목적 : 본 연구의 목적은 발달장애 아동의 사회성 발달수준을 평가하기 위한 태블릿 기반의 사회성평가를 개발하고 개발된 각 항목의 예비타당도를 연구하고자 함이다. 연구 방법 : 문헌 고찰을 통해 발달장애 아동과 관련이 있는 사회성 요소들을 선별하고 평가의 구성 개념을 정립하였다. 내용 타당도를 정립하기 위하여 전문가 패널을 구성하여 델파이 조사를 시행하였다. 이후 사회성평가 애플리케이션의 디자인 설계, 개발, 및 사용성 평가 등의 과정을 거쳐 평가를 개발하였다. 개발된 평가의 타당도를 검증하기 위하여 공인 타당도와 판별 타당도를 알아보았다. 공인 타당도 검증을 위해 한국어판 사회적 의사소통 설문지(Korean version of Social Communication Questionnaire; K-SCQ) 및 사회성숙도 검사(Social Maturity Scale; SMS)와 개발된 사회성평가 점수 간의 상관관계 를 분석하였다. 판별 타당도를 알아보기 위하여 정상발달 아동 32명과 발달장애 아동 16명과의 사회성 평가 결과를 평균 비교 분석을 시행하였다. 결과 : 연구 결과 총 3개의 대분류 안에 8개의 세부 평가항목으로 구성되었다. 세부 평가항목으로는 지시따르기, 모방, 주의공유, 전상징기적 지식, 상징행동, 규칙이해, 감정지각, 조망수용이 있다. 각 항목에 대한 구성 및 과제 적절성을 델파이 조사결과 모든 항목이 CVR .8-1로 나타났다. 사회성평가의 모든 항목에서 정상발달아동과 발달장애아동의 수행결과가 통계적으로 유의미한 것으로 나타났다(-5.1, p = .000). 아울러 K-SCQ 및 SMS 점수와 개발한 사회성 평가 점수간의 상관관계가 있는 것으로 나타났다(-.69, .57, p < .01). 결론 : 본 연구에서는 태블릿 기반의 사회성 평가항목을 개발하였고, 각 평가항목과 구성이 타당한 것으로 나타났다. 본 연구에서 개발된 사회성평가를 통해 발달장애 아동의 사회성 발달수준을 평가할 수 있고, 향후 임상과 교육현장에서 널리 활용되기를 기대한다.

The purpose of this study is to optimize the powder formulation and manufacturing conditions for the solidification of an extract of the herb Bangpungtongseong-san (BPTS). To develop BPTS-loaded particles for the tablet dosage form, various BPTS-loaded particles composed of BPTS, dextrin, microcrystalline cellulose (MCC), silicon dioxide, ethanol, and water are prepared using spray-drying and high shear granulation (high-speed mixing). Their physical properties are evaluated using scanning electron microscopy and measurements of the angle of repose, Hausner ratio, Carr’s index, hardness, and disintegration time. The optimal BPTS-loaded particles exhibit improved flowability and compressibility. In particular, the BPTS-loaded particles containing silicon dioxide show significantly improved flowability and compressibility (the angle of repose, Hausner ratio, and Carr’s index are 35.27 ± 0.58°, 1.18 ± 0.06, and 15.67 ± 1.68%, respectively), hardness (18.97 ± 1.00 KP), and disintegration time (17.60 ± 1.50 min) compared to those without silicon dioxide. Therefore, this study suggests that particles prepared by high-speed mixing can be used to greatly improve the flowability and compressibility of BPTS using MCC and silicon dioxide.

