간행물
한국약용작물학회지 KCI 등재 Korean Journal of Medical Crop Science
- 발행기관 한국약용작물학회
- 자료유형 학술지
- 간기 격월간
- ISSN 1225-9306 (Print)2288-0186 (Online)
- 수록기간 1993 ~ 2019
- 주제분류 농수해양 > 농학 농수해양 분류의 다른 간행물
- 십진분류KDC 524DDC 633
권호리스트/논문검색
Vol. 23 No. 3 (2015년 6월) 14건
2.
2015.06
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In this study, the clinical safety and toxicology of oral ingestion of supplement capsules containing ginsengradix was investigated in healthy young volunteers. This study was a pilot randomized, double blinded, placebo controlledtrial. The healthy volunteers were divided into 6 groups of 20 each (10males and 10 females). They took the ginseng powderfor 35 days (3g/day) for safety evaluation. There were measured general healthy levels such as hematological, biochemical andelectrocardiographic parameters. After the first week, besides Korean white ginseng the other treatments led to an significantincrease of white blood cells. Korean red ginseng increased UREA (blood urea nitrogen) in healthy volunteers, but it didn’texceed the range of normal values, and in the subsequent process of treatment there is no effect of elevating UREA. After thethree weeks, Korean white ginseng showed relatively low the content of blood glucose and low-density lipoprotein cholesterol.After the five weeks, compared with the other treatments, Korean red ginseng increased white blood cells, platelet distributionwidth and average volume of platelet. Korean white ginseng decreased low-density lipoprotein cholesterol. American ginsengdecreased blood creatinine in healthy volunteers. In conclusion, through test the blood routine, urine routine, liver function,renal function, blood glucose, blood lipid and electrocardiogram, the healthy volunteers continuous taking ginsengfor 35 days (3g/day) is safe and reliable, and have no obvious adverse reactions and side effects.
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2015.06
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In this study, we tried to offer the possibility of White Hibiscus syriacus L. (WHS) flower extracts as a preven-tive and improving agent of osteoporosis that bone mass reduction is induced by an decrease of osteoblast involved in boneformation and increase of bone resorption by osteoclast activity. As a results, it was found to have antioxidant activity andcontain a flavonoid contents (47.74㎎/g) of the WHS flower. There was cytotoxicity at more than 250㎍/㎖ concentration ofWHS flower extract of RANKL-induced osteoclast in RAW264.7. There were no significant inhibited TRAP activity in theWHS leaf and stem. However, it was confirmed that it is significantly inhibited the differentiation activity of osteoclasts in 50and 100㎍/㎖ concentration of cells of stability levels of only WHS flower extracts (p<0.01). The WHS flower prominentlyinhibited RANKL-induced osteoclast differentiation activity by decreased calcitonin receptor and TRAP mRNA (p<0.01).These results indicate that of osteoclasts differentiation activity is inhibited by protection of oxidative stress due to the anti-oxidant activity of the WHS flower. Therefore, suggesting the WHS flower may be a presents the possibility as a preventiveand therapeutic agents for osteoporosis.
4.
2015.06
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This study was conducted to investigate the effects of sowing density, number of seeds sown per hole, andthinning treatment on growth characteristics and disease occurrence in Panax ginseng under direct sowing cultivation in ablue plastic greenhouse. Seedling were grown from 2 or 3 seeds sown, and the healthiest was only retained, while the restwere thinned out at the foliation stage. NO3-N, P2O5, and organic matter content differed significantly between growthconditions in the plastic greenhouse and in conventional shade in the soil. Disease also tended to be higher in the conven-tional shade than in the plastic greenhouse. Plant height and stem length showed an increasing trend with increasing sowingdensity and number of seeds sown per hole. However, these measures noticeably decreased when thinning treatment wasconducted. Growth of the subterranean part of ginseng was not markedly influenced by sowing density, the number of seedssown per hole, or thinning treatment. Root weight, which is an important factor in yield, was significantly affected by thenumber of seeds sown and thinning treatment. Interestingly, root weight tended to be higher in the thinning treatment plotthan the untreated control plot. Damping-off and root rot increased noticeably as the number of seeds sown increased. Dis-ease also tended to be substantially higher in the thinning treatment plot than the untreated control. However, physiologicaldisorder of the plants did not vary with sowing density, the number of seeds sown, or thinning treatment.
