지표성 곤충 군집은 환경 변화에 민감하게 반응하여 산림 생태계 변화를 이해하는 중요한 생물학적 지표로 활용된다. 본 연구는 광릉숲 조림지 내 장기적인 생태적 천이 과정에서 지표성 곤충 군집의 다양성과 기능 형질이 어떻게 변화하는지 파악하고자 하였다. 조사는 2019년, 2021년, 2023 년 총 3회에 걸쳐 함정 트랩을 이용하여 이루어졌으며, 채집된 곤충의 군집 다양성과 먹이생태지위, 서식지 유형, 크기, 섭식 유형 등 4개의 기능 형 질을 분석하였다. 조사 결과, 총 6목 27과 94종 1,442개체가 채집되었으며, 연도가 지남에 따라 풍부도, 심슨 지수, 다양도 지수, 균등도가 모두 유의 미하게 증가하였다. 우점종은 2019년 둥근칠납작먼지벌레(Synuchus arcuaticollis), 2021년 일본장다리개미(Aphaenogaster japonica), 2023년 장 수땅노린재(Adrisa magna)로 매년 다르게 나타났다. 기능 형질 변화의 경우, 먹이생태지위와 섭식 유형은 뚜렷한 변동성을 보인 반면, 크기와 서식 지 유형은 점진적인 변화를 보였다. 곤충 군집 구조는 연도에 따라 뚜렷한 차이를 보이며, 이러한 변화는 토양 노출도, 목질 잔해물, 하층식생 피도와 유의한 상관관계를 나타냈다. 본 연구를 통해 지표성 곤충 군집의 구조뿐만 아니라 기능 또한 변화하고 있음을 확인하였으며, 이러한 변화가 환경 요인과 밀접한 관련이 있음을 알 수 있었다. 이는 산림 복원 과정의 생태적 천이 모니터링과 생물다양성 보전 전략 수립에 유용한 기초 자료를 제공 한다.

Background: Lumbar radiculopathy caused by disc herniation is frequently accompanied by pain, functional disability, and impairments in sensorimotor control, including reduced proprioception and altered motor control. Interventions that integrate neural and mechanical components may enhance rehabilitation outcomes beyond exercise alone. Objectives: To investigate the effects of manual therapy combined with neurodynamic exercise and motor control exercise (MTN) with motor control exercise alone (MCE) on lumbar proprioception, motor control, and functional disability in patients with lumbar radiculopathy. Design: Randomized, single-blind clinical trial. Methods: Thirty patients with lumbar radiculopathy due to L4–S1 disc herniation were randomly assigned to either the MTN group or the MCE group. Both groups participated in supervised interventions three times per week for six weeks. The MTN group received lumbar joint mobilization and slider-based neurodynamic mobilization integrated with motor control exercise, whereas the MCE group performed motor control exercise only. Lumbar proprioception was assessed using joint position error during trunk flexion and extension. Motor control was evaluated using pressure biofeedback–based abdominal drawing- in performance. Functional disability was assessed using the Korean version of the Oswestry Disability Index. Outcomes were measured at baseline and during follow-up. Results: Significant group-by-time effects were observed for lumbar joint position error, motor control outcomes, and functional disability. The MTN group demonstrated earlier and greater improvements across all outcome measures compared with the MCE group, whereas improvements in the MCE group were more gradual. Conclusion: Compared with motor control exercise alone, the addition of manual therapy and neurodynamic exercise resulted in superior improvements in lumbar proprioception, motor control, and functional disability. An integrated MTN approach may be an effective rehabilitation strategy for patients with lumbar radiculopathy.

Background: Despite various treatment methods, many functional ankle instability (FAI) patients continue to experience functional deficits. Objectives: To investigate the effect of additional auditory feedback on balance and ankle function in task-oriented balance training for FAI patients. Design: Randomized controlled trial design. Methods: Forty FAI patients were randomly assigned to the auditory feedback task-oriented balance training (ATBT) group (n=20) and the task-oriented balance training (TBT) group (n=20). The training program was implemented for 4 weeks, 3 days a week. Results: After training, the COG movement area, speed, and distance significantly decreased in both the ATBT and TBT groups (P<.05). Additionally, the COG movement speed and distance in the ATBT group were significantly decreased compared to the TBT group (P<.05). The 6-meter crossover hop test time decreased in both the ATBT and TBT groups (P<.05). The ATBT group exhibited a significantly decreased 6-meter crossover hop test time compared to the TBT group (P<.05). Conclusion: Both ATBT and TBT enhanced balance and ankle function in FAI patients. ATBT was more effective in improving balance and ankle function than TBT.

