Oral squamous papilloma (OSP) is a common benign lesion of the oral mucosa that is induced by the human papillomavirus. To investigate the clinicopathological characteristics of OSP, we selected 135 patients diagnosed at the Seoul National University Dental Hospital. OSPs occurring in Koreans had a slight female predilection, with the male to female ratio being 1:1.6. The age ranged from 4 to 80 years old (average age: 47 years). The most frequent location was the soft palate (43.7%), followed by the tongue and gingiva. 11.1% of all patients presented with pain. There have been no reported cases of recurrence. On microscopic examination, two‐thirds of the lesions were parakeratinized, with almost all cases (99%) containing the koilocytes. In conclusion, there were no significant differences between the clinicopathological features of OSP in Korean and findings from previous studies

Saliva from the oral cavity was collected from 129 patients with periodontitis and 54 Staphylococcus aureus isolates were isolated from these samples. The S. aureus isolates were tested for their resistance patterns against 15 antibiotics using the disc diffusion method. The percentage of S. aureus isolates resistant to ampicillin was the highest (92.6%). In addition, the percentage of S. aureus isolates resistant to penicillin, oxacillin, cefotetan, cefepime and erythromycin was 90.7%, 11.1%, 11.1%, 9.3% and 5.6%, respectively. However, S. aureus isolates were susceptible to gentamycin, clindamycin, trimethoprim/sulfamethoxazole and vancomycin. 96.3% of S. aureus isolates were resistant to antibiotics. Among them, the percentage of two antibiotic-resistant S. aureus isolates was 74.1%, the percentage of one antibiotic-resistant S. aureus isolates was 5.6%, the percentage of three antibiotic-resistant S. aureus isolates was 3.7% and the percentage of S. aureus isolates resistant to more than 4 antibiotics was 13%. The most common multiple antimicrobial resistance pattern was AM-P. Furthermore, the percentage of methicillin-resistant S. aureus isolates was 11.1% and they were resistant to more than 3 antibiotics.

목적: 20~71세 성인을 연령에 따라 5군으로 분류하여 연령에 따른 한국인의 고위수차 변화도를 알아보기 위하여 수행되었다. 방 법: 본 연구의취지에 동의한 사람가운데 전신질환이나 안질환이 없으며, 굴절이상 수술을 포함하여 안과 관련 수술병력이 없는 성인 290안을 대상으로 Pentacam을 사용하여 동공직경 5mm 범위에서의 총고위수차(HOA), 총구면수차(TSA), 총코마수차(TCA), 총트레포일수차(TTA)를 측정하였다. 결과: 전체 대상군의 전면 HOA의 Root-mean square(RMS)에 대한 평균값은 0.094±0.021㎛, 후면 HOA의 RMS에 대한 평균값은 0.022±0.004㎛ 이고, 전체 HOA의 RMS에 대한 평균값은 0.080±0.022㎛로 나타났다. 연령에 따른 HOA의 상관관계를 분석한 결과 전면수차는 연령과 유의한 상관관계(r=0.335, p < 0.0001)를 보였지만, 후면과는 유의한 상관관계(r=0.096, p=0.102)가 없는 것으로 나타났다. 전체 대상군의 전면 TSA의 RMS에 대한 평균값은 0.279±0.057㎛, 후면 TSA의 RMS에 대한 평균값은 0.057±0.017㎛ 이고, 전체 TSA의 RMS에 대한 평균값은 0.223±0.056㎛ 로 나타났다. 연령에 따른TSA의 상관관계를 분석한 결과 전면수차는 연령과 유의한 양의 상관관계(r=0.240, p < 0.0001)를 보였지만, 후면과는 유의한 음의 상관관계(r=-0.358, p < 0.0001)를 보였다. 전체 대상군의 전면 TCA의 RMS에 대한 평균값은 0.089±0.046㎛, 후면 TCA의 RMS에 대한 평균값은 0.024±0.012㎛ 이고, 전체 TCA의 RMS에 대한 평균값은 0.081±0.045㎛로 나타났다. 연령에 따른 TCA의 상관관계를 분석한 결과 전면수차는 연령과 유의한 양의 상관관계(r=0.118, p=0.04)를 보였고, 후면 또한 유의한 양의 상관관계(r=0.311, p < 0.0001)가 나타났다. 전체 대상군의 전면 TTA의 RMS에 대한 평균값은 0.042±0.035㎛, 후면 TTA의RMS에 대한 평균값은0.012±0.008㎛ 이고, 전체TTA의RMS에 대한평균값은0.041±0.032㎛로 나타났다. 연령에 따른 TTA의 상관관계를 분석한 결과 전면수차는 연령과 유의한 양의 상관관계(r=0.250, p < 0.0001)를 보였고, 후면 또한 유의한 양의 상관관계(r=0.149, p=0.011)가 나타났다. 결론: 한국인의 각막 고위수차 분석을 통하여 한국인 눈의 광학적 부분의 더 나은 이해를 제시하였으며, 현대인의 시력의 질을 향상시키기 위한 추가적인 연구에 활용될 수 있는 기초 자료로 활용 할 수 있을 것으로 사료된다.

