본 연구는 과피색에 따른 토마토 과실의 숙성 단계에 따른 기능성 물질 및 항산화 활성의 차이를 알아보기 위해 실시하 였다. 토마토 샘플은 성숙한 단계에서 과피색이 황색, 흑색, 적 색으로 구별되는 세 가지 토마토 품종을 이용하였다. 토마토 샘플을 녹색기, 변색기, 최색기, 완숙기의 4가지 숙성 단계에 서 수확한 후 당, 라이코펜, 아스코르브산, 폴리페놀 및 항산화 활성을 포함한 다양한 생리 활성 화합물을 분석하였다. 토마 토 과실의 주요 당분은 과당과 포도당이다. 황색 토마토의 과 당과 포도당 함량은 숙성 단계에 따라 점차 증가하였다. 그러 나 흑색 토마토와 적색 토마토는 변색기 단계에서 증가한 후 상대적으로 일정하게 유지되었다. 과피색에 관계없이 모든 토마토 과실에 함유된 라이코펜 함량은 숙성 단계에 따라 크 게 증가했습니다. 라이코펜 함량은 적색 토마토 과실의 성숙 단계에서 가장 높게 관찰되었다. 황색 토마토 과실의 아스코 르브산 함량은 낮았으며 숙성 단계 동안 상대적으로 일정하게 유지되었다. 흑색 토마토 과실의 아스코르브산 함량은 성숙 단계에서 2,249mg·kg-1으로 크게 증가한 반면, 적색 토마토 과실에서는 성숙 단계에서 3,529mg·kg-1으로 점차 증가했습 니다. 페놀성 화합물인 퀘르시트린은 토마토 과실에서 발견 되었지만, 성숙 단계에서 토마토 과실의 퀘르시트린 함량은 점차적으로 감소되었다. ABTS 라디칼 소거 활성은 최색기의 황색 토마토 과실에서 급격히 증가한 반면, 흑색 토마토와 적 색 토마토에서는 숙성 단계에 따라 점진적으로 증가하였다. 모든 토마토 과실의 DPPH 라디칼 소거 활성은 최색기에서 크 게 증가했다.

Background: Forward head posture affects many individuals and can cause pain and dysfunction in the muscles and joints of the head, neck, and shoulders. Objectives: This study aimed to assess muscle activity and onset time of cervical and scapular muscles during 180° shoulder flexion and abduction in individuals with normal head posture (NHP) and in those with forward head posture (FHP), both before and after correction. Design: Cross-sectional study. Methods: Thirty-six individuals were divided into FHP and NHP groups. Muscle activity and muscle contraction onset time of the splenius capitis, sternocleidomastoid, upper middle and lower trapezius, and serratus anterior muscles were measured during shoulder flexion and abduction using wireless surface electromyography. Results: The FHP group exhibited increased muscle activity compared to the NHP group (P<.05), notably in the sternocleidomastoid and middle trapezius muscles, more so during shoulder abduction than flexion (P<.05). Regarding muscle contraction onset time, sternocleidomastoid onset was fastest during shoulder abduction in the FHP group (P<.05), while serratus anterior onset was slowest during both shoulder abduction and flexion (P<.05). Conclusion: These findings highlight distinct muscle activity and muscle contraction onset time patterns based on head posture and shoulder movement. Selective muscle activation strategies may help reduce heightened sternocleidomastoid and trapezius activity and enhance serratus anterior engagement in individuals with FHP.

