A Blast valve is the device that is used in the air intake and the exhaust vent of CBRN(Chemical, Biological, Radiological and Nuclear warfare) protection facility. The valve is automatically closed when explosion pressure is applied from the outside of equipment. This study is investigated on the structural design and the performance of blast valve. After modeling the entire of blast valve and spring assembly, the data for the spring parameter is obtained through the finite element method and the operating limits of the valve are derived. Also, a prototype is made to determine the relationship between the load and the opening closing amount of valve through the load cell test. The performance of prototype at analysis as blast valve is agreed well with that at experiment. It is verified that the blast valve proposed in this paper is designed with the structure to endure the explosion pressure.

고창군 광승리 지역의 해발고도 5 m 내외의 해안 지점(DH)과 해발고도 10-15 m의 단구 상부 지점(KS)에서 시료를 채취하여 화학 분석과 입도 분석 등을 통하여 퇴적 물질의 특성을 파악하였다. DH는 풍화된 기반암을 피복하는 적색 토양층으로 하부에서 상부로 가면서 물질 조성이 점진적으로 변화하였다. DH 시료 내에 점토광물이 포함되어 있는 것으로 나타났다. 이를 근거로 하여 이 층을 제자리 풍화층으로 판단하였다. KS의 경우 구릉의 말단부에 위치하는 자갈층을 피복하는 층으로 물질 조성이 전반적으로 DH 부분과 상당히 다른 것으로 나타났으며, 일부 구간에서 물질의 교란이 일어나거나 외부 물질의 유입이 있었던 것으로 추정되었다. 한편 입자의 입도에 있어서 KS 시료들은 현재의 해빈 물질과 다른 특성이 나타난다. KS의 하부는 해빈에 비하여 세립 물질로 나타났으며, 중간 부분은 해빈보다 조립 물질이다. KS 시료의 분급은 해빈에 비하여 나쁜 것으로 나타났으며, 이 퇴적층중 일부는 지속적인 파랑과 조류에 의한 것보다는 일시적인 고에너지 환경에서 퇴적된 것으로 추정된다. 한편 KS 부분 시료의 매몰 연대는 광여기루미네센스(OSL) 분석에 의하여 0.65-0.71 ka로 추정되었다. 추가적인 연구를 통해 해당 퇴적층과 형성 과정의 특성에 대해서는 명확히 밝혀져야 할 것이지만, 해당 퇴적층은 폭풍에 의한 연안 범람 퇴적층일 가능성이 높은 것으로 추정된다.

본 연구는 조직 내 교환관계에서 부하에게 제공되는 다수의 보상원천에 대해 상사와 부하가 이것을 다양한 원천이라고 지각하는가 아니면 동일한 원천이라고 지각하는가에 대한 질문에 답하기 위하여 수행되었다.이러한 물음에 답하기 위하여 먼저 상사로부터 많은 보상을 제공받는다고(상사로부터의 유인) 지각하는 부하들은 그들의 상사를 만족시킬 수 있는 성과를 보일 것(부하의 기여)이라는 가설 1을 설정하였다.둘째,직무로부터 많은 보상을 제공받는다고(직무로부터의 유인)지각하는 부하들은 직무를 수행하는데 더 많은 시간과 에너지를 기울일 것(직무에 대한 기여)이라는 가설 2를 설정하였다.이러한 두 가지 가설은 조직 내 교환관계에서 상사와 직무로부터의 보상에 대해 상사와 부하가 다양한 보상원천이라고 지각하는 것을 의미한다.이러한 견해와는 반대로 상사와 부하가 다양한 보상원천을 동일하다고 지각하는 경우 상사로부터의 보상과 상사를 만족시킬만한 성과의 제공 그리고 직무로부터의 보상과 직무에 대한 시간과 노력의 투입이 하나의 네트워크를 이룬다는 가설 3을 설정하였다.이와 더불어 상사는 상사-부하 간 유인과 기여와 직무로부터의 유인과 기여를 구별하지 않는 반면, 부하는 상사-부하 간 유인과 기여, 직무로부터의 유인과 기여를 구별할 것이란 가설 4를 설정하였다. 10명의 상사와 76명의 부하를 대상으로 세 차례에 걸친 상사와 부하의 응답 각각을 분석한 결과 부하들은 상사-부하 간 유인과 기여와 직무로부터의 유인과 기여를 각각 구별하는 것으로 나타난 반면 상사는 상사-부하 간 유인과 기여와 직무로부터의 유인과 기여를 구별하지 않는 것으로 나타났다. 이러한 결과는 본 연구에서 제시한 가설 4가 뒷받침되었다는 것을 보여준다. 결론부분에서는 본 연구결과가 가지는 의미를 상사의 관점, 부하의 관점, 그리고 상사와 부하의 관점으로 구분하여 논의가 이루어졌다. 특히 상사의 관점에서 상사들이 유인과 기여의 두 가지 모형을 구분하지 않는 이유를 후광효과(halo effect) 측면에서 논의하였으며 본 연구가 가지는 한계점과 추후 연구방향에 대한 논의 역시 이루어졌다.