Sialolithiasis consists of calcified structures in either the salivary gland or ductal system and alteration of salivary gland parenchyma. To investigate the clinicopathological features of sialolithiasis in Korean patients, we selected 60 patients with sialolithiasis diagnosed at the Seoul National University Dental Hospital. Their clinical records and radiographs were reviewed with the analysis of available histologic data from 32 cases. The male to female ratio was 1.1:1. Sialolithiasis is most common between the ages of 20 and 60 years and occurred most frequently in the submandibular gland (97%). Upon microscopic examination, most lesions showed moderate-to-severe inflammatory infiltration and parenchymal changes such as ductal metaplasia, acinar necrosis and fibrosis. Consequently, Korean patients exhibited clinicopathological features similar to those previously reported.

목 적: 본 연구는 한국인의 백내장과 녹내장의 유병률에 대해 알아 보고자 하였다. 방 법: 백내장과 녹내장의 유병률은 2007년도 국민건강영양조사 자료에서 30세 이상의 2,643명(남성: 1,101명, 여성: 1,543명)을 대상으로 하였다. 본 연구는 서베이분석법인 PROC SURVEYFREQ를 사용하여 사회경제적 위험요인과의 관계에 따른 유병률의 변화를 보았다. 모든 통계분석은 SAS 9.2 통계패키지를 사용하였으며, 유의성 검정은 0.05 이하로 하였다. 결 과: 2007년도 한국인은 3.0%(남성 9.8%, 여성 4.6%)가 백내장을 가지고 있었고, 7.8%(남성 5.7%, 여성 9.8%)가 백내장을 앓은 경험이 있었다. 녹내장 유병률과 경험률은 각각 0.2% (남성 0.4%, 여성 0.2%)와 0.5% (남성: 0.5%, 여성 0.4%)이었다. 65세 이상 남성 노인에서, 백내장 경험률 및 유병률은 19.9%와 4.1%이었으며, 여성에서는 38.3%와 17.2% 이었다. 그러나 30-64세 사이의 젊은 사람들에게 백내장 경험과 유병률이 남성에서 3.4%와 0.8%이었으며, 여성에서 1.6%와 3.0%이었다. 65세 이상 노인에서, 녹내장 경험률과 유병률은 남성에서 1.6%와 1.1%이었으며, 여성에서는 1.6%와 0.8%이었다. 젊은 사람들에게서 녹내장의 경험률과 유병률은 남성에서 0.3%와 0.1%이었으며, 여성에서는 모두 0.1% 이었다. 또한, 교육수준이나 소득이 낮은 경우, 비경제인구이거나 실업자의 경우 백내장과 녹내장의 유병률과 경험률이 높았다. 결 론: 30세 이상의 한국인에서 백내장의 유병률은 3.0%, 녹내장의 유병률은 0.2%였다. 본 연구결과는 한국인에서 안보건과 안질환의 적절한 건강관리 정책을 만드는데 있어 중요한 결과라고 할 수 있다.

In this study, the representative hand shapes for the adult Koreans were analyzed by factor analysis and cluster analyses. The analyses were conducted on the anthropometric data of 58 hand dimensions from 325 subjects having nonhomogeneous demographics. Maximum hand circumference, first phalanx length of index finger, and ratio between the two measures were the independent variables for the cluster analyses. The results of the study showed that Korean hand shapes can be divided into 2 clusters irrespective of their size for each of the male and female group. There were slight differences in component ratio of hand shapes with respect to the occupation and the age, but their differences were not statistically significant. The representative Korean hand shapes and their anthrpometric dimensions could be used to design and establish proper sizing system for various hand operating devices.