Electrochemical water splitting presents an optimal approach for generating hydrogen ( H2), a highly promising alternative energy source. Nevertheless, the slow kinetics of the electrochemical oxygen evolution reaction (OER) and the exorbitant cost, limited availability, and susceptibility to oxidation of noble metal-based electrocatalysts have compelled scientists to investigate cost-effective and efficient electrocatalysts. Bimetallic nanostructured materials have been demonstrated to exhibit improved catalytic performances for the oxygen evolution reaction (OER). Herein, we report carbon aerogel (CA) decorated with different molar ratios of Fe and Ni with enhanced OER activity. Microwave irradiation was involved as a novel strategy during the synthesis process. Inductively coupled plasma mass spectrometry (ICP-MS), X-ray diffraction (XRD), X-ray Photoelectron Spectroscopy (XPS), Scanning Electron Microscope (SEM), Energy dispersive X-ray spectroscopy (EDAX spectra and EDAX mapping), Transmission Electron Microscope (TEM), High-Resolution Transmission Electron Microscope (HR-TEM), and Selected Area Electron Diffraction (SAED) were used for physical characterizations of as-prepared material. Electrochemical potential towards OER was examined through cyclic voltammetry (CV), chronoamperometry, and electrochemical impedance spectroscopy (EIS). The FeNi/CA with optimized molar ratios exhibits low overpotential 377 mV at 10 mAcm− 2, smaller Tafel slope (94.5 mV dec− 1), and high turnover frequency (1.09 s− 1 at 300 mV). Other electrocatalytic parameters were also calculated and compared with previously reported OER catalysts. Additionally, chronoamperometric studies confirmed excellent electrochemical stability, as the OER activity shows minimal change even after a stability test lasting 3600 s. Moreover, the bimetallic (Fe and Ni) carbon aerogel exhibits faster catalytic kinetics and higher conductivity than the monometallic (Fe), which was observed through EIS investigation. This research opens up possibilities for utilizing bi- or multi-metallic anchored carbon aerogel with high conductivities and exceptional electrocatalytic performances in electrochemical energy conversion.

Integration of noble metals on graphene is renowned for their catalytic and antioxidant prowess. However, utilization of toxic chemicals in the synthesis creates environmental pollution and poisonous nature of chemically synthesized materials. To address this, an economical and eco-friendly method for synthesizing graphene-gold (BRG-Au) nanocomposite by anchoring gold nanoparticles (Au NPs) onto reduced graphene oxide sheets using betel leaf extract as a reducing and stabilizing agent is presented. Comprehensive structural characterizations through UV–Visible, Raman, FT-IR, and XRD analyses confirm the successful formation of the BRG-Au nanocomposite. Morphological assessments utilizing FE-SEM and TEM techniques revealed the presence of transparent, twinkling graphene sheets embellished with 20 to 60 nm of Au NPs in various shapes, including spherical, triangular, pentagonal, circular, and trapezoids. The catalytic and antioxidant activities of the BRG-Au nanocomposite were thoroughly evaluated. In catalytic trials, the nanocomposite exhibited remarkable efficiency in the reduction of 4-nitrophenol to 4-aminophenol, accomplishing this transformation within a mere 30 min during the initial cycle and maintaining stable catalytic performance over three consecutive cycles. Additionally, antioxidant analyses employing Total Antioxidant Activity and 2,2-diphenyl-1-picrylhydrazyl methods demonstrated that BRG-Au nanocomposite possessed equal or superior antioxidant activity than the ascorbic acid standard. This research thus underscores the promising potential of environmentally benign synthesis method for graphene-gold nanocomposite with enhanced catalytic and antioxidant properties.

Sensors for monitoring human body movements have gained much attention in the recent times especially in the health-care sector as these devices offer real-time monitoring of vital physiological signs, enabling health-care professionals to evaluate health conditions and provide remote feedback. In this work, we have fabricated carbon-nanotube (CNT)/ polydimethylsiloxane (PDMS) composite sensor through simple dispersion and freezing method for monitoring flexion movements in humans. Sensors with different CNT loadings, namely 0.1 wt %, 0.5 wt %, and 1 wt % were fabricated and analyzed to find the best performing sensor. Several characterizations like Raman, X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), thermogravimetric analysis (TGA), tensile strength measurements, and piezoresistive studies were carried out to study the features of the sensors. Among the fabricated sensors, the one with the loading concentration of 0.5 wt% is found to be most sensitive for flexion applications with higher gauge factor of 533 at 60% strain level, response time of ~ 140 ms and lower hysteresis loss. The feasibility of the sensor for monitoring flexion like finger bending, wrist bending, elbow bending, and knee bending is also analyzed making it ideal for use in sports for athletes, physicians, and trainers to investigate physical performance and well-being.