Primary oral squamous cell carcinoma (OSCC) associated with dental osseointegrated implants is very rare. We experienced two patients who had received dental implant surgery before they were diagnosed with OSCC. We report these cases to emphasize the importance of differential diagnosis of malignant lesions associated with dental implants. Additionally, we also suggest that bone graft materials around implants can serve as a potential inducer of invasiveness in cancer cells.

Development of squamous cell carcinoma around dental implants is an uncommon clinical manifestation with only a few cases described in the literature. Recently, we observed primary squamous cell carcinoma that developed from leukoplakia around dental implants. We report this case to emphasize the importance of careful oral examination, for implant surgery has to be preceded by thorough evaluation of oral mucosal conditions.

Small cell osteosarcoma of bone, which was first described in 1979, is an unusual variant of osteosarcoma. Osteoid production by tumor cells is frequently focal or minimal, making the differential diagnosis with other small round cell tumors of bone difficult. Here, we present a rare case of small cell osteosarcoma of the mandible appearing as bony bulging mass in 31-year-old male who has neither tenderness nor paresthesia. Histologically, the tumor contains hypercellular cartilage and abnormal osteoid associated with small round to ovoid malignant cells. Awareness of small cell osteosarcoma should be emphasized because it has worse prognosis than both other small round cell tumor and conventional osteosarcoma.

Nodular fasciitis is defined by the World Health Organization as a benign proliferative fibroblastic lesion. It was first described in 1955 by Konwaler et al. and also known as “nodular pseudosarcomatous fasciitis” and “infiltrative fasciitis”, which reflect the lesion’s rapid growth, dense cellularity, alarming mitotoic activity and lack of circumscription. Here, we report a case of nodular fasciitis, which appeared as subcutaneous mass of right perizygoma area in 40-year-old Korean female. She had no history of trauma or cosmetic surgery related with the lesion. She disclosed that the mass grew rapidly for last 2 months. Computed tomography showed relatively well-defined spherical mass with 1.2 cm in diameter. Under local anesthesia the mass was resected by intraoral approach. The histological examination revealed a relatively poor-dermacated mass with high cellularity, which was composed with infiltrative spindle-shaped cells without accompanying inflammatory reactions. The tumor cells were partially positive for α-smooth muscle actin and β-catenin, but negative for cytokeratin AE1/3, S-100, desmin, and CD34. Therefore, the lesion was pathologically diagnosed as nodular fasciitis. Although nodular fasciitis is known to pseudosarcomatous benign reactive lesion, the clinician need to follow up the patient periodically. The reasons are as follows; Nodular fasciitis may accompany nuclear accumulation of β-catenin, which imply neoplastic process rather than reactive process of the lesion. Moreover, it has many histological similarities with inflammatory myofibroblastic tumor which have malignant transformation tendency. Further research for mesenchymal tumor could help our understanding for the disease entity of nodular fasciitis