수경재배시 양액 내 탄산정 처리를 통한 상추의 생육 및 생리활성물질 변화를 조사하기 위해 네덜란드에서 시판되는 고형 탄산정을 사용하였다. 실험은 무처리를 대조구로 하여 0.5 배, 1배, 2배 처리구로 구성하였다. 실험결과, 탄산정 처리 후 챔버내 대기 CO2 농도는 처리 직후 2배 처리구에서 472.2μL·L -1 로 가장 높은 수치를 보였으며, 양액내 pH는 2배 처리구는 pH 6.03로 가장 많이 감소하였다. 이후 시간이 경과함에 따라 CO2 농도와 pH는 처리 전 수준으로 회복하는 모습을 나타냈다. 상추의 엽폭과 엽면적은 탄산정 2배 처리시 17.1cm, 1067cm 2로 가장 큰 값을 나타내었으며 지상부 생체중, 건물 중은 0.5배 처리구에서 63.87g, 3.08g으로 가장 높게 나타났다. 상추의 근장은 대조구에서 28.4cm로 가장 길었으나 처리 구들간에 지하부의 생체중, 건물중은 유의적인 차이를 나타내지 않았다. 외관상 탄산정 처리에 의해 상추의 근장이 짧아 지고 곁뿌리가 많이 발생한 것이 관찰되었다. 또한 뿌리가 갈색으로 약간 변하는 결과가 있었지만, 지상부 생육에는 부정적인 영향을 미치지 않은 것으로 나타났다. 탄산정 처리에 의 한상추의 생리활성물질을 분석한 결과 chlorogenic acid와 quercetin 두가지 물질이 검출되었으며 이를 정량분석한 결과 1배 처리구에서 chlrogenic acid는 대조구보다 249% 증가하였지만 quercetin은 37% 감소한 결과를 나타냈다. 항산화 활 성을 나타내는 DPPH 라디컬 소거능을 비교한 결과 대조구와 0.5배 처리가 1배, 2배 처리보다 유의적으로 높은 값을 나타냈다. 이를 통해 탄산정 처리가 수경재배 상추의 생육과 생리활 성물질을 증대에 효과가 있음을 제시한다.

목적 : 본 연구에서는 뇌졸중 환자를 대상으로 Tablet PC 기반 인지 평가도구와 MMSE-K, MoCA-K를 비교하여 공인타당도와 Tablet PC 기반 인지 평가도구의 검사-재검사를 시행하여 신뢰도를 알아보고자하였다. 연구방법 : 본 연구는 2018년 6월 18일부터 2018년 9월 16일까지 시행하였으며, 울산에 소재한 종합병 원에 입원하여 작업치료를 받는 67명의 아급성 뇌졸중 환자를 대상으로 하였다. 평가는 MMSE-K, MoCA-K, Tablet PC 기반 인지 평가도구를 사용하였다. 공인타당도와 검사-재검사 신뢰도는 Pearson 상관분석을 사용하였다. 결과 : 공인타당도를 분석한 결과 Tablet PC 기반 인지 평가도구와 MMSE-K의 상관계수는 r=.85(p<0.01), MoCA-K의 상관계수는 r=.86(p<0.01)로 높은 공인타당도를 보였다. 신뢰도는 r=.97(p<0.01)로 검증 되었다. 결론 : 본 연구를 통해 Tablet PC 기반 인지 평가도구의 공인타당도와 신뢰도를 검증하였으며, Tablet PC 기반 인지 평가도구가 임상에서 인지 평가도구로서 사용될 수 있는 근거를 제시하였다.

The history of the spread and development of Chinese characters in Korea is very long. Chinese characters were introduced into the Korean peninsula as early as in the period from the end of the Han Dynasty to the Three Kingdoms (A.D. 3C). Until the end of the 19th century, Chinese characters were the official writing system in Korea. The Korean peninsula has a history of using Chinese characters for over 1,500 years. It has an incomparably rich collection of ancient texts and documents written with Chinese characters. Of them are a considerable number of stone carvings that authentically recorded the profound literacy of the Korean people in the Middle Ages as far as the culture of Chinese characters is concerned. At the same time, these stone carvings are also of valuable reference for the developmental transformations and the configurational patterns since the formation of the clerical script, through the Wei-Jin period, the Sui and the Tan dynasties, and all the way through modern times. The present study takes as an example of the stone tablet of Master Chinkam Sŏnsa of the Silla era collected in Korean Grand Compendium of Ancient Inscriptions published by the Korean Studies Institute. I specifically summarized and analyzed the alternative script of ancient Chinese characters in the Korean stone carvings. I found out that there are characters written with different strokes or in a different internal structure, those which have been simplified, those which some parts have been added to or subtracted from, and those with a different position. Then I explored the formation and the developmental trajectory of individual variant forms of a Chinese character. Thus, I grasped the reasons for the formation of the variant Chinese characters in Korean ancient stone carvings as well as their writing characteristics.

