Ainsliaea acerifolia leaves are registered with the Ministry of Food and Drug Safety as edible herbal materials in Korea, and research is underway to explore their potential in developing functional foods, cosmetics, and pharmaceuticals. In this study, we developed an analytical method using HPLC-DAD to quantify three key compounds—chlorogenic acid, isochlorogenic acid A, and 1,5-dicaffeoylquinic acid—in A. acerifolia leaves extract. This method has been optimized and validated for specificity, accuracy, precision, limit of quantification (LOQ), and linearity. The correlation coefficients (r²) for the calibration curves exceeded 0.9962. The limits of detection (LOD) and quantification (LOQ) were 0.3012 and 0.9128 μg/mL for chlorogenic acid, 0.1182 and 0.3582 μg/mL for isochlorogenic acid A, and 0.2342 and 0.7098 μg/mL for 1,5-dicaffeoylquinic acid, respectively. The net recovery rates for accuracy testing were 105.13% for chlorogenic acid, 105.37% for isochlorogenic acid A, and 100.37% for 1,5-dicaffeoylquinic acid. All parameters assessed with this newly developed method fell within the acceptable ranges specified by ICH guidelines. These findings demonstrate that the method is robust and reliable for accurately identifying and quantifying chlorogenic acid, isochlorogenic acid A, and 1,5-dicaffeoylquinic acid in both routine analysis and large-scale extraction process of A. acerifolia leaves.

과거 교통에서는 이동의 신속성이 중시되고 자동차의 통행이 우선이었던 반면, 현재는 모든 교통 이용자의 안전한 이동과 보행자가 중요시되는 방향으로 교통정책이 나아가고 있다. 보행자의 안전하고 쾌적한 통행과 교통약자의 이동권의 보장이 강조됨에 따라서, 향 후 교통약자 보호구역의 역할도 확대될 것으로 예상된다. 그러나 교통약자의 안전한 보행 공간 확보와 보행사고 피해의 축소라는 목 적과 달리, 스쿨존 내 사고 등은 지속적으로 발생하고 있는 추세이다. 이에 본 연구에서는 보호구역의 사고 위험을 판단하고 안전성을 분석하고자 하였다. 교통사고의 위험성을 비교하고 사고 예방이 필요한 보호구역을 판단하기 위한 기준으로서 사고 위험도를 정량화 하였다. 서울시 보호구역 내 사고 데이터를 보호구역 구간별 특성 데이터와 결합하여 구간별 사고 건수 및 피해 정도를 자료화하고, 도로 속성을 기준으로 보호구역 구간을 유형화하였다. 보호구역 유형별 사고 발생확률과 평균 피해 정도를 구해 도로의 속성마다 다 른 사고 발생 특성을 반영하였다. 사고 위험도는 사고 발생빈도와 피해 정도를 통해 판단하고자 하였다. 사고 발생빈도는 도로 면적과 발생 건수를 기준으로 하여 산출하였고, 피해 정도는 유형에 따른 사고 발생확률과 발생빈도, 평균 피해 정도를 통해 산출하였다. 위 험도에 대한 정량적 분석모델을 통해 사고 위험이 높다고 판단되는 보호구역과 해당 구간의 특성을 알아보고, 각 행정구역별로 보호 구역에서의 교통사고 위험성을 비교하였다. 이를 통해 사고 위험이 높은 지역과 유형이 무엇이며, 어떠한 특성을 보이는지 파악하여 보호구역 개선 방향을 제시하고자 한다.

This study quantitatively analyzes risks of industrial incidents to fisher on overseas tuna purse seiners and long liners. A Bayesian network is employed to analyze 478 cases of industrial incidents, comprising 401 cases from purse seiners and 77 cases from long liners, reported from 2019 to 2022. The highest risk of industrial incidents on purse seiners is attributed to diseases. Excluding diseases, risks are the highest during fishing: 5.31 times higher during catch handling, 2.05 times higher during maintenance, and 2.38 times higher during loading and unloading. The risk of industrial incidents caused by the hull is 9.50 times higher than those caused by fishing gear, 4.59 times higher than those caused by machinery, and 3.61 times higher than those caused by the caught fish. Among the types of industrial incidents, slips are the highest: 2.58 times higher than industrial incidents caused by being bump, 3.74 times higher than those caused by hit, and 3.94 times higher than those caused by imbalance and overexertion. For long liners, most industrial incidents are concentrated in diseases, with dental, musculoskeletal, skin, and respiratory diseases being the primary types of industrial incidents identified. This study aims to propose reduction measures for reducing the high-risk form of industrial incidents, specifically slips, and to present health management strategies for preventing diseases among fisher on overseas tuna fishing vessels. By addressing these aspects, this study seeks to contribute to the safety and sustainability of the overseas tuna fishing industry.