Microorganisms perform a crucial function in the biogeochemical processes that maintain soil quality. Nonetheless, the influence of biochar on soil microbial communities and their ecological functions remains poorly understood in black soils. To investigate this, a 2-year field experiment was conducted with four biochar application treatments: 0 t ha− 1 (CK), 6 t ha− 1 (BC6), 12 t ha− 1 (BC12), and 24 t ha− 1 (BC24). Microbial diversity and community composition under each treatment were assessed using high-throughput sequencing techniques. PICRUSt2 and FUNGuild were employed to predict microbial functional profiles. Compared to the control (CK), biochar addition led to notable shifts in both bacterial and fungal community structures. It also significantly enhanced bacterial α-diversity, as reflected by increased Shannon index, OTU counts, and Chao1 richness. However, a gradual decline in bacterial diversity was observed with rising biochar application rates. Taxonomic analysis revealed that biochar treatment significantly elevated the relative abundances of specific bacterial groups—such as Acidobacteria, Chloroflexi, Candidatus_Solibacter, and Bryobacter—as well as fungal groups such as Ascomycota, Zygomycota, Mortierella, Penicillium, and Fusarium. These effects were most evident under the moderate application rate (BC6). These microbial community changes may contribute to maintaining agroecological functions and soil health in biochar-amended soils. Regarding ecological functions, biochar application enhanced soil bacterial metabolic potential and saprotrophic fungal abundance, with more significant effects in the BC6 treatment, while reducing plant pathogenic fungi. This suggests beneficial effects on soil health maintenance and elemental cycling. Therefore, from the perspective of soil microbial community characteristics, biochar application positively influences black soil quality improvement. Considering environmental and economic benefits, a lower biochar application rate (6 t ha⁻1) may represent an optimal strategy for carbon sequestration, soil quality enhancement, and agroecological function maintenance in the studied system.

Background: Early recovery of cognitive function and lower-limb strength is critical for regaining mobility and independence after stroke. However, patients with cognitive impairment often have limited participation in conventional rehabilitation (CR). Objects: This study compared the effects of robotic tilt-table training (RT) group and CR group on cognitive function, lower-limb strength, balance, gait, and activities of daily living in patients with subacute stroke. Methods: In this retrospective study, 122 patients with subacute stroke were divided into two groups: the RT group and the CR group. The interventions were administered 5 times per week for a period of 4 weeks. Cognitive function was assessed using the Korean version of the Mini-Mental State Examination, muscle strength using Manual Muscle Test, spasticity using the Modified Ashworth Scale, balance using the Berg Balance Scale, gait using the Functional Ambulation Category, and activities of daily living using the Korean version of the Modified Barthel Index, both before and after the intervention. Data were analyzed using Wilcoxon signed-rank tests and Mann–Whitney U-tests. Between-group comparisons were performed on change scores (Δ = post − pre), and baseline differences were adjusted using ANCOVA or rank ANCOVA as appropriate (two-sided α = 0.05). Results: After 4 weeks of intervention, both groups showed within-group improvements in balance, gait, and activities of daily living (p < 0.05); however, the RT group demonstrated greater improvements in cognitive function and lower-limb muscle strength compared to the CR group. The two groups differed significantly in cognitive function and lower extremity muscle strength (p < 0.05) but not in spasticity, balance, gait, or activities of daily living (p > 0.05). Conclusion: RT may be effective in improving cognitive function and lower-limb strength in patients with subacute stroke, potentially serving as an adjunct rehabilitation strategy to promote early mobility and functional recovery. However, its effects on balance, gait, and spasticity were not significant, indicating the need for complementary task-specific training and further controlled studies.

