본 연구에서는 3D 프린팅 FDM 방식의 적층 방향에 따라 기계적 물성이 달라지는 이방성 특성을 확인하고 이를 이용하여 위상 최 적설계를 수행하였다. 벤치마크 문제인 자동차 현가장치 부품 중 하나인 로어 컨트롤 암에 대하여 밀도법 기반 위상 최적설계를 수행 하였으며, 외부 하중과 이방성 특성에 따라 위상 최적결과가 다르게 나타나는 것을 확인하였다. 이를 이용하여 최적화된 모델에 대하 여 3D 프린터로 적층 방향을 달리하여 2가지 시험품을 제작하였으며 인장시험을 수행하였다. 시험시 3D 비접촉 변형률 측정기를 이 용하여 변형률을 구하였으며 이를 CAE 응답해석으로 얻은 변형률과 비교한 결과가 정량 및 정성적으로 일치하는 것을 확인하였다. 3D 프린팅 적층 방향을 고려한 위상 최적모델의 인장 실험 결과를 통해 해당 최적설계 방법론의 유효성을 검증하였다.

Benthic macroinvertebrates are important ecological and environmental indicators as primary or secondary consumers, and therefore are widely used in the evaluation of aquatic environments. However, there are no comprehensive river ecosystem monitoring surveys that link the major physicochemical water quality items with benthic macroinvertebrates in urban streams. Therefore, this study investigated the distribution characteristics of benthic macroinvertebrates and physicochemical water quality items (17 items) in Yangjaecheon and Yeouicheon from 2019 to 2020. At the same time, by applying Spearman’s rank correlation analysis and nonmetric multidimensional scaling (nMDS) analysis in the water quality data and biotic index, we tried to provide basic data for diagnosing the current status of river ecosystems in major urban rivers in Seoul. Based on the study results, a total of 39 species and 3,787 individuals were identified in Yangjaecheon, the water quality (based on BOD, TOC, and TP) of Yangjaecheon was higher than Grade Ib (good), and the BMI using benthic macroinvertebrates appeared as Grade C (normal) at all the sites. In Yeouicheon, a total of 51 species and 4,199 individuals were identified, the water quality (based on BOD, TOC, TP) was higher than Grade Ib (good) similar to Yangjaecheon, and the BMI of both Upstream and Saewon bridge was Grade B (good), while Yeoui bridge was Grade C (normal). Overall, analysis results for the distribution of benthic macroinvertebrates by a nonmetric multidimensional scaling method showed no significant difference between the two streams (p=0.1491). Also, significant environmental variables related to benthic macroinvertebrates distribution were determined as water temperature and DO. On the other hand, the results of the correlation analysis between biotic index and major water quality items confirmed that R1 and BMI could be used for on-site urban river water quality evaluation.

This study evaluated the migrant and residue tests of lead (Pb), cadmium (Cd), nickel (Ni), arsenic (As), and antimony (Sb) in 70 tumbler samples. The migration levels of hazardous metals in all the samples were within the migration limits outlined in the Korean standards and specifications for utensils, containers, and packages. Moreover, in all the tumbler samples, only Ni was detected in 0.5% citric acid solution of a food stimulant. The maximum level of Ni 0.0144 mg/L was 14.4% of the migrant specification (not more than 0.1 mg/L), which was relatively safe. The 0.5% citric acid solution was eluted at 4oC, 70oC, and 100oC for 30 min, and only Ni was detected while testing for migration levels according to the temperature variations; all temperature conditions conformed to the standards. The level of Ni migration increased significantly with increasing migration temperature. Regarding the residue level outside the paint-coated tumbler samples, the Pb level was found to range from N.D. to 20638.1323 mg/kg. The risk of Ni was further estimated to be at a safe level of 0.00 to 0.01% compared to the %TDI as a result.

