Osteoarthritis is a degenerative joint disease and is led to physical disability. Yet the development of effective disease-modifying treatments has lagged. In this study, I examined the effect of physical therapeutic intervention through microcurrent stimulation and attempt to find which degree of intensity, either 25 or 500 with a regular 5 pps pulse, is more effective in the osteoarthritis. Osteoarthritis was induced with a mixture of 2% carrageenan and 2% kaolin in 26 male Sprague-Dawley rats. The mixture (0.1 ) was injected into the intra-articular capsule of knee joint once a week for three weeks. Five animals did not show degenerative changes by radiological findings and excluded in the following experiment. Osteoarthritic animals were randomly divided into 3 groups (, , =7/each): untreated, treated with 25 , treated with 500 . All experimental groups received microcurrent stimulation for four weeks (15 min/day, 5 days/week). The ethological inspection of foot print analysis on the walking corridor was accomplished every week. Histological preparations and immunohistochemical staining with insulin-like growth factor-1 were also done in the articular cartilages. All of these parameters were compared with those of osteoarthritic control group (n=7). The ethological inspection of foot print analysis revealed that changes of walking track (paw width) and stride length was significantly increased in both experimental groups. The better results were observed in experimental group treated with 25 intensity without significance than group treated with 500 . Histological preparations disclosed that routine hyaline cartilage of articular surface were altered to fibrous cartilage in untreated group and experimental group treated with 500 intensity. But a little changes were seen in experimental group treated with 25 intensity. Immunolocalization of insulin-like growth factor-1 was simultaneously decreased according to the duration of osteoarthritis, and did not show significant difference among the groups. In this study discovered that the microcurrent stimulation, especially 25 intensity, had a positive effect by the ethological inspection, histological and immunohistochemical stainings. These results suggest that microcurrent stimulation with low-intensity might be effective in the promotion of healing process for the osteoarthritis.

The purpose of this study was to assess visual biofeedback's influence on trunk muscles' (EMG) activity and endurance holding time for correct position during whole-body tilt exercise. For the study, we recruited 14 volunteers who showed no symptom of lumbar disease during medical tests. We measured the EMG activity of their rectus abdominis, external abdominal oblique, internal abdominal oblique and erector spinae muscles, and their endurance holding time for correct position during anterior and posterior whole-body tilt under two conditions: whole-body tilt with and without visual biofeedback. Resistance with gravitational force on the trunk during whole-body tilt was applied by using a device that had a monitor on which the subjects could check their alignment and that sounded an alarm if a subject's alignment collapsed. The study showed an increase in the EMG activity of external abdominal oblique, internal abdominal oblique/rectus abdominis ratio and endurance holding time for correct position during both anterior and posterior whole-body tilt with visual biofeedback compared with without visual biofeedback (p<.05). We suggest that the whole-body tilt exercise with visual biofeedback could be a beneficial strategy for selectively strengthening the internal abdominal oblique muscle and minimizing the rectus abdominis muscle's activity while maintaining correct alignment during whole-body tilt exercise.

This paper describes the fabrication of AlN thin films containing iron and iron nitride particles, and the magnetic and electrical properties of such films. Fe-N-Al alloy films were deposited in Ar and N2 mixtures at ambient temperature using Fe/Al composite targets in a two-facing-target DC sputtering system. X-ray diffraction results showed that the Fe-N-Al films were amorphous, and after annealing for 5 h both AlN and bcc-Fe/bct-FeNx phases appeared. Structure changes in the FeNx phases were explained in terms of occupied nitrogen atoms. Electron diffraction and transmission electron microscopy observations revealed that iron and iron nitride particles were randomly dispersed in annealed AlN films. The grain size of magnetic particles ranged from 5 to 20 nm in diameter depending on annealing conditions. The saturation magnetization as a function of the annealing time for the Fe55N20Al25 films when annealed at 573, 773 and 873 K. At these temperatures, the amount of iron/iron nitride particles increased with increasing annealing time. An increase in the saturation magnetization is explained qualitatively in terms of the amount of such magnetic particles in the film. The resistivity increased monotonously with decreasing Fe content, being consistent with randomly dispersed iron/iron nitride particles in the AlN film. The coercive force was evaluated to be larger than 6.4×103Am-1 (80 Oe). This large value is ascribed to a residual stress restrained in the ferromagnetic particles, which is considered to be related to the present preparation process.

