In this paper, we compared the efficiencies of national R&D investments between NT (Nanotechnology) areas in terms of papers, patents, and commercializations, and found ways to improve the efficiencies of national R&D investments for each NT area. This is in response to huge R&D investments government has made recently in NT areas.Here, we collected data on investments, papers, patents, and commercializations for the R&D projects in NT areas through National Science & Technology Information Service. Based on the data, we analyzed the investment and performances (papers, patents, and commercializations) for each NT area, calculated the efficiency for each NT area, and compared the efficiencies between NT areas. Next, using cluster analysis, we identified several NT areas with similar characteristics in terms of paper efficiency, patent efficiency and commercialization efficiency. Finally, we derived implications for the efficiency enhancement for each grouping.The cluster analysis showed that there could be two groups, one being low in terms of technological outcome (papers and patents) efficiencies and high in terms of commercialization efficiencies, while the other being high in terms of technological outcome (papers and patents) efficiencies and low in terms of commercialization efficiencies. Therefore, the strategy for one group calls for support for technology transfer or technology introduction from other R&D performers and grant of guidance for improving R&D performers’ commercialization ability to other R&D performers while the strategy for the other group calls for R&D support for transfer of technology to other R&D performers, activation of technology transfer and support for commercialization of R&D performers.

Dendrolimus superans (Lepidoptera: Lasiocampidae) has long been acknowledged to present in South Korea under the circumstance of a substantial change in species names of Dendrolimus. In the present study, we found that specimens of D. superans collected from South Korea were D. sibiricus, rather than D. superans. Comparison of Korean specimens to the D. superans from Japan and the D. sibiricus from Russia in terms of wing morphology, female and male genitalia, a partial COI gene sequence, and a partial internal spacer sequence 2 (ITS2) consistently supported the presence of D. sibiricus in South Korea. Phylogenetic analyses using concatenated sequences of COI and ITS2 from available individuals of D. sibiricus and D. superans both by Bayesian inference and maximum likelihood methods the Korea samples to be D. sibiricus.

The genus Diadegma is a well known parasitoid group and some are known to have symbiotic virus. A novel IV was discovered from the calyx of D. fenestrale female. This virus was named as D. fenestrale Ichnovirus (DfIV) and its genome contains 62 circular DNA segments with an aggregate size of approx. 240kb. We examined its gene expression patterns depending on the hosts (hymenopteran host, D. fenestrale and lepidopteran host, Plutella xylostella) and stages of P. xylostella based on RNAseq. Among 62 genome segments, only two segments such C15 and D14 were highly expressed in ovary of D. fenestrale. On the other hands, five segments were differently expressed depending on the developmental stages (3 rd and 4 th instar larvae). Additionally we confirmed integration of DfIV genome segments into the chromosome from the Plutella xylostella via genome sequencing of the lepidopteran host.

In order to distribute agricultural robots to the fields, based on the review of Japanese trends, three preliminary tasks and implications for the development of agricultural robots in Korea are derived as followings. The first result is that farmers are small-scale, agricultural robot is necessary to standardize through the public-private partnerships and reduce the supply price through the utilization of existing technologies and components. Secondly, the car-based robots are GPS-based system, and it is necessary to construct a nation-wide regional base stations that can trensmit the GPS correction signals free of charge in real time. Third, additional research is needed to cope with the unexpected situation in the fields, such as obstacle avoidance technology, robot safety evaluation technology, and safety standard development. In addition, although agricultural robots are being developed in Korea, a step-by-step approach is necessary for solving the above-mentioned pre-requisites for field distribution. In the first stage, it is necessary to supply an autonomous straight guidance system that assists the worker. The second stage is the spread of cooperation system between human and robot. The third stage is a complete robot system, in which the robot works on its own. Therefore, the supply of agricultural robots needs to be approached sequentially.

This study proposes that Malevich's 1913 performance “Victory Over the Sun” was not just Cubo Futurism, but that it produced Suprematism in the early 20th century. “Victory Over the Sun” did away with traditional set and costume design and a call to the Russian avant garde. Therefore, this study analyzes the characteristics of set and the costume design in “Victory Over the Sun”, and considers how it impacted twenty-first century fashion designers like Margiela. The results of the study are as follows: first, Margiela reinterpreted the characteristics of the costumes featured on “Victory Over the Sun” from a cubist perspective and represented geometric spatial structures and mechanical human images through changes in methods and materials. second, he designed costumes by applying to the set and costumes expressed black & white images on “Victory Over the Sun”. and third, Margiela reinterpreted the warrior image using geometric forms and colors in a creative way. Contemporary fashion designers, including Margiela, express their artistic creativity through various representational and materials choices. They want to convey their subjective personality and emotional sensibility to the public by mixing and deforming existing arts like painting, sculpture, and crafts to create new images. Thus, the creative intentions of the latest fashion designers have expanded art of costume design, exemplifying the process by which art is evolves and is made new.