Sprout products, such as broccoli, alfalfa, and cabbage, have positive health effects. Thus far, sprout foods have attracted attention owing to their good bioavailability. In particular, young broccoli sprouts exhibit anti-inflammatory, antioxidant, and anti-cancer effects. They contain 100 times more chemoprotective substances than adult broccoli. This study examined the anti-inflammatory effects of freeze-dried young sprout broccoli (FD-YB) in vitro using RAW264.7 macrophage cells. The FDYB powder antioxidant ability test showed that the radical-scavenging activity and superoxide dismutase enzyme activity increased in a dose-dependent manner. In addition, FD-YB was not cytotoxic to RAW264.7 cells, and nitric oxide production decreased after the FD-YB treatment of lipopolysaccharide-stimulated RAW264.7 cells in a dose-dependent manner. Furthermore, FD-YB significantly decreased the expression of inflammation-related proteins (Cyclooxygenase-2, Inducible nitric oxide synthase, and Prostaglandin E Synthase 2) and cytokines (Tumor necrosis factor- and Interleukin-6). In conclusion, FD-YB can be a potential nutraceutical for preventing and regulating excessive immune responses during inflammation.

Helicobacter pylori are known as a causative agent of gastritis, gastric duodenum and peptic ulcer, and gastric cancer, and multiple drug use is associated with various side effects in patients. The discovery of antibacterial substances against H. pylori from Korean resource plants is an important substitute for antibiotics. 52 species of Korean resource plants were collected and extracted with 50% ethanol, and antibacterial activity against H. pylori was measured using the disk diffusion method. The toxicity of plant extracts to human gastric adenocarcinoma(AGS) cells was measured by MTT assay, and the level of IL-8 secreted when gastric epithelial cells were inoculated with H. pylori was measured. As a result of measuring the antibacterial activity of H. pylori, antibacterial activity was confirmed in 38 plant extracts. The plant species with the strongest antibacterial activity were Chrysanthemum indicum, Rheum rhabarbarum, Patrinia scabiosaefolia and Petasites japonicus. C. indicum was not cytotoxic to H. pyroli-infected AGS cells and showed anti-inflammatory effects. This study's results can be used to develop healthy, functional foods and medical materials.

The objective of this study was to compare the feeding effects of imported timothy hay, domestic Italian ryegrass silage (IRGS) and IRG dried by hot-air dry system (IRGHDS) under basic total mixed ration (bTMR) on rumination activity, milk production, and milk composition in lactating dairy cows. Eighteen Holstein dairy cows were divided into three groups: control (bTMR + imported timothy hay), treatment 1 (bTMR + IRGS) and treatment 2 (TMR + IRGHDS) groups. The study was conducted over a total period of 24 days, including a 10 days adaptation period and a 14 days main experimental period. The results indicate body weight was not significantly different between the three groups (p>0.05), and rumination time was significantly higher in the treatment 1 group compared with the control group (p<0.001). Milk fat, protein, and lactose were not significantly different between the three groups (p>0.05), however, somatic cell counts were significantly lower in the treatment 1 group compared with the control group (p<0.001). As a result of the economic feasibility analysis, it is expected that feeding TMR using IRGS and IRGHDS will increase profit by 402.8 won/day and 331.4 won/day per cow compared to imported timothy hay. Therefore, IRGS and IRGHDS can be used as substitutes for imported timothy hay in feeding lactating dairy cows.

