Laser can be used to precisely and locally modify the properties of superconductors. Their crystal structure and charge distribution can be altered by applying focused energy, thus affecting their microstructure and electrical properties. This technique enables the design and development of new materials with enhanced performance for various applications. This paper focuses on the effect of laser irradiation on the thermal, structural, and electrical properties of the Bi1.9Sb0.1Ba1.9Y0.1Ca2Cu3O10+δ superconducting compound. Samples were exposed to heat for 48 h at 900 °C at a heating rate of 10 °C/min. X-ray diffraction (XRD) studies were performed and the diffraction results showed that all samples had a regular orthorhombic crystalline structure and that the lattice constants (a, b, c) changed with irradiation compared to the unirradiated sample. A significant increase in the c/a axis, lattice size high-temperature phase (HTP) was also observed after irradiation. The content of the high-temperature phase increased to 81.47 %. The topographical nature of the samples was examined using scanning electron microscopy (SEM), and a change in the formation of nanosized grains was found in the samples. Using an energy-dispersive X-ray spectroscopy (EDX) device, elemental analysis was performed to detect the presence of different elements and determine their proportions in each sample. The critical temperature was also determined. The results showed that when the sample was exposed to radiation, the highest critical temperature was 114 K.

본 연구는 실시간 인간–컴퓨터 대화에서 가상 인물의 자연스러움과 감성적 공명(emotional resonance)을 향상시키 기 위한 음성 기반 복합 감성 디지털 휴먼 상호작용 프레임워크를 제안한다. 시스템은 먼저 음성 감성 인식(Speech Emotion Recognition, SER) 모듈을 통해 사용자의 음성으로부터 정서적 특징을 추출하고, 이후 GPT 기반 모델을 이용하여 세분화된 복합 감성 가중치 분석을 수행한다. 분석 결과는 JSON 형식으로 구조화되어 로컬 API를 통해 Unreal Engine 5 (UE5) 렌더링 환경으로 전달되며, 이를 통해 음성 파라미터를 MetaHuman 얼굴 동작 단위(Action Units, AUs)에 동적으로 매핑한다. 시스템의 효율성을 검증하기 위해, 총 40명의 참가자가 자연성 및 현실감, 복합 감성 표현의 효과성, 감성적 공명, 전체 상호작용 성능의 네 가지 지각적 차원을 평가하였다. 분석 결과, 모든 차원의 평균 점수가 중립 수준(3점)을 유의하게 상회하였으며(p<.001), Cronbach's α 값이 0.70을 초과하여 척도의 내부 일 관성이 양호함을 확인하였다. 또한, 효과 크기(Cohen’s d > 0.8)는 시스템이 감성 표현력과 상호작용 유창성에서 뚜 렷한 이점을 지님을 보여주었다. 종합적으로, 본 연구의 프레임워크는 음성 기반 복합 감성 생성을 통해 교차 모달 감성 전달(cross-modal emotional transmission)을 실현하며, 향후 감성컴퓨팅 및 디지털 휴먼 상호작용 연구를 위한 확장 가능한 기술적 경로를 제시한다.

This study investigated nutritional composition and bioactive properties of thinned Shinanogold apples to evaluate their potential as functional food and cosmetic ingredients. Thinned Shinanobold apples exhibited markedly higher vitamin C (16.22 mg/100 g), total phenolics (886.27 mg GAE/100g), and total flavonoids (31.54 mg QE/g) levels than mature apples. The antioxidant capacity, assessed using DPPH and ABTS radical scavenging assays, was significantly higher in thinned apples (74% and 72%, respectively) than in mature apples (48% and 52%, respectively). The tyrosinase inhibitory activity, which is important for melanin reduction, and α-glucosidase inhibitory activity, which play a role in delaying glucose absorption, were higher in thinned apples (67% and 70%, respectively) than in mature apples (X and X, respectively), suggesting potential use of thinned apples as skin-whitening and antidiabetic agents. Furthermore, lipoxygenase inhibitory activity was higher in thinned apples (52%) than in mature apples (42%), suggesting potential use of thinned apples as an anti-inflammatory agent. These findings demonstrate that thinned Shinanobold apples contain bioactive constituents with superior activities compared with mature fruits. In addition, these results highlight the potential use of thinned apples as functional food ingredients and cosmetic agents.

