This study was conducted to elucidate the occurrence area and the density of mosquito larvae in Eunpyeong Newtown, Seoul, Korea. Sampling of mosquito larvae was carried out 2 times using a dipping method at 130 points in august, 2014. A total of 1977.6 individuals were collected. Aedini larvae such as Stegomyia albopicta (Skuse) (=Aedes albopictus) or Hulecoeteomyia koreica (Edwards) (=Oclerotatus koreicus) were the most frequently collected than Culex spp. and the Anopheles spp. Mosquito larvae were surveyed in the street inlet (a rain drip box). The positive correlation of the larval density was found with the street inlet point with leaf mold and the depth of water. In the result of spatial statistics analysis, all points larvae collected were clustered and the tendency of spatial autocorrelation was apparent, but points over 20 individuals were dispersed. This result can be assumed that the mosquito larvae are able to occur to stagnant water in all places of this area. To control to mosquito occurrence, we think integrated methods are needed such as biological, ecological, chemical, physical control methods in various aspects.

Purpose: To asses the prevalence of refractive error in school-aged children. Methods: A total of 735 school-aged children in Jenman province were included. In all participants, visual acuity, auto Ref-Keratometer, and subjective refraction were determined. A spherical equivalent of -0.5 diopter(D) or worse was defined as myopia, +0.5D or more was defined as hyperopia, and a cylinder refraction greater than 0.75D was defined as astigmatism. Myopia was categorized as either low myopia -0.75∼ -2.00D, medium myopia -2.00 to -6.00 D or high myopia -6.00D or greater. Hyperopia was categorized as low hyperopia +0.75D to 2.00D, and medium hyperopia +2.00D or more. Results: The prevalence of presenting, spectacle corrected visual acuity of 0.5 worse eye was 28%, 48.2%. The prevalence rate of myopia, hyperopia, astigmatism were 43.7, 7.6%, 12.1%. The prevalence of myopia was the highest and followed by the prevalence of astigmatism. The prevalence of hyperopia decreased with age. Conclusion: Compared with other reported rates, the prevalence of myopia in the school-aged children of Jennam is similar to that in most places excluding the other countries, and that hyperopia is in the mid range.

Salmonellosis is a significant public health concern and a major cause of bacterial foodborne poisoning in Korea. Approximately 95% of salmonellosis cases in humans are related to the intake of contaminated food products, which mostly originate from livestock such as poultry, pigs, and cattle. To successfully develop strategies to reduce the spread of Salmonella, it is important to investigate the prevalence of Salmonella spp. isolated from food animals and meat. In Korea, the prevalence of Salmonella spp. in cattle was 1.2 2.0%, whereas in pigs it was 1.5 21%. Of all livestock and meat products analyzed, the Salmonella isolation rate was the highest in chickens (18.8 30.3%) and their meat. Antibiotic resistance is an important social issue. The frequent use of antibiotics in the livestock industry has led to increased antibiotic resistance in Salmonella isolates that are extracted from livestock, which raises serious public health concerns. To prevent the spread of antibiotic resistance, it is essential to collect data related to antibiotic-resistant Salmonella strains isolated from food animals and meat. Antibiotic resistance tests revealed that Salmonella isolated from cattle, pigs, and poultry were highly resistant to tetracycline and streptomycin. Recent studies show that the overuse of antibiotics in food animals can also affect antibiotic resistance in humans. Therefore, it is important to establish an appropriate management strategy to successfully prevent misuse of antibiotics within the Korean livestock industry.

Canine atopic dermatitis (CAD) is an allergic skin disease with characteristic clinical features associated with immunoglobulin E (IgE) antibodies. Identification of the causative allergens is the diagnostic goal, which is essential to treat and manage CAD patients. CAD is commonly associated with environmental allergens surrounding the patients. For this reason, it is important for diagnostic tests to select allergens that are related to the environment of each country and each province. There are two main allergen-specific tests, serological IgE test (SAT) and intradermal skin test (IDT). SAT did not show direct cutaneous reaction but did show serological reaction against allergens. However, SAT is simpler and more convenient than IDT in small animal practice. In this study, we selected domestically prevalent allergens for SAT, including 60 food allergens and 60 inhalant allergens, and tested eight dogs tentatively diagnosed with CAD based on Favrot’s criteria. Furthermore, IDT was performed on four dogs from the SAT group for comparison of SAT and IDT, and the results were very similar. In SAT, four types of mites (Bloomia tropicalis, Glycophagus domesticus, Euroglyphus maynei, and mite mixture 1 Korea; house dust mites), four types of molds (Botrytis cinerea, Alternaria alternata, mold fungi mixture 11, mold fungi mixture), and one type of pollen (tree pollen mix 3 Korea) induced a reaction in more than half of dogs tested. In IDT, all four dogs reacted positively to Dermatophagoides farinae, and three reacted positively to Dermatophagoides pteronyssinus and house dust. The mean agreement rate between SAT and IDT in this study was 76.3%. This is the first trial to apply local allergens for SAT in Korean veterinary medicine, and it might play an important role for diagnoses and management of animal allergic diseases.