발달장애아동은 사회적 의사소통의 기술을 개발하기 위하여 이른 시기의 진단과 의학적 치료가 매우 중요하다. 하지만 발달장애아동들은 공공 복지기관과 전문 의료시스템의 부족으로 인하여 의학적 치료에 큰 어려움을 가지고 있다. 특히 적은 수의 아동만을 대상으로 해야 되는 일대일 면접치료방법의 특이성으로 인하여 발달장애 아동은 장소, 시간, 비용의 문제에 직면하고 있다. 이러한 문제점을 해결하기 위하여 다양한 상호작용의 기술과 보조기술, 서비스가 개발되고 있으며, 본 논문은 이러한 상호작용 디자인의 가능성을 탐색하고 더 나아가 치료시스템의 구체적 디자인개발을 목표로 한다. 본 연구는 학제간 협업, 빠른 프로보타입 개발, 전문가와 사용자 평가중심의 프로세스, 가상현실 기술, 시나리오 중심의 디자인을 주요 개발 방법론으로 적용하여, 상호작용치료시스템(ITS)의 구체적 사례를 개발하였다. 또한 상호작용치료시스템(ITS)을 치료기관과 협력하여 실제 임상실험에 적용함으로서 이러한 상호작용 다자인의 효용성과 타당성, 활용방안 등을 검증하였다.

서식지 파편화로 발생하는 야생동물과 차량과의 충돌사고(이하 '로드킬')를 방지하기 위해 2000년대 후반부터 야생동물이동통로가 활발하게 설치되었으나 로드킬 발생은 여전히 감소하지 않고 있어 야생동물이동통로의 실효성 분석이 필요하며, 설치 이후 단편화된 유지관리로 인해 야생동물이동통로에 대한 평가 및 기능개선을 위한 관리기법이 부족한 실정이다. 이에 본 연구에서는 야생동물이동통로의 유지관리를 위한 기본방향 및 관리기법을 제시하기 위해 현재 설치 운영되고 있는 367개 이동통로에 적용할 수 있는 평가항목과 항목별 중요도를 AHP 기법에 의해 파악하였다. 분석결과, 평가항목은 3단계로 구분할 수 있었으며 총 10개 평가항목이 도출되었다. 야생동물이동통로의 유지관리를 위한 우선순위 도출을 목표(Level 1)로 시설인자, 환경인자, 동물인자, 관리인자로 구성된 Level 2의 중요도 분석에서는 환경인자가 가장 중요한 것으로 나타났다. Level 3에서는 구조 적합성(시설인자), 주변지형과의 조화(환경인자), 야생동물 이용빈도(동물인자), 모니터링 기기 운영여부(관리인자)가 중요 평가항목으로 조사되었다. 즉 야생동물이동통로의 유지관리를 위해서는 주변지형과의 조화와 야생동물 이용빈도를 우선적으로 고려해야 할 것이다. 이같은 연구 결과는 우리나라에 설치되어 있는 야생동물이동통로의 유지관리 방향 및 각 이동통로의 정비전략을 모색하기 위한 평가자료로 활용될 수 있다.