5.
2015.06
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The purpose of this study was to determine the possibility of using Wasabi japonica Matsum leaves as naturalhealth food source. To accomplish this purpose, the contents of general and antioxidative nutrients of Wasabi japonica Mat-sum leaves were measured. The contents of carbohydrate, crude protein, crude lipid and ash are 53.41%, 25.00%, 7.95%and 13.64%. And the calories of Wasabi leaves was 385.23Kcal. Total dietary fiber was 52.27%. The K was the largestmineral followed by Ca, P, Mg which means Wasabi leaves is alkali material. The contents of sinigrin and allyisothiocyanatein the wasabi leaves were 69.2㎎/g and 241.0㎎/g, respectively. Total phenol contents of the hot water extract and the 70%ethanolic extract were 19.44±0.23 and 19.33±1.17㎎ GAE/g, respectively. The total flavonoids content of the hot waterextract and the 70% ethanol extract were 7.69±0.71 and 19.25±1.41㎎ QE/g, respectively. The general nutrients andother antioxidant bioactive materials in Wasabi japonica Matsum leaves were also potential materials for good health food.
6.
2015.06
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This study was conducted to evaluate the growth conditions and vegetation of Peucedanum japonicum habitatin uninhabited islands of Incheon Korea. The emergence area of Peucedanum japonicum was 4.9m distance in coastline,and altitude and slope was 7.4m and 47.5%. Soil pH, organic matter and P2O5 of habitat were 7.1, 8.3% and 29.0㎎/㎏, andcontents of K, Ca, Mg and Na were 0.66, 4.9, 3.4 and 1.13cmol+/kg, respectively. Growth plants with Peucedanum japonicumwere total 55 taxa, and Gakeuldo in uninhabited islands was the most as 25 taxa. In growth plants with Peucedanumjaponicum, plants of over 25% frequence per plot were Miscanthus sinensis, Dendranthema boreale, Lilium lancifolium,Hemerocallis middendorffii, Elymus dahuricus, Cirsium japonicum var. maackii, Asparagus schoberioides, Gypsophila oldhamiana,Cocculus trilobus, Silene aprica var. oldhamiana, Artemisia capillaris, Crepidiastrum denticulatum and Sedum oryzifolium.The vegetation of Peucedanum japonicum habitat was classified into Aster spathulifolius community, Miscanthus sinensiscommunity, Dendranthema boreale community, Setaria viridis var. pachystachys community, Cirsium japonicum var. maackiicommunity and Hemerocallis middendorffii community. According to general condition of habitat, suitable growing areaswas determined to slightly acidic from mild alkaline soils.
7.
2015.06
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To study the effect of crop rotation on the control of ginseng root rot, growth characteristics and root rot ratioof 2-year-old ginseng was investigated after the crops of 18 species were cultured for one year in soil contaminated by thepathogen of root rot. Fusarium solani and Cylindrocarpon destructans were detected by 53.2% and 37.7%, respectively, frominfected root of 4-year-old ginseng cultivated in soil occurring the injury by continuous cropping. Content of NO3, Na, andP2O5 were distinctly changed, while content of pH, Ca, and Mg were slightly changed when whole plant of crops cultured forone year were buried in the ground. All of EC, NO3, P2O5, and K were distinctly increased in soil cultured sudangrass, pea-nut, soybean, sunnhemp, and pepper. All of EC, NO3, P2O5, and K among inorganic component showed negative effect onthe growth of ginseng when they were excessively applied on soil. The growth of ginseng was promoted in soil cultivatedperilla, sweet potato, sudangrass, and welsh onion, while suppressed in Hwanggi (Astragalus mongholicus), Deodeok(Codonopsis lanceolata) Doraji (Platycodon grandiflorum), Gamcho (Glycyrrhiza uralensis), Soybean. All of chicory, lettuce,radish, sunnhemp, and welsh onion had effective on the inhibition of ginseng root rot, while legume such as soybean,Hwanggi, Gamcho, peanut promoted the incidence of root rot. Though there were no significant correlation, NO3 showedpositive correlation, and Na showed negative correlation with the incidence of root rot.