Background: Endothelial cells (EC) that make up the inner wall of blood vessels play an important role in angiogenesis and vascular recovery. Cardiovascular disease caused by dysfunction of ECs has been reported as a major cause of death worldwide. Despite significant research so far, the underlying mechanism of dysfunction of ECs in cardiovascular disease progression is not yet fully understood. Although therapeutic transplantation of autologous ECs is limited due to lack of cell availability, adiposederived stem cells (ADSCs), known for their ease of procurement and high potential for differentiation, will provide promising solutions to generate autologous ECs. Methods: This study investigated the optimal differentiation of ADSCs into ECs under EBM-2 culture conditions supplemented with VEGF and BMP-4 in hypoxia (2% O2). Results: During 14 days of in vitro differentiation, cells cultured in EBM-2 supplemented with VEGF showed the characteristics of early vascular ECs and some cells adopted polygonal forms. Conversely, cells cultured in EBM-2 and hypoxia supplemented with both VEGF and BMP-4 differentiated into the typical cobblestone morphology that appears in vascular ECs. As a result of immunostaining against the vascular ECs marker CD-31, CD-31 expression was increased under EBM-2 culture conditions with VEGF and VEGF + BMP-4 in hypoxia, but expression was insufficient in normal oxygenation (21% O2). In the flow cytometry analysis, high expression of CD-31 expression was observed under conditions including both VEGF and BMP-4 of hypoxia. Interestingly, in gene expression, the pluripotency marker OCT-3/4 was significantly reduced under hypoxic conditions, but SOX2 and NANOG expression were higher than under normal oxygen conditions. However, CD-31 expression was significantly higher under differentiation conditions in which VEGF and BMP-4 were added under hypoxia conditions. In a functional analysis, CD-31-positive ADSC-derived ECs differentiated under hypoxia had excellent tube formation and Dil-Ac-LDL uptake, which are important for vascular repair and function. Conclusions: These findings confirmed the therapeutic usefulness of ECs derived from ADSC for the treatment of cardiovascular disease due to the synergy effect of hypoxia and BMP-4.

본 연구에서는 해양 유래 녹조류인 잎파래(Ulva linza) 열수 추출물(ULW)의 기능성 화장품 소재로서의 활용 가능성을 평가하고자 항산화 활성, 항산화 관련 성분 함량, 미백 및 주름 개선 관련 효 소 활성, 항균 특성, 피부세포 독성 및 항염 효능을 종합적으로 분석하였다. ULW의 항산화 활성은 DPPH 및 ABTS+ 라디칼 소거 실험을 통해 평가한 결과, 농도 증가에 따라 소거 활성이 증가하는 경향 을 보였으며, DPPH 라디칼 소거 활성은 전반적으로 낮았으나 800 μg/mL에서 약 24% 이상의 소거 활성을 나타냈다. 반면, ABTS+ 라디칼 소거 실험에서는 100 μg/mL 이상에서 소거 활성이 증가하여, 최고 농도인 800 μg/mL에서 약 91% 이상의 높은 소거 활성을 나타냈다. ULW의 총 플라보노이드 함 량은 16.56 mg QE/g, 총 폴리페놀 함량은 74.86 mg TAE/g으로 확인되어, 전반적으로 낮은 수준의 플 라보노이드 및 폴리페놀 함량을 나타냈다. 미백 및 주름 개선 관련 효능 평가를 위해 tyrosinase 및 elastase 저해 활성을 분석한 결과, ULW는 전 농도 범위에서 유의적인 효소 저해 효과를 나타내지 않았 다. 또한, 항균 활성 평가에서 ULW는 Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa 및 Cutibacterium acnes에 대해 항균 효과를 나타내지 않았다. 피부세포 독성 평가 결과, ULW는 대식세포(RAW 264.7), 각질형성세포(Kera-308), 섬유아세포(NIH-3T3) 모두에서 800 μg/mL 의 최고 농도까지 세포 생존율이 높게 유지되어 독성을 유발하지 않는 것으로 확인되었다. 한편, LPS로 유도된 RAW 264.7 대식세포 모델에서 ULW는 NO 생성과 iNOS 단백질 발현을 효과적으로 억제하여 항염 효과를 나타냈다. 이러한 결과를 종합할 때, ULW는 미백, 주름 개선 및 항균 효능은 제한적이었 으나, ABTS+ 라디칼 소거를 중심으로 한 항산화 활성과 우수한 항염 효능, 그리고 피부 관련 세포에 대 한 높은 안전성을 바탕으로 기능성 화장품 소재로서의 활용 가능성을 지니는 것으로 판단된다.