목 적: 황반변성의 유병률 변화예측과 사회적 지표에 따른 비교를 통해서 황반변성을 일으킬 수 있는 요 인을 알리고자 한다. 방 법: 2012년에 보건복지부 산하 질병관리본부가 시행하여 발표된 국민건강영양조사 자료를 통해 2008 년에서 2012년까지의 자료를 분석하였다. 대상자는 18007명이며 SPSS(Ver12.0)를 사용하였다. 결 과: 지난 5년간 연령별 황반변성의 유병률은 40~49세 1.3%, 50~59세 4.5%, 60~69세 10.1%, 그리 고 70세 이상에서는 16.3%로 나이가 증가함에 따라 유병률이 증가하였다(p=0.00). 남성은 50~59세와 60~69세 연령층에서 5.0%의 가장 큰 유병률 차이를, 여성은 60~69세와 70세 이상의 연령층에서 7.7%의 가장 큰 유병률 차이를 나타내었다. 2012년 지역별 황반변성 유병률은 동 지역 4.2%(n=171)와 읍 지역 6.3%(n=63)(p=0.00), 교육수준별 황반변성 유병률은 초등학교 9.8%(n=113), 중학교 6.0%(n=31), 고등학교 3.0%(n=51), 그리고 대학교 1.8%(n=18)를 각각 나타내었다. 결 론: 60~69세 이후부터는 성별간의 황반변성 유병률 차이가 큰 것으로 나타났다. 이와 함께 안질환과 보건교육에 대한 기초지식이 낮은 저학력층과 농어촌에 거주하는 세대의 황반변성에 대한 적극적인 관리가 필요할 것이다.

본 연구에서는 식품에서의 L. monocytogenes에 대한 기 초자료를 제공하고자 2010년부터 2011년까지 서울지역에서 수거된 식품 총 1042건에서 L. monocytogenes를 분리 하여 항생제 감수성 검사를 하였다. 김밥 4건(0.8%), 육회 4건(2.6%), 연어제품 2건(11.1%), 돈육식품과 조리된 생선에서 각 1건씩(각5.9%, 6.3%) 총 12균주가 분리 동정되었다. 분리 균주를 20종의 항생제에 검사한 결과 대다수 항생제(16종)에 감수성을 나타내었지만 cefotetan (11균주), cefotaxime (7균주), cefepime (6균주)에서 내성을 나타냈으며 3균주에서 임상치료에 자주 사용되는 tetracycline에 대해서 내성을 나타내었다.

The objective of this study was to identify the nutritional risk factors by blood analysis, in 1,083 preschool children of age 3 to 6 years. The frequency of anemic children was 7.3% with Hb<11.1 g/dL, 29.9% with ferritin<20 ng/mL, and 16.7% with transferrin Fe saturation(%)<15%. The prevalence of anemia in these children were 12.8% for those with MCV<79 fL, and it was 71% for those with TIBC>400 μg/dL. Serum ferritin concentration was 20 ng/mL in the normal children. Thirty two percent of the children had anemia with Hb<12 g/dL, which is below the normal range of Hb. Exactly 15.4% of the children had serum Fe concentration of 60 μg/dL. The transferrin Fe saturation of the children (16.3%) was >15%. The serum ferritin concentration showed low correlations with Hb, Fe, transferrin Fe saturation, and MCV. The transferrin Fe saturation, higher Hb concentration, MCV, and Hct values were increased significantly. Consequently, iron-deficiency anaemia was thus defined as having Hb concentration <12 g/dL accompanied by ferritin concentration <20 ng/mL or Hct <33%.