거북목 자세는 현대인의 대표적인 자세 변형 문제로 신체적 및 정신적으로 다양한 문제를 야기하고 있으나 거북목 자세가 휴식시 불편함이나 주의력 분산 등에 미치는 영향은 잘 알려지지 않았다. 이에 본 연구에서는 휴식시의 뇌파 신호 분석을 통하여 거북목 자세가 뇌기능에 미치는 영향을 확인하고자 한다. 본 연구에는 33명의 컴퓨터 과사용자가 참여하였고 그들은 모두 컴퓨터 사용시 기능적 거북목 자세가 나타났다. 연구참여자는 정상자세와 거북목 자세를 번갈 아 수행하도록 하였고, 각 자세를 5분 동안 유지하는 동안 자극이 주어지지 않은 상태로 휴식시 뇌파를 측정하였다. 뇌파 는 32개의 채널에서 신호를 획득하였고, 주파수 분석을 통해 불편함이나 주의력에 밀접한 관련이 있다고 알려져 있는 델타파와 베타파에 대한 자세별 변화를 비교 분석하였다. 그 결과 거북목 자세에서는 정상자세 보다 9개의 채널에서 델타파의 유의한 감소를 보였고, 14개의 채널에서는 베타파의 유의한 증가를 보여주면서 거북목 자세가 휴식시 뇌기능에 영향을 주는 것으로 나타났다. 이러한 변화는 심리적 불편감과 주의력 분산 상태에서 나타나는 변화와 일치하며 거북 목 자세의 근골격계 변화로 인해 증가된 불편함이 뇌활성에도 영향을 주기 때문으로 보인다. 이러한 결과는 자세 교정이 이루어진다면 휴식시 뇌기능과 심리 상태 개선에 도움이 될 수 있다는 것을 보여주는 중요한 결과로 평가될 수 있다.

The objective of this study was to investigate the comparison of feeding a total mixed ration (TMR) containing imported alfalfa hay and TMR containing hot-air dried domestic alfalfa on rumination activity, milk production, and composition in lactating dairy cows. Ten Holstein dairy cows were divided into two groups: control (imported alfalfa hay + TMR) and treatment (hot-air dried domestic alfalfa + TMR) groups. The study was conducted over a total period of 18 days, including a 13-days adaptation period and a 5-days main experimental period. The results indicated no differences in total digestible nutrient and net energy intake between the imported and hot-air dried alfalfa. Body weight was not significantly different between the two groups (p>0.05), however, total feed intake and rumination time were significantly and tendentially higher in the treatment group compared with control group, respectively (p<0.001; p=0.075). Milk yield was not significantly different between the two groups (p>0.05), however, milk fat (kg) and lactose (%) concentration were significantly higher in the treatment group compared with control group (p=0.016; p=0.02). This study confirms that feeding TMR with hot-air dried domestic alfalfa results in no differences of feed intake, rumination activity, and milk productivity. Therefore, it is considered that hot-air dried domestic alfalfa can be used as a substitute for imported alfalfa on lactating dairy cows.

본 연구는 미래로 나아갈수록 창의적 인재가 요구되는 사회에서 청소년의 창의성을 어떻게 발현시키고 발달시킬 것인가에 대한 건강한 정신건강과 문화예술교육의 함의를 시사하고자 하였다. 본 연구의 연구 방법은 한국교육개발 원에서 제공하는 한국교육종단연구(KELS) 패널 데이터 자료를 부분 추출하여 SPSS 23.0 프로그램을 사용하여 정신 건강과 창의성의 관계를 살펴보았고 정신건강과 창의성의 관계에서 문화활동참여 빈도, 문화예술활동 경험 각각의 매개효과를 분석하였다. 연구 결과, 정신건강과 창의성의 관계는 유의미한 정적 관계로 나타났으며 부분매개효과를 확인했고 편안함, 즐거움, 행복함의 긍정적 정신건강과 문화예술교육, 문화예술활동이 청소년의 창의성에 긍정적인 영향을 미친다는 결과를 본 연구에서 검증하였다. 따라서 청소년의 창의성 발달을 위해 마음의 편안함, 즐거움, 행복 함과 같은 심리·정서적 정신건강 증진이 우선 되어야 하며 촉진 수단의 매개로 문화예술활동에 참여하는 방법을 활용할 수 있으며 청소년 문화예술활동 경험의 활성화를 위한 지역사회와 교육 현장의 다양한 문화예술교육 프로그램 개발 및 제공은 미래 사회의 창의융합형 인재를 양성하기 위한 주요한 과제가 될 것이다.