흙생강은 태국의 생강과(Zingiberaceae)에 속하는 식물로 의약품, 식품등의 소재로 활용되고 있 다. 이에 본 연구에서는 화장품 소재로 활용하기 위해 흙생강의 열수 추출물을 제조하고 항산화, 항염, 및 보습 효능을 확인하였다. 흙생강 열수 추출물의 총 폴리페놀 함량을 확인한 결과 약 163.69 ± 0.90 mg TAE/100 g의 함량을 보유하였으며 라디칼 소거능을 확인한 결과 ABTS 라디칼 소거활성이 우수함을 확인 하였다. 세포독성이 없는 농도에서 NO 생성 저해 활성을 확인한 결과 농도의존적으로 저해 효능이 나타났 다. 또한, 피부 보습 활성을 확인하고자 HA 생성량을 확인한 결과 10 μg/mL의 농도에서 기존 각질형성 세포보다 약 29.47%의 증가를 관찰하였다. 결론적으로 흙생강 열수 추출물은 화장품 소재로 항염 및 보습 효능을 나타내며 기능성 화장품 소재로 활용 가능성을 확인하였다.

본 연구는 45도 방향전환 동작 시 주동다리와 비주동다리 간 지면반력 특성을 다차원적으로 비교하고, 비대칭 지수(Asymmetry Index, AI)를 정량화하여 개인별 변이성과 그 기능적 의미를 규명하 는데 목적이 있었다. 오른발이 주동다리인 건강한 대학생 38명을 대상으로 45도 방향전환 시 주동다리 와 비주동다리의 지면반력을 측정하였다. 집단 평균 수준에서는 대부분의 지면반력 변수(peak vertical, posterior, medial GRF, horizontal resultant, frontal/sagittal plane angles, VLR)에서 양측 간 유의한 차이가 나타나지 않았다(p>.05). 그러나 개인별 AI 분석 결과, 평균 22.6±16.6%(범위: 1.4-64.9%)로 높은 변이성을 나타내었으며, 71.1%가 잠재적 부상 위험 기준(10%)을 초과하였다. High AI 그룹 (n=27)은 Low AI 그룹(n=11)에 비해 peak posterior GRF(0.87 vs. 0.71, p=.009), horizontal resultant GRF(1.23 vs. 1.06, p=.004), sagittal plane angle(15.84 vs. 13.86°, p=.025)에서 유의하게 높은 수치 를 나타내었다. 이는 비대칭이 클수록 제동력과 수평면 힘 생성이 증가하며, 부상 위험이 증가될 수 있 음을 시사한다. 본 연구 결과는 집단 평균만으로는 개인의 비대칭을 평가하기 어려우며, 개인 맞춤형 평 가와 중재가 필요할 것으로 판단된다.

This study aimed to identify the optimal storage and germination conditions for producing sprouts from immature bulbils of the Korean garlic cultivar ‘Hongsan’. It also evaluated the effects of LED light quality on sprout growth and compared the functional compound contents across different plant parts. Germination trials indicated that storing bulbils at 4°C for at least 64 days, followed by germination at 10-20°C, yielded the best results. Under mixed LED light treatments (Red:Blue:White), a red-dominant ratio of 4:1:0 significantly enhanced both shoot and root elongation, while germination in darkness resulted in the highest fresh and dry weights. Among the plant parts, sprouted bulbils had the highest alliin content (3,711 mg/100 g) and contained greater levels of fructose and glucose compared to cloves. Conversely, cloves had the highest fructan content, and leaves exhibited the highest total polyphenol content. These findings underscore the importance of combining proper storage and light quality for efficient sprout production from bulbils and highlight the potential of sprouted bulbils as functional food materials.

This study examined the structural, physicochemical, and functional characteristics of five black soybean (Glycine max (L.) Merr.) cultivars—Cheongja5, Danheuk, Socheongja, Seum, and Soriheuk—bred and cultivated in Korea. We conducted comprehensive analyses on morphology, microstructure, thermal and hydration properties, pasting behavior, and antioxidant activity to identify cultivar-specific differences in processing suitability and functional properties. The results indicated significant varietal variations in seed coat ratio, cotyledon density, and color, which affected thermal stability, hydration, and viscosity development during heating. Cultivars with compact cotyledon matrices, such as Cheongja5 and Danheuk, displayed high enthalpy (ΔH), low solubility, and limited viscosity development, suggesting high structural stability and low thermal reactivity-traits favorable for thermally stable or beverage-type applications. In contrast, cultivars with looser structures and greater surface exposure, like Seum and Socheongja, exhibited higher swelling power, dispersion stability, and RVA viscosities, indicating their suitability for viscous or semi-solid systems. Notably, Soriheuk showed the highest antioxidant activity and levels of phenolic and flavonoid compounds, correlating with its high seed coat ratio and dark pigmentation, positioning it as a promising functional ingredient. These findings underscore that the physicochemical and structural diversity among black soybean cultivars significantly influences their processing performance and functional potential, providing a scientific foundation for selecting and developing functional cultivars.