The purpose of this study was to compare the validity of obesity indices among the body mass index (BMI), waist circumference (WC), and body fat percentage (BF%), and to determine which is the most useful index to predict the risk of chronic diseases of elderly people. This study was conducted as a cross-sectional study at welfare centers in Seoul. The total number of subjects was 261 (68 men and 193 women) with age ≥60 years. The distribution of obesity using 3 obesity indices in the subjects with hypertension, diabetes, or arthritis was BF%>WC>BMI in elderly men and WC>BF%>BMI in elderly women. In elderly women, odds ratios (ORs) for hypertension in BMI and WC quartiles were significantly increased in quartile 2 and 3 (p<0.05). The ORs for hypertension, hyperlipidemia, and arthritis in BF% quartiles were significantly increased in quartile 3 and 4 (p<0.05). The BF% was sensitive obesity index for predicting the occurrence of chronic disease in men, and the WC was sensitive index in women. Our results suggested maintaining BMI less than 23.5 kg/m2, WC less than 82 cm, and BF less than 35% in order to prevent chronic diseases in elderly women.

목 적: 백내장 유병률 변화와 예측을 통해 백내장의 위험성과 관리 및 예방의 중요성을 알리고자 한다. 방 법: 2008년에서부터 2012년까지 최근 5년간 보건복지부 산하 질병관리본부가 시행하여 발표한 국민건강영양조사 자료를 통계 분석하였다. 결 과: 연령별 백내장의 유병률은 40-49세 11.1%, 50-59세 35.7%, 60-69세 71.8%, 그리고 70세 이상에서는 94.2%로 나이가 증가함에 따라 유병률이 증가하였으며(p=0.00), 특히 남성 50-59세 연령층의 경우 2008년 35.7%에서 2012년 48.2%로 5년 동안 13.0%의 백내장 유병률이 증가한 것으로 나타났다. 지역별 백내장 유병률은 동 지역에서는 39.5%와 읍 지역에서는 51.1%로(p=0.00), 소득별 백내장의 유병률은 최하위 소득군 43.1%, 중하위 42.9%, 중상위 41.6% 그리고 최상위 40.7%를 각각 나타내었다. 결 론: 65세를 넘어가면 남성과 여성간의 백내장 유병률의 유의한 차이가 있는 것으로 나타났다(p=0.02). 그러나 그 차이는 계속 줄어들고 있으며 그것은 특히 50대 남성 백내장 유병률의 가파른 증가와 연관이 있음을 알 수 있다.

Purpose: To examine the relationship between working in a very dry clean room (relative humidity less than 1%) and dry eye, and its progress by lapse of time. Methods: Targeting 352 employees working in a clean room of onesecondary cell production plant, it performed a dry eye examination in 2011, 2012, and 2013, totally three times. It performed the TFBUT, Schirmer’s test,slit lamp microscope examination, and Mac Morning survey. dry eye stages were classified based on the DEWS criteria. The annual examination results were analyzed through the Anova test and the post-mortem was conducted with Tukey, and in order to learn the effect of working time on dry eye, anunivariate logistic regression analysis was conducted having dry eye examination results as a dependent variable and working time as an independent variable. Results: According to TFBUT and Mac Morning survey, dry eye degenerated as time passed. There was no change in the Schirmer’s test. Considering that as a result of the univariate logistic regression analysis having dry eye examination results as a dependent variable and working time as an independent variable, in the Mac Morning survey, the cross ratio increased up to 1.127(95%CI 1.033~1.230)by lapse of time, it could be found that as working time is elongated, the complaining rate of dry eye increases. Conclusion: It is thought that a clean room with a relative humidity less than 1% affects causing dry eye. Working time limitation, job rotation, and health care such as prescription of artificial tear solution without preserved agent are necessary.

Listeria monocytogenes continues to be a important food safety concern. The aims of the present study were to investigate the prevalence and antimicrobial susceptibility of L. monocytogenes. A total of 1,042 samples was collected from 2010 to 2011 in Seoul and twelve L. monocytogenes were isolated. Isolation rate was Gimbap (0.8%), Beef (yukhoe) (2.6%), Pork (cooked) (5.9%), Fish(cooked) (6.3%), and Salmon (11.1%), respectively. In this study, most of the isolates were susceptible to antibiotics. The most common resistance was cefotetan on 11 isolates, followed by cefotaxime on 7 isolates, cepefime on 6 isolates and tetracyclin on 3 isolates.