본 연구는 디자인 요소로 한글을 사용하려 할 때 다양한 한글글꼴에 대한 감성과 선호도에 대한 객관적 정보 제공하여 한글글꼴 사용에 있어서의 방향 제시를 돕고자 하는 목표를 가지고 있다. 연구의 세부 목표는 첫째, 한글글꼴의 조형 요소를 좀 더 객관적으로 분석하기 위해서 한글을 전혀 모르는 중국인을 대상으로 한글글꼴에 대한 감성 차이가 한국인하고 어느 정도 차이가 있는지 분석하였다. 둘째, 글꼴에 대하여 한국인과 중국인들의 선호 비선호를 비교 분석 하였다. 첫 번째 목표를 밝히기 위해 요인 분석을 실시한 결과, 한국인과 중국인이 모두 2가지 대표요인으로 [친숙성], [soft]가 추출되었으며 양국 모두 제 1요인과 제2요인의 소속요인 모두가 순위의 차이는 있었지만 대다수가 공통적으로 가지고 있어 한국인과 중국인들이 한글글꼴에 대하여 서로 비슷한 감성을 가지고 있음을 알 수 있다. 두 번째 한글글꼴 선호도 분석을 실시한 결과, 한국인 및 중국인의 선호도를 결정하는 가장 큰 요인은 친숙성이라고 볼 수 있고, 한글을 전혀 모르는 중국인들 또한 중국문화에 애용하여 왔던 붓글씨적인 서체를 선호하는 경향이 있었다.

An individual's food-related personal traits play an important role in influencing personal food choice and habits. According to culture, their influence can manifest differently. To ascertain personal traits about food, FNS (food neophobia scale) and FIS (food involvement scale) were employed in recent studies. This study aimed to understand the food culture and food choices of East-South Asians who live or stay in Korea through comparison of FNS and FIS. Eighty Koreans and 233 East-south Asians (Indonesians, Filipinos, Malaysians, Vietnamese, Thai, Singaporeans, and Bangladeshi) completed a questionnaire to measure FNS (10 questions), FIS (12 questions), and sociodemographic conditions (9 questions). ANOVA was conducted to ascertain FNS and FIS between the groups, and regression analysis was carried out to determine which sociodemographic factors had an effect. The items were analyzed to determine the differences according to gender, age, marital status, nationality, religion, occupation, educational background, monthly income, and length of residence in Korea. FNS showed significant differences between the groups with regard to sociodemographic characteristics, except gender, age, and marital status, whereas FIS showed significant differences in gender, nationality, religion, occupation, educational background, monthly income, and length of residence in Korea. The results of the regression analysis suggest that nationality strongly affected FNS and FIS, and FIS was also affected by gender.

Runt-related transcription factor (RUNX) 3 is well known as a developmental regulators, as well as candidate tumor suppressor gene in human breast cancer, gastric cancer, esophageal cancer, and so on. The present study was aimed to analyze the expression of RUNX3 protein in oral squamous cell carcinoma (OSCC) from Korean patients. The immunohistochemical stain was performed with 14 normal oral mucosa (NOM) and 25 OSCCs, and statistical analysis was carried out to find out the correlation between the expression of RUNX and clinicopathological parameters of OSCC patients. In OSCC, the expression of RUNX3 protein was found to increase more than in NOM. Moreover, in the univariate correlation analysis, the gender, regional lymph node metastasis, and histopathologic differentiation of OSCC patients were positively correlated with the expression of RUNX3 (p<0.05). These results indicate that RUNX3 can play a role as an oncogene in OSCC, in contrast to some reports on RUNX3 in other human cancers. In addition, RUNX3 may be considered as new malignant biomarker of OSCC.

A continuing challenge for English educators and policy makers in Korea is how to provide the right amount of good English education in an effective and efficient way, to help achieve the needed level of English communication skills. No efforts would turn out successful if the amount and the quality of public English education did not meet people's expectations. In order to plan and implement successful English education policies, it is necessary to figure out what kind of English education and how much of it are needed for Korean people. The current study aims to investigate what levels of English speaking proficiency Korean people perceive they need. The study first reviews some widely-used international English oral proficiency standards, then, compares those with the level descriptions of the Korea’s national curriculum of English. To gather information on the current level of English speaking proficiency, and the expected level of English speaking proficiency, 356 teachers (123 elementary school, 114 middle school, 119 high school), 696 students (179 elementary school, 222 middle school, 295 high school), and 650 parents (164 elementary, 212 middle school, 274 high school) from all the 16 district education authorities, were surveyed and interviewed. The results are presented with the discussion of the future directions of English education in Korea.

