This study aimed to evaluate the changes in the content of functional components and antioxidant activity of rice and barley according to the milling process used. A considerable amount of γ-oryzanol was observed in unmilled rice and barley. However, γ-oryzanol was not detected in the rice and barley after the milling process. The highest content of γ-aminobutyric acid (GABA) was observed in the unmilled Keunalbori-1-ho barley. The contents of biotin in all samples also decreased in the milled grains compared to the unmilled grains. The highest content of total polyphenols and flavonoids was observed in the Heuksujeongchal barley, and the highest radical scavenging activity was also found in this grain. The milling process led to a decrease in the content of functional components, including γ-oryzanol, GABA, biotin, polyphenols, and flavonoids in both rice and barley. These results may be useful in the development of processed foods using cereal grains.

One of the most demanded competencies of an oral health professional such as an oral pathologist is the ability to make clinical decisions. The purpose of this study was to examine the neurological differences between beginners and experts in the clinical decision-making process which consisting of complex, dynamic and sophisticated cognitive processes, and to identify the characteristics of experts based on the brain by comparing EEG activity. This study conducted experimental design with 10 dentists with more than 10 years of clinical experience and 10 students with short clinical experience as beginners as a fourth year student before graduation. The hypothesis-oriented algorithm proposed in HOAC II was used. As a standard, the clinical decision-making stage of the dentist was divided into three stages, and an event was developed and an experiment was designed for measuring EEG for each stage. The cerebral activity distribution patterns of the two groups were measured with EEG, compared and analyzed with pre-processing process using EEGlab. As a result, the difference in the auditory information was not noticeable between the novice and the expert, but the difference between the group of the novice and the expert appeared in the visual data and the radiographic data. In the case of beginners, the activity was higher in the left hemisphere, and in the case of experts, both brains were activated. The results of this study are intended to present objective information based on brain-based analysis of differences that appear in the clinical decision-making process of experts and beginners. It can be used as basic research data to present the brain-based characteristic analysis of dentist experts.

A facile one-pot wet chemical process to prepare pure anatase TiO2 hollow structures using ammonium hexafluorotitanate as a precursor is developed. By defining the formic acid ratio, we fabricate TiO2 hollow structures containing fluorine on the surface. The TiO2 hollow sphere is composed of an anatase phase containing fluorine by various analytical techniques. A possible formation mechanism for the obtained hollow samples by self-transformation and Ostwald ripening is proposed. The TiO2 hollow structures containing fluorine exhibits 1.2 - 2.7 times higher performance than their counterparts in photocatalytic activity. The enhanced photocatalytic activity of the TiO2 hollow structures is attributed to the combined effects of high crystallinity, specific surface area (62 m2g-1), and the advantage of surface fluorine ions (at 8%) having strong electron-withdrawing ability of the surface ≡ Ti-F groups reduces the recombination of photogenerated electrons and holes.

목적 : 본 연구의 목적은 활동분석과 프로세스 맵핑을 기반으로 한 Korean version of Modified Barthel Index(K-MBI) 가이드북을 제작하여 내용 타당도와 평가자 간 신뢰도 및 일치도를 확인하고자 하였다. 연구방법 : 본 연구에서는 활동분석과 프로세스 맵핑을 기반으로 한 K-MBI 가이드북을 개발하였다. 개발 된 K-MBI 가이드북에 대한 이해도 조사 및 수정을 하여 최종 가이드북을 제작하여 40명의 작업치료 전문가 집단에 내용 타당도를 검증하였다. 평가자 간 신뢰도 및 일치도 조사를 위해 기존의 K-MBI 검 사 지침에 근거하여 총 5명의 환자의 일상생활활동 동영상을 촬영하였다. 평가자 간 신뢰도와 일치도 조 사는 84명의 작업치료사가 교육 전과 후에 동일하게 동영상 속의 5명의 환자를 평가하여 확인하였다. 결과 : 내용 타당도 검증 결과는 개발된 K-MBI 가이드북 11개의 모든 항목에서 CVI 점수가 .93 이상으 로 높은 수준의 타당도를 나타내었다. 평가자 간 신뢰도에서는 ICC가 교육 전 .983, 교육 후에 .982로 교육 전과 후 모두 높은 수준의 신뢰도를 보였다. 정답률의 변화는 교육 전 48.37%에서 교육 후에 69.48%로 향상되었고, 평가자 간 일치도는 옷 입고 벗기 항목을 제외한 모든 항목에서 일치도가 향상 된 것으로 나타났다. 결론 : 본 연구의 결과를 통해 활동분석 및 프로세스 맵핑을 기반으로 한 K-MBI 가이드북은 일상생활활 동 평가에서 평가자 간의 신뢰도와 일치도를 향상되게 시키는 것으로 확인되었다.