This study aimed to identify the optimal storage and germination conditions for producing sprouts from immature bulbils of the Korean garlic cultivar ‘Hongsan’. It also evaluated the effects of LED light quality on sprout growth and compared the functional compound contents across different plant parts. Germination trials indicated that storing bulbils at 4°C for at least 64 days, followed by germination at 10-20°C, yielded the best results. Under mixed LED light treatments (Red:Blue:White), a red-dominant ratio of 4:1:0 significantly enhanced both shoot and root elongation, while germination in darkness resulted in the highest fresh and dry weights. Among the plant parts, sprouted bulbils had the highest alliin content (3,711 mg/100 g) and contained greater levels of fructose and glucose compared to cloves. Conversely, cloves had the highest fructan content, and leaves exhibited the highest total polyphenol content. These findings underscore the importance of combining proper storage and light quality for efficient sprout production from bulbils and highlight the potential of sprouted bulbils as functional food materials.

This study optimized the extraction of β-carotene and antioxidant compounds from orange-fleshed sweet potato (Ipomoea batatas L.) using response surface methodology (RSM) with ethyl lactate as a green solvent. A central composite design (CCD) was utilized to evaluate how the solvent-to-sample ratio, temperature, and extraction time affected efficiency. The regression model was statistically significant (Adj. R2=0.67), revealing that the solvent-to-sample ratio was the most influential factor, while temperature and time had relatively minor effects. The optimal conditions identified were a ratio of 12 mL/g, a temperature of 35°C, and an extraction time of 30 minutes, which resulted in a yield of 27 mg/100g of β-carotene, along with high levels of polyphenols, flavonoids, and strong antioxidant activities as measured by DPPH (2,2-diphenyl-1-picrylhydrazyl) and ABTS (2,2'-azino-bis(3-ethylbenzothiazoline- 6-sulfonic acid)) assays. Validation experiments demonstrated a close alignment between predicted and experimental values, confirming the model's robustness. These findings indicate that ethyl lactate effectively extracts not only carotenoids but also a wide range of antioxidants, underscoring its potential as a sustainable solvent for developing functional food ingredients.

산초나무(Zanthoxylum schinifolium) 종자는 동아시아에서 향신료 및 약용 자원으로 널리 활용되고 있으나, 화학적으로 규정된 지표물질을 기반으로 한 체계적인 품질평가 기준은 아직 확립되지 않았다. 본 연구에서는 HPLC–DAD와 LC–MS/MS 분석을 통합적으로 적용하여 산초나무 종자의 품질평가를 위한 지표물질로서 hesperidin을 확인하고 검증하였다. 산초 종자의 메탄올 조추출물에 대해 크로마토그래피 분석을 수행한 결과, 주요 플라보노이드 성분들은 UV 흡수 특성과 음이온 ESI–MS/MS 단편화 패턴을 통해 동정되었다. 특히 m/z 609.6[M–H]–의 주요 전구체 이온은 hexose (162Da)와 rhamnose (146Da)의 순차적 중성손실을 거쳐 각각 m/z 463.4 및 301.3의 단편 이온을 생성하였으며, 이러한 단편화 거동은 표준물질 hesperetin-7-O-rutinoside (hesperidin)의 스펙트럼과 완전히 일치하였다. 이후 정량분석을 위해 확립된 HPLC–DAD 분석법은 우수한 직선성(R2 > 0.999), 높은 민감도(LOD 및 LOQ가 허용 범위 내), 그리고 재현성과 정밀도를 나타내어 분석법의 신뢰성을 확인하였다. 또한 여러 배치의 산초나무 종자 시료에서 hesperidin 함량이 일관되게 검출되어, 본 성분이 품질관리 지표물질로서 적합함을 확인하였다. 종합적으로, HPLC–MS/MS 기반 구조 규명과 정량 분석 결과는 hesperidin이 산초나무 종자의 주요 플라보노이드 배당체이며, 화학적 표준화 및 품질평가를 위한 적절한 지표성분임을 명확하게 보여준다. 본 연구는 산초나무 유래 기능성 소재의 산업적 활용과 표준화, 품질 보증을 위한 분석 기반을 제공하는 데 중요한 의의가 있다.