Most Korean beekeepers have moved from south to north of Korea to collect nectar from black locust (Robinia pseudoacacia) flowers for 2 months. This provided a valuable opportunity to sample bees originating from diverse areas in one location. We initiated a survey of honeybee (Apis mellifera) colonies on the blooming period of Acacia to determine the prevalence of Nosema apis and black queen cell virus (BQCV) in 2013. Nosema causes significant losses in population size of honeybees. Sixteenth hives were sampled for this study. Bees were collected on the 4th and 13th of May, 2013. Nosema spore counts ranged from zero to 1,948,333 spores per bee. The average number of nosema spores per bee was calculated to be 450,000. Approximately 94% of the apiaries examined were infected with nosema, based on the presence of spores in the flowering period of Acacia. Also nosema is thought to be associated with black queen cell virus. RT-PCR analysis shows that BQCV infection rate was 100%. This indicates that nosema and BQCV is the predominant species affecting honeybee colonies.

Visceral larva migrans (VLM) is a clinical syndrome caused by the migration of certain larval nematodes through the tissues of an aberrant host. VLM in humans is most frequently associated with Toxocara canis, the common roundworm of dogs. To demonstrate the prevalence of Toxocara spp. eggs in public playgrounds in Seoul city, soil samples collected from April to December in 2012 were examined. Eggs of parasite were found 4 of 1,174 in soil samples from public playgrounds and educational facilities in Seoul. Of the 1,174 soil samples examined, 0.34% of samples were found th be positive ova of Toxocara canis. Soil samples in educational facilities were more contaminated (0.57%) with the eggs than those in public playground area (0%). Most Toxocara canis eggs in sands were found in the autumn.

TM7 is an uncultivated organism which is present in ex- tremely diverse environments. Members of the Dialister genus are difficult to culture as a result of which many of these strains remain uncultivated. It has been suggested that TM7 and Dialister bacteria may belong to a group of suspected periodontal pathogens. In our current study, the presence of the sebacteria in Korean dental plaque samples was asses- sed using PCR detection methods with specific primers for 16S ribosomal RNA genes. The experimental group inclu- ded 84 volunteers (35 males and 49 females). Plaque sam- ples were collected from 4 non-adjacent proximal sites of the molar areas of the mandible in each subject and pooled. TM7 was detectable in 56% and the Dialister genus in 27.5% of the volunteers. Both TM7 and Dialister were present in 20.3% of volunteers. We found that 36.9% of the volunte e rs we re negative for both bacteria. Further s tudi e s to evaluate the prevalence of these putative pathogenic bac- te ria in the Korean population are warranted.

어린이집 유아들이 공용으로 사용하는 수건의 미생물 오염도와 분리된 식중독 미생물의 장독소 유전자 및 장독소 생산 특성을 분석하여 어린이집 유아 사용 수건의 위생 안전성을 확보하고자 어린이가 손 씻은 후 공용으로 사용 하는 수건 22개 (사용 전 7개, 사용 중 15개)를 연구대상으로 하였다. 일반세균수는 평균 6.2 log CFU/100 cm2로 검출되었고 진균수는 평균 4.1 log CFU/100 cm2로 검출되었 으며 대장균군은 사용 전 수건의 경우 7건 중 4건 (57.1%), 사용 중인 수건의 경우 15건 모두에서 (100%) 검출되었 다. 어린이 사용 수건의 미생물 오염도가 높게 나타나 수 건의 위생적인 살균 세탁 및 상대습도가 낮은 곳에 보관하는 등의 보관 방법 개선이 필요한 것으로 판단되었다. Salmonella spp.의 경우 실험에 사용된 모든 수건에서 검출되지 않았으나, Staph. aureus는 22건 중 5건 (22.7%), B. cereus는 11건 (50.0%)에서 검출되어 B. cereus 오염이 가장 심각한 것으로 나타났다. Staph. aureus 장독소 유전 자와 독소 단백질은 모두 불검출 되었으나 분리 동정된 11균주의 B. cereus 장독소 유전자 실험 결과 hblC, hblD, hblA 유전자가 각각 72.7, 72.7, 54.5% 검출되고 nheA, nheB, nheC 유전자가 각각 81.8, 72.7, 54.5% 검출되었으며 cytK, entFM 장독소 유전자는 각각 45.5, 90.0% 검출 되었다. B. cereus 장독소 실험결과 HBL 장독소는 11균주 중 8균주 (72.7%), NHE 장독소는 5균주 (45.5%) 검출되었고 HBL과 NHE 장독소 중 하나 이상을 생산하는 B. cereus 균주는 10균주 (90.9%)로 나타났다. 수건에 오염된 B. cereus 균주의 교차오염에 따른 식중독 위험성이 상존 하는 것으로 나타나 개인별 수건 또는 종이 타올 사용을 고려하여야 할 것으로 판단되었다.