This paper reviews an implementation strategy of activity breakdown for the assessment of process time. In addition, the study proposes the classification models for estimating the process time of Time-Driven Activity-Based Costing (TDABC) based on various types of activity breakdown structures, including activity interface perspective, activity decomposition perspective and activity priority perspective.

This study was conducted to develop HTHP ginseng (high temperature and high pressure ginseng) with improved antioxidative activity and phenolic acid composition by high temperature and high pressure process. The HTHP ginseng extract was analyzed for the total phenol content, DPPH radical scavenging activity and phenolic acid composition. The total phenol content was increased in HTHP ginseng (14.76 ㎎/g) compared to raw ginseng (3.59 ㎎/g) and red ginseng (3.93 ㎎/g). DPPH radical scavenging activities of HTHP ginseng, raw ginseng and red ginseng extracts were 4.8～78.4%, 1～47.4% and 1.8～56.5% at 1～100 ㎎/㎖ concentration. Also ABTS radical scavenging activities of HTHP ginseng, raw ginseng and red ginseng extracts were 8.9～99.8%, 3.4～96% and 1.2～96.5% at 1～100 ㎎/㎖ concentration. In HPLC analysis, amounts of measured phenolic acid of HTHP ginseng greatly increased than raw ginseng and red ginseng, but salicylic acid was not detected in HTHP ginseng. In addition, DPPH radical scavenging activity of phenolic acid from HTHP ginseng was increased. Consequently, we believe high temperature and high pressure process is better method than existing method to increase the bioactivity of ginseng.

Rhodiola sachalinensis fermentates by lactic acid bacteria were prepared using the adsorption process, and were investigated for changes of the main compounds and anti-oxidative activities during the adsorption and fermentation process. While the R. sachalinensis extract (RSE), which did not go through the adsorption process, showed little change in pH during fermentation and a significant reduction in the number of lactic acid bacteria, the pre-preparatory adsorption process was found to be helpful for promoting fermentation and for maintenance of bacterial numbers. The contents of total phenolic compounds mostly decreased during the adsorption process, but showed an increasing tendency to rebound during the fermentation process. The contents of salidroside and p-tyrosol in the RSE were 1153.3 ㎎% and 185.0 ㎎% respectively, and they did not significantly change after treatment with acid clay or bentonite as adsorbents, which were 1093.0 and 190.5 ㎎% by acid clay, and 882.2 and 157.3 ㎎% by bentonite. When the extract was fermented after treatment with acid clay or bentonite, the salidroside contents were decreased by 282.7 and 505.0 ㎎% respectively, but the p-tyrosol contents were increased by 714.0 and 522.4 ㎎% respectively. Compared to the DPPH radical scavenging activity of the RSE (66.8%) at the conc. of 0.1%, that of the fermented RSE, which went through adsorption process with acid clay or bentonite, was significantly increased to 79.4 and 72.7% respectively at the same concentration (p<0.05). Though fermentation by lactic acid bacteria was suppressed in the RSE, the results suggested that the adsorption process may promote fermentation without any change in the content of major active compounds. It is expected that fermentation by lactic acid bacteria could improve the antioxidant activity and various associated functionalities of R. sachalinensis.

