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Vol.35 No.4 (2025년 8월) 22건

21.
2025.08 구독 인증기관 무료, 개인회원 유료
The conversion of tannic acid into carbon dots enhances its antiviral activities
Caifeng Ren, Yanrong Zhou, Yuan Wu, Liurong Fang, Jiangong Liang, Shaobo Xiao
Carbon Letters Vol.35 No.4 pp.1795-1809 한국탄소학회
Tannic acid (TA) is one of the active components in the Galla Chinensis and has various effects, including antioxidant and anti-inflammatory properties. However, research on its antiviral properties remains limited. Here, tannic acid carbon dots (TA-CDs) were prepared as potential antiviral drugs from polyphenol TA under different temperature conditions (180, 200, 220 and 240 °C). Compared to TA alone, TA-CDs exhibited lower cytotoxicity and a tenfold enhanced in antiviral activity. Additionally, the antiviral effects of TA-CDs varied with preparation temperatures, with the best effect observed at 200 °C (CDs-2), reaching a titer of 2.8 orders of magnitude in porcine reproductive and respiratory syndrome virus (PRRSV), mainly due to its relatively higher number of functional groups and smaller particle size. Mechanically, CDs-2 was shown to inhibit PRRSV by targeting the stages of inactivation, adsorption, invasion, replication, and down-regulating reactive oxygen species (ROS) levels. Moreover, CDs-2 exhibited a high inhibitory effect on porcine epidemic diarrhea virus (PEDV), reaching a titer of 7 orders of magnitude. This study reveals the importance of temperature in synthesis of traditional Chinese medicine-derived carbon dots (TCM-CDs) and confirms their potential as antiviral drugs, providing valuable information for development of TCM antiviral drugs.
4,800원
22.
2025.08 구독 인증기관 무료, 개인회원 유료
Non‑enzymatic electrochemical sensor for the reliable determination of catechol using RuS2/ WO3/MWCNT ternary composite
Sreelekshmi, Beena Saraswathyamma
Carbon Letters Vol.35 No.4 pp.1811-1831 한국탄소학회
This work focuses on the development of an innovative detection platform utilizing a novel ternary composite of transition metal dichalcogenide ruthenium disulfide ( RuS2), tungsten trioxide ( WO3) and multi-walled carbon nanotubes ( RuS2/ WO3/MWCNT) for the purpose of detecting hazardous pollutant catechol. An augmented current response for catechol was acquired by the synergetic effect of ternary composite. The unique combination of these materials enhances the sensor’s electrochemical performance due to the excellent catalytic activity of RuS2, redox properties of WO3 and the high surface area and electrical conductivity provided by MWCNTs. Morphological and structural characterizations were done using different characterization methods. The increased electroactive surface area and fast electron transfer rate resulted by the adaptation of the working electrode leads to the development of a sensitive and selective sensor. The RuS2/ WO3/MWCNT modified electrode exhibited remarkable sensitivity towards catechol determination with a wide linear detection range of 1.0–1028.0 μM and a modest low detection limit of 0.61 μM. The sensor demonstrated consistent performance in assessing the reproducibility and repeatability trials. The fabricated sensor gave reliable results and satisfactory recovery range when application on real-time sample analysis.
5,700원
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