This study explored how enzyme type (cellulase and pectinase), concentration, and mixing ratio influence the functional compounds and antioxidant activities of purple sweet potato (Ipomoea batatas L.). The enzyme treatment significantly impacted all measured parameters. At a cellulase concentration of 30 units, the total anthocyanin content reached 399.4 mg/100g dry weight (DW), representing a 163% increase compared to the control (151.6 mg/100g DW). Total polyphenol (1,799.7 mg GAE/100g DW) and flavonoid (475.3 mg CE/100g DW) contents also peaked under these conditions, while higher enzyme concentrations or increased pectinase ratios reduced extraction efficiency. The highest ABTS radical scavenging activity was noted at 30 units of cellulase (954.0 mg TE/100g DW) and at 80 units in a combined treatment of cellulase (2) to pectinase (1) (927.2 mg TE/100g DW), suggesting that moderate enzyme synergy enhances antioxidant release. Conversely, DPPH activity decreased with higher enzyme concentrations, with all combined treatments yielding lower results than the control. Overall, the optimal condition for enhancing both functional compound extraction and antioxidant activity in purple sweet potato was identified as a single treatment with cellulase at 30 units.

This study optimized the extraction of β-carotene and antioxidant compounds from orange-fleshed sweet potato (Ipomoea batatas L.) using response surface methodology (RSM) with ethyl lactate as a green solvent. A central composite design (CCD) was utilized to evaluate how the solvent-to-sample ratio, temperature, and extraction time affected efficiency. The regression model was statistically significant (Adj. R2=0.67), revealing that the solvent-to-sample ratio was the most influential factor, while temperature and time had relatively minor effects. The optimal conditions identified were a ratio of 12 mL/g, a temperature of 35°C, and an extraction time of 30 minutes, which resulted in a yield of 27 mg/100g of β-carotene, along with high levels of polyphenols, flavonoids, and strong antioxidant activities as measured by DPPH (2,2-diphenyl-1-picrylhydrazyl) and ABTS (2,2'-azino-bis(3-ethylbenzothiazoline- 6-sulfonic acid)) assays. Validation experiments demonstrated a close alignment between predicted and experimental values, confirming the model's robustness. These findings indicate that ethyl lactate effectively extracts not only carotenoids but also a wide range of antioxidants, underscoring its potential as a sustainable solvent for developing functional food ingredients.

곤충의 외골격/표피(exoskeleton/cuticle)는 구조 다당류인 키틴(chitin)과 큐티클 단백질(cuticle proteins)로 이루어진 세포외기질 (extracellular matrix)로서 외부 환경스트레스, 물리적 손상과 병원성 미생물 등으로부터 자신을 보호하는 피부와 골격의 역할을 한다. 그러나 곤 충은 원래 가지고 있던 표피를 분해하고, 새로운 표피로 교체하는 ‘탈피(molting 또는 ecdysis)’를 주기적으로 거쳐야 정상적인 성장과 발달을 할 수 있다. 따라서, 곤충은 탈피 과정마다 원래 가지고 있던 표피 일부를 분해하는 동시에 안쪽에는 새로운 표피를 생성한다. 이 과정에서 탈피액에 있 는 키틴을 가수분해하는 효소인 chitinases (CHTs)와 N-acetylglucosaminidases (NAGs)가 오래된 표피(old cuticle)의 키틴 섬유를 분해하는 데 중요한 역할을 한다. 최근에는 이들 chitinolytic enzyme들과 함께 lytic polysaccharide monooxygenases (LPMOs)가 키틴의 glycosidic bonds를 산화적으로 절단하여 오래된 표피를 효과적으로 분해한다는 것이 새롭게 밝혀져 주목을 받고 있다. 본 종설에서는 곤충의 탈피 과정에서 CHTs와 LPMOs의 생리학적 기능을 기술하고, 오래된 표피의 결정성 키틴을 분해하는 과정에 대한 새로운 분자 기작을 소개하고자 한다.