목적: 본 연구는 인지가 건강한 지역사회 중고령자 인구를 대상으로 한 인지적 여가활동 중재연구를 분석하여 국내 지역사회 적용을 위한 근거를 마련하고자 한다. 연구방법: 본 연구에서는 2013년 1월부터 2023년 12월까지 최근 10년간 국외 학술지에 게재된 문헌을 대상으로 PRISMA 지침에 따라 문헌고찰을 진행하였다. PubMed, EMBASE, Web of Science, CINAHL, APA PsycInfo 데이터베이스를 사용하였으며, 주요 검색어로 (“elderly” OR “older*”) AND (“leisure*” OR “leisure activities”) AND (“cognitive*”AND “dementia”)를 사용하였다. 대조군이 있는 실험연구를 선정하였으며, Physiotherapy Evidence Database (PEDro) scale을 통해 선정된 문헌의 질을 평가하였다. 결과: 최종 6편의 연구 분석결과, 인지적 여가활동 중재는 악기 연주, 독서, 보드게임, 직소 퍼즐의 네 가지 범주로 구분되었으며, 악기 연주와 보드게임 중재가 각 2편으로 가장 많았다. 직소 퍼즐을 제외한 중재에서 실험군은 대조군에 비해 인지기능에서 유의한 향상을 보였으며, 이는 음운언어 및 범주언어 유창성, 언어 및 시각 작업기억, 집행기능과 억제조절, 분리주의력, 시각적 스캐닝, 전반적인 인지기능 개선을 포함한다. 또한, 여가활동 수행기술, 기분상태, 신체적 및 심리적 건강 영역에서의 삶의 질의 개선 효과도 관찰되었다. 결론: 본 연구는 일부 인지적 여가활동 중재가 지역사회 중고령층부터 고령층에 이르는 지역사회 인구의 인지기능 및 심리사회적 영역에 긍정적인 영향을 줄 수 있음을 확인하였다. 향후 작업치료 분야에서 인지 건강 강화를 위해 다양한 인지적 여가활동이 일상생활의 일부로서 적극적으로 활용되기를 기대한다.

본 연구는 노인복지관 이용 여성노인의 사회적 자본과 성공적 노화의 관계 에서 여가활동 만족이 어떠한 매개적인 역할을 하는지 검증함으로써 여성노 인의 성공적 노화를 증진 시킬 수 있는 실천 방안을 모색하는 데 있다. 본 연구는 D지역 10개 노인복지관에서 여가 프로그램을 이용하는 여성노인을 대상으로 하였으며, 최종 자료분석에는 235부를 활용하였다. 본 연구결과, 첫째, 성공적 노화에 여성노인의 사회적 자본이 미치는 영향은 유의미한 것으 로 분석되었다. 노인복지관 이용 여성노인의 사회적 자본 수준이 높을수록 성 공적 노화가 높아진다는 것을 의미한다. 둘째, 여성노인의 여가활동 만족은 사회적 자본과 성공적 노화 간 관계에서 매개효과를 가지고 있음을 알 수 있 다. 이상의 연구결과를 바탕으로 노인복지관 이용 여성노인의 사회적 자본을 증진시키고 성공적 노화의 향상을 위한 시사점을 제시하였다.

Broccoli and cabbage are known to have antioxidant, cholesterol-lowering, and anticancer effects due to their high bioactive component levels. This study applied 70% ethanol and hydrothermal extraction to separate bioactive components from broccoli and cabbage. 30oBrix extracts were freeze-dried and then diluted in various concentrations with distilled water for analysis. Total polyphenol contents, DPPH radical scavenging activity, ABTS radical scavenging activity, ferric ion reducing antioxidant power, and hydrogen peroxide scavenging activity were analyzed. The diverse antioxidant assays, except DPPH radical scavenging activity, showed that hydrothermal extracts had significantly higher activity than the 70% ethanol extracts (p<0.05). In this study, it suggested that hydrothermal extraction is relatively effective in producing broccoli and cabbage extracts. Moreover, hydrothermal extraction conditions could be low-cost and environmentally friendly.

