In a previous study, beverages containing Centella asiatica extracts (CAE) that exhibited anti-inflammatory effects were prepared. This study aimed to establish the optimal extraction conditions for CAE to enhance its anti-inflammatory activity in functional labeling beverages (FLB-CCS) containing Aloe vera gel powder and Codonopsis lanceolata extract, and to determine their effects on intestinal epithelial cells. Initially, FLB-CCS 1 (containing 3% CAE) and FLB-CCS 2 (containing 1% CAE), which had varying CAE extraction ratios, displayed no significant cytotoxicity in IL-1β-induced inflammatory intestinal epithelial (Caco-2) cells. FLB-CCS 1 significantly more effectively inhibited the production of inflammatory factors, such as IL-6 and monocyte chemoattractant protein-1 (MCP-1), compared to FLB-CCS 2. FLB-CCS 1 also reduced the mRNA expression of genes encoding IL-6 and MCP-1. Additionally, FLB-CCS 1 regulated the expression of IL-1 receptor type 1 by inhibiting the nuclear translocation of the NF-κB transcription factor p65. In conclusion, these results suggest that an increased CAE extraction ratio (FLB-CCS 1) could enhance the anti-inflammatory activity and serve as materials in functional labeling beverages for intestinal health.

In this study, Pleurotus ostreatus were grown in bottles at temperatures set to 15°C, 20°C, and 25°C inside the cultivation room. Changes in temperature, CO2 concentration, and humidity inside the bottles were measured, and growth characteristics according to the temperature conditions were evaluated. CO2 concentration increased overall as the temperature increased and was particularly stable at 20°C, suggesting that 20°C is the optimal condition for the physiological respiration of P. ostreatus . While humidity was relatively constant at 15°C, it decreased over time at 20°C and was maintained at a stable level at 25°C, suggesting that water retention capacity may occur at high temperatures. As a result of the growth investigation, the yield per bottle and individual weight were the highest at 20°C, confirming that 20°C is the most suitable temperature condition for the growth of oyster mushrooms. At 25°C, the yield per bottle was maintained but the individual weight decreased and the color tended to change. These results suggest that the interaction between CO2 concentration, humidity, and temperature has a significant effect on the growth and quality of oyster mushrooms, and that it is effective to control the cultivation room temperature to 20°C for optimal growth.

This review examines the importance of measuring practical enteric methane emissions from ruminants, considering their significant impact on global warming. Global warming is significantly driven by an increase in greenhouse gases, with rising methane (CH4) emissions from ruminants accelerating global warming recently. To successfully mitigate CH4 emissions and establish effective strategies, it is essential to apply reliable measurement techniques. This will allow for an accurate assessment of on-farm CH4 emissions. The priority should be to gather CH4 emission data that reflects the actual state of CH4 emissions from ruminants. The review provides an overview of the methods used to measure CH4 emissions from ruminants by compiling existing researches. It introduces the concepts, principles, and limitations of these methods to facilitate comparisons between existing approaches. This review discusses methods for measuring enteric CH4 emissions from ruminants at the farm level, including the tracer technique, laser methane detector, GreenFeed, and sniffer system. These methods are highlighted as potential tools to accumulate substantial data on on-farm CH4 emission from domestic animals with provides examples of international cases. Among these, this review introduces the Sniffer method, a CH4 emission measurement techniques that are suitable for on-farm use under domestic conditions, and emphasizes the necessity of its application. In addition, by presenting international cases where predictive models were developed based on on-farm CH4 measurement techniques, it is projected that if predictive models for CH4 emissions are developed by accumulating data at the farm level, it can contribute to sustainable livestock industry in various promising ways.

This study was conducted to secure basic data for developing technologies to reduce the generation of odor substances by investigating the effects of environmental temperature on growth performance and the generation of odor substances from feces in growing pigs. A total of 16 pigs (Landrace × Yorkshire × Duroc, average body weight 56.49±0.47kg) were randomly assigned to two treatments: thermal-neutral (TN) and heat stress (HS) conditions. The experiments were conducted for two weeks, with average temperature-humidity indices of 68.91±0.09 for TN and 85.98±0.08 for HS. The results showed that HS significantly decreased average daily feed intake (ADFI, 33.3%) and average daily gain (ADG, 25.8%) compared with TN (p<0.05). Non-esterified fatty acid in serum was lower (36.2%) in HS compared with TN (p<0.05). However, protein, blood urea nitrogen, cholesterol, triglyceride, glucose, and IgG in serum showed no difference between HS and TN. Phenol (350.0%) and skatole (416.3%) were significantly higher in HS than in TN (p<0.05). The decrease in growth performance is attributed to reduction in ADFI. The increase in phenol and skatole in HS is presumed to be due to the effect of HS on the metabolism of intestinal microbial composition. Digestion rate, intestinal microbial composition, and urine emissions are known to affect odor substances. Further research on the content of odor substances in urine, nutrient digestion rate, and intestinal microbial composition is considered necessary to determine the exact associations.