홍삼에서 사포닌 추출과정 중 부산물로 얻어지는 홍삼오일의 화학적 특성 및 화장품소재로서의 응용가능성을 알아보고자 하였다. Tween 80으로 희석한 1% 홍삼오일의 산가는 0.265, 과산화물가는 0.387, 요오드가는 0.64이었다. DPPH free radical scavenging assay 결과, 1% 홍삼오일은 대조군인 동일 농도의 α-tocopherol에 비해 70% 정도의 항산화능을 나타내었다. 홍삼오일의 total polyphenol 함량은 243 mg/100 g이었다. Tyrosinase저해 활성을 측정한 결과, 홍삼오일은 대조군인 L-ascorbic acid에 비해 14% 정도의 활성억제 효과를 나타내었다. 홍삼오일에 의한 elastase 활성억제 효과는 거의 없었으며 홍삼오일의 Staphylococcus aureus와 Escherichia coli 에 대한 생육억제 효과도 없었다.

이 연구의 목적은 중등 학교 과학 실험 수업의 실태를 파악하기 위해 수업을 분석하는 것이다. 이를 위해 중등학교 과학 실험 수업을 세 범주로 분석하도록 개발된 분석 도구를 활용하였다. 이 분석 도구는 실험의 목적, 상호 작용, 탐구 과정 세 가지 영역에 20가지 평가 항목으로 구성되어 있으며, 4명의 과학 교육 전문가로부터 0.89의 타당도가 확보되었다. 수업 분석을 위하여 21차시의 실험 수업이 녹화되고 전사되었다. 전사된 프로토콜과 동영상을 바탕으로 실험 수업을 분석한 결과, 중등 학교 실험 수업은 실험 목적 측면에서 선언적 지식의 습득과 과학에 대한 태도의 향상에 집중되어 있었다. 상호 작용 측면은 교사의 발문이 학생들의 발산적 사고를 유도하지 못하고 있고 학생들에 의한 주도적인 실험 기회가 주어지는 대신 교사의 직접적 지도에 의해 실험 수업이 진행되고 있으며, 학생들의 토의 과정이 거의 나타나지 않는 등 상호 작용 I 수준으로 분석되었다. 탐구 과정은 학습 주제에 대한 현상 제시 및 문제 제기가 거의 관찰되지 않았다. 학생들의 가설 설정 활동이나 예상 활동도 대부분의 수업에서 관찰되지 않았으며, 실험 설계 부분은 활동지나 교사의 지시에 의해 주어지고 있었고, 학생들은 실험 결과 기록에만 집중되어 있어 탐구 과정 수준도 I 수준으로 나타났다.

This paper was concerned about case study for preventing WMDSs(Work-related Musculoskeletal Disorders) by using Thinking Process of TOC(Theory Of Constraints), Unfortunately, the number of WMDSs are rising steadily in auto-part manufacturer. These WMDSs have on worse and worse influence not only on the competition of enterprise but on the life quality of a worker. The research results are helpful to establish the preventing WMDSs and improvement of workplace environments for small-medium sized auto-part company.