In this study, the antioxidizing effect of 2,3-dicaffeoyl-epi-quinic acid (DEQA) was investigated. The antioxidant activity was evaluated by measuring the scavenging effect on DPPH radical and peroxynitrite and the reducing power on ferric ion. DEQA showed a scavenging effect and reducing power comparable to vitamin C used as a positive control. Also, DEQA effectively inhibited production of intracellular reactive oxygen species (ROS) in HT-1080 cells, showing the scavenging ratio of 43.8% even at 10 μM concentration of DEQA after 2 hours in HT-1080 treated with H2O2. In addition to this, DEQA inhibited the production of nitric oxide (NO) very effectively in Raw 264.7 cells. The above results suggest that DEQA has the potential to be developed as a natural antioxidant.

The objective of this study was to determine the ultrasonication-assisted extraction conditions that maximize the DPPH radical scavenging activity of extracts obtained from the stems of Lespedeza bicolor Turcz through the application of the Response Surface Methodology (RSM). Before delving into the analysis of extraction conditions using the RSM model, we conducted efficiency validation of ultrasonication-assisted extraction and executed single-factor experiments for ethanol concentration, extraction time, and extraction temperature. The data obtained from these single-factor experiments were employed to construct the Box-Behnken Design (BBD). In these results, in the single-factor experiments, it was evident that the parameters for ethanol concentration, extraction time, and extraction temperature exhibited quadratic trends. The single-factor experiments allowed us to discern the trends for each parameter leading to the maximum antioxidant capacity, and this data was subsequently applied to the BBD. Following the completion of initial experiments, a Response Surface Methodology (RSM) model was constructed based on Box-Behnken Design (BBD). According to the predictive model developed in this study, it was anticipated that performing ultrasonic-assisted extraction for 85.0412 minutes at an ethanol concentration of 32.573% and an extraction temperature of 51.5608°C will result in a DPPH radical scavenging activity of 79.7146%. The predictive results were statistically verified through a comparative analysis with actual measurements and ANOVA analysis, confirming the statistical significance of the model. The finding of this study underscore the significance of optimizing extraction conditions in the precise quantification of the antioxidant potential for economic advantages in both experimental and industrial contexts.

Background: Individuals with pes planus tend to overuse the extrinsic foot muscles, such as the tibialis anterior (TA) and peroneus longus (PL), to compensate for the weakened intrinsic foot muscles, such as the abductor hallucis (AbdH). Furthermore, differences in weight-bearing can affect the activity of muscles in both the intrinsic and extrinsic foot muscles. To date, no study has compared the effects of the short foot exercise (SFE) and toe spread-out exercise (TSO) on intrinsic and extrinsic foot muscle activity and the corresponding ratios in different weight-bearing positions. Objects: To compare the effects of the SFE and TSO on AbdH, TA, and PL activity and the AbdH/TA and AbdH/PL activity ratios in the sitting and standing positions in individuals with pes planus. Methods: Twenty participants with pes planus were recruited. Surface electromyography was used to assess the amplitudes of AbdH, TA, and PL activity. Participants performed both exercises while adopting both the sitting and standing positions. Results: No significant interaction between exercise and position was found regarding the activity of any muscle or ratio of the activity, except for PL activity. We observed a significant increase in AbdH activity during the TSO compared to the SFE, and no significant difference in TA and PL activity between the two exercises. AbdH, TA, and PL activity were significantly higher in the standing position than in the sitting position. Furthermore, the AbdH/PL activity ratio significantly increased in the sitting position, although there was a significant increase in AbdH activity in the standing position. Conclusion: In individuals with pes planus, we recommend performing the TSO in the sitting position, which may increase the activity of the AbdH while concurrently decreasing the activity of the TA and PL, thus strengthening the AbdH.