본 논문에서는 Funology(퍼놀로지)와 몸의 체험 통해 형성된 언어개념 및 사고를 바탕으로 새로운 어플리케이션 분류 체계를 연구하고, 이를 Funology Body로 명명하였다. Funology Body는 크게 몸, 세계(환경), 디바이스 툴의 구성을 가진 분류 및 검색 체계이다. 몸은 신체의 부위에 따라 Brain, Eyes, Ears, Nose, Mouth, Hand, Torso, Feet, Heat로 구분할 수 있는데, 몸 부분의 개념과 관련된 앱을 연결시켜 분류체계를 구성함으로써 쉽고 직관적이며, 체험적인 검색을 가능하게 하였다. 봄의 구성 중 Brain은 사고와 관련된 어플리케이션을 포함할 수 있도록 Book, Account, Business, Memory, Education, Search, Aphorism로 하위분류되어 있으며, Eyes는 시각과 관련된 Video, Photography, Broadcast로, Ears는 청각과 관련된 Music, Instrument, Audio, Radio로, Nose는 후각과 관련된 Perfume, Smell로, Mouth는 먹을 것 및 의사소통과 관련된 Food, SNS, Chatting, Email, Blog로 Hand는 조작하고 만들고 장난치는 것과 관련된 Games, Kits, Editing으로 Torso는 내장을 보호하고 몸의 중심을 이루는 개념과 관련된 Health, Medical, Dance, Sport, Fashion, Testyuorself로 Feet는 이동하여 영토를 넓히는 개념과 관련된 Travel, Transportation, Map, Outdoor로, Heat는 감정과 관련된 Fear, Anger, Joy, Sadness, Acceptance, Disgust, Expectation, Surprise로 이루어져 있다. 그밖에 세계(환경)는 News, Time, Weather, Map, Fortune, Shop으로 디바이스 툴은 Interface, Utilities로 구성되어 있다. 직관적이고, 감각적인 재미를 줄 수 있다는 것뿐만 아니라 변화하는 어플리케이션 사용자의 태도와 취향을 유연성 있게 반영할 수 있다는 점에서 기존 분류체계와는 다른 Funology Body의 특정을 찾을 수 있다.

본 연구는 서울대공원 동물원에서 실시되고 있는 5개 해설프로그램의 만족도와 인식변화를 참가자 설문을 통해 분석하였다. 연구결과 프로그램의 전체 만족도는 높았으나, 이 중 참가자 태도에서 상대적으로 낮은 만족도를 보였으며 학부모가 안전성 측면에서 우려하는 정도가 높은 것으로 분석되었다. 각 프로그램 간 만족도는 프로그램별로 차이가 있는 것으로 분석되었으나 내용만족도에 있어서는 차이가 없었다. 마지막으로 각각의 동물해설 프로그램은 다소의 차이는 있으나 동물원에 대한 긍정적 인식변화에 영향을 주는 것으로 나타났다. 동물원의 환경해설 프로그램은 동물원에 대한 정보를 보다 효과적으로 전달할 수 있는 매개로 작용하는 것을 확인하였으며, 동물원의 기능이 단순한 전시기능이 아닌 교육과 연구 등 다양하게 이루어지고 있다는 것을 통해 관심 또한 증대시킬 수 있는 효과적인 수단으로 작용하는 것으로 판단되었다. 이에 동물원 환경해설 프로그램을 보다 활성화 시킬 필요성이 있었다.

This research was carried out as a survey on the contents of Lead (Pb) and Cadmium (Cd) in 5 type agricultural products unestablished safety guideline in Korea. The average levels of Pb: onion 0.010 mg/kg, cucumber 0.018 mg/kg, garlic 0.012 mg/kg, green pepper 0.027 mg/kg, sesame 0.029 mg/kg. The average levels of Cd: onion 0.006 mg/kg, cucumber 0.002 mg/kg, garlic 0.008 mg/kg, green pepper 0.011 mg/kg, sesame 0.024 mg/kg. The present result of this study showed that Pb and Cd contents in the whole samples were less than the maximum residual levels of the codex standard. The levels of exposure assessment for Pb and Cd by intake from vegetables and sesame were merely at 1.3 × 10−⁴(mean) ~5.1 × 10−⁴(95th percentiles) μg/kg bw/day for Pb, 7.5 × 10−5(mean)~3.6 × 10−⁴(95th percentiles) μg/kg bw/day for Cd. The data from this research will be valuable source for database construction for science-based safety control and management for the trace metal contamination in food including agricultural products.

Nontuberculous mycobacteria (NTM) often confounds the interpretation of skin test in tuberculosis diagnosis, resulting in false-positive reaction. And, NTM are emerging pathogens that cause opportunistic infections in both humans and animals. The prevalence of NTM on human disease has been well investigated, whereas that of NTM on animal disease is not well established in Korea. The aim of this study was to determine the prevalence of NTM on cattle, which did not have symptoms of tuberculosis disease. A total of 426 isolates were collected in Korean native cattle and dairy cattle from 2007 to 2010. The most frequently isolated organisms were Mycobacterium peregrimum (n=5, 28%), Mycobacterium fortuitum (n=3, 17%), Mycobacterium intracellulare (n=2, 11%), Mycobacterium phlei (n=1, 5.6%), Mycobacterium terrae (n=1, 5.6%), Mycobacterium llatzerense (n=1, 5.6%), and Norcadia spp. (n=1, 5.6%). It seems to be necessary to further study the prevalence of NTM on environment (water, soil, feces) as well as animals.