To develop Taraxacum platycarpum extract (TP)-loaded particles for tablet dosage form, various TP-loaded particles composed of TP, dextrin, microcrystalline cellulose (MCC), silicon dioxide, ethanol, and water are prepared using a spray-drying method and fluid-bed-drying method. Their physical properties are evaluated using angle of repose, Hausner ratio, Carr’s index, hardness, disintegrant time, and scanning electron microscopy. Optimal TP-loaded particles improve flowability and compressibility. Furthermore, 2% silicon dioxide gives increased flowability and compressibility. The formula of TP-loaded fluid-bed-drying particles at a TP/MCC/silicon-dioxide amount of 5/5/0.2 improves the angle of repose, Hausner ratio, Carr’s index, hardness, and disintegrant time as compared with the TP-loaded spray-drying particles. The TP-loaded fluid-bed-drying particles considerably improve flowability and compressibility (35.10° vs. 40.3°, 0.97 vs. 1.17, and 18.97% vs. 28.97% for the angle of repose, Hausner ratio, and Carr’s index, respectively), hardness (11.34 vs. 4.7 KP), and disintegrant time (7.4 vs. 10.4 min) as compared with the TP-loaded spray-drying particles. Thus, the results suggest that these fluid-bed-drying particles with MCC and silicon dioxide can be used as powerful particles to improve the flowability and compressibility of the TP.

목적 : 본 연구에서는 체계적 고찰을 통해 지적장애 아동을 대상으로 한 태블릿PC의 활용 유형 및 중재효 과를 분석하여 지적장애 아동을 대상으로 한 치료 중재에 있어서 보다 효율적인 태블릿PC 및 소프트웨 어의 활용을 위한 근거를 마련하고자 한다. 연구방법 : 2010년부터 2015년 12월까지 국외 학술지 검색 시스템을 사용하였고 주요 검색용어로는 ‘tablet PC’와 ‘intellectual disabilities’로 하였다. 추가 검색어로는 ‘iPad’, ‘iPod’, ‘portable multimedia device’, ‘tablet computer’를 사용하여 총 9개의 논문을 선정하였다. 결과 : 태블릿PC 활용유형에 대한 분석을 한 결과 모바일 어플리케이션을 활용한 연구(55.5%), 직접 제작 한 멀티미디어 자료(22.2%), 비디오 모델링(11.1%), 디지털 교과서(11.1%)순으로 나타났다. 태블릿PC 의 중재 결과로는 학업수행 향상(33.3%), 과제수행 변화(22.2%), 수업참여(11.1%), 의사소통(11.1%), 사회성(11.1%)에 관련한 연구 순으로 나타났다. 결론 : 본 연구는 지적아동을 대상으로 한 태블릿PC 활용유형 및 중재결과를 제시함으로서 태블릿PC를 중 재에 활용 하고자 할 때 도움이 될 수 있는 정보를 제공하였고, 향후 치료 목표 및 중재에 대한 근거를 제시 하는데 도움이 될 것이다.

