재 구독 인증기관 무료, 개인회원 유료
        Toxoplasmosis, caused by Toxoplasma gondii (Tg), is one of the most prevalent zoonotic diseases worldwide. Currently, safe and efficient therapeutic options for this disease are still being developed, and are urgently needed. Agrimonia pilosa (A. pilosa) is a rosaceous plant, and widely distributed in Asia. The bioactive compounds in A. pilosa Ledeb include flavonoid, triterpenoids, and isocoumarin, and have been reported to show many pharmacological effects including anti-inflammatory, antioxidant, and antibacterial activities.The aim of this study was to determine Anti-protozoal efficacy of Agrimonia pilosa ethanol extract (APE) against Toxoplasma gondii (Tg). In this study, APE was examined and screened for anti-Tg activity. Seventy percent ethanol was used for herbal extraction. For anti-Tg activity screening, in vitro study with APE using tachyzoit of Tg RH strain infected HeLa cells were performed. Also, in vivo anti- Tg study using the mouse infection model was conducted. As the results, the selectivity of APE was 3.35, which was higher than Sulfadiazine selectivity (2.08). Also, we performed in vivo animal study to evaluate the anti-Tg activity of APE with mouse model. As the results, Anti-toxoplasma activity of the APE was as high as sulfadiazine. These results demonstrate that it can be successfully cured against Tg infection with APE. It could be a promising native herb treatment for the prevention of Tg infection.
        3,000원
        18.
        2022.03 KCI 등재 구독 인증기관 무료, 개인회원 유료
        A novel brown rot fungus Phaeolus schweinitzii IUM 5048 was firstly used for ethanol production. It was found that this fungus produced ethanol with various sugars, such as glucose, mannose, galactose and cellobiose at 0.28, 0.22, 0.06, and 0.22 g of ethanol per g of sugar consumed, respectively. This fungus showed relatively good ethanol production from xylose at 0.23 g of ethanol per g of sugar consumed. However, the ethanol conversion rate of arabinose was relatively low (at 0.08 g of ethanol per g sugar). P. schweinitzii was capable of producing ethanol directly from rice straw and corn stalks at 0.11 g and 0.13 g of ethanol per g of substrates, respectively, when the fungus was cultured in a basal medium supplemented with 20 g/L rice straw or corn stalks. These results suggest that P. schweinitzii can hydrolyze cellulose or hemicellulose to fermentable sugars and convert them to ethanol simultaneously under oxygen limited condition
        4,000원
        19.
        2022.02 KCI 등재 구독 인증기관 무료, 개인회원 유료
        This study evaluates the gastroprotective effect of cabbage extract with sulforaphane content of 5.19 mg/L and Smethylmethionine content of 469.28 μg/L. In vitro, the lipopolysaccharide (LPS)-treated group had an increased NO activity compared to the normal group, and the concentration of NO was reduced when the cabbage extract was treated in the dose manner. The level of IL-6 induced by LPS was dose-dependently reduced when the extract was treated. The cabbage extract concentration was orally administered in rats at 5.75 mg/kg, 11.5 mg/kg, and 23 mg/ kg, and the inhibitory effect on gastric damage by HCl-ethanol was observed. Histological analysis exhibited mucosal erosion in the gastritis model compared to the normal group, while the ameliorating effect of the generated erosion was observed in the cabbage-treated group. The histamine concentration was significantly increased in the gastritis-induced animal model, and the histamine concentration was decreased in the 23 mg/L-treated group of cabbage extract. In conclusion, the results of this study suggest that cabbage extract not only down-regulates cytokines in vitro, but is also directly involved in histamine secretion in an animal model of gastritis; therefore, cabbage extract can help inhibit gastrointestinal disorders by improving the protective barrier.
        4,000원
        20.
        2021.12 KCI 등재 구독 인증기관 무료, 개인회원 유료
        The fruit stalk of Hovenia dulcis (H.dulcis) is traditionally used to relieve hangovers in Korea. Theracurmin is a highly absorbable curcumin preparation which increases the bioavailability of curcumin. Curcumin is known for its antioxidant and anti-inflammatory effects. However, the role of this combination in lowering alcohol levels in the body, thereby alleviating the severity of alcohol-induced hangover has not been investigated. Therefore, we conducted a study to investigate the eliminatory effects of a health drink containing the extract of the H. dulcis fruit stalk and theracurmin (theracurmin drink) on ethanol-induced hangover in rats. The theracurmin drink delivered orally to rats 30 mins before the administration of 40% ethanol (5 g/kg body weight), lowered the concentration of ethanol and acetaldehyde in the blood samples collected 1, 3, and 5 h after ethanol administration. Furthermore, the theracurmin drink increased the activities of alcohol dehydrogenase and aldehyde dehydrogenase enzymes. The effectiveness of the theracurmin drink was thus superior to that of other health drink products, suggesting that its consumption may alleviate or prevent an alcohol-induced hangover.
        4,000원
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