본 연구는 딸기재배시 전용 고설베드를 사용하지 않고, 일 반 수경재배 시설을 이용하여 코이어 배지를 베드에 올려 재 배하는 방법을 구명하기 위해서 실시하였다. 토마토나 파프 리카를 재배하는 시설재배 베드에 코이어의 칩과 더스트 비율 이 5:5인 코이어 배지 1겹 처리(높이 10cm; A), 2겹으로 쌓은 처리(높이 20cm; B), 코이어의 칩과 더스트 비율이 7:3인 코 이어 배지 1겹 처리(높이 15cm; C)와 대조구로는 딸기 전용 플라스틱 화분(Control) 처리구로 하였다. 생육특성은 코이 어 배지 높이별로는 유의성이 없었고, 플라스틱 화분에서 재 배한 것이 작은 경향을 보였다. 딸기 잎의 광합성율은 처리별 로 14.68－15.76μmol CO2·m-2·s-1로 통계적인 유의성은 없 었고, 뿌리의 근활력은 배지 용량이 컸던 C와 B 처리구가 A 처리구와 대조구보다는 높은 것으로 나타났다. 과장과 과폭 은 각각 4.04－4.13cm와 3.26－3.34cm로 통계적인 유의성 이 없었고, 과장과 과폭 비율은 대조구가 1.27로 A－C 처리 구의 1.23－1.24보다 뾰쪽한 형태이었다. 딸기 1주당 수확과 수는 C 처리구가 4.4개로 가장 적었고, 대조구, A, B 처리구의 6.2－6.5개로 처리간 유의성은 없었다. 상품수량 과수는 A 처 리구가 74개로 가장 많았고, C 처리구가 53개로 가장 적었으 며, 1주당 수량은 A 처리구가 72.38g으로 가장 컸고, C 처리 구가 48.69g으로 가장 작았다. 이와 같은 결과는 딸기재배 시 전용재배 시설을 설치하지 않고, 기존의 토마토나 파프리카 수경재배 시설에서 코이어 배지를 활용하여 딸기재배를 할 수 있다는 것을 나타낸다. 다만 C 처리구에서 수량이 감소한 것 은 칩과 더스트 비율이 7:3으로, A와 B 처리구의 칩과 더스트 비율이 5:5와 다른 것이 원인으로 추정되며 칩과 더스트 비율 에 따른 추가 연구가 필요하다.

본 연구는 권취식 측창을 갖는 아치형 단동 플라스틱 온실 내 강제환기장치 설치 및 운용, 환기 성능 개선방안 등을 제안 하기 위해 온실 내부에 유동팬과 배기팬을 설치하여 강제환기 장치 사용에 따른 온실 내부기온 강하 특성을 정량적으로 조 사하였다. 시험은 3가지 환기 조건(측창, 측창+순환팬, 측창+ 순환팬+배기팬)에서 수행되었다. 각 조건 데이터로거를 이용 하여 환기 시작과 동시에 온실 내외부 기온 및 외부환경 변화 를 측정·기록하였고, 환기 방식별 기온차 변화의 평균값으로 부터 정규기온차를 계산하여 기온 강하 효과를 비교하였다. 오전(11:00－12:00)에는 환기 방식에 상관없이 환기 초반 정 규기온차가 일시적으로 증가했다가 감소하는 것으로 나타났 다. 강제환기장치가 더 많이 사용될수록 최대 정규기온차는 1.158에서 1.037로 감소하였고 최대 정규기온차에 도달하는 시간도 340초에서 110초로 단축되었다. 강제환기장치의 사 용은 정규기온차가 0.8까지 감소하는데 소요된 시간을 1,030 초에서 550초로, 0.6까지는 1,610초에서 915초로, 0.4까지는 2,315초에서 1,360초로, 자연환기의 약 60% 수준으로 감소 시켰다. 오후(14:00－15:00)에는 정규기온차의 증가가 관측되지 않았지만, 환기 시작과 동시에 기온차가 감소하기 시작 했다. 또한 강제환기장치가 더 많이 사용될수록 정규기온차 가 0.8까지 내려가는 시간을 560초에서 345초로, 0.6까지는 825초에서 540초로, 0.4까지는 560초에서 345초로, 약 70% 수준으로 감소시켰다. 따라서, 보다 효과적이고 경제적인 환 기를 위해 강제환기장치는 오전과 같이 열부하가 높은 환경에 서 적극적으로 사용하는 것이 바람직하다고 판단된다.