A water purifiers for home-use has been popularly used as increasing distrust of the drinking tap water in views of safety. Besides, chlorination of drinking water can produce trihalomethanes known as a carcinogens. In general, a water purifier is known to remove risk factors such as infectious microorganisms, harmful chemicals and heavy metals. We compared the change of water components before and after purification by a water purifier and evaluated the results whether this purification system is reliable or not for safety of drinking water. The samples of water from 11 sites at the campus of Jeju National University were examined by physicochemical analyses, including concentration of sodium, potassium, chloride, residual chlorine, boron, nitrate nitrogen, sulfur, hexavalent chromium, copper, iron, aluminium, silicon, selenium, vanadium, manganese, molybdenum, nickel, arsenic, antimony, zinc, cadmium, lead, strontium. Microbiological analysis was performed by counting mesophilic bacterial colonies. Almost of all the physicochemical components after purification were shown to decrease tendency of their concentrations but not significantly differenty except that of residual chlorine. Mesophilic bacterial counts after purification were shown to increase when compared to those of tap water. All the tap water was met the acceptance of requirement of drinking water, but samples of the water after purification were failed (4 from 11). After draining generous amount of water from a purifier, bacterial counts were observed to show a decreased tendency. Bacterial colonies were not detected when the concentration of residual chlorine was higher than 0.2 ppm. Although seasonal factors and maintenance condition were not concerned in this study, higher bacterial counts in purified water could cause some problems in using water purifier for home-use. Considering the results obtained, regular maintenance and care including filter change and sterilizing the reservoir are absolutely required. A further study is required to examine where the bacteria are coming from.

This study was planned to monitor the change in the content of sulfur dioxide during the drying process of fresh vegetables. The analysis of sulfur dioxide was conducted by the Optimized Monier-Williams Method based on the Korea Food Code. The samples were kinds of vegetables which consisted of naturally-originated sulfur compounds (green onion, onion, cabbage, garlic, radish leaves, radish). Fresh vegetables (n = 182) and dried vegetables (n = 41) purchased from different local areas were investigated for the content of sulfur dioxide. The fresh vegetables were dried at 50~60℃ using hot-air dryer. The moisture contents of dried samples were adjusted to keep 10percents. The contents of sulfur dioxide in self-dried vegetables were 104.6 mg/kg in green onion, 75.4 mg/kg in onion, 129.1 mg/kg in cabbage, 197.6 mg/kg in garlic, 23.0 mg/kg in radish leaves and 52.5 mg/kg in radish, respectively. The increase of sulfur dioxide content according to the moisture content reduction was different from the expected. It means that the contents of sulfur dioxide can be altered by other factors except moisture contents. This results can be utilized as materials for the safe management of sulfites of dried vegetables.

Porcine reproductive and respiratory syndrome (PRRS) virus causes not only breeding disorder such as abortion, stillbirth and premature birth to pregnant sows but economic damage like high estrous return and low delivery rate. The presented study was conducted to confirm seroprevalence of PRRS in Jeju herds. PRRS positive rate was examined with pig serum from hog farms located in Jeju. Serum samples were extracted from the 11 of sow farms and 10 of hog farms, The groups were divided into 20, 40, 60, 80, 100 and older than 120 days of age and pregnant sows in hog farms. Anti-PRRSV antibody titers in sera were analyzed by ELISA. All the breeding farms and hog farms (10/10) showed PRRS positive except one breeding farm (1/11). Serological patterns determined by ELISA did not show any difference regardless of whether pigs were vaccinated or not. Nevertheless, the farms unvaccinated pigs displayed low productivity in terms of piglet loss rate and prolonged period of shipment. Therefore, vaccination against PRRSV appears to be a crucial factor in sanitary management of hog farms. Taken together, since PRRSV was spread widely in Jeju already, stabilization of sows by PRRS vaccination after adapting PRRSV free sow by all-in-all-out method in farms is recommended for the control strategy for PRRS.