This study explored the suitability of nurungji as a substitute for malt. Rice beers (R20, R40, R60) and nurungji beers (N20, N40, N60) were prepared by substituting 20%, 40%, and 60% malt with the rice and nurungji, respectively. All samples were fermented at 25oC for 5 days and stored at 2oC for 15 days to study quality characteristics. The pH value of wort solution was the highest at R60. The viable cell counts of all samples were not significantly different during fermentation and storage. As the amount of rice and nurungji increased, the L value in chromaticity increased, whereas the a and b values tended to decrease during fermentation and storage. The reducing sugar, soluble solid contents, and specific gravity of the wort solution were higher in nurungji beer than in rice beer. After fermentation and storage, the alcohol content of N40 was 5.83%, the highest among the prepared rice and nurungji beers. The total polyphenol, flavonoid contents, DPPH, and ABTS scavenging activity of beer decreased with increased rice and nurungji substitution ratios during fermentation and storage. Notably, nurungji beer showed higher antioxidant activity than rice beer during fermentation and storage.

본 연구는 정향, 황련 추출물을 혼합하여 Malassezia furfur에 대한 항균 능력을 확인하고 최 적의 혼합물을 만들어 항산화 및 항염증 능력을 평가하기 위해 수행되었다. 정향과 황련을 70% 에탄올, 100% 메탄올, 열수로 추출하여 항균 능력을 평가하여 정향은 100% 메탄올 추출물, 황련은 열수 추출 물이 가장 항균 능력이 높은 것을 확인하였다. 또한 두 추출물을 혼합하여 비율별로 항균 능력을 평가 하였을 때 9:1 비율이 가장 우수한 활성을 보였고 혼합물의 항산화 활성이 뛰어남을 확인하였다. Raw 264.7 세포에서 생존율에 영향을 미치지 않는 1, 10, 50, 100 μg/mL에서 LPS를 이용하여 염증 반응을 유도하고 항염증 활성을 확인한 결과 10, 50, 100 μg/mL에서 No 생성 저해율과 IL-6 발현 저해율 및 COX2, iNOS 단백질 발현 저해 활성이 뛰어남을 확인하였다. 본 연구를 통해 정향 메탄올 추출물 및 황련 열수 추출물의 혼합물은 항균, 항염증 효능이 뛰어나기에 기능성 화장품의 천연 소재로써 사용이 가능할 것으로 사료된다.

The aim of this study was to investigate the hypoglycemic effects of saengshik in Sprague-Dawley (SD) rats and to explore the potential of three commercially available saengshik products (BS, LS, WS) as an alternative diabetic meal. Blood glucose levels were measured at 30, 60, 90, 120, and 150 minutes after the ingestion of experimental materials. In experiment 1, the amount of experimental materials remained the same. We measured blood glucose-related biomarkers as the area under the blood glucose response curve (AUC), glycemic index (GI), maximum concentration (Cmax), and time to reach maximum concentration (Tmax). AUC and Cmax of the experimental group showed significant differences compared to the control group, while GI and Tmax did not show significant differences among the groups but were lower in the experimental group compared to the control group. In experiment 2, carbohydrates were adjusted to the same amount. We measured blood glucose-related biomarkers in the same manner as Experiment 1 and obtained similar results. These hypoglycemic effects appear to be attributed to phytochemicals and dietary fiber found in whole, unrefined grains. These results suggest that saengshik exerts hypoglycemic effects by modulation of glucose-related biomarkers.