This study was to investigate an analytical method for determining dieckol content in Ecklonia stolonifera extract. According to the guidelines of International Conference on Harmonization. Method validation was performed by measuring the specificity, linearity, precision, accuracy, limit of detection (LOD), and limit of quantification (LOQ) of dieckol using high-performance liquid chromatography–photodiode array. The results showed that the correlation coefficient of calibration curve (R2) for dieckol was 0.9997. The LOD and LOQ for dieckol were 0.18 and 0.56 μg/mL, respectively. The intra- and inter-day precision values of dieckol were approximately 1.58-4.39% and 1.37-4.64%, respectively. Moreover, intra- and inter-day accuracies of dieckol were approximately 96.91- 102.33% and 98.41-105.71%, respectively. Thus, we successfully validated the analytical method for estimating dieckol content in E. stolonifera extract.

Tomato (Solanum lycopersicum) is one of the most popular horticultural crops cultivated globally. Since the 1950s, the National Institute of Horticultural and Herbal Science (NIHHS) of Rural Development Administration (RDA) has been conducting research on developing Korean tomato cultivars. Recently, the objectives of breeding have been diversified according to the rapidly changing market trends. To meet such demands, various cultivars with distinct characteristics have been made: rootstock tomato, ornamental tomato, sweet cherry tomato, and virus resistant tomato. In 2022, a total of 20 cultivars were registered for variety protection in the Korea Seed and Variety Service (KSVS) and two cultivars with high temperature tolerance have been under field trials for application. In this paper, the breeding history and major characteristics of eight representative tomato cultivars are discussed. Since each tomato has its own valuable feature, they are expected to be used in diverse places from garden to farm.

In this study, a two-stage electrostatic precipitator (ESP) was developed using a novel automatic dry cleaning device to reduce the ultrafine particles in subway stations. Collection efficiency was evaluated with a pilot scale ESP (1.2m× 1.2m) and the scale of the test duct was half of the subway air handling unit. The maximum collection efficiency for 0.3 μm particles was 96.9%. In addition, we studied a method of automatic dry cleaning for maintenance of the ESP. The cleaning efficiency was analyzed according to the cleaning flow rate for each particle loading amount to achieve a recovery rate over 90%. In addition, we derived the equation to estimate the reduction in collection efficiency according to the particle loading amount. It was confirmed that the performance of the contaminated ESP was restored to the initial state by the automatic dry cleaning in this study and that the electrical energy consumption was 5 times lower compared to utilizing conventional water cleaning.

Background/Aim: In gallbladder cancer (GBC), gender differences in incidence and mortality rates have been reported with geographic variation. However, there is little known about sex-related difference in GBC prognosis. This study compares prognostic factors according to gender for GBC. Methods: We searched clinicopathological factors in all stages of 952 GBC patients from seven medical centers in Korea. A total of 927 patients were enrolled and surgery with curative resection was performed in 499 patients. Results: Carbohydrate antigen (≥37 U/mL) was a significant prognostic factor in both females and males (odd ratio [OR], 4.30; 95% confidence interval [CI], 3.13-5.89; p<0.001). Age was a significant factor only in female patients, elderly patients were associated with low resectability and the likelihood of T-stage >2; an independent predictor of poor prognosis via multivariate analysis (OR, 1.03; 95% CI, 1.01-1.05; p=0.005, OR, 1.05; 95% CI, 1.02-1.08; p=0.002). Body mass index (BMI) also showed gender difference, and lower BMI (≤25 kg/m2) was the significant good indicator of multivariate analysis for lymph node metastasis in female patients (OR, 0.42; 95% CI, 0.23-0.77; p=0.005) but, the significant poor indicator of univariate analysis for advanced T-stage in male (OR, 2.79; 95% CI, 1.40-5.54; p=0.003). Conclusions: These results suggest that there is a possibility of gender difference in GBC prognosis. Age and high BMI were poor prognostic factors for curative resection for female GBC patients.