Oral squamous cell carcinoma (OSCC) is the most common cancer of oral cancers. Recent data suggest that chemokines could be essential players in carcinogenesis and that tumor cells express chemokine receptors and use chemokines to metastasize to the target organ in many malignancies in humans. The aim of this study was to test the hypothesis that expression of SNPs in chemokine, CXCL1 and CXCL2 correlates with oral squamous cell carcinomas in Korean population. The CXCL1 and CXCL2 genotypes were determined in 21 subjects with oral squamous cell carcinoma and 90 control subjects without oral squamous cell carcinoma. The genotypes were determined by direct sequencing. The genotype distribution and allele frequency within the OSCC patients were not significantly different from those of control subjects. But among OSCC subjects, there was significant difference of CXCL1 gene in the degree of nuclear aberration. These findings suggest that CXCL1 -442C/T polymorphism and CXCL2 -264T/C polymorphism are not related to the development of OSCC but polymorphism of CXCL1 gene might have a relation with progression of OSCC in Korean population.

It is presumable that properly designed earcons given simultaneously with visual information could enhance the situation awareness of operators when they are involving in highly complicate process control activities. In this study, population stereotypes of earcons with respect to process control information were identified using 60 Korean subjects. To do this, 11 most distinctive earcons were selected from various earcons having different pitch, rhythm, and timbre. Associations between the selected earcons and 40 pairs of adjectives used to describe the state of control in process were gathered from 37 subjects using a semantic differential method. Based on the results from multivariate analyses, the 40 pairs of adjectives were aggregated into three distinctive semantic dimensions. The emotional maps of the 11 earcons matched with the semantic dimensions were presented in this study. On the basis of these results, a general guideline was suggested for designing earcons to deliver process control information.

The incidence of multidrug-resistant strains of Staphylococcus aureus continues to increase in hospitals and the community all over the world. As the importance of miner surgery in dentistry gets greater recently, the frequency in use of antibiotics has been increasing. Although several cases of acquired infection in oral cavity in dental hospital has been reported, the research on isolation of S. aureus and evaluation of its antibiotic resistance from outpatients in the dental clinic has not been found yet. The aim of this study was to evaluate the antimicrobial resistance of S. aureus isolates. The isolation rate of S. aureus were 41.7% in dental hospital personnel, 60.4% in outpatients and 62% in dental hygiene students. S. aureus which showed resistance to penicillin were 88.6%, ampicillin 88.6%, erythromycin 8.6%, tetracycline 4.3%, oxacillin 4.3%, cefoteten 4.3%. Six strains of S. aureus showed the susceptible to all antibiotics tested. Sixty-four(91.4%) strains were multiple antibiotic resistance. Fifty-two strains(72.8%) resisted to AM-P. and Seven strains(10.0%) resisted to AM-P-E, AM-P-GM, AM-P-TE.

The fundamental purpose of this study is to investigate the degree of correlation between the receptive and speaking skills by comparing the scores of the TOEIC (the Test of English for International Communication) and the ESPT (the English Speaking Proficiency Test). A recent research (Cunningham: 2002) shows that gaining scores on the TOEIC do not affect much improvement of communication skills. In this study, two instruments were used to collect data: the TOEIC and the ESPT. These two tests were administered to freshmen at one of the universities at Kyungsang Province. On the basis of the TOEIC scores the participants got, they were divided into two groups: intermediate and basic. The results show that the overall correlation coefficient between the TOEIC scores and the ESPT test for all was 0.51. However, the correlation coefficient between these two test scores for the intermediate level was as low as 0.43 and the basic level 0.25. This study implies that interpreting the correlation between receptive and speaking skills should be cautious.