석탄과 철광석은 산업발달의 시작부터 현재까지 지속적으로 사용되고 있다. 이에 따라 수반된 석탄 및 철광석 정제산업의 발달은 석탄철광폐수의 양적 증가를 초래하여 그 처리가 많은 관심 속에 활발하게 연구되고 있다. 석탄철광폐수는 페놀, 시안과 같은 독성 물질 뿐 만 아니라 혐기성미생물과 경쟁관계에 있는 황산염환원균활성증가를 초래하는 SO42-를 고농도로 함유한다. 이 석탄철광폐수의 처리법으로는 물리적, 화학적, 생물학적 처리가 다양하게 연구되어왔는데, 고농도의 폐수처리에 익히 알려진 혐기성미생물을 이용한 석탄철광폐수의 처리는 경제성과 재생에너지 측면에서 최근 큰 관심을 받고 있다. 하지만 폐수에 함유된 페놀, 시안, 등과 같은 독성물질이 생물학적 처리에 심각한 저해를 초래할 수 있어 문제로 지적되고 있으나 그 독성에 대한 현재까지의 연구는 미진한 형편이다. 이에 본 연구는 입상 혐기성미생물이 석탄철광폐수 소화 시 받게 되는 급성독성에 대하여 실험적 고찰을 진행하고 그 적응 방안을 연구하였다. 석탄철광폐수는 석탄철광정제의 완료시점에 실폐수 샘플을 채취하여 사용하였다. 폐수특성 분석결과 pH 7, 페놀 589±23 mg/L, 시안 49 mg/L, 암모니아성질소 39±9 mg/L, SO4-2는 735 mg/L이며 화학적 산소요구량은 3.9 g/L으로 나타났다. 석탄철광폐수에 대한 물벼룩 급성독성시험 결과 TU가 28로 매우 높게 측정되었다. 이 폐수에 UASB의 입상슬러지를 이용하여 혐기성소화를 수행하였다. 약 20일간 유기물 부하 0.6 g COD/L/day에서 초기 적응을 수행하였고, 혐기성소화조의 정상상태에서 COD 제거율은 98%, 메탄수율은 약 80 mL CH4/g COD로 나타났다. 이 혐기성소화조가 석탄철광폐수 유기물부하 0.76 g COD/L/day에 노출 되었을 경우 미생물의 활성을 모니터링한 결과, 폐수유입 즉시 메탄가스발생이 80% 이상 감소되는 강한 독성이 감지되었으며 COD 제거효율은 점차 감소하여 약 20일 후 10%로 낮아졌다. 유출수 내 페놀은 약 210 mg/L로 제거율 60%을 나타났지만 시안은 106 mg/L로 분해되지 않고 축적되어 유입 대비 2배가량 증가하였다. SO4-2 는 2000 mg/L로 급격하게 농도가 증가한 후 약 20일 후 1000 mg/L 이하로 감소하였다. 이로보아 석탄철광폐수 내 시안과 황화합물로 인하여 혐기성미생물 내의 메탄균의 저해가 이루어짐을 짐작할 수 있다. VFA 분석결과는 산발효균과 메탄발효균의 공생관계가 파괴되었음을 보여주었다. 더불어 높은 SO4-2 농도는 황산염환원균과의 경쟁이 유도될 수 있는 농도로 밝혀졌다. 이러한 석탄철광폐수의 급성독성은 고농도의 독성물질 제거를 위한 전처리 혹은 혐기성미생물의 적응기간이 필요함을 나타내었으며, 후자를 선택하여 약 30일 간 단계적인 미생물의 독성적응절차를 거친 결과 급성독성을 극복하고 유기물 및 페놀 분해가 점진적으로 가능함을 확인 하였다.

This study was conducted to analyze the muscle activity in the right forearm and shoulderwhile doing the sowing activity by muscle type and work section, and to find the possibility of the utilization of sowing as a muscle exercise and rehabilitative activity based on the results of the analysis. The results showed that the activity of 7 muscles including the upper trapezius near the neck, the upper trapezius near the shoulder, the middle deltoid, the biceps brachii, the triceps brachii, the brachioradialis, and the flexor carpi ulnaris were significantly higher than the stable state. In addition, the muscle activity in the sections of mixing the soil, filling the tray with the soil, sowing, writing the label, and watering was significantly higher than the stable state. In particular, the muscle activity of the biceps brachii and the triceps brachii was statistically significantly high in the section of filling the tray with the soil, which indicates that the task of filling the tray with the soil can be utilized as an exercise to activate the biceps brachii and the triceps brachii. In addition, the muscle activity of the brachioradialis was significantly high in all the work sections, which indicates that the sowing process can be utilized to exercise the brachioradialis in particular. These results can be used as the basic data about the activated muscle types and degrees throughout the sowing process. These results can be also used to induce the activation of specific muscles, and the overall exercise and rehabilitation of the forearms.