Existing studies of Japanese consumers have emphasized the importance of collectivism and risk aversion in Japanese culture. In this paper we examine the relationship between these constructs in new product adoption decisions that involve brand switching. We argue that, for Japanese consumers, the perceived emotional risk of adoption is related to (1) the degree to which a consumer identifies with the brand of his or her current product and (2) the perceived performance, financial, and social risks of switching to an alternative product. We further hypothesize that perceived social risk is positively related to brand identification, perceived performance risk, and perceived financial risk. Finally, we hypothesize that financial risk is positively related to performance risk. We test our hypotheses using data collected in Japan in June 2015. Questionnaire items were adapted from existing, well-validated scales. The Japanese version of the questionnaire was developed by using the standard double translation procedure. The Japanese version of the questionnaire was administered by a marketing research firm to a national panel of respondents stratified by age and gender. The resulting sample consisted of 518 iPad owners from across Japan, of whom approximately half were men. Within each gender category, approximately half of the respondents intended to purchase a new tablet within the next 12 months. Following established SEM procedures, we began by estimating a confirmatory factory analysis model, after which we estimated a structural equation model. In each case, the estimated model satisfied standard evaluation criteria. In general, our findings provide support for the hypothesized model. First, Perceived Performance Risk was positively related with Financial Risk, Social Risk, and Emotional Risk. Second, Financial Risk was positively related with Social Risk. Third, Social Risk was positively related with Emotional Risk. Fourth, Brand Identification was positively related with Social Risk and Emotional Risk. The one hypothesized linkage that was not supported was the relationship between Financial Risk and Emotional Risk. A comparison of coefficient magnitudes reveals several important findings. First, in the Social Risk equation, the coefficient of Performance Risk is significantly larger than the Brand Identification coefficient. Second, within the Emotional Risk equation, the coefficient of Performance Risk is significantly larger than the coefficients of Brand Identification and Financial Risk. Similarly, the coefficient of Social Risk is also significantly larger than the coefficients of Financial Risk and Social Risk.

Human mouth environment is known to include a variety bacteria, including Streptococcus spp., Staphylococcus spp., Actinomyces spp., Lactobacillus spp., Candida spp., Enterobacteriaceae, et al. Human oral microorganisms can cause dental caries, gingivitis, periodontitis, respiratory tract infection, and cardiovascular disease. Thus, right denture cleaning is essential to oral and general human health. The aim of this study was to evaluate the bactericidal effect of a sodium dichloroisocyanurate-based effervescent tablet (Aos Denti Germ, Aos Company, Chungbuk, Korea) against oral microorganisms. A total of 5 species Streptococcus spp. (Streptococcus anginosus, Streptococcus mitis, Streptococcus mutans, Streptococcus oralis, and Streptococcus sobrinus), Actinomyces oris, Candida albicans, and Escherichia coli were used in this study. All strains were exposed to the distilled water prepared with effervescent tablet. After the exposure, the mixture of strains and effervescent tablet was inoculated onto blood agar or MacConkey agar plate and cultured at 36℃. All strains were killed immediately on exposure to effervescent tablet. The results suggested that effervescent tablet could be used as an effective denture cleanser for dental hygiene.

This study is to introduce the development of the single tablet press used to test tablets for the purpose of their pharmaceutical development and production. This product which has been dependent entirely on imports is localized by finding the improvement of existing products and by reflecting it in the product development. Its performance evaluation has met the satisfactory target in the area of weight, hardness and productivity. It is expected that its mass production can be allowed by recognizing the effect of single tablet press which has been used in the domestic bio-pharmaceutical industry and by securing its basic production techniques.

The present study sought to investigate whether Korean learners would benefit from tablet PC-based English learning and how they and their instructors would perceive the relatively new mobile technology as a language learning and teaching tool. To this end, 161 young learners and 57 instructors at private English institutes in several cities in Korea took part in the present study. For three months, the learners received one of two forms of instruction, one based on traditional paper-based materials and the other via tablet PC-based materials. Analyses of the listening and reading tests and of the questionnaire responses, followed by student interviews, indicate that the learners may benefit from tablet PC-based English programs, especially in their reading skills and their learning autonomy. Furthermore, the learners’ beliefs in the effectiveness of tablet PC-based instruction were found to be stronger than among the instructors. Pedagogical implications and future research directions are discussed.