This study was conducted to evaluate the effect of transfer temperature of epididymis on survival rate of semen and development ability of B6D2F1 mice embryos. No significant differences were noted in the survival rate of semen (59.0% ± 0.1 vs. 47.6% ± 0.1), in vitro fertilization rate (90.7% ± 0.1 vs. 90.7% ± 0.1), developmental rate (90.0% ± 0.1 vs. 90.0% ± 0.1), and blastocysts formation rate (53.1% ± 0.2 vs. 52.3% ± 0.2) between groups. (NS; P>0.05). However, the zona hatched rate was significantly higher in the 4°C group compared to those of the 37°C group (47.8% ± 0.1 vs. 25.6% ± 0.2; p<0.05). When it comes to cell numbers of blastocysts, the % ICM (/total cells) was significantly higher in the group of 4°C compared to the 37°C (27.0% ± 0.1 vs. 18.3% ± 0.1; p<0.05). However there were no differences in total cell numbers (72.7 ± 31.6 vs. 62.0 ± 36.6), ICM cell numbers (17.0 ± 7.8 vs. 14.6 ± 8.6), TE cell numbers (55.8 ± 29.8 vs. 64.0 ± 24.4), the ratio of ICM:TE (1:4.2 ± 4.1 vs. 1:6.4 ± 7.2) between two groups (NS; P>0.05).Taken altogether, it is expected to achieve the best developmental ability of B6D2F1 mice embryos in the transfer temperature of epididymis. Also these results can provide fundamental data to maximize culture condition for in vitro fertilization on B6D2F1 mice. In future, therefore, it is expected that results herein might be applied for in vitro culture of human embryos.

미 연방 제2순회 항소법원은 2012년 10월에 중요한 내부자거래 판결 인 오부스(SEC v. Obus) 판결을 내렸는데, 그 판결은 내부자거래 요건 을 명확하게 제시하고 있다. 그리고 내부자를 기소하기 위하여는 개인적 이득에 관한 입증이 요구되는데도 불구하고 법원은 정보가 부당하게 공 개되었다거나 혹은 내부 정보원이 개인적 이득과 교환으로 정보를 제공 하였다는 것을 실제로 알지 못할 수도 있는 정보수령자에 대하여 잠재적 책임의 범위를 확대하였다. SEC는 지이(GE) 캐피털의 직원 토마스 스트릭랜드(Strickland), 그리 고 윈필드(Wynnefield) 캐피털의 직원 두 사람 피터 블랙(Black)과 넬 선 오부스(Obus)에 대하여 내부자거래 위반으로 기소하였다. SEC는 스 트릭랜드가 자신의 대학 친구인 블랙에게 지이 캐피털이 자금을 대출해 주고 있던 얼라이드(Allied) 캐피털 회사가 선소스(SunSource) 회사를 인수할 가능성에 관하여 정보를 전달하였다고 주장하였다. 블랙은 차례 로 이 정보를 오부스에게 넘겼고, 오부스는 그 정보를 토대로 선소스 주 식을 거래하였다는 혐의를 받았다. 미 연방 뉴욕 남부지방 지방법원이 피고인에 유리한 약식재판을 승인 하였고, SEC는 부정유용이론의 관점에서 항소하였다. 제2순회 항소법원 은 SEC가 제시한 증거는 각 피고인의 책임에 관한 중요한 사실에 관한 진정한 논쟁을 제기하며, 따라서 약식재판은 잘못되었다고 판결하였다. 그리하여 항소법원은 그 판결을 파기 환송하였다. 이 판결에서 그 항소 법원은 (1) 정보전달자와 정보수령자의 책임의 요소들을 분명하게 하였 고, (2) 양 정보전달자와 정보수령자의 고의 요건에 관하여 완화된 견해 를 채택하였고, (3) SEC는 정보전달자가 내부자거래의 부정유용이론과 전통적이론 두 이론에서 개인적 이득을 받았다는 것을 입증하여야 한다 고 판결하였고, 그러나 이것은 SEC가 입증하기에 어려운 요소는 아니라 는 것을 경고하였으며, (4) 내부정보원이 개인적 이익을 받았다는 것을 정보수령자가 알지 못하고 책임을 부담할 수 있는지 여부의 문제에 대하 여는 미해결 상태로 남겨놓았다.