This study assessed how fruit size and cultivation region affect the distribution of carotenoids and flavonoids in sweet persimmon (Diospyros kaki Thunb.). We quantified concentrations in the whole fruit, peel, and pulp, and compared them across different size grades and cultivation regions. The fruit size did not significantly influence the levels of carotenoids or flavonoids, suggesting a limited direct relationship with phytochemical accumulation. Notably, the peel consistently contained the highest concentrations of the compounds analyzed. Regional comparisons revealed significant variability. In the whole fruit, flavonoids—except for quercetin 3-O-galactoside (Q3Gal)—were most concentrated in Gwangyang. In the peel, Q3Gal, quercetin 3-O-glucoside (Q3Glu), and zeaxanthin were most abundant in Naju–Yeongam, while β-carotene peaked in Gimhae–Changwon. To identify environmental influences, we examined climatic variables and found that a larger diurnal temperature range during the dormancy stage of fruit development correlated positively with higher flavonoid levels. Overall, these findings indicate that the functional components of sweet persimmon are primarily influenced by the growing region—potentially due to local weather conditions—rather than by fruit size. Additionally, consuming persimmons with their peel may enhance the intake of beneficial plant-derived compounds.

본 연구는 식물공장에서 미나리(Oenanthe javanica DC.) 를 초장별(20cm, 30cm, 40cm, 50cm)로 재배할 경우 기능성 물질과 영양학적 가치가 유지되는지를 평가하기 위해 수행되 었다. 미나리는 항산화 효과, 항염증, 간 보호 등 다양한 생리 활성을 갖춘 기능성 채소로, 기존 재배 방식의 한계를 극복하 고 연중 안정적인 생산이 가능한 식물공장 재배 가능성을 확 인하는 것이 본 연구의 목적이다. 연구 결과, 초장 30cm에서 칼륨(K)과 칼슘(Ca) 함량이 가장 높았으며, 비타민 C 함량 또 한 1,165.38mg·kg-1으로 가장 높았다. 총 폴리페놀 함량은 초 장 20－40cm에서 유사한 수준을 유지하였으며, 초장 50cm 에서 감소하는 경향을 보였다. 기능성 물질인 Quercetin, Apigenin, Isorhamnetin 함량은 초장에 따른 변동 폭이 크지 않아, 단기 재배된 초장이 짧은 미나리도 충분한 기능성 물질 을 함유하고 있음을 확인하였다. 식이섬유 함량 또한 모든 초 장에서 일정 수준(300g·kg-1 이상)을 유지하여 건강 기능성 채소로 활용 가능성이 높았다. 본 연구 결과를 종합하면, 식물 공장에서 초장 30cm로 재배된 미나리는 높은 영양 가치와 기 능성을 유지할 수 있으며, 기존 노지재배 방식과 비교해 연중 균일한 생산이 가능하여 산업적 활용 가치가 클 것으로 판단 된다.

This study investigated the correlation between compound malodor and total hydrocarbons (THC) to evaluate the potential use of THC as a predictor of compound malodor. A total of 87 samples were analyzed from five target facilities: two petrochemical manufacturing facilities (A, B), a wastewater treatment facility (C), a recycled plastic injection molding facility (D), and a surfactant manufacturing facility (E). The correlation coefficients of compound malodor and THC for each facility were as follows: A: 0.6698, B: 0.8068, C: –0.2767, D: 0.2071, and E: 0.7695. The correlation coefficient for all facilities was 0.5634, indicating a weak correlation. The coefficients of determination for the regression analysis to predict the compound malodor for facilities A, B, and E were 0.4093, 0.6316, and 0.5695, respectively, which validated the results of the correlation analysis. These values improved to 0.8394, 0.6941, and 0.7476 in the multiple regression analysis with the VOC analysis results added as independent variables. Therefore, it is expected that THC measurement that considers the characteristics of the facility can be used to establish a systematic odor management plan.

Electrical and thermal transport properties of a polycrystalline carrier-doped wide-gap semiconductor LaCu1-δ S0.5Se0.5O (δ = 0.01), in which the CuCh (Ch = S, Se) layer works as conducting layer, were measured at temperatures 473~673 K. The presence of δ = 0.01 copper defects dramatically reduces the electrical resistivity (ρ) to approximately one part per million compared to that of δ = 0 at room temperature. The polycrystalline δ = 0.01 sample exhibited ρ of 1.3 × 10-3 Ωm, thermal conductivity of 6.0 Wm-1 K-1, and Seebeck coefficient (S) of 87 μVK-1 at 673 K. The maximum value of the dimensionless figure of merit (ZT) of the δ = 0.01 sample was calculated to be 6.4 × 10-4 at T = 673 K. The ZT value is far smaller than a ZT ~ 0.01 measured for a nominal LaCuSeO sample. The smaller ZT is mainly due to the small S measured for LaCu1-δS0.5Se0.5O (δ = 0.01). According to the Debye model, above 300 K phonon thermal conductivity in a pure lattice is inversely proportional to T, while thermal conductivity of the δ = 0.01 sample increases with increasing T.