The osteoblastic activity of carcinoma is restricted in osteoblastic metastasis, common in the patients with prostate cancer, whereas its mechanism and the factors involved are unknown. Here, we present a case of central adenocarcinoma showing the osteoblastic activity in the mandible of the 80-year-old Korean male who had suffered from the paresthesia of lower lip during four mouths. Clinically the overlying oral epithelium was intact, but the radiologic images revealed the ill-defined radiolucent intraosseous lesions in left ascending ramus. Microscopically, the mandibular lesion was composed with carcinoma of ductal or glandular differentiation but lack typical features of any epithelial salivary gland malignancies. Intriguingly abundant new bone formation was found in the stroma, but the tumor cells expressed no reactivity for prostate-specific antigen(PSA). The patient had low ionized calcium level, normal serum alkaline phosphatase and PSA level. Positron emission tomography-computed tomopraphy scan revealed the benign prostatic hyperplasia, but failed to trace the primary site of tumor other than mandible. Therefore, pathologically diagnosis for the lesion was informed as adenocarcinoma, not otherwise specified(NOS). Because occult primary tumor associated with osteoblastic metastasis cannot be completely ruled out, periodic and careful check-ups for the patient should be performed.

본 연구는 117개의 문화기술개발 수혜기업을 표본으로 문화기술(CT)개발지원 정책과 기업 R&D성과와의 관계를 실증분석하였다. 연구결과, 문화기술개발정책은 기업 R&D성과제고에 매우 중요한 역할을 하는 것으로 분석되었다. 특히 문화기술개발정책이 사업타당성 및 적절한 사업운영체계를 갖는 것은 전 주기적인 기업R&D성과향상에 유의적인양의 영향을 미쳤다. 곧, 타당한 문화기술개발정책은 기업이 단순히 R&D단계에 머물지 않고 기술적 성과를 발생시키며 나아가 경제적성과(사업화 성과)를 향상시킬 수 있도록 돕는 촉매역할을 하는 것으로 나타났다. 따라서, 문화기술개발정책이 시행되기 앞서 시장수요에 기반한 사업타당성확보가 선행되어야 하고 R&D지원후에도 기업과 지속적인 커뮤니케이션을 통해 정책 개선노력을 기울여야 할 것으로 보인다.

Canine parvovirus (CPV) type 2a (CPV-2a) has recently been identified as the main genotype circulating in the dog population in South Korea. Although CPV vaccines protect domestic dogs from CPV-2 infection, the efficacy of commercial live or inactivated CPV vaccines against CPV-2a has not been reevaluated. In this study, dogs were immunized with one of 7 commercial CPV vaccines (4 modified live and 3 inactivated vaccines) followed by challenge with CPV-2a strain, KV0901 that had been isolated from naturally infected dog in 2009. All dogs vaccinated twice with 4 commercial modified live CPV vaccines were seroconverted (geometric mean HI titer > 190.2) and most of dogs were completely protected against virulent CPV-2a strain infection. The dogs inoculated with 3 commercial inactivated CPV vaccines were also seroconverted and showed a slight loss of appetite and light diarrhea for 4 days after challenge and returned to normal at 5 days post challenge. However, the non-vaccinated dogs revealed the typical clinical signs of CPV infection including haemorrhgic diarrhea. In conclusion, the 4 live CPV vaccines licensed in Korea cross-protected dogs against virulent challenge with CPV-2a and are applicalble to pet dogs for the prevention of CPV infection.

The objective of this study was to investigate the effect of a herd specific vaccine against Staphylococcus aureus (S. aureus) by different inoculation route, IMI (intramammary injection), Koso, and supramammary lymphnode area. Based on strains of S. aureus from a case of acute clinical mastitis in Daekwanryeong farm, two experimental vaccines were made, inactivated vaccine and sonicated one. To determine the antigen concentration of the vaccine, 220 ICR-mice were immunized by the intraperitoneal route with inactivated or sonicated experimental vaccines according to different schedules with 10 ICR mice as a control group. The sonicated vaccine was selected for further experiments in vaccination and the highest antibody titer in ELISA was observed at 3㎎/㎖ of the vaccine. The vaccine was administrated to 22 healthy cows at drying up. The quarter milk samples and bloods were collected before vaccination, right after parturition and 3 months postpartum. There were no significant differences among vaccination routes based on the antibody titers in serum and intramammary bacterial infections during drying up period. The antibody titer in serum of vaccinated cows was higher at parturition than 3 months postpartum but it had no statistical meaning, though decreased clinical signs and morbidity were observed. Results of this study suggest that the concept of the vaccine against S. aureus is to decreasing clinical mastitis rather than preventing the disease.