This study installed and evaluated the efficiency of a radon barrier membrane, radon mat, and radon well in the removal and reduction of radon gas that originates from the soil and flows indoors. The study aims to present a fundamental and long-term solution to radon reduction in buildings by preventing soil radon, which is the main source of radon gas, from migrating indoors. A radon barrier membrane, radon mat, and radon well were developed and verified, and the radon reduction effect of each system was evaluated. Through applying a special radon gas blocking film with a 5-layer structure, the radon barrier membrane prevents radon gas particles from passing through the polymer deposited on the radon blocking film. The radon mat is a type of radon reduction construction method that induces radon gas generated from the soil under the building to move in the desired direction through the plate-structured pressure reducing panel and discharges radon gas to the outside of the building through an exhaust pipe and fan installed at the edge. In addition, the radon well can also be applied to special structures such as old buildings and historical sites where it is difficult to directly reduce radon concentration within the building foundation, because the intake area can be controlled and, therefore, the method can be applied in a variety of environments and ranges. In the case of Intervention 1 (installing a radon barrier membrane and radon mat), the soil radon was reduced by 24.7%. Intervention 2 (installing a radon barrier membrane, radon mat, and radon well) reduced the soil radon by 45.1%, indicating that the effect of reducing the soil radon concentration was 1.8 times higher compared with installing only the radon barrier membrane and radon mat. The measurement showed that the indoor radon concentration was reduced by 46.5%, following the reduction in soil radon concentration through Interventions 1 and 2, demonstrating the effect of reducing indoor radon gas by installing the radon barrier membrane, radon mat, and radon well. Through the production and installation of prototype systems, this study confirmed the reduction effect of radon concentration in soil and indoor air. These systems achieved a higher efficiency at a relatively low cost than that achieved with the existing radon reduction methods applied in Korea and abroad.

Arsenic (As) uptake and accumulation from agricultural soil to rice vary depending on the soil environmental conditions such as soil pH, redox potential, clay content, and organic matter (OM) content. Therefore, these factors are important in predicting changes in the uptake and accumulation of As in rice plants. Here, we studied the chemical properties of As-contaminated and/or rice straw compost (RSC)-treated soils, the growth responses of RSC-applied rice plants under As-contaminated soils, the changes in As content of soil, and the relationship between As uptake and accumulation from the RSC-treated soils to the rice organs under As-contaminated soils. Rice plants were cultivated in 30 mg kg-1 As-contaminated soils under three RSC treatments: 0 (control), 12, and 24 Mg ha-1. No significant differences were indicated in the chemical properties of pre-experimental (before transplanting rice seedling) soils, with the exception of EC, OM, and available P2O5. As the treatment of RSC under 30 mg kg-1 As-contaminated soils increased, EC, OM, and available P2O5 increased proportionally in soil. Increased soil RSC under As-contaminated soils increased shoot dry weight of rice plants at harvesting stage. As content in roots increased proportionally with RSC content, whereas As content in shoots decreased under As-contaminated soil at all stages of rice plants. Nevertheless, As accumulation were significantly decreased in both roots and shoots of RSC-treated rice plants than those in the plants treated without RSC. These results indicate that the use of RSC can mitigate As phytotoxicity and reduce As accumulation in rice plants under As-contaminated soils. Therefore, RSC can potentially be applied to As-contaminated soil for safe crop and forage rice production.