The external R&D, which includes the adoption of the external technology and knowledge in addition to the internal R&D, is one of important factors for the innovation. Especially for small and medium-sized enterprises (SMEs), the external R&D has been considered as a key factor to carry out the innovation more efficiently due to the limitations of their resources and capacities. However, most of extant studies related to external R&D have focused on analyzing the influence of external R&D on innovation outputs or outcomes. Only a few studies have explored the impact of external R&D on the innovation efficiency. This study therefore investigates whether the external R&D effects the industry’s innovation efficiency and productivity. On this study, we used Korean manufacturing industry data of SMEs from 2012 to 2014 and employed a global Malmquist productivity analysis technique, which is based on the Data Envelopment Analysis (DEA), to assess the innovation efficiency and productivity. Innovation performances of external R&D group and internal R&D group are compared. Then, the sectoral patterns of both innovation efficiency and productivity are analyzed with respect to the technological intensity, which is introduced by OECD. The results show that the gap of innovation efficiency between external and internal R&D groups has gradually decreased because of the continuous improvement of the external R&D group’s performance, while the external R&D group lag behind the internal R&D group. In addition, patterns of the innovation efficiency and productivity change were different depending on the technological intensity, which means that the higher the technological intensity, the greater the effect of external R&D.

목 적 : 최근 관상동맥 경화반(coronary plaque)을 진단하기 위해 X-ray를 이용한 관상동맥 조영술(coronary angiography), fractional flow wire를 통한 관상동맥 혈류측정 (fractional flow reserve, FFR),혈관내초음파(intravascular ultrasound. IVUS), 심혈관 광간섭 단층촬영(optical coherence tomography, OCT) 등 여러 가지 기법들이 사용되고 있다. 이 중 관상동맥 경화반(coronary plaque) 을 평가할 수 있는 PC-VENC를 이용한 MR- FFR(fractional flow reserve)이 개발되어 기존의 비침습적 영상기법인 관상동맥 CT와 OCT, FFR등 침습적 영상기법과 비교하여 연구가 진행되고 있다. 이에 본 연구는 관상동맥 경화반(coronary plaque)을 평가하는 MR-FFR 검사에서 사용되는 2D PC-VENC 기법의 최적화 요인에 대하여 알아보고자 한다. 대상 및 방법 : 2015년 8월부터 2016년 1월까지 관상동맥의 근위부에 의미 있는 동맥경화반이 관찰되어 침습적 관상동맥 조영술과 OCT 또는 FFR측정이 예정된 환자 30명을 대상으로 MR-FFR 검사를 진행하였다. 3.0T MR(Trio, Siemens Healthcare, Erlangen, Germany) 장비를 사용하였다. 코일은 phased-array body coil을 사용하였고 parameter는 fat saturation을 사용하고 in-plane resolution은 0.5-0.6 × 0.5-0.6 mm², slice thickness 는 3.2 mm, VENC 범위는 동맥 경화반 상태에 따라 40-80 cm/s(3방향 z, x, y), cardiac phases는 2 (segments/phase), scan time은 slice당 4-8min/slice으로 설정하였다. 결 과 : Stenosis 정도 40%이하는 4명(13%), 40~70% 에서는 25명(77%), 70%이상은 3명(10%)으로 검사하였다. 40%이하에서의 VENC측정값은 normal 구간에서 40cm/sec, plaque 구간에서는 41±2.5cm/sec로 나타났고, 40~70%에서의 VENC측정값은 normal에서 40cm/sec, plaque구간에서는 46±4.6cm/sec로 70%이상에서의 VENC 측정값은 normal, plaque구간 모두 45cm/sec로 나타났다. VENC측정값 별 평균 검사시간은 35~40cm/sec에서 91.2분, VENC 40~45cm/sec에서 98.4분, VENC 45~50cm/sec에서 98.4분, VENC 50cm/sec 이상에서 107분이 소요되었다. 결 론 : 관상동맥 경화반 진단을 위한 2D PC-VENC 기법 사용 시, 본 연구에서 측정된 stenosis 정도에 따라 적정 VENC측정값을 사용하여 장시간의 검사시간 낭비를 최소화 할 수 있다. 또한 미리 알고 있는 stenosis정보를 통해 guide가 될 수 있는 VENC값을 사용함으로써 검사시간의 효율화를 구현할 수 있다.