전기기기의 사용이 증가함에 따라 60Hz 전력선에서 발생되는 전자기장의 인체영향에 관한 관심이 고조되고 있다. 그와 더불어 60Hz 자기장에 의해 두통, 불면증 등 정신 신경 생리학적 증상을 호소하는 사람들이 증가하고 있다. 그러나 이러한 증상이 자기장 노출에 의한 것인지 심리적 요인 때문인지에 대하여 확실한 원인규명이 되어 있지 않다. 따라서 본 연구는 자기장 노출 시 생리학적 변화(심박수, 호흡수, 심박변이도, 뇌파의 알파, 베타파), 자각증상, 자기장 인지 여부를 동시에 측정하여 복합적으로 자각 증상 원인을 분석하는 연구를 수행하였다. 60Hz 12.5uT의 자기장을 일반인 군(16명)과 EHS 군(15명)을 대상으로 실제 노출 및 가상 노출을 하였다. 그 결과 알반인 군과 EHS 군 모두 60Hz 자기장 노출여부에 따른 생리학적 변화나 자각증상의 차이가 없었다. 또한 자기장 인지 정확도에서도 EHS 군이 일반인 군보다 인지를 잘한다고 볼 수 없었다. 그러므로 EHS 유발요인은 60Hz 자기장이 아니라 다른 심리적, 환경적 요인에 의한 것으로 사료된다.

Although several enteric viral pathogens including the porcine groups A, B and C rotaviruses (PGARV, PGBRV, and PGCRV), sapovirus (PSaV), and torovirus (PToV) are known to cause endemic diarrheas in weaning and post-weaning piglets, their precise prevalence in Korea is not clear. Therefore, we examined 1,222 diarrhea stools obtained from 627 farms during 2004～2009 by RT-PCR and/or nested PCR for evaluating their precise prevalence in Korea. PGARV was the predominant pathogen during 2004～2007 but its prevalence was markedly reduced during 2008～2009. PGBRV infections caused endemic diarrhea during 2004～2007, but was hardly detected during 2008-2009. PGCRV was detected at 27.0%, 14.5%, 42.4%, 28.8%, 7.3%, and 54.2% during each year of 2004～2009, respectively, indicating its high prevalence in Korea throughout the years. PSaV induced with high prevalence (32.4-39.2%) during 2004～2005 but its detection rate was markedly decreased during 2006～2009. PToV caused sporadic infections only during 2006 (1.0%) and 2007 (6.9%). These enteric viruses were detected in diarrhea specimens in piglets usually in combination with each other and/or together with bacterial pathogens including the Escherichia coli, Salmonella spp., Brachispira hyodysenteriae, and Lawsonia intracellularis. Infections with PGARV, PGCRV, PSaV, and PToV were more prevalent in fecal samples collected in cold seasons. These results provide important epidemiological data for the control and establishment of a surveillance system for the prevailing enteric viruses in Korea.

Desorption characteristics of waste activated carbons collected from chemicals manufacturing industries in Shiwha/Banwal industrial complex were investigated. Activated carbons were decomposed in a thermogravimetric analyzer (TGA) at 513K with heating rate of 10 ℃/min under nitrogen atmosphere. Activation energies and reaction orders for desorption, from the waste activated carbon were estimated by employing Friedman method and Freeman-Carroll method. It was found that the reaction orders of desorption in waste activated carbons were 0.27-1.69, and activation energies were 15.2-45.7 kJ/mol in Friedman method and 13.7-17.1 kJ/mol in Freeman-Carroll method.