지중관수에 의한 밭작물의 농업용수는 30%이상 절감되고 가용용수량도 지표면 관수에 비해 2배 이상의 효과가 있는 것으로 알려져 있다. 이것은 수분을 지중에 공급하므로 증발산으로 인한 손실을 줄일 뿐만 아니라 지중의 확산 체적을 넓혀 지표면에 비해 수분공급 효과를 높일 수 있기 때문이다. 뿐만 아니라 관수 노동력도 절감되므로 최근 지중관수 장치의 보급이 확산되고 있는 추세이다. 그러나 우리나라는 아직까지 지중관수 장치가 개발되지 않아 농민들은 수입품 자재에 의존하고 있는 실정이다. 지중관수 장치는 3가지 중요한 기능을 가지고 있다. 첫 번째는 공급압력 100-400 kPa 사이에 유량 오차가 5-10% 범위에서 균등해야 하고, 두 번째는 토양속에서 수분을 공급하므로 뿌리가 토출구 속으로 들어가 내부의 관수구가 막히지 않아야 한다. 세 번째는 용수 공급을 중단했을 때, 관수구에서 누수가 되지 않도록 설계⋅제작되어야 한다. 또한 지중에 수분을 공급하므로 지표면 관수와 달리 이상 유무에 대해 확인하기 어려운 점이 있기 때문에 장치의 신뢰성이 높아야 한다. 따라서 지중관수 장치의 핵심은 3가지 기능을 가진 드리퍼의 개발이 우선되어야 가능하다. 유량의 균등성을 유지하는 것은 드리퍼 내부에 압력보상 기술(pressure compensation technology)에 의해 좌우된다. 드리퍼는 outer, lower insert 및 upper insert의 구성요소로 이루어져 있고, 내부에 압력조정 기능 즉, 밸브의 역할을 하는 실리콘이 내장되어 있다. 드리퍼가 유량 균등성, 뿌리 막힘 및 역류방지 기능을 수행하기 위해서 약 10가지의 설계변수를 고려해야 한다. 특히 드리퍼에서 유량이 가장 먼저 통과하는 outer의 원추 높이와 실리콘 경도는 유량 균등성에 미치는 영향이 가장 클 뿐만 아니라 공급유량의 중지 시에는 역류방지의 기능도 동시에 하게 된다. 본 연구에서 개발된 지중관수용 드리퍼의 유량 균등성은 95%를 목표로 하였다. 또한 국내서 개발한 4종의 개발품과 2종의 해외 제품을 대상으로 뿌리 침투 장면도 확인하였고, 역류 방지기능에 대해서는 관수중단점 압력 29 kPa에서 관수가 중단되는 것으로 나타나 성능이 우수한 것으로 판단되었다.

A field study was conducted to reduce airborne bacteria by supplying active ions to indoor spaces used by vulnerable human groups spending substantial amounts of time in places such as schools and hospitals. In an experiment conducted during school hours (8:00-15:00), the average number of airborne bacteria in classrooms was 345.53 CFU/m3 or more without active ions. However, ion supply reduced the airborne bacteria to an average of 113.23 CFU/m3, indicating an efficiency of 61.61%. As a result of tests in 33 rooms used for surgery in small and middle sized hospitals, ion supply for 2 to 4 hours reduced the average airborne bacteria concentration from 243.88 CFU/m3 to 104.34 CFU/m3, representing a 41.53% reduction. A laboratory test to confirm the ion activity has shown that the mortality rate of E. coli used as a test bacterium increased with exposure time to ions. The initial colony number of E. coli was 251 CFU, but decreased to 4 CFU after 60 minutes of exposure to active ions. Therefore, it was confirmed that the supply of active ions can contribute to the control of airborne bacteria in the indoor environment of schools, hospitals and other public facilities.