본 연구는 Diode Array Detector (DAD)가 장착된 고성능 액체 크로마토그래피(HPLC)를 이용하여 산초나무 잎에 함유된 chlorogenic acid와 hesperidin을 동시에 분석할 수 있는 표준 정량법 개발을 확립하고자 실시하였다. 산초나무 잎의 chlorogenic acid와 hesperidin은 MS/MS 분석 및 표준물질과의 유지시간(RT), UV 흡광도 비교를 통해 확인하였고, 산초나무 잎의 지표물질로 선정하였다. 개발한 분석방법은 지표물질을 대상으로 특이성, 정확성, 정밀도, 검출한계, 정량한계, 선형성에 대해 최적화하고 검증하였다. HPLC 분석으로 두 화합물에 대한 검량선은 각각 0.99% 이상의 높은 상관계수(r2)를 보였다. Chlorogenic acid의 전체 회수율은 106.82%이었고, hesperidin의 전체 회수율은 107.37%였다. Chlorogenic acid의 검출한계(LOD)는 0.271μg/ml, Hesperidin의 검출한계(LOD)는 0.005μg/ml였다. Chlorogenic acid의 일간정밀도는 0.102% (RSD%), Hesperidin의 일간정밀도는 1.038% (RSD%)였다. 본 연구에서 개발한 HPLC-DAD 분석방법은 기능성 원료 인정을 위한 분석기준을 충족하였다. 따라서 본 연구에서 확립한 HPLC 분석법은 향후 산초나무 잎에서 유래한 생리활성물질의 대량추출 및 관련제품을 개발할 때 원료 표준화에 적용가능할 것이다.

This study employs Bayesian network analysis to quantitatively evaluate the risk of incidents in trap boats, utilizing accident compensation approval data spanning from 2018 to 2022. With a dataset comprising 1,635 incidents, the analysis reveals a mortality risk of approximately 0.011 across the entire trap boat. The study significantly identifies variations in incident risks contingent upon fishing area and fishing processes. Specifically, incidents are approximately 1.22 times more likely to occur in coastal compared to offshore, and the risk during fishing processes outweighs that during maintenance operations by a factor of approximately 23.20. Furthermore, a detailed examination of incident types reveals varying incidence rates. Trip/slip incidents, for instance, are approximately 1.36 times more prevalent than bump/hit incidents, 1.58 times more than stuck incidents, and a substantial 5.17 times more than fall incidents. The study concludes by providing inferred mortality risks for 16 distinct scenarios, incorporating fishing areas, processes, and incident types. This foundational data offers a tailored approach to risk mitigation, enabling proactive measures suited to specific circumstances and occurrence types in the trap boat industry.

본 연구에서는 형광측정기법을 사용하여 태안반도 인근 8지점의 표층 해수 내 미세플라스틱 정량분포를 조사하였다. 연구결과 미세플라스틱의 검출범위는 0~360.5 particles/l (평균 149.7 ± 46.0 particles/l)로 나타났다. 하지만 해양환경 내 미세플라스틱의 정량분석방법이 표준화되지 않아 타 연구결과와 직접비교 하는 것이 불가능한 상황이다. 본 연구결과 검출된 미세플라스 틱을 크기별로 분류하면 < 50 μm 크기가 우점하지만, St. 3의 경우 > 500 μm이 25.6%를 차 지하여 지역별로 우점하는 미세플라스틱의 크기에 차이가 나타난다. 또한 채집지역, 저질의 종 류, 검출되는 플라스틱 크기에 따른 미세플라스틱의 검출량 비교에도 뚜렷한 상관관계를 가지 는 요인을 확인할 수 없었다. 이는 플라스틱의 재질에 따른 물리 · 화학적 특성, 해양의 동적 조건(해류, 바람, 파도, 조류 등), 지질학적 특성(지형, 경사 등), 연안 생물을 포함한 저질의 구성 및 특성, 상호작용, 인간활동(어업, 개발, 관광 등), 기상조건(홍수, 강우 등)과 같은 다양한 요인 이 미세플라스틱의 거동에 영향을 주기 때문이다. 그러므로 향후 정량분석방법 표준화 및 환 경요인에 대한 분석이 수반된 미세플라스틱 모니터링 기초연구가 필요한 상황이다.