다알리아(Dahlia pinnata Cav.)는 멕시코 아즈텍인들이 식용으로 재배하여 꽃잎은 샐러드로, 뿌 리는 식용이나 약재로 사용하였다. 그러나 현재는 대부분 화훼용으로 사용되고 있으며, 식용이나 약재로서 의 연구는 부족한 실정이다. 본 연구에서는 다알리아 꽃을 차로 제조하여 다양한 침출 조건과 제다법을 사 용하여 항산화 활성 및 생리활성 성분 함량을 평가하였다. 항산화 활성은 DPPH radial 소거 활성으로 평 가하였으며, 생리활성 성분은 총 폴리페놀 함량(TPC)과 총 플라보노이드 함량(TFC)을 분석하였다. 건조된 다알리아 꽃차는 90℃에서 침출하였을 때 가장 높은 생리활성물질을 추출할 수 있었으며, 적절한 침출 시 간은 8분, 침출 횟수는 3회가 적합하였다. 다양한 제다 방법 중에서 증제법이 가장 높은 항산화 활성을 보 였으며, 그 다음으로 생화, 건조, 덖기 순으로 나타났다. 증제된 다알리아 꽃차의 총 폴리페놀 함량과 플라 보노이드 함량은 각각 50.9 mg/g과 80.6 mg/g으로 건조된 녹차와 비교했을 때 폴리페놀 함량은 낮지만 플라보노이드 함량은 약 3배 높게 나타났다. 이러한 결과는 다알리아 꽃이 우수한 생리활성물질을 함유하 고 있으며, 항산화제로서 식품 및 의약품, 화장품 등에서 높은 활용 가능성을 가지고 있음을 시사한다.

본 연구는 과피색에 따른 토마토 과실의 숙성 단계에 따른 기능성 물질 및 항산화 활성의 차이를 알아보기 위해 실시하 였다. 토마토 샘플은 성숙한 단계에서 과피색이 황색, 흑색, 적 색으로 구별되는 세 가지 토마토 품종을 이용하였다. 토마토 샘플을 녹색기, 변색기, 최색기, 완숙기의 4가지 숙성 단계에 서 수확한 후 당, 라이코펜, 아스코르브산, 폴리페놀 및 항산화 활성을 포함한 다양한 생리 활성 화합물을 분석하였다. 토마 토 과실의 주요 당분은 과당과 포도당이다. 황색 토마토의 과 당과 포도당 함량은 숙성 단계에 따라 점차 증가하였다. 그러 나 흑색 토마토와 적색 토마토는 변색기 단계에서 증가한 후 상대적으로 일정하게 유지되었다. 과피색에 관계없이 모든 토마토 과실에 함유된 라이코펜 함량은 숙성 단계에 따라 크 게 증가했습니다. 라이코펜 함량은 적색 토마토 과실의 성숙 단계에서 가장 높게 관찰되었다. 황색 토마토 과실의 아스코 르브산 함량은 낮았으며 숙성 단계 동안 상대적으로 일정하게 유지되었다. 흑색 토마토 과실의 아스코르브산 함량은 성숙 단계에서 2,249mg·kg-1으로 크게 증가한 반면, 적색 토마토 과실에서는 성숙 단계에서 3,529mg·kg-1으로 점차 증가했습 니다. 페놀성 화합물인 퀘르시트린은 토마토 과실에서 발견 되었지만, 성숙 단계에서 토마토 과실의 퀘르시트린 함량은 점차적으로 감소되었다. ABTS 라디칼 소거 활성은 최색기의 황색 토마토 과실에서 급격히 증가한 반면, 흑색 토마토와 적 색 토마토에서는 숙성 단계에 따라 점진적으로 증가하였다. 모든 토마토 과실의 DPPH 라디칼 소거 활성은 최색기에서 크 게 증가했다.

Compound characters in oracle bone inscriptions refer to the form of two or three oracle bone characters combined together. These characters, formed after combination, are called compound characters and represent one of the structural features of oracle bone scripts. The phenomenon of compound characters is prevalent among river names in oracle bone inscriptions. Based on this observation, we propose that the formation of river names in oracle bone inscriptions was initially the combinations of geographic names and rivers, and these compound character forms have generally gone through a development process from separate characters to compound characters. Through the study of the structure formation of river names in oracle bone inscriptions, a deeper understanding of the people’s perceptions of river systems and geographical environments during the Shang Dynasty can be obtained, as well as the relationship between geographic names and rivers.