목 적 : 2014년 우리나라의 3대 사망원인 중 하나는 뇌혈관 질환이다. 그 중 큰 비중을 차지하고 있는 뇌혈관 폐색은 venogram으로 진단을 할 수 있다. venogram은 크게 PC기법과 TOF기법으로 나뉘는데 우리는 TOF기법에 대해 연구해 보았다. 2D TOF-MRA는 검사방향과 혈류의 방향이 같을 경우 계속되는 RF pulse의 영향으로 혈액 내 spin들이 포화되어 혈류신호가 감쇄하게 된다. 그래서 2D TOF-MRA검사시 oblique angle을 주고 검사를 진행한다. 이에 본 연구에서는 oblique angle의 유용성을 평가하고자 angle을 0°, 10°, 20°로 변화시켜 가며 각각의 영상을 비교 분석하여 보았다. 대상 및 방법 : 2015년 5월부터 2015년 10월까지 본원 내원해 Brain MRI을 시행한 환자중 뇌에 질병이 없는 30명(남성12명, 여성18, 연령분포 20~55세, 평균연령 35세)을 대상으로 하였다. 사용된 장비는 Skyra 3T(Siemens, Germany)이고 신호수집은 20 channel Head/Neck coil을 사용하였다. TR은 19ms, Thickness는 2.5mm, Matrix는 256×256, TE는 4.56ms, Bandwidth는 219kHz으로 설정하여 사용하였다. axial 단면에서 oblique angle을 0°, 10°, 20°로 주면서 sagittal단면으로 영상을 획득하였다. 결과 분석은 정량적과 정성적 두 가지로 하였다. 정량적 분석은 검사 후 얻은 영상에 세 곳을 정해 SNR을 측정하여 비교하였다. 정성적 분석은 영상의학과 전문의 1명과 전공의 1명 그리고 방사선사 1명이 3가지 평가항목에 대하여 Likert’s 5-point scale로 분석을 하였다. 통계분석은 SPSS 19K를 사용하였다. 결 과 : 정량적 분석의 결과 SSS의 SNR측정치 평균값은 0°-27.4155, 10°-35.4500, 20°- 44.3650으로 각도가 커질수록 SNR값도 증가 되었다. 다중비교결과 세 경우 모두 유의확률이 0.05이하로 각각의 값들이 유의한 차이를 보였다. SSC의 SNR측정치 평균값은 0°-16.6900, 10°-20.2600, 20°-26.6405으로 각도가 커질수록 SNR값도 증가 되었다. 다중비교결과 0°와10°는 0.05이상으로 차이가 없었고, 20°만 0.05이하로 유의한 차이를 보였다. DTS의 SNR측정치 평균값은 0°-82.3150, 10°-86.2850, 20°-92.5200으로 각도가 커질수록 SNR값도 증가 되었다. 하지만 다중비교결과 세 경우 모두 유의확률이 0.05이상으로 각각의 값들이 유의한 차이를 보이지 않았다. 정성적 분석의 결과 SSS는 평가자 1,2,3이 모두 각도가 커질수록 점수가 증가 되었다. 유의확률은 각각의 다중비교 결과 1,3은 유의확률이 모두 0.017이하로 유의한 차이를 보였으나 2만 10°-20°간에 유의한 차이를 보이지 않았다. SSC는 평가자 1,2,3이 모두 각도가 커질수록 점수가 증가 되었다. 유의확률은 각각의 다중비교 결과 1,3은 유의확률이 모두 0.017이하로 유의한 차이를 보였으나, 2만 0°-10°간에 유의한 차이를 보이지 않았다. DTS는 평가자 1,3은 모든값이 같게 나왔고 2만 각도가 커질수록 점수가 증가 되었다. 유의확률은 각각의 다중비교 결과 세 경우 모두 0.017이상으로 유의한 차이를 보이지 않았다. 결 론 : 정량적 분석과 정성적 분석 모두에서 대체적으로 각도가 커질수록 영상의 질이 좋아짐을 알 수 있었다. 각도의 변화는 숙련 기간이 필요하지도 않고 특별히 재구성하는 것도 없었으며 검사 시간도 늘어나지 않는다. 뿐만 아니라 검사 영상의 화질도 더 좋아진다. 그러므로 각도를 기존보다 더 크게 20° 주는 방법은 유용한 검사법이라 사료된다.