Since 1992, various numerical codes, such as TOUGH-FLAC and ROCMAS, have been developed and validated to dispose of Spent Nuclear Fuel (SNF) safely through a series of DEvelopment of COupled models and their VALidation against EXperiments (DECOVALEX) projects. These codes have been developed using different approaches, such as general two-phase flow and Richards’ flow which is an approximated approach neglecting gas pressure change, to implement the same multiphysics behaviors. However, the quantitative analysis for numerical results, which originated from different fundamental approaches, has not been conducted accurately. As a result, improper utilization of the approach to analyze certain conditions occurring such as dramatic gas pressure change may result in erroneous outcomes and systemic problem pertaining to TH analysis. In this study, the quantitative analysis of the two approaches, in terms of TH behavior, was conducted by comparing them with a 1D simulation of the CTF1 experiment carried out by laboratory experiment. The results calculated by different approaches show agreement in terms of TH behaviors and material properties change until 120°C. The results verify the applicability of Richards’ flow approach in a high temperature environment above the current thermal criteria, set as 100°C, and gas pressure change does not have a significant impact until 120°C. Therefore, although further studies for applicability of Richards’ flow are needed to suggest the appropriate temperature range, these quantitative analyses may contribute to the performance assessment of a compact repository using the high-temperature bentonite concept, which is currently gaining attention.

This study aims to promote the necessity for future research from the perspective of the indoor environment by analyzing the trend of domestic COVID-19 confirmed cases and examining previous quantitative research cases. The limitations of the qualitative management plan were identified by analyzing the trend of confirmed cases and deaths in Korea and the trend before and after the implementation of 'social distancing' and 'step-by-step daily recovery', which are actually being applied. The trend of initial and follow-up measures for the outbreak of infectious diseases in Korea is judged to be a case where the importance of qualitative and quantitative management should be confirmed to prepare absolute quarantine measures. The results suggest that examining previous research cases and preparing through advanced research for effective application.

The interest in greenhouse gases (GHG) emitted from all industries is emerging as a very important issue worldwide. This is affecting not only the global warming, but also the environmentally friendly competitiveness of the industry. The fisheries sector is increasingly interested in greenhouse gas emissions also due to the Paris Climate Agreement in 2015. Korean industry and government are also making a number of effort to reduce greenhouse gas emissions so far, but the effort to reduce GHG in the fishery sector is insufficient compared to other fields. Especially, the investigation on the GHG emissions from Korean fisheries did not carry out extensively. The studies on GHG emissions from Korean fishery are most likely dealt with the GHG emissions by fishery classification so far. However, the forthcoming research related to GHG emissions from fisheries is needed to evaluate the GHG emission level by species to prepare the adoption of Environmental labels and declarations (ISO 14020). The purpose of this research is to investigate which degree of GHG emitted to produce the species (swimming crab and snow crab) from various fisheries. Here, we calculated the GHG emission to produce the species from the fisheries using the life cycle assessment (LCA) method. The system boundary and input parameters for each process level are defined for LCA analysis. The fuel use coefficients of the fisheries for the species are also calculated according to the fuel type. The GHG emissions from sea activities by the fisheries will be dealt with. Furthermore, the GHG emissions for producing the unit weight species and annual production are calculated by fishery classification. The results will be helpful to establish the carbon footprint of seafood in Korea.

본 연구는 동백나무 종자에 함유된 생리활성물질인 camelliaside B의 표준정량화를 위해 고성능 액체 크로마토그래피 (HPLC-DAD) 분석법을 확립하고자 실시하였다. 동백나무 종자에 함유된 주요화합물은 MS/MS 분석, UV 흡광도, 화합물의 유지시간 등을 통해 얻은 결과에 바탕을 두어 camelliaside B를 동백나무 종자 추출물의 지표물질로 선정하였다. Camelliaside B의 HPLC 분석법에 대한 특이성, 정확성, 정밀도 및 정량한계 등을 검증하였다. Camelliaside B 분석을 위해 표준화된 HPLC 분석법은 0.99% 이상의 상관계수(R2)로 높은 선형성을 가지는 것을 보여주었다. Camelliaside B의 회수율은 100.42-108.00%였으며, 검출한계 (LOD)와 정량한계 (LOQ)는 각각 0.084㎍/㎖, 0.254㎍/㎖였다. 동백나 무 종자 지표물질 (camelliaside B)의 일중 정밀도는 각각 0.09-0.16 RSD였으며, 일간정밀도는 0.123 RSD였다. 표준화된 분석법으로 지역별로 수집한 동백나무 종자의 camelliaside B의 함량은 0.279-2.05㎎/g 으로 다양하였다. HPLC 분석법으로 확인한 모든 매개변수는 기능성 원료 인정을 위한 제출자료 작성 기준을 충족하였다. 따라서 본 연구에서 확립한 HPLC 분석법은 동백나무 종자 추출물 유래 건강 관련 기능성 제품 또는 의약품 개발의 첫 단계를 제공할 수 있을 것이다.

