Some flavonoids such as baicalin, baicalein, wogonin and skullcapflavone are present in Scutellaria baicalensis Georgi as main components. We fermented Scutellaria baicalensis Georgi (it called as SB) extract with mycelium of Leatiporus sulphureus var. miniatus, Grifola frondosa and lsaria japonica respectively for 6 days. As a result, we found that baicalin was converted into baicalein through bioconversion process only when fermented by mycelium of Leatiporus sulphureus var. miniatus, but not by other. We confirmed that baicalein was increased from 3241.4 ppm to 18622.6 ppm while baicalin was decreased from 35970.5 ppm to 11833.8 ppm after fermentation by HPLC analysis. It ment that bioconversion by fermentation increased baicalein contents 5.8 times (It called as G/Baiclein).