Seoul has installed mechanical air filters in the heating, ventilation, and air conditioning (HVAC) systems of city buses to improve their indoor air quality since late 2019. We evaluated particle removal efficiencies of the filter in a wind tunnel, and clean air delivery rates (CADRs) of the systems and a household air purifier in the buses, following the test standards. The filter showed the efficiencies of 91% and 97.6%, 88% and 97.9%, and 78% and 95.2% for 0.35 μm particles and PM2.5 at 1.0m/s, 1.5m/s, and 2.0m/s, respectively. The efficiencies rose with an increase in the particle size and the filters had a minimum efficiency reporting value (MERV) rating of 15. The CADRs for PM2.5 and flow rate of the systems were 12.7m3/min and 17.9m3/min, 16.6m3/min and 25.4m3/min, 18.7m3/min and 33.6m3/min, and 23.3m3/min and 47.1m3/min on the operation mode of 1, 2, 3, and 4, respectively. The CADRs of the systems were 3.8-7.1 times higher than those of the air purifier, but single-pass removal efficiencies of the former were 0.56-0.81 lower than those of the latter.

본 연구는 우리나라 Jersey 암소 41두로부터 측정된 체중 데이터를 이용해 Gompertz, von Bertalanffy 및 Logistic 모형의 성장 곡선을 추정하고, 추정된 성장 곡선의 모수를 활용하여 Jersey 암소의 성장 특성에 대해 알아보고자 실시하였다. 추정된 Gompertz, von Bertalanffy 및 Logistic 모형의 성장 곡선 함수식은 각각    ,         및          이었다. Gompertz, von Bertalanffy 및 Logistic 모형에 대해 변곡점은 각각 10.719, 8.4292 및 14.618 개월로 추정되었고, 변곡점 체중은 각각 208.514, 211.347 및 203.548kg으로 추정되었으며, 최대 증체율은 각각 20.851, 21.192 및 21.993 (kg/월)로 추정되었다. 오차 평균 제곱합과 모형 결정 계수의 결과를 종합해보면 von Bertalanffy, Gompertz 그리고 Logistic 모형 순으로 Jersey 암소 성장 곡선에 적합도가 높은 것으로 판단된다.

Purpose: This study aimed to explore the meaning of simulation practice after experiencing virtual simulation for nursing students with clinical practice experience. We attempted to determine a nursing simulation strategy as an alternative to the clinical practice in the COVID-19 pandemic. Methods: The participants were seven nursing students who experienced clinical practice and completed alternative virtual simulation practice in the COVID-19 pandemic. The data were collected through in-depth interviews and analysed using the phenomenological methodology. The key question was “what is the meaning and nature of child health nursing practice using virtual simulation in the COVID-19 pandemic?” Results: The significant statements were categorized into 14 themes, 7 theme clusters, and 2 categories. The categories extracted were “a sense of difference between virtual and reality” and “experience systematic learning transfer.” Conclusion: Practical education through nursing simulation is important for students to experience a systematic and efficient learning. Additionally, simulation educators should produce various efforts to help students achieve the learning outcomes, such as scenarios, class environments, and instructor preparation, to reduce their sense of separation from practice.

The present study was conducted to examine the effect of soybean silage as a crude protein supplement for corn silage in the diet of Hanwoo steers. The first experiment was conducted to evaluate the effect of replacing corn silage with soybean silage at different levels on rumen fermentation characteristics in vitro. Commercially-purchased corn silage was replaced with 0, 4, 8, or 12% of soybean silage. Half gram of the substrate was added to 50 mL of buffer and rumen fluid from Hanwoo cows, and then incubated at 39°C for 0, 3, 6, 12, 24, and 48 h. At 24 h, the pH of the control (corn silage only) was lower (p<0.05) than that of soybeansupplemented silages, and the pH numerically increased along with increasing proportions of soybean silage. Other rumen parameters, including gas production, ammonia nitrogen, and total volatile fatty acids, were variable. However, they tended to increase with increasing proportions of soybean silage. In the second experiment, 60 Hanwoo steers were allocated to one of three dietary treatments, namely, CON (concentrate with Italian ryegrass), CS (concentrate with corn silage), CS4% (concentrate with corn silage and 4% of soybean silage). Animals were offered experimental diets for 110 days during the growing period and then finished with typified beef diets that were commercially available to evaluate the effect of soybean silage on animal performance and meat quality. With the soybean silage, the weight gain and feed efficiency of the animal were more significant than those of the other treatments during the growing period (p<0.05). However, the dietary treatments had little effect on meat quality except for meat color. In conclusion, corn silage mixed with soybean silage even at a lower level provided a greater ruminal environment and animal performances, particularly with increased carcass weight and feed efficiency during growing period.