Neptunium (Np) is one of the daughter elements included in the decay chain of Pu. The quantitative analysis of Np isotopes is required for radioactive waste characterization, research on actinide chemistry, etc. Np-237 has a long half-life (2.144 million years), but its daughter Pa-233 has a relatively short half-life (26.975 days). For this reason, after a sufficient time elapses following the chemical preparation process of the analyte, the two nuclides are in radiation equilibrium in the sample. Np-237 emits alpha-rays while Pa-233 emits beta-rays. Both nuclides also emit gamma- and X-rays. In this study, alpha-rays were measured using liquid scintillation counting (LSC) method and alpha spectrometry. Gamma-spectrometry with a HPGe detector was used for the analysis of gammaand X-rays. In addition, we compared the radiometric results with quantitative analysis of Np using UV-Vis absorption spectrometry. The LSC method and the HPGe gamma-spectroscopy do not require extensive sample preparation procedures. Alpha spectroscopy requires a standard material spiking, separation by coprecipitation, and disk-type sample preparation procedure to obtain measurement efficiency and recovery factor. A reference material sample with a concentration of 5.8 mM was analyzed by the four analysis methods, and all of the measured results agreed well within a difference level of 4%.

During electrorefining, fission products, such as Sr and Cs, accumulate in a eutectic LiCl-KCl molten salt and degrade the efficiency of the separation process by generating high heat and decreasing uranium capture. Thus, the removal of the fission products from the molten salt bath is essential for reusing the bath, thereby reducing the additional nuclear waste. While many studies focus on techniques for selective separation of fission products, there are few studies on processing monitoring of those techniques. In-situ monitoring can be used to evaluate separation techniques and determine the integrity of the bath. In this study, laser-induced breakdown spectroscopy (LIBS) was selected as the monitoring technique to measure concentrations of Sr and Cs in 550°C LiCl-KCl molten salt. A laser spectroscopic setup for analyzing high-temperature molten salts in an inert atmosphere was established by coupling an optical path with a glove box. An air blower was installed between the sample and lenses to avoid liquid splashes on surrounding optical products caused by laser-liquid interaction. Before LIBS measurements, experimental parameters such as laser pulse energy, delay time, and gate width were optimized for each element to get the highest signal-to-noise ratio of characteristic elemental peaks. LIBS spectra were recorded with the optimized conditions from LiCl-KCl samples, including individual elements in a wide concentration range. Then, the limit of detections (LODs) for Sr and Cs were calculated using calibration curves, which have high linearity with low errors. In addition to the univariate analysis, partial least-squares regression (PLSR) was employed on the data plots to obtain calibration models for better quantitative analysis. The developed models show high performances with the regression coefficient R2 close to one and root-mean-square error close to zero. After the individual element analysis, the same process was performed on samples where Sr and Cs were dissolved in molten salt simultaneously. The results also show low-ppm LODs and an excellent fitted regression model. This study illustrates the feasibility of applying LIBS to process monitoring in pyroprocessing to minimize nuclear waste. Furthermore, this high-sensitive spectroscopic system is expected to be used for coolant monitoring in advanced reactors such as molten salt reactors.

This study evaluated the sensory characteristics of sauerkraut prepared by adding 0.5, 1.0, 1.5, 2.0, and 2.5% (w/w) sea salt to cabbage. The quantitative descriptive analysis (QDA) and acceptance test of sauerkraut were determined for each salt concentration, and the principal component analysis (PCA) and partial least square regression (PLSR) analysis were performed to confirm the correlation between each factor. Results of the QDA determined 14 descriptive terms; furthermore, brightness and yellowness of appearance and the sour, salty, and bitter flavors differed significantly according to the salt concentration. Results from the PCA explained 22.56% PC1 and 65.34% PC2 of the total variation obtained. Sauerkraut prepared using 0.5, 1.0, and 1.5% sea salt had high brightness, moistness, sour odor, green odor, sour flavor, carbonation, hardness, chewiness, and crispness, whereas sauerkraut prepared with 2.0 and 2.5% sea salt had high yellowness, glossiness, salty flavor, sweet flavor, and bitter flavor. Hierarchical cluster analysis classified the products into two clusters: sauerkraut of 0.5, 1.0, and 1.5%, and sauerkraut of 2.0 and 2.5%. Results of PLSR determined that sauerkraut of 1.0 and 1.5% were the closest to texture, taste, and overall acceptance. We, therefore, conclude that sauerkrauts prepared using 1.0 and 1.5% sea salt have excellent characteristics in appearance, taste, and texture.