In this study, changes in the microstructure and mechanical properties of cast and extruded Al-2Li-1Ce alloy materials were investigated as the Mg content was varied. The density decreased to 2.485, 2.46 and 2.435 g/cm3 when the Mg content in the Al-2Li-1Ce alloy was increased to 2, 4 and 6 wt%, respectively. Intermetallic compounds of Al11Ce3 were observed in all alloys, while the β-phase of Al3Mg2 was observed in alloys containing 6 wt% of Mg. In the extruded material, with increasing Mg content the average grain size decreased to 84.8, 71.6 and 36.2 μm, and the fraction of high-angle grain boundaries (greater than 15°) increased to 82.8 %, 88.6 %, and 91.8 %, respectively. This occurred because the increased Mg content promotes dynamic recrystallization during hot extrusion. Tensile test results showed that as the Mg content increased, both the yield strength and tensile strength increased. The yield strength reached 86.1, 107.3, and 186.4 MPa, and the tensile strength reached 215.2, 285, and 360.5 MPa, respectively. However, it is worth noting that the ductility decreased to 27.78 %, 25.65 %, and 20.72 % as the Mg content increased. This reduction in ductility is attributed to the strengthening effect resulting from the increased amount of dissolved Mg, and grain refinement due to dynamic recrystallization.

효율적인 산림관리와 경영이 이루어지기 위해서는 일정한 공간단위를 가지는 산림의 구획(Zoning)이 정의되어야 한다. 현재 국유림은 임･소반 기준으로, 공･사유림은 필지 단위를 기준으로 공간을 구획하여 활용하고 있다. 이러한 이원적인 공간구획체 계는 통일된 산림계획, 경영, 관리가 어려우며 장기적인 공간단위의 정보 구축과 생성, 관리에도 어려움을 끼칠 수 있다. 이에, 본 연구에서는 DEM(Digital Elevation Model) 기반으로 추출한 산줄기 유역을 소개하고 활용성 검토를 위해 현재 산림관리 단위인 임･소반도, 경영계획구, 산지/산림 관련 주제도와 중첩 분석을 수행하였다. 이를 통해 표준산림관리단위의 대안으로 제안한 각 규모별 산림유역 단위의 공간적 적합성을 검토하고 산림관리, 산림 디지털 공간자료 구축 및 관리 등의 분야에서 산줄기 내포 유역 기반 표준산림관리단위의 활용 방안을 제안하였다.

본 논문의 목적은 주요 과학기술인력정책의 발전과정에 대한 정리와 함께 수급 패러다임 변화라는 정책 환경 속에서 바람직한 미래 정책 방향을 도출하는 데 있다. 이를 위해 먼저 이공계 기피 현상 해소를 화두로 2000년대부터 본격 추진되었던 과학기술인력정책의 전개과정을 이공계인력 지원 기본계획을 중심으로 살펴보았다. 다음으로 디지털 전환 등으로 인해 나타나는 과학기술인력 수요 변화와 인구구조 감소라는 공급충격, 즉 과학기술인재 수급 패러다임 전환의 주요 내용과 시사점을 정리하였다. 이를 바탕으로 미래 과학기술인력정책의 핵심 방향을 우수 과학기술인재 배출과 활용의 토대가 되어 인재의 지속 성장과 유입을 촉진 시키는, 사람 중심의 과학기술 연구생태계 조성으로 제언하였다.

목적 : 본 연구는 척수손상 환자 평가 및 중재에 대한 지침과 체계적 문헌고찰을 기반으로 작업치료사들을 위한 가이드라인을 개발하는 것을 목표로 한다. 연구방법 : 수용개작과 직접 개발방식을 적용하여, 핵심 질문과 가이드라인 개발 범위를 결정하고, 가이드 라인 검색을 수행하며, 선정된 가이드라인을 평가하고 권고를 선택한다. 해결되지 않은 임상 질문에 대 한 추가적인 권고사항을 개발하고, 가이드라인 초안을 완성하고, 전문가 그룹에 의한 평가를 수행하며, 최종 가이드라인을 완성한다. 결과 : 개발된 가이드라인은 평가영역에서 17개 항목, 중재영역에서 58개 항목으로 총 75가지 항목으로 구성되었다. 각 항목은 권고 강도(A~D)에 따라 평가되었으며, 권고 강도가 높게 나타난 항목은 35개이 다. 신체기능개선중재, 욕창관리중재, 상지보호 전략, 일상생활활동 등에서 권고 강도가 높게 나타났다. 결론 : 개발된 가이드라인은 작업치료사들에게 근거기반 치료적 접근과 직무 역할의 확립을 돕는 중요한 도구로서 활용될 수 있기를 기대한다.