The mask-face interface design should consider the face shape to improve the half mask respirator's fit ratio. This study tried to design the mask-face interface using recent Korean face data. By using the data of 1536 men's 3D face scanning (Size Korea data), head clay mock-up was made and mask-face interface line was extracted from this head mock-up. Using this interface line, the half-mask prototype was made. According to the quantitative fitting test, the proposed mask was found to be well fitted (average fit-ratio > 100). The proposed method had two advantages. 1) The method could use massive head-related anthropometric data like Size Korea data. 2) The qualitative fit test (observation) could be conducted very quickly by fitting the prototype to the head mock-up. However, this method also had several limitations. 1) The head clay mock-up could be different according to the mock-up maker. 2) The average values of the head-related anthropometric data were used to make the head mock-up. Small and large size head mock-ups should be made and tested.

과거에는 단순한 생리처리 및 위생공간이었던 욕실에 대한 기능이 현대에 들어서는 생활의 활력을 충전하고, 자신만의 욕구와 실현의 공간으로써 활용되는 다기능 공간화 되어 가고 있다. 이러한 의식주에 대한 소비자들의 새로운 욕구와 변화가 나타나면서 현재 '욕실' 공간에서의 행위와 요구사항을 파악할 필요성이 높아져 가고 있다. 많은 수의 한국인들은 욕실사용에 있어서 서양의 입식(立式) 샤워 방식 외에도 욕조 밖이나 대야 등에 물을 받아 사용하는 등의 욕실사용 행태를 나타내고 있다. 따라서 이와 같은 한국인의 독특한 욕실사용행태를 설계에 반영함으로써 한국인의 욕실문화가 고려된 욕실구조 도출이 가능할 것이다. 본 연구는 욕실공간에 대한 사용 만족도를 높이기 위해 한국인의 욕실사용 정황과 사용 중에 느끼는 불편함과 종합적 감정 등을 조사하여 욕실 사용자의 요구사항을 도출하며, 욕실 공간계획에 있어서 건강, 위생문제를 해결하는 공간이자, 현대인의 신체특징과 라이프스타일이 반영 가능한 기본적인 설계지침 도출을 연구목표로 하고 있다.

Ramyen and Korean noodles (guksu) are popular foods in Korea and around the world. Since 1998, rice consumption in Korea has gradually decreased, whereas consumption of noodles has continuously increased. The purpose of this study is to assess the consumption of ramyen and Korean noodles of Koreans, using data from the Korean National Health and Nutrition Examination Survey (KNHANES) of 2007. Korean adults (>20) were selected to examine the associations between noodle consumption and food and nutrient intake and health status. SAS 9.1 and SUDAAN 9.1 were used for the data analysis. 10.3% of Korean adults consumed ramyen, and 15.4% consumed Korean noodles. The consumption of ramyen and Korean noodles were higher in men than in women, in lunch than in other meals, and in the lowest income quartile than the highest quartile. Ramyen and Korean noodle consumer groups consumed more grain products, seasonings, and oils than the nonconsumer group. The noodle group showed significantly lower systolic blood pressure than the non-consumer group. The noodle groups showed lower rates of hypertension and metabolic syndrome than the non-consumer group. From these results, we conclude that ramyen and Korean noodles may have positive health effects. More studies on the association between noodles and the health of Koreans and those in other countries should be done in the future.

목적 : 이 연구는‘2004 생활시간조사’에서의 행동분류를 작업영역에 따라 분류한 후, 한국인의 생애주기별로 작 업영역에 따른 시간사용량을 비교하고자 하였다. 연구 방법 :‘2004 생활시간조사’의 원자료 중 12세 이상인 대상자 총 30,437명의 시간 사용량을 사용하였다. 생 애주기는 청소년초기, 청소년후기, 성인초기, 성인기, 노인기로 구분하였고, OTPF에 의한 작업영역으로 원자료의 행동을 재분류하여 분석하였다. 결과 : 모든 일과 수단적 일상생활활동은 성인기에, 교육은 청소년초기에 시간사용량이 높았고, 휴식 및 수면 시간 사용량은 노인기에 가장 높았다. 여가는 노년기의 시간사용량이 증가되었는데 야외활동 보다 실내 활동이 더 증가 되는 양상을 보였다. 성인기의 남자에게서는 일에서, 여자는 수단적 일상생활활동에서 시간사용량이 높았다. 결론 : 이 연구결과를 통하여 성별, 생애주기별 작업영역에서의 시간사용량에 차이가 있었음을 파악할 수 있었다. 그러므로 앞으로 작업치료에서 작업균형에 대한 작업치료 중재 시 비교자료로 활용이 가능하고, 생애주기와 남녀 차이에 따라 고려하는 것이 필요함을 알 수 있었다.