The aim of this study was to improve the chemical stability of cycloserine containing organic and inorganic compounds. Composite particles were manufactured with a 1:1 weight ratio of organic/inorganic compounds and cycloserine. The influence of organic/inorganic compounds on the stability of cycloserine was investigated under accelerated stress conditions at 60°C/75% RH for 24 hours. In addition, the properties of the composite particles were evaluated using differential scanning calorimetry (DSC), scanning electron microscopy (SEM), and the dissolution of the drug was assessed by preparing it as a hard capsule. Among the organic and inorganic compounds investigated, calcium hydroxide most improved the stability of cycloserine under accelerated stress conditions (53.3 ± 2.2% vs 1.7 ± 0.2%). DSC results confirmed the compatibility between calcium hydroxide and the cycloserine, and SEM results confirmed that it was evenly distributed around the cycloserine. Calcium hydroxide also showed more than 90% cycloserine dissolution within 15 minutes. Therefore, the calcium hydroxide and cycloserine composite particles may be candidates for cycloserine oral pharmaceuticals with enhanced drug stability.

Hypertension is characterized by excessive renin-angiotensin system activity, leading to blood vessel constriction. Several synthetic compounds have been developed to inhibit renin and angiotensin-converting enzyme (ACE). These drugs often have adverse side effects, driving the exploration of plant protein-derived peptides as alternative or supplementary treatments. This study assessed the phenolic compound and amino acid content and the antioxidant and antihypertensive activity of 5 South Korean staple crops. Sorghum had the highest phenolic compound content and exhibited the highest antioxidant activity. Millet grains, particularly finger millet (38.86%), showed higher antihypertensive activity than red beans (14.42%) and sorghum (17.16%). Finger millet was found to contain a large proportion of branched-chain, aromatic, and sulfur-containing amino acids, which are associated with ACE inhibition. In particular, cysteine content was positively correlated with ACE inhibition in the crops tested (r=0.696, p<0.01). This study confirmed that the amino acid composition was more correlated with the antihypertensive activity of grains than the phenolic compound content. Finger millet mainly contained amino acids, which have higher ACE inhibitory activity, resulting in the strongest antihypertensive activity. These findings underscore the antihypertensive potential of select crops as plant-based food ingredients, offering insight into their biological functions.

To produce an intestinal immunomodulatory beverage containing Centella asiatica extract (CAE), three types of CAE-added beverage prototypes were prepared, and their immunomodulatory activities and marker compounds were analyzed. As a result of the cytotoxicity assessment, all the beverages did not show significant toxicity compared to the control group. Next, the immunomodulatory activities of the beverage prototype were evaluated using the inflammatory model of IL-1β-induced intestinal epithelial cell line. All the samples significantly reduced the production of IL-6, IL-8, and MCP-1 in a CAE concentration-dependent manner. In addition, CAE-added beverages inhibited NO, IL-6, and IL-12 production in LPS-induced RAW 264.7 cells. When the major triterpenoids, as marker compounds for the production of CAE-added beverages, were analyzed by HPLC-DAD, only asiaticoside was detected beyond the limit of quantification, while madecassoside, madecassic acid, and asiatic acid were not detected. The amounts of asiaticoside in CAE-added beverage prototypes were confirmed in No. 1 (19.39 μg/mL), 2 (19.25 μg/mL), and 3 (19.98 μg/mL). In conclusion, the results of this study suggested that CAE-added beverage prototypes induced immunomodulatory effects in the intestinal inflammatory cell line models and asiaticoside could be used as a marker compound for CAE-added beverage production.

We determined physicochemical characteristics and antioxidant activities of cookies prepared by replacing wheat flour with 0, 3, 6, and 9% freeze-dried burdock powder instead of wheat flour. The leavening and loss rates of the cookies decreased in proportion to the amount of burdock powder added to the dough. The moisture content of the cookies increased in proportion to the amount of burdock powder added and the crude protein and hardness were higher in the burdock-added group compared to the control. The lightness and yellowness of the cookies decreased, and the redness increased in proportion to the amount of burdock powder added. The total flavonoid and polyphenol compounds in the cookies increased in proportion to the amounts of burdock powder added. The antioxidant activities also tended to increase in proportion to the amount of burdock powder added. Based on the above results, adding burdock powder to cookies can increase antioxidant activity by increasing the content of antioxidant components, such as polyphenols and flavonoids. In addition, it is believed that adding burdock powder at levels of 3 to 9% of the weight of flour would result in cookies with spreadability, swelling power, and hardness similar to those of regular cookies.