중국어 구말조사에 대한 연구는 중국어학계의 지속적인 주목을 받아 왔으며, 선행 연구자들은 다양한 언어학 이론을 바탕으로 이에 대한 유의미한 탐구를 수행해 왔다. 그 결과 중국어 구말조 사에는 여러 기능적 특징이 부여되었으나, 서로 다른 층위의 기능적 특징들이 혼재되면서 오히려 논의가 복잡해지는 문제도 나타났다. 본고는 ‘어기’범주의 초기 개념과 분류를 토대로, [+주요 문장 유형 분포], [+양태 범주], [+발화행위적 기능], [+발화행위력 조정], [+주관성], 그리고 [+상호 주관성]을 매개 변수로 삼아 학계의 일반적인 구말 어기사 연구 성과를 정리·귀납하고, 나아가 기능문법 이론(TFG)과의 결합을 통해 중국어 구말조사의 중복 사용 원인을 구명하고자 한다.

This study aimed to elucidate the functional correlation between G-protein activation and Ca²⁺ signaling during hypotonic shock-induced cell swelling in human osteoblast-like cells. Calcium influx was investigated using fura-2 fluorescence imaging, specific channel blockers, and G-protein modulators such as cholera toxin (CTX) and pertussis toxin (PTX). The external solution contained hypotonic Na⁺, and 300 M Cd²⁺ was applied to assess the involvement of extracellular Ca²⁺ channels. Calcium influx was significantly inhibited by Cd²⁺, indicating an extracellular source of Ca²⁺ through specific channels. CTX prolonged the hypotonic Na⁺-induced elevation of intracellular Ca²⁺, while PTX completely abolished it. These results suggest the involvement of G-protein-mediated pathways in Ca²⁺ regulation. Furthermore, the CTX-induced potentiation implies regulation via the cAMP/protein kinase A signaling axis, indicating that stretch sensitivity may be modulated by hormone-activated adenylate cyclase. This study is the first to demonstrate a functional link between hypotonic stress-induced Ca²⁺ influx and G-protein activation in human osteoblast-like cells, potentially involving a novel Ca²⁺ channel regulated by the cAMP/PKA pathway.

본 연구에서는 고효율 non-fullerene acceptor인 Y6의 전자구조 및 광학 물성을 정확하게 예측하기 위해 Koopmans’ theorem 기반의 optimally tuned (OT) LC-DFT와 polarizable continuum model (PCM)을 결합한 단분자 계 산 접근법을 제안한다. μ 최적화 결과, 같은 분자식 안에서 구조적 차이는 최적의 μ 값에 큰 영향을 미치지 않는 반면 기체상(gas-phase)과 응집상 환경(PCM) 간에는 뚜렷한 μ 값의 차이가 나타나며 용매 환경 효과에서 계산된 μ 값이 기 체상보다 더 작게 계산이 된다. PCM에서 최적화된 OT-LC-DFT는 고체 시료의 실험적인 이온화에너지, 전자진화도, fundamental gap과 가장 잘 일치하는 결과를 보였으며, TD-OT-LC-ωPBE로 계산된 흡수 스펙트럼은 용액 및 박막 상태 에서 관측된 근적외선 영역의 최대 흡수 피크와 적색 이동을 잘 재현하였다. 또한 HOMO/LUMO 전자 분포 분석을 통 해 μ 값에 무관하게 분자내 전하 이동(ICT) 특성이 유지됨을 확인하였다. 이러한 결과는 단분자–PCM 기반 OT-LC-DFT가 응집상 환경에서의 전자구조와 광학 물성을 신뢰성 있게 예측할 수 있는 실용적 계산 방법임을 보여준다.

본 연구는 초고령노인의 신체적 기능상태가 삶의 만족도에 미치는 영향을 분석하고, 우울과 지역사회환경만족도의 매개효과를 검증하여 실 천적 함의를 도출하고자 하였다. 보건복지부와 한국보건사회연구원의 2023년 노인실태조사 자료 중 80세 이상 초고령노인 2,399명의 응답 을 활용하였다. 본 연구 결과, 첫째 우울은 삶의 만족도에 부적으로 유의한 영향을 미쳤으며, 학력과 배우자 유무 또한 삶의 만족도에 영향을 주었다. 둘 째, 우울은 신체적 기능과 삶의 만족도의 관계를 매개하여, 신체 기능 저하가 우울을 높이고 삶의 만족도를 낮추는 경향이 나타났다. 셋째, 지 역사회환경만족도의 단독 매개효과는 통계적으로 유의하지 않았으나, 신 체적 기능이 우울과 지역사회환경만족도를 통해 삶의 만족도에 간접적으 로 영향을 미치는 이중매개효과가 확인되었다. 이러한 결과는 초고령노 인의 삶의 만족도가 신체적, 심리적, 환경적 요인이 복합적으로 작용한 결과임을 시사한다.