목적: 본 연구는 우리나라 성인의 건강형평성 주요 척도에 따른 백내장을 분석함으로써 눈 건강 형평성을 평가하고자 하였다. 방법: 국민건강영양조사(2009) 안검진 조사 데이터를 이용하여 무수정체안을 제외한 만 20세 이상의성인7,412명을 대상으로 소득수준, 교육수준, 직업, 지역에 따른 백내장의 유병률 및 오즈비를 분석하였다. 백내장은 안과전문의가 slit-lamp를 이용하여 검사하였다. 건강형평성 주요 척도에 따른 유병률은 t-검정 및 x² 검정하였고, 오즈비(odds ratio)는 로지스틱 회귀분석을 이용하였으며, 유의수준은 0.05로 PASW18.0을 사용하여 분석하였다. 결과: 백내장의 표준화 유병률은 26.4%이었다, 유병률은 가구소득‘하’에서41.2%, ‘초졸 이하’59.9%.‘무직’53.9%,‘도시지역’62.8%이었다. 건강형평성 주요 척도에 따른 백내장의 오즈비는 50세 이상군에서 가구소득이 ‘하’일 때 2.60(CI, 196-344), ‘무직군’일 때 2.33(CI, 1.49-3.34), 농촌지역에서 1.24(CI, 0.99-1.56)로 높게 나타났다. 20-49세군은 ‘초졸 이하’에서 5.48(CI, 2.71-11.06)이었고, ‘농림어업 숙련 종사지군’에서 .33(CI, 1.37-8.10)으로 높았다. 농촌지역에서 가구소득이 ‘하’일 때 오즈비는 2.33(CI, 1.35-3.69), ‘초졸 이하’일 때 2.03(CI, 0.97-4.26), ‘단순노무 종사지군’에서 1.28(CI, 0.52-3.14)로 도시지역에 비해 높았다. 여자의 경우 가구소득이‘하’에서 1.60(CI, 1.12-2.30), ‘초졸 이하’에서 1.79(CI, 1.09-2.92)로 남자에 비해 높게 나타났다. 결론: 낮은 사회경제적 상태에서 백내장의 유병률과 오즈비가 증가하여 우리나라 성인의 눈 건강 불평등이 존재하였으며, 이를 위해 저소득층을 위한 종합적인 일차안보건의료정책이 필요하다. 또한 외국의 안보건정책과의 비교를 통해 기존의 치료 위주의 보건정책보다는 예방과 교육 중심의 보건정책의 개발이 요구된다.

본 연구는 김포시에서 모기성충의 계절적 발생소장과 얼룩날개모기류 유충의 발생을 파악하기 위해서 실시되었다. 성충모기는 6지점에서 유문등을 이용하여, 2008년 5월부터 9월까지 조사되었다. 조사결과 8속 16종 48,919마리가 채집되었다. 금빛숲모기(Aedes vexans nipponii)가 43%로 가장 많았고, 중국얼룩날개모기(Anophels sinensis)가 34%, 작은빨간집모기(Culex tritaeniorhynchus)가 14%로 이 3 우점종이 전체의 91%를 차지했다. 얼룩날개모기류의 계절적 발생소장은 작은빨간집모기와 비교하여 다른 피크를 보였다. 얼룩날개모기류 유충은 203지점 중 138지점(63%)에서 확인되었다. 지점당 정량조사 결과에서 평균유충밀도는 연꽃 재배지가 6.9개체로 가장 높았으며, 다음으로 수로가 4.5개체, 미나리꽝이 3.4개체, 유수지가 3.2개체, 휴경논이 3.1개체, 논이 1.8개체, 습지가 1.4개체, 하천이 0.2개체 순이었다. 유충밀도와 용존산소량, 산도, 염분도, 흡밀원(축사, 돈사, 계사) 사이에 유의한 관계성은 없었다. 최근린평균거리분석(ANNA)의 결과에서, 유충 조사지점간 분포패턴은 전체 조사지점간과 4.0개체 이상 확인된 지점간에서 각각 밀집분포와 불규칙분포였다. 하성면에서는 유충이 3.0 개체 이상 확인된 지점간 분산분포를 나타냈다.