Stress on plates may increase in the neighborhood the edges or the holes for rivets or bolts. Excessive stress concentration may lead to severe breakage of the plates. Thus, it is important to conduct optimization of arrangement of holes at the design stage. In this paper, accuracy of FEM analysis was examined for such stress concentration . By changing the hole size on a narrow plate, change of the stress concentration factor(K) was investigated. Additionally, the same experiment was conducted about series of multiple holes on plate to investigate interaction between the adjacent holes. Then, the FEM results were compared to the reference predictions respectively. Finally, a method by which simple stress concentrating situations can be optimized, will be suggested. This method was examined by FEM, and showed similar tendency with the expectation. Therefore, this method can be valuable when arranging the holes on a plate.

Exposure to house dust mites is closely connected with allergic diseases such as atopic dermatitis, allergic rhinitis, and asthma. House dust mites (Dermatophagoides farinae and D. pteronyssinus) act as allergens even after their death. Therefore, repelling the house dust mites is more effective method than killing them. Many chemical agents have been used in killing house dust mite. However, it is usually reported that these chemical agents (acaricides) exhibit adverse effects and toxicity toward animals and human. For these reasons, we carried out the experiments for measuring the repellent activity of Mate tea and Jasmine tea against house dust mites in this experiment. In order to determine the concentration having the most effective repellent effect of Mate and Jasmine tea, house dust mites (D. farinae and D. pteronyssinus) were exposed at different concentrations (0, 0.015625, 0.03125, 0.0625, 0.125, 0.25, 0.5 mg/40 μL) of Mate tea and Jasmine tea extracts, respectively, for different hours (0.5, 1, 2, 3 hours). The most effective repellent effect (%) against house dust mite in 0.25 mg/40 μL of Mate tea for 2 hours was 73.5%, Jasmine Petal tea in 0.0625 mg/40 μL for 1 hour was 84.1% and Pearl Jasmine tea in 0.125 mg/40 μL for 0.5 hour was 82.8%. These results suggest that Mate tea and Jasmine tea extracts have potential effect to repel the house dust mites (D. farinae and D. pteronyssinus)

Early pregnancy results in th production of various signal molecules such as steroids, prostaglandins, and many protein factors. The proteins especially produced by the placenta have been used to detect pregnancy for many years in other species. More recently, pregnancy-specific protein B, which is a placental glycoprotein can be measured by RIA or proteomic methods in serum of pregnant cow. And 2D Fluorescence difference gel electrophoresis (DIGE) is an emerging technique for comparative proteomics, which improves the reproducibility and reliability of differential protein expression analysis between samples. For this reason, we are analyzed serum of bovine. The purpose of this study was to apply DIGE technique for identification of bovine pregnancy-specific proteins using bovine pregnant and non-pregnant serum samples. Serums of 2 pregnant Holstein dairy cattle at day 21 after AI and those of 2 non-pregnant were used in this study. The molecular weight and charge matched cyanine dyes enable pre-electrophoretic labeling of non-pregnancy and pregnant serum proteins which are then mixed and labeled with Cy2 were used as an internal standard. Two pools of proteins are labeled with Cy3 and Cy5 fluorescent dyes, respectively. Labeled proteins with Cy2, Cy3 and Cy5 mixed together and separated in same gel and then were detected by fluorescence image analyzer. The 2D DIGE analysis using fluorescence CyDye flour showed higher sensitivity and better reproducible results than conventional 2D gel electrophoresis. Approximately 1,500 protein spots were detected by 2D DIGE. The differentially expressed proteins were identified by MALDI-TOF Mass spectrometer. Total 16 protein spots differentially expressed in the pregnant serum were detected, among which 7 spots were up-regulated proteins identified as conglutinin precursor, modified bovine fibrinogen, IgG1 etc, and 6 spots were down-regulated proteins identified as hemoglobin, complement component 3, bovine fibrinogen, IgG2a etc. These results indicated that DIGE system could be advantageous for the analysis of serum proteomics diversified by physiological conditions.