8.
2015.06
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Skin anti-wrinkle activities of the stems and leaves of Abeliophyllum distichum Nakai were evaluated by theextracts obtained from various extraction processes such as using hot water at 100oC, 70% ethanol at 85oC, and 70% etha-nol with ultrasonication at 60oC The ultrasonicated extract showed 95.62% of the highest cell viability in addition of0.3㎎/㎖ of the extracts into the normal human fibroblast cell, CCD-986sk. For antioxidant activities, the extracts usingultrasonicated extract showed the highest DPPH free radical scavenging as 80.27%, followed by 75.88% and 62.44% for theextracts using ethanol extract and water extract. The ultrasonicated extract also showed the highest elastase inhibition activ-ity as 25.32%, compared to ethanol extract and water extract based method at 22.01% and 12.88%, respectively. MMP-1production was most effectively decreased down to 2908.1pg/㎖ with ultrasonicated extract while 6640.8pg/㎖ with waterextract and 3609.3pg/㎖ with ethanol extract, in addition of 0.3㎎/㎖. Collagen production was increased up to 154.7ng/㎖in addition of ultrasonicated extract, and followed by 121.4ng/㎖ and 31.2ng/㎖ for ethanol extract and water extract,respectively. These results indicate that the ethanol extract should have skin anti-wrinkling activities and can be improvedby the ultrasonication process that high energy input elute more amounts of bioactive substances eluting more amounts ofbioactive substances from the high energy input of ultrasonication.
9.
2015.06
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In this study, essential oils were extracted from the leaf of Chamaecyparis obtusa (CLEO), indigenous toKorea, CLEO constituents were analysed, and the effects of CLEO on airway hyperresponsiveness (AHR) and airwayinflammation (AI) were investigated in Ovalbumin (OVA)-induced asthma mouse model. Terpenoid components amongidentified CLEO constituents made up more than 80%. The CLEO-treated group in comparison to the control groupshowed reduced AHR, the decrease of eosinophil number in the bronchoalveolar lavage fluid (BALF), reduced specific anti-OVA IgE level in the serum, and a significant reduction in Th2 cytokines levels in the BALF with concentration. We con-cluded that CLEO have an alleviating effect on asthma-like symptoms such as AHR and AI. Further studies about antiasth-matic effect are necessary on the focus of single component of CLEO.
10.
2015.06
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This study was carried out to investigate the effects of Salvia plebeia R. Br. ethanolic extract with differentaspects (stem/leaf and whole plant) on differentiation and lipid accumulation in 3T3-L1 preadipocytes. The morphologicalchanges and the degrees of lipid accumulation in 3T3-L1 cells were measured by Oil Red O staining and intra-cellular trig-lyceride (TG) assay. The mRNA expressions of special peroxisome proliferation activated receptor- genes (PPAR), CCAAT/enhancer-binding protein (C/EBPα), fatty acid synthase (FAS) and lipoprotein lipase (LPL) were detected by reverse tran-scriptase polymerase chain reaction (RT-PCR). The 50% ethanolic extracts (100μg/mL) of stem and leaf (SALE) and 30%ethanolic extracts (100g/mL) of whole plant (SAE) from Salvia plebeia R. Br. were significantly attenuated lipid accumula-tion during adipogenesis in 3T3-L1 cells. Ethyl acetate-soluble fractions (50μg/mL) significantly inhibited lipid dropletaccumulation in 3T3-L1 cells. In addition, SALE induced down-regulation of specific adipogenic transcriptional factors (C/EBPα and PPARγ) and target genes (FAS and LPL) during adipogenesis. Salvia plebeia R. Br. may be used as a safe and effi-cient natural substance to manage obesity.
12.
2015.06
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Manuscript Editorial Board
14.
2015.06
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