Safety evaluation of high-level radioactive waste disposal facilities including spent nuclear fuel is a very urgent and critical issue, and in order to do so, it is very important to develop a safety case that includes Feature, Event, Process (FEP) analysis, scenario development, and scenario uncertainty evaluation. In the case of Korea, the disposal of spent nuclear fuel is recognized as an unavoidable option, and in the end, Korea’s specific FEP (SFEP) development and safety evaluation according to the scenario should be conducted. Because each country’s situation and environment are different, it is necessary to develop an SFEP based on a generic FEP (International FEP). To this end, an understanding of IFEP is essential. In this study, about 1,000 major terms appearing in the OECD/NEA IFEP are classified to where each of them belongs among F, E, and P, and which FEP each word belongs to, and the correlation between the frequency of occurrence and each term is analyzed. This result will serve as a reference for the results of SFEP analysis such as POSIVA and SKB, which our research team will analyze later. In addition, each term belongs to which academic field, and the most appropriate translation for translating each term into Korean is also described.

Mercury and its compounds are globally managed chemicals as risks to the human body and ecosystem. It mainly enters the human body through ingestion of seafood, especially, methylmercury causes serious diseases such as central nervous system (CNS) disorder and renal dysfunction. In this study, total mercury (Hg) and methyl mercury (MeHg) were determined in seafood (16 species, n = 97) commonly consumed in Daejeon, using a gold amalgamation method. The average concentration (Hg/MeHg mean ± S.D. (minimum–maximun) mg/kg) of total Hg and MeHg in the samples was as follows; Fish 0.038 ± 0.058 (0.004 – 0.272) / 0.028 ± 0.047 (N.D. – 0.236), Crustacea 0.023 ± 0.021 (0.003 – 0.078) / 0.016 ± 0.018 (N.D. – 0.055), Mollusks 0.015 ± 0.015 (0.002 – 0.056) / 0.008 ± 0.013 (N.D. – 0.040). The concentration of MeHg in seafood were significantly correlated with total Hg concentration (p<0.001). The species with the highest average concentration of Hg was the Korean rockfish, but there was no sample that exceeded the maximum residual limit. The total %provisional tolerable weekly intake (%PTWI) value of MeHg for all of the samples was 3.76%, compared with the JECFA’s reference value, which indicates that there is almost no health risk from heavy MeHg intake through the consumption of seafood distributed in Daejeon.

This study is a follow-up of Lee (2018) providing a quantitative variationist analysis on the variation of English loanword expressions for ‘smartphone application’ in Korean: ayp, ephul, ayphullikheyisyen, and ephullikheyisyen. Two different data sets including search term frequency ratio from Naver Data Lab and sociolinguistic survey responses from 335 participants regarding the usage of the four loanword variants were examined to identify the usage pattern of the lexical variable. Both search term frequency data and survey responses confirmed that the usage of clipped variants, ayp and ephul, were clearly preferred to their full-formed variants. Logistic regression analyses on the survey data reported that survey takers with higher educational background and more experience in English speaking countries favored using ayp and ayphullikheyisyen. This study argues that Korean speakers with higher education background and more exposure to English favored ay- variants because they considered those variants as more appropriately generated loanwords than evariants.

A wire rod, a material for multistage cold forging, is subjected to spheroidization and low annealing heat treatment to secure formability, and a phosphate coating treatment on the material surface to secure lubricity. The film layer produced by the phosphate treatment process is involved in adhesion to the material surface, adhesion to the forging die surface, and lubricity. This results in the increase or decrease of the forming load and the increase or decrease of the die life in the cold forging process. In particular, as the cold forging process progresses, the phosphate film is damaged and the original performance is deteriorated, so there is a high possibility of process defects. In case of excessive damage, the film is completely lost and die soldering occurs. Therefore, in this study, quantitative criteria for phosphate film damage are presented and the effect on the cold forging process is analyzed based on this to improve process analysis prediction accuracy. Therefore, in this study, quantitative criteria for phosphate film damage are presented, and based on this, the friction coefficient in the multi-stage cold forging process is to be derived.