연구는 갈치 Trichiurus lepturus의 성 성숙과 생식생물학적 기초 정보를 제공하기 위해 수행하 였다. 난자형성과정 동안 난모세포와 핵의 크기는 증가하였으나 핵에 대한 인의 비율은 감소 하였다. H-E 염색 결과, 세포질의 염색성은 호염기성에서 호산성으로 변하였다. 난황형성개시 기 난모세포의 난경은 약 63.2 (±12.7) μm였다. 세포질에서는 호산성의 난황핵이 관찰되었다. 성숙기 난모세포의 난경은 216.6 (±24.7) μm였으며, GVBD (germinal vesicle breakdown)가 관 찰되었다. 완숙기 난모세포의 난경은 317.9 (±80.9) μm였으며, 방사대의 두께는 4.2 (±1.7) μm 였다. 난모세포의 발달형태는 난군동기발달형에 속하며, 난황 축적은 대부분의 경골어류와 마 찬가지로 외재적 방법과 내재적 방법에 의한 것으로 판단되었다.

본 연구는 동물교감활동 프로그램을 시행하면서 대학생과 동물 간의 유대감을 형성시 킴으로써 우울과 스트레스를 감소 시키는 것에 목적으로 두었다. 본 연구는 대학생을 대 상으로 아론 벡의 우울척도, 스트레스 인지 검사, 빗속의 사람 그림검사 방법을 사용하여 동물교감활동 프로그램을 진행한 후 우울, 스트레스의 변화에 대해서 살펴보았다. 본 연 구의 결과는 다음과 같다. 첫째, 동물교감활동이 대학생의 우울감을 낮추는 데 긍정적인 영향을 주었다. 둘째, 동물교감활동이 대학생의 스트레스를 낮추는 데 유의한 효과를 보 였다. 본 연구는 대학생을 대상으로 한 동물교감활동의 효과성을 검증함으로써 동물교감 활동의 연구에 기여한 것에 의의가 있다.

This study evaluated whether fevernill, which is primarily composed of acetaminophen, vitamin C, and anhydrous citric acid, is effective in relieving stress caused by foot-and-mouth disease virus (FMDV) vaccination in calves. Three-month-old calves from a farm in Korea were randomly assigned to one of three groups (n = 10 per group: control [untreated], group A [FMDV vaccination], and group B [FMDV vaccination + addition of fevernill 0.2% to feed for five days after vaccination]). Body weights, antibody formation, clinical symptoms, serum parameters were measured in the 14 days following vaccination. Total weight gain and average daily gain during the experiment period were group A (12.00±1.15 kg, 0.86±0.08 kg/day) compared to group B (13.57±0.98 kg, 0.97±0.07 kg/day) was significantly improved (p<0.05). There was no significant difference in the formation of antibodies against the FMDV vaccine between group A and group B, though the antibody value of group B tended to be higher than that of group A. The pre-inflammatory cytokine TNF-α value was 74.47±19.26 pg/ml in group A and 59.05±11.88 pg/ml in group B on the 5th day of the experiment, which was significantly lower in group B than in group A (p<0.05). Also, cortisol concentrations were significantly lower in group B than in group A (p<0.05). In conclusion, the feeding of fevernil is judged to be helpful in mitigating the side effects caused by FMD vaccination, and thus it is thought to be able to prevent the decrease in productivity caused by vaccination.