Toxicity of 3-MCPD that comes from food manufacture and processing is well-known. Recent studies reported that 3-MCPD fatty acid ester which is formed by metabolic material was 10~2000 times as much as 3-MCPD in food. This study made analysis method of 3-MCPD fatty acid esters by recent research and laboratory work, and determined the content of 3-MCPD and 3-MCPD fatty acid esters in sources and meat processing products. 3-MCPD fatty acid esters were analysed by GC/MS, which were hydrolyzed from fatty acid and then transferred 3-MCPD was extracted and reacted with derivative subject. As a result of analysis method validation, LOD was 5.4ppb,LOQ was 9.0ppb.

Salmonellosis is the commonest zoonosis worldwide that generally causes enterocolitis and foodborne poisoning which represents a considerable public health burden. Salmonella spp. are potential enteric pathogens and intracellularly replicates in host cells resulting in chronic infections. The medical treatments for salmonellosis have been difficult yet and had a serious problem including the increasing emergence of antibiotic resistance. The present report was designated to investigate the antibacterial effects of Saururus chinensis Baill ethanol extract (SCEE) on pure culture and infection with Salmonella enterica serovar Typhimurium (S. typhimurium) in murine derived macrophage RAW 264.7 cells. In determination of antibacterial activity of SCEE against S. typhimurium, bacterial viability was markedly decreased compared to the control. Also, SCEE significantly induced morphological change (p<0.05) of RAW 264.7 cells. In infection assay of S. typhimurium in RAW 264.7 cells pretreated with 100㎍/㎖ of SCEE, which is a non-cytotoxic concentration, bacterial uptake ability of macrophage was increased corresponding with morphological change, whereas bacterial survival rates within macrophage were markedly reduced compared with untreated control. Furthermore, nitric oxide (NO) production in SCEE-treated cells was slightly increased until 2 h but showed a tendency of decrease after 4 h until 24 h post infection compared with untreated control with S. typhimurium infection. Taken together, these findings demonstrated that SCEE has the antibacterial activity for S. typhimurium and the protective effects against S. typhimurium infection through activating murine macrophage independent on NO, suggesting that SCEE may be beneficial on the disease caused by intracellularly replicating pathogens as a safe alternatives of conventional chemotherapies.

멀티미디어 데이터를 응용하는 분야가 매우 많은 분야로 확대되어 왔으며, 현재 게임의 다양한 분야가 멀티미디어 데이터를 이용한다. 이러한 멀티미디어 콘텐츠의 양적인 급격한 팽창은 자연적으로 게임 콘텐츠 관리에서도 보다 체계적인 기술도입을 요구하게 된다. 멀티미디어 데이터를 컨트롤하기 위해서는 멀티미디어 데이터를 최적화 하여 수행하는 하드웨어 시스템이 필요하며, 소프트웨어 분야로 멀티미디어에 대한 다양한 연구가 필요하다. 소프트웨어 분야의 다양한 연구 분야로는 멀티미디어 압축, 영상 인식, 패턴 인식, 객체 영상 구축 등에 대한 연구가 이에 해당한다. 본 논문은 멀티미디어의 하드웨어와 다양한 소프트웨어의 시스템을 구축하고 연결하는 방법을 소개 한다. 게임에서의 동영상 재생컨트롤이 가능한 하드웨어 시스템과 국제 표준 규약인 MPEG-2와 MPEG-4 MPEG-7과 연계되는 영상 저장 방법 및 객체 지향 방식의 영상 데이터 저장 방식과 패턴 인식을 기반으로 하는 영상 인식 방법을 소개한다.

This study developed the pressure measurement monitoring system named VIP-2000 for monitoring a pressure of ullage space in cargo tank. VIP-2000 is designed in compliance with IMO(international maritime organization) SOLAS 74, Chap. II-2 Req. 59. IMO is providing the establishment of a pressure measurement equipment for secure the stability from vacuum or the overpressure that caused by in breakdown of the P/V valve. VIP-2000 operates the early warning of the visible and audibility in dangerous situation of cargo tank. In order to evaluate the performance of VIP-2000, the pressure measurement experiments have been conducted.