Background: We investigated the optimal aqueous extraction conditions for recovery of high yields of total phenolic compounds from roots of Arctium lappa L. (burdock, Asteraceae), and we compared their antioxidant capacity.Methods and Results: The antioxidant activity of the extracts was tested using 2,2-diphenyl-1-picrylhydrazyl, 2,2’-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid)-diammonium salt, and oxygen radical absorbance capacity assays. In addition, the major phenolic compounds present in the extracts were determined by high performance liquid chromatography analysis. Our results suggest that the roasted burdock 100°C, 15 min extract exhibited the strongest radical scavenging activity and possessed the highest concentration of phenolic compounds. The polyphenol content of both dried burdock and roasted burdock significantly increased with increase in the extraction temperature and time.Conclusions: These results indicated a relationship between phenolic compound levels in burdock and their free radical scavenging activities. This suggests that phenolic compounds significantly increase the antioxidant potential of burdock extracts.

Purpose: This study tested the health action process approach (HAPA) as a motivational model for physical activity in a longitudinal sample of 483 adults (275 males, 208 females) over a 10 week period. Methods: Participants' action self-efficacy, decision balance for exercise, perceived risk awareness and intention were measured at baseline (Time 1). Maintenance self-efficacy, action planning and action control were measured 5 weeks later (Time 2). Physical activity behavior was measured 10 weeks after baseline (Time 3). Structural equation modeling was used to investigate the HAPA model. Results: The first model showed that intention was a significant predictor of physical activity behavior. The second model, which included the volitional components of the HAPA model, did significantly increased the proportion of behavior explained. The third model showed that intention, maintenance self-efficacy and action control were positive predictors of physical activity behavior. Conclusion: Findings suggest that HAPA provides a useful framework for identifying determinants of physical activity intention and behavior within a group of middle-aged adults.

Schisandra chinensis (Sc), a species of the family Schisandraceae used fruits as medicinal herbs. In the study, we performed to determine a comparison of antioxidant activity from Sc water extracts depending on stir-frying and stir-frying with liquids by 30% ethanol pretreatments. The contents of polyphenol and flavonoid, DPPH radical scavenging, ABTS radical scavenging and reducing power activity were measured to evaluate the antioxidant activity. Total polyphenol and flavonoid contents of Sc extracts were increased in stir-frying and 30% ethanol stir-frying pretreatments compared to a control. In particular, contents of stir-frying pretreatments Sc were highest increased at 220℃ treatments. The DPPH radical scavenging activity were highest increased in stir-frying pretreatments at 220℃. And result that measurement of the ABTS radical scavenging, it showed higher activity in 30% ethanol stir-frying pretreatments at 180℃ and 220℃. But Sc in the 140℃ showed higher activity in stir-frying pretreatments. In the reducing power activity, stir-frying pretreatments increased higher than 30% ethanol stir-frying pretreatments at 220℃. As in results, antioxidant activity of Sc water extracts in stir-frying and stir-frying with liquids process increased higher than a control, and it was most effectively in stir-frying pretreatments at 220℃.

This study was to investigate the improvement of immune activities of the extracts from Codonopsis lan-ceolata by stepwise steaming process and high pressure process. The phenol contents was 8.742㎍/㎎ which was higher thanthat from conventional extraction using 70% ethyl alcohol at 80℃ for 24hours. All of extracts at a concentration of 1.0㎎/㎖showed relatively low cytotoxicity on human normal kidney cell (HEK293) in range of 16 19%. The immune B and T cellgrowth was improved by extracts using the steamed and high pressure precess of C. lanceolata up to 180×10⁴cells/㎖ and96×10⁴cells/㎖, respectively. The extract prepared also greatly increased the secretion of both IL-6 and TNF-α from thestepwise steamed and high pressure process. This results can conclude that stepwise steamed and high pressure processeffectively released active biomaterials which could important role in enhancing immune activity in the body.