The genus Saissetia Deplanche is newly reported from Laos, including two new species, Saissetia simulocoffeae Choi & Lee, sp. n. and S. quasioleae Choi & Lee sp. n., and a first record of S. miranda (Cockerell & Parrott, 1899). A key to all five species of Saissetia known from Indochina is provided. The DNA barcodes (mitochondrial cytochrome oxidase subunit I-mtCOI) of the two new species were obtained for future use.

The essential oils of three Coriandrum sativum seeds cultivated from India, Russia and America were evaluated for acaricidal toxicities against Dermatophagoides farinae, D. pteronyssinus, and Tyrophagus putrescentiae. The oils of three C. sativum seeds were analyzed by gas chromatography. The oil of C. sativum seeds cultivated from India included substantially linalool (66.8%) and camphor (6.46%). In the fumigant bioassay, based on the LD50 values against D. farinae, D. pteronyssinus, and T. putrescentiae, the oil of C. sativum seeds cultivated from America (LD50, 2.62, 2.74, and 2.88 μg/cm3) was about 3.75, 3.32, and 4.17 times more active higher than benzyl benzoate (9.85, 9.10 and, 12.01 μg/cm3). The acaricidal activity of the oil of C. sativum seeds cultivated from India was 2.27, 2.03, and 2.64 times higher than that of the benzyl benzoate, followed by Russia oil. These results suggest that the oils of three C. sativum seeds might be used as suitable acaricides.

Microstructure evolutions of thermosetting resin coating layers fabricated by electrostatic spray deposition (ESD) at various processing conditions were investigated. Two different typical polymer systems, a thermosetting phenol-formaldehyde resin and a thermoplastic polyvinylpyrrolidone (PVP), were employed for a comparative study. Precursor solutions of the phenol-formaldehyde resin and of the PVP were electro-sprayed on heated silicon substrates. Fundamental differences in the thermomechanical properties of the polymers resulted in distinct ways of microstructure evolution of the electro-sprayed polymer films. For the thermosetting polymer, phenol-formaldehyde resin, vertically aligned micro-rod structures developed when it was deposited by ESD under controlled processing conditions. Through extensive microstructure and thermal analyses, it was found that the vertically aligned micro-rod structures of phenol-formaldehyde resin were formed as a result of the rheological behavior of the thermosetting phenol-formaldehyde resin and the preferential landing phenomenon of the ESD method.

There is a growing interest in the application of primary hepatocytes for treatment of liver diseases in humans and for drug development. Several studies have focused on long-term survival and di-differentiation blocking of primary hepatocytes in an in vitro culture system. Therefore, the present study also aimed to optimize an in vitro culture system using primary rat hepatocytes. Primary rat hepatocytes from 6-week-old male Crl:CD rats were isolated using a modified two-step collagenase perfusion. Healthy 3.5 × 106 primary rat hepatocytes were seeded into a 2 dimensional (2D) culture in a 25T culture flask coated with collagen type I or into a 3D culture in a 125-ml spinner flask for 7 days. Production of plasma protein (ALB and TF), apoptosis (BAX and BCL2), and CYP (CYP3A1) related genes were compared between the 2D and 3D culture systems. The 3D culture system had an advantage over the 2D system because of the relatively high expression of ALB and low expression of BAX in the 3D system. However, the level of CYP3A1 did not improve in the 3D culture with and without the presence of a dexamethasone inducer. Therefore, 3D culture has an advantage for albumin production and primary rat hepatocyte survivability, but a low expression of CYP3A1 indicated that primary rat hepatocytes require a high–density culture for stress reduction by continuous flow.

Although should implies obligation or necessity and would indicates undecided desire or intention, the phrases would/ʹd like to and should like to do not differ semantically, except that should like to is used in written British style. This paper investigates the two expressions synchronically and diachronically in corpora, namely the COHA, COCA, GloWbE, BYU‐BNC, and BNCweb. Historically, should like to was more frequent before the 1850s, but has almost disappeared from American English in the 20th and 21st centuries. Following American English, should like to has almost perished in the Inner, Outer and Expanding Circles of English. It was overtaken by would/ʹd like to, which flourished until the 1970s, and has subsequently decreased in use, despite remaining common in contemporary English. Filling the gap, would/ʹd love to has increased in use over time. The paper discusses would/ʹd love to as a popular expression in the future.