본 연구에서는 VDT(Visual Display Terminals) 환경에서 배경색과 가독성의 상관관계를 알아보았다. 본 실험에 앞서 예비실험으로 색 온도가 다른 White 지각도를 알아보았으며, 실험 자극물은 태블릿 PC를 활용하였다. 실험 환경은 주광과 야외광이 함께 공존할 수 있는 창가에서 실험 자극물을 제시하였다. White 지각도의 인식과 선호 결과 중·단파장계열의 Nearly Whites 색에서 백색에 대한 높은 선호도와 인식도를 보였다. 이러한 예비실험 결과를 바탕으로 본 연구에서는 동일한 실험 환경과 실험 기기를 가지고 빨간색, 초록색, 파란색, 노란색의 총 4가지 Nearly Whites와 한 가지 백색을 배경색으로 사용하여 배색 평가, 가독성, 피로도를 조사하였다. 또한, 글자는 검은색으로 제한하였다. 그 결과, 초록색의 Nearly White 배경색에서 가독성과 배색 평가가 높게 나타났으며, 가독시 느끼는 피로도는 가장 낮은 것으로 나타났다. 이와 반대로 빨간색의 Nearly White 배경색에서는 가독성과 배색 평가가 가장 낮게 나타났으며, 가독 시 느끼는 피로도는 가장 높은 것으로 나타났다. 이러한 연구 결과를 통해서 VDT 환경에서의 가독성을 향상시키며, 눈의 피로도를 낮출 수 있는 배경색을 제안해 보고자한다.

Vibrio spp. and Streptococcus spp. have caused a considerable disease of farmed fish and economic loss in fish farming and seafood industry. In this study, the efficacy of an aquatic disinfectant tablet composed to calcium hypochlorite was evaluated against V. anguillarum and S. iniae. A bactericidal efficacy test by broth dilution method was used to determine the lowest effective dilution of the disinfectant following exposure to test bacteria for 30 min at 4oC. An aquatic disinfectant tablet and test bacteria were diluted with distilled water (DW), hard water (HW) or organic matter suspension (OM) according to treatment condition. V. anguillarum on the DW, HW and OM condition was completely inactivated with 16,000 15,000 and 13,000 fold dilutions of the disinfectant, respectively. On the DW, HW and OM condition, S. iniae was absolutely inactivated with 17,000 16,000 and 14,000 fold dilutions of the disinfectant, respectively. As an aquatic disinfectant tablet possesses bactericidal efficacy against fish pathogenic bacteria such as V. anguillarum and S. iniae this disinfectant solution can be used to control the spread of fish infective bacterial diseases.

In this study, the veridical efficacy of an aquatic disinfectant tablet composed to calcium hypochlorite against red sea bream iridovirus (RBIV). A veridical efficacy was determined with the viability of RBIV contacted with the disinfectant in viral stock cultured in fat head minnow cell line. An aquatic disinfectant tablet and RBIV were reacted on the distilled water (DW), hard water (HW) or organic matter suspension (OM) condition. On DW and HW condition, RBIV was inactivated with 25,000 fold dilutions of an aquatic disinfectant tablet. With the investigation of the antiviral effect of the disinfectant on OM condition, RBIV was inactivated on 22,000 fold dilutions of an aquatic disinfectant tablet. As an aquatic disinfectant tablet possesses veridical efficacy against RBIV, the disinfectant solution can be used to limit the spread of cultured marine fish viral disease.

In this study, we have prepared three kinds of enteric tablet coating formulations for prevention the crack incidence and enhanced process improvement of enteric tablet using aqueous system. we determined the mechanical strength of three formulatons on the enteric film-coating process. The compared experiment of one-layer and two-layer (A), (B) coating treated having placebo tablets without breakline and logo. In result, the breaking force time of two-layer (B) film strength was found to increase 0.8min than two-layer (A). We confirmed the half reduction of working hour and the simplification in the one-layer coating process, and the coating troubles was solved as setting up a dehumidifier in inlet of coater. In result, we recovered that optimum running capacity(g/kg) of dehumidifier is 10g/kg and below.